Basic Information

Insect: Drosophila lowei
Gene Symbol: ken1
Assembly: GCA_008121275.1
Location: CM017781.1:2494720-2496951[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00025 0.019 15.3 1.6 2 23 211 232 210 232 0.96

2 12 0.0015 0.11 12.8 0.1 1 23 238 263 238 263 0.93

3 12 0.049 3.6 8.1 0.1 3 23 272 295 270 295 0.93

4 12 0.00067 0.05 14.0 0.9 2 23 308 329 307 329 0.96

5 12 8.5e-06 0.00063 19.9 0.6 1 23 336 358 336 358 0.98

6 12 0.0021 0.16 12.4 0.2 1 23 364 386 364 386 0.98

7 12 0.045 3.3 8.2 2.0 1 23 392 415 392 415 0.97

8 12 0.0091 0.68 10.4 4.0 1 23 421 443 421 443 0.96

9 12 0.00077 0.058 13.7 2.9 2 23 450 471 449 471 0.96

10 12 9.9e-05 0.0074 16.6 1.2 3 23 561 582 559 582 0.95

11 12 0.0027 0.2 12.0 1.1 1 19 588 606 588 610 0.95

12 12 3.7e-06 0.00027 21.1 1.0 1 23 616 638 616 638 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00025	0.019	15.3	1.6	2	23	211	232	210	232	0.96
2	12	0.0015	0.11	12.8	0.1	1	23	238	263	238	263	0.93
3	12	0.049	3.6	8.1	0.1	3	23	272	295	270	295	0.93
4	12	0.00067	0.05	14.0	0.9	2	23	308	329	307	329	0.96
5	12	8.5e-06	0.00063	19.9	0.6	1	23	336	358	336	358	0.98
6	12	0.0021	0.16	12.4	0.2	1	23	364	386	364	386	0.98
7	12	0.045	3.3	8.2	2.0	1	23	392	415	392	415	0.97
8	12	0.0091	0.68	10.4	4.0	1	23	421	443	421	443	0.96
9	12	0.00077	0.058	13.7	2.9	2	23	450	471	449	471	0.96
10	12	9.9e-05	0.0074	16.6	1.2	3	23	561	582	559	582	0.95
11	12	0.0027	0.2	12.0	1.1	1	19	588	606	588	610	0.95
12	12	3.7e-06	0.00027	21.1	1.0	1	23	616	638	616	638	0.98

Sequence Information

Coding Sequence: ATGGATATGGTTGCAAGCGAACCATATCCCGCCAACTCAATATGCCGCCTTTGTCTGATGTACCTGGACCAGAGCGCCGCCCACGATCTCTATCTGGAgccagatctggccaaaaAGCTAACCCTCTGCACCACCCTCGATGTGGACCAGCAGGATGGCTTTCCCCGGAGCATCTGCAATGGATGCTTTGGGAAATTGAACGAGTTGCAAGAGTTTAAAAAACTATGCCTGGACTCTGTGCAGCGATTCAAGGAAATGGTGGCCGCCAACAGAATCATCCCCATCGAATTGTTGGAGCCGGTGGCGGAACAGGCAGCGGAAGTGATTGTAGGGCCGGAGGAGCAGGCTAGCTATGACCCACTGCTAAATCATAAGCTGGAGATGATTGAGAACGAGGAGGAGGTTTTCAAGATGCTGGTGACTGTGGACAAGAGCGTTTTCTCCGACTACACAtccgatgaggaggaggaggaggaggaggaggaggatggcgAAGagaagagctccactgatgaCGAGCTTCCATTGGCCCGTCGTTTGctgggagagggagaaagagaggagaCGGCCAAGGAACGGGCAAAGCGAAAAAAGATTCCACCTGCCGAGCGTCGCCTCCGTCGTATCATCCCCTGCACCATTTGCCAGCAAAAGTTCAAGAAGCAATCGAAATTCGACGAGCACATGAAGTATCACAACGACCTCCTGCCCTTCCAGTGCACAGAGGAGACCTGCCGAAAAGGATTCACCACAGCCGGCGCACTGCGTCTCCATGTAGACTATGCGCACACCAGGAAAGCGGATGAGATACCCTGCACCGTGGAAGGGTGCAAGTTTCTGTTTCCCCGGCTGCGGCTGCTCACCATTCACTTGAAGAAAGTCCACAACCAGACGCGGGTGAGTGCTCCGCGAGCGGAGCAGCCGTGCGGCGAGTGTGGCATGGTCTTCCGCTGTCAGGTGGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGGAGTTGCCCTACCCTTGCAACATCTGCGGCAAGGGATTCCACATCAACAGCGCCCTCAAGAACCATCTGCTGCGGCATGCGGGCATCAAGAACTACGTCTGTCCGTACTGCGGCGTGGGCAAGACGACACGACAGGAGTGGAGCAAGCACATGCTGACCCACACCCAGGAAAAGCAGTTCAAGTGTGCCACCTGCGACCATGCCACGCACACAAAGCGTGCGCTCGACAATCATGTGAAGATCGTCCACGAGAAGGTCCGAAACTTTGCCTGCCAGTACTGCGGGAAGACGTTCGGCAAGTCGCATGCCTGCAAAATCCATGAGATGACACACACGGGGGAGAAGCGGTGTGAGTGCAAGGTCTGCGGAAAGAAGTTCCTGTACACCGAGAGCCTCACAAAGCACCTGAAGATACACGAGAAGAGCGTGGAGCGAGCCTTGGAGACGTATCGTCAGCGGCAGGGAGAGACCACCGCcgaccaggaccaggcccaAGTGGATGCCAATCACCTGATGAAAGTCTGCGCCGAGTCGGTGGCCACAATCCCTCGGGATCCGCGACGCGTTGAACGTGTTGATATGGCCCAATTAGCGGGCACAGTGGTTAATCCCATTTCCAGTGTATCGCTGCCCGCCAGCTCGCCGCCCCAGGCAAAGTTTGTCCAGAAGGAGGGCATGCATCTGTGCCCGGGGTGTAATCAGGGATTCAATAATCTGGGGAACATGAAGCGACACTACAAGAGCATCCACGAGAAGGTCAAAGACTTTGAGTGTCGCTTCTGTTCGCGTCGCTTCGCCAACTCGCAGTCGCTCAAGCAGCACGAGTGGATACACACGGGGGAGAAGCCCTACGCCTGCAAGACCTGTGGCACCCACTTCCGCCAGGAGGCGGCTCTCATCCGCCACCAAAAGGTGCACGACGAAAAGCCACCCAGGCCGGCGAAACCCCCTAAGGAGATCACAGACAAGGCACGCcagaagctgctgcagaggtGCGAGCGCAAGCGCAAGGTGGAGGCACTGCGTCAGGAGATAGCTCAGGCCGCCAAGGAGGAGCTGAAGGACTTGGAAAAGCAGCGAGCCTTGGAGAAGGAGCAGAATACCTATGAAAAGTATCAGGCAGCTGCCGAGGCGGTGGCCACCACCCCAACTGGAAGTTGA
Protein Sequence: MDMVASEPYPANSICRLCLMYLDQSAAHDLYLEPDLAKKLTLCTTLDVDQQDGFPRSICNGCFGKLNELQEFKKLCLDSVQRFKEMVAANRIIPIELLEPVAEQAAEVIVGPEEQASYDPLLNHKLEMIENEEEVFKMLVTVDKSVFSDYTSDEEEEEEEEEDGEEKSSTDDELPLARRLLGEGEREETAKERAKRKKIPPAERRLRRIIPCTICQQKFKKQSKFDEHMKYHNDLLPFQCTEETCRKGFTTAGALRLHVDYAHTRKADEIPCTVEGCKFLFPRLRLLTIHLKKVHNQTRVSAPRAEQPCGECGMVFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCATCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETTADQDQAQVDANHLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPISSVSLPASSPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDEKPPRPAKPPKEITDKARQKLLQRCERKRKVEALRQEIAQAAKEELKDLEKQRALEKEQNTYEKYQAAAEAVATTPTGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00473961; iTF_00603523; iTF_00564102; iTF_00517895; iTF_00575015; iTF_00580939; iTF_00611507; iTF_00515060; iTF_00474682; iTF_00487482; iTF_00471808; iTF_00484583; iTF_00481014; iTF_00601216;
90% Identity: iTF_00601216;
80% Identity: -