Basic Information

Insect: Drosophila rufa
Gene Symbol: -
Assembly: GCA_018153105.1
Location: JAECXS010000111.1:13741567-13743437[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.21 13 6.2 0.5 6 23 255 272 255 272 0.99

2 9 0.0073 0.46 10.8 1.0 1 23 278 301 278 301 0.97

3 9 5e-05 0.0032 17.6 1.8 1 23 309 331 309 331 0.97

4 9 7.6e-07 4.8e-05 23.4 3.3 2 23 338 360 338 360 0.98

5 9 1.2e-05 0.00078 19.5 0.7 1 23 367 390 367 390 0.97

6 9 0.063 4 7.9 0.2 2 23 400 421 399 421 0.95

7 9 0.096 6.1 7.3 0.3 2 23 431 452 430 453 0.93

8 9 9.4e-06 0.0006 19.9 3.7 1 23 458 480 458 480 0.98

9 9 0.00011 0.0072 16.5 3.7 1 23 486 509 486 509 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.21	13	6.2	0.5	6	23	255	272	255	272	0.99
2	9	0.0073	0.46	10.8	1.0	1	23	278	301	278	301	0.97
3	9	5e-05	0.0032	17.6	1.8	1	23	309	331	309	331	0.97
4	9	7.6e-07	4.8e-05	23.4	3.3	2	23	338	360	338	360	0.98
5	9	1.2e-05	0.00078	19.5	0.7	1	23	367	390	367	390	0.97
6	9	0.063	4	7.9	0.2	2	23	400	421	399	421	0.95
7	9	0.096	6.1	7.3	0.3	2	23	431	452	430	453	0.93
8	9	9.4e-06	0.0006	19.9	3.7	1	23	458	480	458	480	0.98
9	9	0.00011	0.0072	16.5	3.7	1	23	486	509	486	509	0.97

Sequence Information

Coding Sequence: ATGATTTGCCGACTTTGTCTGGACGATGCGGTGCACAGCATCCCGATCTTCGACCAGGAGGAGGCCGACGACCAGCCGCCGCCCTCCAACCTGGCGGAGCTGATTGAGAAGCACCTGCAGTTGGTCCTGCTGCCCAACGATGCTGTGTCCCGGTGCCTGTGCACCCAGTGCTGGCAGCAACTGGCCGACTTTGAGCAATTCTGCACCATGGTGATGAAGAAGCAGCTGGGCCTGCAGCAGCTCAAGCTGGAGGCCTTCTCCGACGAGGACGAGGACGCGGACGCGGACACGAAGGCGCATATCTTGTGCGAGCCGGAGATCGATGTGAGTCCCTCGGCGGCGGAGAACGAGGAGTACAACGAGATCGATGTGGATGCCACCAGCAGTAGCAGCAACACACACGCTGCAGGGGCACCGACTGGTGGACGGGCGACAACGCGGCGCACGAGGGTGCGTCTGCCGTCGCCCATCAGACGCAGCATGCGTCCCCGAGCGCTGCCAAAGGCCAGGGCCGTCAAGGCCACCAAGGCCAAGACGAAGCGCCAGCTGGAGGAGGCGGACGAGGATGAGGACGCCGAGGGCGACGGTGATGGGGATGCCGAGAGCCGGAGCAGCCACAGCCGCGAAATGGATAGCTACATAGCGGTGCACGGCCGCCTGGAGTGTTGCTTGTGCGGCGGCGACGACGACCAGTTCCAGAACTTTGCCGAGATGAAGCGGCACTTCCGCAATCATCACCAGTCCGCCGGCTACGTGGTGTGCTGCCAGCGACGCTACAAGAAGCGGGCGCTCTACGTCGACCACCTGCGCATGCACAACGATCCGGACTACTTTAGGTGCAAGATCTGCTCCAAGCAGCTGGTCAGCCGGATCAGCTACGACGTCCACATGCTGCGCTTCCACTCCAACGAGGACGAGCTGAGCTTCGCCTGCGACAAGTGCTCCAAGCGGTTCTCCAAGCAATTCCTGCTCACCATCCATTCGCGAGTGCACCAGCAGGAGCGGAAGGAGCAGTGCAAGCACTGCGACAGATCCTTCCGCACTGCCGTGGACCTGCGCCTGCATATGCGACGCACCCATGACCCCGCCTTCGTGCCCTTCATCTGCGACTCGTGCGGCGCCAAGTTCAAGACGAAACAGAACCTGCTCGTTCACAAGCGCACCGTGCACCGCGAGGGCTCCCAGCTGCCGGAGGTGCAGTGCCAGGAGTGCCAGGTGTGGCTATCCGACGAGAACAGCCTGCGCAAGCACATGTACATGCACCTGGACGCCGCCTCGCTGCGCCAGTGGAAGTGCGAGCAGTGCGGCTTGGAGAAGGGCTCGCGAGCGAAGCTGGCGGCCCACATCCGCTACCACCATCCAAAGGAATACCACAAGTGCACGCACTGCGGCAAGGAGTTCAAGAGCAGCCGCGGGCTCGAGGAGCACACGGCCACGCACACCGGCCAGGATCTGTACGAGTGCGCCTTCTGCGAGCGCACCTTCAAGAATTCGGGCAACATGCACAAGCACCGCCGCCAGATGCACGCCGCCCAGGTGGCCGCCCTCCAGCAGCAGAAGAAGGTGCGTCCCAGCAAGCGTAAGGACAAGGGCGAGCTGATGCTCGGTGTCCTGGCCGCCGGCGGAAAGGACATGATGGATCATGCTATGGGAACCGCCGGCGACATGAACATGAATATGAACATAAACGACTGA
Protein Sequence: MICRLCLDDAVHSIPIFDQEEADDQPPPSNLAELIEKHLQLVLLPNDAVSRCLCTQCWQQLADFEQFCTMVMKKQLGLQQLKLEAFSDEDEDADADTKAHILCEPEIDVSPSAAENEEYNEIDVDATSSSSNTHAAGAPTGGRATTRRTRVRLPSPIRRSMRPRALPKARAVKATKAKTKRQLEEADEDEDAEGDGDGDAESRSSHSREMDSYIAVHGRLECCLCGGDDDQFQNFAEMKRHFRNHHQSAGYVVCCQRRYKKRALYVDHLRMHNDPDYFRCKICSKQLVSRISYDVHMLRFHSNEDELSFACDKCSKRFSKQFLLTIHSRVHQQERKEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNLLVHKRTVHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPKEYHKCTHCGKEFKSSRGLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVRPSKRKDKGELMLGVLAAGGKDMMDHAMGTAGDMNMNMNIND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609377;
90% Identity: iTF_00609377;
80% Identity: -