Basic Information

Insect: Drosophila subobscura
Gene Symbol: ken1_1
Assembly: GCA_008121235.1
Location: NC:21059628-21062029[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0006 0.036 14.1 2.6 2 23 201 222 200 222 0.97

2 12 0.015 0.87 9.7 0.1 1 23 228 253 228 253 0.90

3 12 0.045 2.7 8.2 0.1 3 23 262 285 260 285 0.93

4 12 0.00066 0.039 14.0 0.9 2 23 298 319 297 319 0.96

5 12 8.4e-06 0.0005 19.9 0.6 1 23 326 348 326 348 0.98

6 12 0.0021 0.13 12.4 0.2 1 23 354 376 354 376 0.98

7 12 0.0056 0.33 11.1 2.0 1 23 382 405 382 405 0.97

8 12 0.009 0.54 10.4 4.0 1 23 411 433 411 433 0.96

9 12 0.00076 0.045 13.8 2.9 2 23 440 461 439 461 0.96

10 12 9.7e-05 0.0058 16.6 1.2 3 23 552 573 550 573 0.95

11 12 0.0027 0.16 12.1 1.1 1 19 579 597 579 601 0.95

12 12 3.6e-06 0.00021 21.1 1.0 1 23 607 629 607 629 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0006	0.036	14.1	2.6	2	23	201	222	200	222	0.97
2	12	0.015	0.87	9.7	0.1	1	23	228	253	228	253	0.90
3	12	0.045	2.7	8.2	0.1	3	23	262	285	260	285	0.93
4	12	0.00066	0.039	14.0	0.9	2	23	298	319	297	319	0.96
5	12	8.4e-06	0.0005	19.9	0.6	1	23	326	348	326	348	0.98
6	12	0.0021	0.13	12.4	0.2	1	23	354	376	354	376	0.98
7	12	0.0056	0.33	11.1	2.0	1	23	382	405	382	405	0.97
8	12	0.009	0.54	10.4	4.0	1	23	411	433	411	433	0.96
9	12	0.00076	0.045	13.8	2.9	2	23	440	461	439	461	0.96
10	12	9.7e-05	0.0058	16.6	1.2	3	23	552	573	550	573	0.95
11	12	0.0027	0.16	12.1	1.1	1	19	579	597	579	601	0.95
12	12	3.6e-06	0.00021	21.1	1.0	1	23	607	629	607	629	0.98

Sequence Information

Coding Sequence: ATGGATATGGTCGCACGGGAGCCATATCCCGTCCACTCACTATGCCGCCTCTGCCTGACGTGCCTGGAGCAGGGCCCCGCCCACGATCTGTTTCTGGAGCCAGATCTGGCCAAAAAGCTAACACTCTGCACCGCCCTCGATGTGGACCAGCAGGATGGATTTCCCCGGAGCATCTGCAATGGATGCTTTGGGCAGCTGAACGACCTGCAAGCGTTCCAAAAAGTATGCCTTGACTCTGTGCAACGTTTCAAGGATATGGTGGCCGCCAACAGAATCGTCGCCATCGAATTGTTGGAGCCGGTGGCCGAGCAGCCAGCGGAGGTGATTGTGGGACCGGAGGAGCAGGCCAGCTATGATCCGCTGCTAAATCACAAGCTGGAGATGATTgagaacgaggaggaggtCTTCAAGATGCTGGTGACGGTGGACAAGAGCGTTTTCTCAGACTTCACTTCCGAAGAGAACGaagacgacgaggaggagatgaCTGCGGATGGCTCCACCGACGACGAACTGCCATTGGCCCATCGTTTGCTGTCCAAGGAGCGGGCAAAGCGAAAAAAGATTCCACCTGAAGAGCGTCGCCTGCGTCGTATCATCACCTGCACCGTCTGCCAGCAAAAGTTCAAGAAACAATCGAAATTCGATGAGCACATGAAGTACCACAACGATCTGCTGCCCTTCCAGTGCGCGGAGGAGTCATGCCGGAAGGGCTTCACCACAGCCGGTGCACTGCGTCTGCATGTGGACTATGCGCACACGAGGAAAGCCGATGAGATACCTTGCACCGTGGAGGGCTGCAAGCTGCTGTTTCCCCGCCTGCGGCTGCTCACCATTCACCTGAAGAAGGTGCACAACCAGACGCGGGTGAGTGCACCGCGGGCGGAGCAGCCCTGCGGCGAGTGTGGCATGGTCTTCCGCTGTCAGGTGGCACTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCGTACCCCTGCAACATCTGCGGCAAGGGATTCCACATAAATAGCGCCCTGAAGAACCATCTGCTGCGGCATGCGGGCATCAAGAACTACGTCTGCCCGTACTGCGGCGTGGGCAAGACCACGCGCCAGGAGTGGAGCAAGCACATGCTGACCCACACCCAGGAGAAGCAGTTCAAGTGCCCCACCTGCGACCATGCCACGCACACAAAGCGAGCGCTCGACAATCATGTGAAGATCGTACACGAGAAGGTCCGAAACTTTGCCTGCCAGTACTGTGGGAAGACGTTCGGCAAGTCGCATGCCTGCAAGATCCACGAGATGACGCACACGGGAGAGAAGCGCTGCGAGTGCAAGGTCTGTGGCAAGAAGTTCCTCTACACCGAAAGCCTCACGAAACACCTGAAGATCCACGAGAAGAGCGTGGAGCGTGCCTTGGAGACGTATCGCCAGCGGCAGGGAGAGACGAACAGCGCTGACCAGGACCAAGTCCAAGTGGATGCCAATCACCTGATGAAAGTCTGCGCCGAATCGGTGGCCACAATTCCGCGGGATCCGCGACGCGTGGAGCGCGTTGACATGGCCCAGCTGGCGGGCACCGTGGTGAATCCCATACCCATCGTCTCAGTGCCTTCCAGTGCGCCGCCGCAGGCCAAGTTCGTGCAGAAGGAGGGCATGCATCTGTGCCCGGGCTGCAATCAGGGCTTCAACAATCTGGGCAACATGAAGCGCCACTACAAGAGCATCCACGAGAAGGTCAAAGACTTTGAGTGCCGCTTCTGTTCGCGTCGCTTCGCCAATTCGCAGTCGCTCAAGCAGCACGAGTGGATACACACTGGTGAGAAGCCTTACGCCTGCAAGACCTGCGGCACACACTTCCGCCAGGAGGCGGCGCTCATACGCCACCAAAAGGTGCACGACGAAAAGCCACCACGGCCAGCGAAGCCGCCCAAGGAAATCACAGACAAAGCGCgccagaagctgctgcagaggTCCGAGCGCAGGCGCGAAGTGGAGGCGCTGCGCCAGGAGATAGCCCAGGCCGCCAAGGAGGAACTGAAAGATCTGGAAAAGCAGCGGGCActggagaaggagcagaaTACATACGAAAAGTATCAGGCAGCGGCCGAGACAACTTGA
Protein Sequence: MDMVAREPYPVHSLCRLCLTCLEQGPAHDLFLEPDLAKKLTLCTALDVDQQDGFPRSICNGCFGQLNDLQAFQKVCLDSVQRFKDMVAANRIVAIELLEPVAEQPAEVIVGPEEQASYDPLLNHKLEMIENEEEVFKMLVTVDKSVFSDFTSEENEDDEEEMTADGSTDDELPLAHRLLSKERAKRKKIPPEERRLRRIITCTVCQQKFKKQSKFDEHMKYHNDLLPFQCAEESCRKGFTTAGALRLHVDYAHTRKADEIPCTVEGCKLLFPRLRLLTIHLKKVHNQTRVSAPRAEQPCGECGMVFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCPTCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETNSADQDQVQVDANHLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPIPIVSVPSSAPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDEKPPRPAKPPKEITDKARQKLLQRSERRREVEALRQEIAQAAKEELKDLEKQRALEKEQNTYEKYQAAAETT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536218;
90% Identity: iTF_00515060; iTF_00474682; iTF_00536218; iTF_00603523; iTF_00564102; iTF_00517895; iTF_00575015; iTF_00580939; iTF_00473961; iTF_00611507; iTF_00481014; iTF_00471808; iTF_00484583;
80% Identity: -