Drho013615.1
Basic Information
- Insect
- Drosophila rhopaloa
- Gene Symbol
- -
- Assembly
- GCA_018152115.1
- Location
- JAECXI010000003.1:19408734-19410618[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.19 14 6.3 0.5 6 23 238 255 238 255 0.99 2 9 0.0067 0.49 10.9 1.0 1 23 261 284 261 284 0.97 3 9 5.9e-05 0.0043 17.4 1.5 1 23 292 314 292 314 0.97 4 9 7e-07 5.1e-05 23.4 3.3 2 23 321 343 321 343 0.98 5 9 1.1e-05 0.00082 19.6 0.7 1 23 350 373 350 373 0.97 6 9 0.058 4.2 8.0 0.2 2 23 383 404 382 404 0.95 7 9 0.088 6.4 7.4 0.3 2 23 414 435 413 436 0.93 8 9 9.2e-06 0.00067 19.9 3.6 1 23 441 463 441 463 0.98 9 9 0.00011 0.0076 16.6 3.7 1 23 469 492 469 492 0.97
Sequence Information
- Coding Sequence
- ATGATATGCCGCCTCTGCCTGGACGATGCGGAGCACAGCGTGCCTATCTTTGACCAGGAGGACACCACCGACCAACCGGTGCCCTCCAACCTGGCGGAACTCATTGAGAAGCACCTGCAGTTGGTGCTCCTGCCCAACGATGCGGTGTCCAAGTGCCTGTGCACCCAGTGCTGGCAGCAGTTGGCCGACTTCGAACAGTTCTGCGCCATGGTGATGAAGAAGCAGCTGGGCCTGCAGCATCTGAAGATGGAGCCCTTTTCGGAGGACGAGGATGCGGACACAAAGGCGCAGATCCTGTGCGAACCAGAGATCGACGTGAGTCCTGCGGCAGCAGACAATGAGGAGTGCAACGAGATCGACGGAGATGCCAGCAGCAGGAGCAGTAGTATCCGGCCAACCAGCCGACGGAAGATGCGTTTGCCATCGCCCATCAGACGCAGCATGCGACCCCGCGCCGCCACAACTCCCAAGACCCGAATCATTAAGGCCAAGGCCAAGACGAAGCGCCACCAAGAGGAGGCGGACGAGGATGAGGATGCCGAGGGTGATCCGGAGACCCGGAGCAGCAACAGCCGGGAGATGGACAGCTACATCGCTTTGCACGGCCGTTTAGAGTGCTGCATGTGCGGCGGCGACGATCAGTTCCAGAACTTTGCCGAGATGAAGCGGCATTTCCGGAATCAGCACCAATCCGCCGGGTATGTGGTCTGCTGTCAACGGCGCTACAAGAAGCGAGCCCTCTACGTGGACCATCTCCGCATGCACAACGATCCGGACTACTTTAGGTGCAAGATCTGTTCCAAGCAGCTGGTCAGCCGGATTAGCTACGACGTACACATGCTGCGCTTCCACTCTAACGAGGACGAGCTGAGCTTCGCCTGCGATCAGTGCTCCAAGCGGTTCTCCAAACAGTTTCTGCTCACCATCCACTCAAGAGTGCACCAGCAGGAAAGAAAGGAGCAGTGCAAGCACTGCGACAGATCCTTCCGTACCGCCGTTGACCTGCGACTGCACATGCGACGCACCCATGACCCCGCCTTCGTGCCCTTCATCTGTGACTCGTGCGGCGCCAAGTTCAAGACGAAGCAGAACCTGCTGGTTCACAAACGCACCGTGCACCGCGAGGGCTCTCAGCTACCGGAGGTCCAGTGCCAGGAGTGTCAGGTGTGGCTGTCCGATGAGAATAGCCTGCGCAAGCACATGTATATGCACCTGGATGCCGCCTCGTTACGGCAGTGGAAGTGCGAGCAGTGCGGCCTGGAAAAGGGGTCGCGGGCAAAGCTGGCGGCGCACATACGCTACCATCACCCAAAGGAGTTCCACAAGTGCTCGCACTGCGGCAAGGAGTTCAAAAGCAGCCGCGGACTGGAGGAGCACACGGCCACGCACACCGGCCAGGATCTGTACGAGTGCGCCTTCTGCGAGCGCACCTTCAAGAACTCTGGAAACATGCATAAGCACCGCCGCCAAATGCACGCCGCCCAGGTGGCCGCGCTGCAGCAGCAGAAGAAGGTGCGGCCCAGCAAGCGCAAGGACAAGGGCGACCTGCTGCTCGACGTCCTGGCCGCCAGCGGAAAGGAACTGGACCACACCATGGGAGTGGGCGACATGAACGACTGA
- Protein Sequence
- MICRLCLDDAEHSVPIFDQEDTTDQPVPSNLAELIEKHLQLVLLPNDAVSKCLCTQCWQQLADFEQFCAMVMKKQLGLQHLKMEPFSEDEDADTKAQILCEPEIDVSPAAADNEECNEIDGDASSRSSSIRPTSRRKMRLPSPIRRSMRPRAATTPKTRIIKAKAKTKRHQEEADEDEDAEGDPETRSSNSREMDSYIALHGRLECCMCGGDDQFQNFAEMKRHFRNQHQSAGYVVCCQRRYKKRALYVDHLRMHNDPDYFRCKICSKQLVSRISYDVHMLRFHSNEDELSFACDQCSKRFSKQFLLTIHSRVHQQERKEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNLLVHKRTVHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPKEFHKCSHCGKEFKSSRGLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVRPSKRKDKGDLLLDVLAASGKELDHTMGVGDMND
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00609377;
- 90% Identity
- iTF_00537021;
- 80% Identity
- -