Basic Information

Insect: Drosophila athabasca
Gene Symbol: ken1
Assembly: GCA_008121215.1
Location: CM017796.1:44125713-44127983[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00035 0.024 14.9 2.6 2 23 210 231 209 231 0.97

2 12 0.00067 0.046 14.0 0.2 1 23 237 262 237 262 0.93

3 12 0.049 3.3 8.1 0.1 3 23 271 294 269 294 0.93

4 12 0.00067 0.046 14.0 0.9 2 23 307 328 306 328 0.96

5 12 8.6e-06 0.00058 19.9 0.6 1 23 335 357 335 357 0.98

6 12 0.0022 0.15 12.4 0.2 1 23 363 385 363 385 0.98

7 12 0.045 3.1 8.2 2.0 1 23 391 414 391 414 0.97

8 12 0.0092 0.63 10.4 4.0 1 23 420 442 420 442 0.96

9 12 0.00078 0.053 13.8 2.9 2 23 449 470 448 470 0.96

10 12 9.9e-05 0.0068 16.6 1.2 3 23 560 581 558 581 0.95

11 12 0.0027 0.19 12.0 1.1 1 19 587 605 587 609 0.95

12 12 3.7e-06 0.00025 21.1 1.0 1 23 615 637 615 637 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00035	0.024	14.9	2.6	2	23	210	231	209	231	0.97
2	12	0.00067	0.046	14.0	0.2	1	23	237	262	237	262	0.93
3	12	0.049	3.3	8.1	0.1	3	23	271	294	269	294	0.93
4	12	0.00067	0.046	14.0	0.9	2	23	307	328	306	328	0.96
5	12	8.6e-06	0.00058	19.9	0.6	1	23	335	357	335	357	0.98
6	12	0.0022	0.15	12.4	0.2	1	23	363	385	363	385	0.98
7	12	0.045	3.1	8.2	2.0	1	23	391	414	391	414	0.97
8	12	0.0092	0.63	10.4	4.0	1	23	420	442	420	442	0.96
9	12	0.00078	0.053	13.8	2.9	2	23	449	470	448	470	0.96
10	12	9.9e-05	0.0068	16.6	1.2	3	23	560	581	558	581	0.95
11	12	0.0027	0.19	12.0	1.1	1	19	587	605	587	609	0.95
12	12	3.7e-06	0.00025	21.1	1.0	1	23	615	637	615	637	0.98

Sequence Information

Coding Sequence: ATGGATATGATTGCAAGAGAGCCATATCCGGTCAACTCAATATGCCGCCTCTGTCTGATGTACCTGGACCAGAGCCCCTCTCACGATCTATATCTGGAGCCAGATCTGGCCAAAAAGCTAATCCTTTGCACAACCCTCGATGTGGACCAGCAGGATGGGTTTCCCCGGAGCATCTGCAATGGATGCTTTGGAAAATTGAACGAGTTGCAAGAGTTTCAAAAACTATGCCTGGACTCTGTGCAGCGTTTCAAGGAAATGGTGGCCGCCAATAGAATCATCACAATCGAATTATTAGAGCCGGTGGCGGAACAGCCAGCGGAGGTGATTGTAGGCCCGGAGGAGCAGGCTAGCTATGATCCCCTGCTTAATCATAAGCTTGAGATGATTGAGAACGAGGAGGAGGTTTTCAAGATGCTGGTGACTGTGGACAAGAGCGTTTTCTCCGACTACACATCCGATGAGAacgacgatgaggaggaggaggtgaagGATGGCGAAGAaaagagctccactgatgACGATCTGCCATTGGCATATCGATTACAGGGCGAAGAAGAGGAGACGTCCAAGGAACGGGCAAAGCGAAAAAAGATTCCACCTGCCGAGCGTCGCCTTCGCCGTATCATCACCTGCACCATCTGCCagcaaaagttcaaaaagCAGTCGAAATTCGACGAGCATATGAAGTATCACAACGACCTCCTGCCCTTCCAGTGTACAGAGGAGACCTGCAAGAAGGGCTTCACCACAGCCGGCGCACTACGTCTCCATGTGGACTATGCGCACACCAGGAAAGCCGATGAGATACCGTGCACCGTGGAGGGGTGTAAGTTTCTGTTTCCCCGCCTGAGGCTGCTCACCATTCACCTGAAGAAGGTCCACAACCAGACGCGAGTGAGTGTCCCGCGAGCGGAGCAGCCTTGCGGCGAGTGTGGCATGGTCTTCCGCTGTCAGGTGGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGGAGTTGCCCTACCCTTGCAACATCTGCGGCAAGGGATTCCACATCAACAGCGCCCTCAAGAACCATCTGCTGCGGCATGCGGGCATCAAGAACTACGTCTGTCCGTACTGCGGCGTGGGCAAGACAACGCGCCAGGAGTGGAGCAAGCACATGCTGACCCACACCCAGGAGAAGCAGTTCAAGTGTGCCACCTGCGACCATGCCACGCACACAAAGCGAGCGCTCGACAATCATGTGAAGATCGTCCACGAGAAGGTCCGAAACTTTGCCTGCCAGTACTGCGGGAAGACGTTCGGCAAGTCGCATGCCTGCAAAATCCATGAGATGACACACACGGGGGAGAAGCGGTGCGAGTGCAAGGTATGTGGAAAGAAGTTCCTGTACACCGAGAGCCTCACAAAACACCTGAAGATACACGAGAAGAGCGTGGAGCGAGCCTTGGAGACGTATCGCCAGCGGCAGGGAGAGACCACTGCcgaccaggaccaggcccaAGTGGATGCCAATCACCTGATGAAAGTCTGCGCCGAATCGGTAGCCACAATTCCTCGGGATCCGCGCCGCGTTGAACGCGTTGATATGGCCCAATTAGCGGGCACTGTGGTGAATCCCATTCCCACCGTTTCGCTGCCCTCTAGTGCGCCGCCCCAGGCAAAGTTCGTCCAGAAGGAGGGCATGCATCTGTGCCCGGGATGCAACCAGGGATTCAACAATCTGGGTAACATGAAGCGACACTACAAAAGCATCCACGAGAAGGTCAAAGACTTTGAGTGCCGCTTCTGTTCGCGTCGCTTCGCCAACTCGCAGTCGCTCAAGCAGCACGAGTGGATACACACGGGGGAGAAGCCCTACGCCTGCAAGACCTGTGGTACCCACTTCCGCCAGGAGGCGGCTCTCATCCGCCACCAAAAGGTGCACGACGAAAAGCCACCCAGGCCGGCAAAACCGCCTAAGGAAATCACAGACAAGGCACGCCAGAAGCTGCTGCAGAGGTGCGAGCGGAAGCGCAAGGTGGAGGCACTACGTCAGGAGATAGCCCAGGCTGCCAAGGAGGAGCTGAAGGACTTGGAAAAGCAGCGAGCCCTGGAGAAGGAGCAGAATACCTATGAAAAGTATCAGGCAGCTGCAGAGGCGGTGGGTACCACCTCAACTGAAAGTTGA
Protein Sequence: MDMIAREPYPVNSICRLCLMYLDQSPSHDLYLEPDLAKKLILCTTLDVDQQDGFPRSICNGCFGKLNELQEFQKLCLDSVQRFKEMVAANRIITIELLEPVAEQPAEVIVGPEEQASYDPLLNHKLEMIENEEEVFKMLVTVDKSVFSDYTSDENDDEEEEVKDGEEKSSTDDDLPLAYRLQGEEEETSKERAKRKKIPPAERRLRRIITCTICQQKFKKQSKFDEHMKYHNDLLPFQCTEETCKKGFTTAGALRLHVDYAHTRKADEIPCTVEGCKFLFPRLRLLTIHLKKVHNQTRVSVPRAEQPCGECGMVFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCATCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETTADQDQAQVDANHLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPIPTVSLPSSAPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDEKPPRPAKPPKEITDKARQKLLQRCERKRKVEALRQEIAQAAKEELKDLEKQRALEKEQNTYEKYQAAAEAVGTTSTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536218;
90% Identity: iTF_00601216;
80% Identity: -