Basic Information

Insect: Drosophila algonquin
Gene Symbol: ken1
Assembly: GCA_035041765.1
Location: JAWNKY010002737.1:1656450-1658682[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 6.7e-05 0.0056 17.3 2.6 2 23 213 234 212 234 0.97

2 12 0.00059 0.049 14.3 0.2 1 23 240 265 240 265 0.93

3 12 0.055 4.6 8.1 0.1 3 23 274 297 272 297 0.93

4 12 0.00075 0.062 13.9 0.9 2 23 310 331 309 331 0.96

5 12 9.6e-06 0.0008 19.9 0.6 1 23 338 360 338 360 0.98

6 12 0.0024 0.2 12.4 0.2 1 23 366 388 366 388 0.98

7 12 0.051 4.2 8.2 2.0 1 23 394 417 394 417 0.97

8 12 0.01 0.86 10.4 4.0 1 23 423 445 423 445 0.96

9 12 0.00088 0.073 13.7 2.9 2 23 452 473 451 473 0.96

10 12 0.00011 0.0093 16.6 1.2 3 23 563 584 561 584 0.95

11 12 0.0031 0.25 12.0 1.1 1 19 590 608 590 612 0.95

12 12 4.1e-06 0.00034 21.1 1.0 1 23 618 640 618 640 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	6.7e-05	0.0056	17.3	2.6	2	23	213	234	212	234	0.97
2	12	0.00059	0.049	14.3	0.2	1	23	240	265	240	265	0.93
3	12	0.055	4.6	8.1	0.1	3	23	274	297	272	297	0.93
4	12	0.00075	0.062	13.9	0.9	2	23	310	331	309	331	0.96
5	12	9.6e-06	0.0008	19.9	0.6	1	23	338	360	338	360	0.98
6	12	0.0024	0.2	12.4	0.2	1	23	366	388	366	388	0.98
7	12	0.051	4.2	8.2	2.0	1	23	394	417	394	417	0.97
8	12	0.01	0.86	10.4	4.0	1	23	423	445	423	445	0.96
9	12	0.00088	0.073	13.7	2.9	2	23	452	473	451	473	0.96
10	12	0.00011	0.0093	16.6	1.2	3	23	563	584	561	584	0.95
11	12	0.0031	0.25	12.0	1.1	1	19	590	608	590	612	0.95
12	12	4.1e-06	0.00034	21.1	1.0	1	23	618	640	618	640	0.98

Sequence Information

Coding Sequence: ATGGATATGGTTGCAAGAGAGCCATATCCGGTCAACTCAATATGTCGCCTCTGTCTCATGTACCTGGACTCTGGGCTCTGCCCCTCTCACGATCTATATCTGGAGCCAGATCTGGCCAAAAAGCTAATCCTTTGCACAACCCTCGATGTGGACCAGCAGGATGGGTTTCCCCGGAGCATCTGCAATGGATGCTTTGGGAAATTGAACGAGTTGCAAGAGTTTCAAAAACTATGCCTGGACTCTGTGCAGCGTTTCAAGGAAATGGTGGCCGCCAACAGAATCATCACAATCGAATTATTAGAGCCGGTGGCGGAACAGGCAGCGGAGGTGATTGTAGGCCCGGAGGAGCAGGCTAGCTATGATCCCCTGCTTAATCATAAGCTGGAGATGTTTGAGAACGAGGACGAGGTTTTCAAGATGCTGGTGACTGTGGACAAGAGCGTTTTCTCCGACTACACATCCGATGAGAACGACGatgaggagaaggaggaggagaaggatgGCGAAGAAAAGAGCTCCACTGATGACGATCTTCCATTGGCTCATCGATTACAGGGCGAAGAAGAGAAGACCTCCAACGAACGGGCAAAGCGAAAAAAGATTCCACCTGCTGAGCGTCGCCTTCGCCGTATCATCACCTGCACCATCTGCCAGCAAAAGTTCAAAAAGCAGTCGAAATTCGAGGAGCATATGAAGTATCACAACGACCTCCTGCCCTTCCAGTGTAAAGAGGAGACCTGCAAGAAGGGCTTCACCACAGCCGGCGCACTGCGTCTCCATGTGGACTATGCGCACACCAGGAAAGCCGATGAGATACCGTGCACCGTGGAGGGGTGTAAGTTTCTGTTTCCCCGCCTGAGGCTGCTCACCATTCACCTGAAGAAGGTCCACAACCAGACGCGAGTGAGTGTCCCGCGAGCGGAGCAGCCTTGCGGCGAGTGTGGCATGGTCTTCCGCTGTCAGGTGGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGGAGTTGCCCTACCCTTGCAACATCTGCGGCAAGGGATTCCACATCAACAGCGCCCTCAAGAACCATCTGCTGCGGCATGCGGGCATCAAGAACTACGTCTGTCCGTATTGCGGCGTGGGCAAGACCACGCGCCAGGAGTGGAGCAAGCACATGCTGACCCACACCCAGGAAAAGCAGTTCAAGTGTGCCACCTGCGACCATGCCACGCACACAAAGCGAGCGCTCGACAATCATGTGAAGATCGTCCACGAAAAGGTGCGAAATTTTGCCTGCCAGTACTGCGGGAAGACGTTCGGCAAGTCGCATGCCTGCAAAATCCATGAGATGACACACACGGGGGAGAAGCGGTGCGAGTGCAAGGTATGCGGAAAGAAGTTCCTGTACACCGAGAGCCTCACAAAACACCTGAAGATACACGAGAAGAGCGTGGAGCGAGCCTTGGAGACGTATCGCCAGCGGCAGGGAGAGACCACTGCCGACCAGGACCAGCCCCAAGTGGATGCCAATCACCTGATGAAAGTCTGCGCCGAATCGGTAGCCACAATTCCTCGGGATCCGCGCCGCGTTGAACGCGTTGATATGGCCCAATTAGCGGGCACTGTGGTGAATCCCATTCCCACCGTTTCACTGCCCTCTAGTGCGCCGCCCCAAGCAAAGTTTGTCCAGAAGGAAGGCATGCATCTGTGCCCGGGATGCAACCAGGGATTCAACAATCTGGGGAACATGAAGCGACACTACAAAAGCATCCACGAGAAGGTCAAAGACTTTGAGTGCCGCTTCTGTTCGCGTCGCTTCGCCAACTCGCAGTCGCTCAAGCAGCACGAGTGGATACACACGGGGGAGAAGCCCTACGCCTGCAAGACCTGTGGTACCCACTTCCGCCAGGAGGCGGCACTCATCCGCCACCAAAAGGTGCACGACGAAAAGCAACCCAGGCCGGCAAAACCGCCTAAGGAAATCACAGACAAGGCACGCCAGAAGCTGCTGCAGAGGTGCGAGCGGAAGCGCAAGGTGGAGGCACTACGTCAGGAGATAGCCCAGGCTGCCAAGGAGGAGCTGAAGGACTTGGAAAAGCAGCGAGCCCTGGAGATGGAGCAGAATACCTATGAAAAGTATCAGGCAGCTGCAGAGGCGGTGGGTACCACCTCAACTGAAAGTTGA
Protein Sequence: MDMVAREPYPVNSICRLCLMYLDSGLCPSHDLYLEPDLAKKLILCTTLDVDQQDGFPRSICNGCFGKLNELQEFQKLCLDSVQRFKEMVAANRIITIELLEPVAEQAAEVIVGPEEQASYDPLLNHKLEMFENEDEVFKMLVTVDKSVFSDYTSDENDDEEKEEEKDGEEKSSTDDDLPLAHRLQGEEEKTSNERAKRKKIPPAERRLRRIITCTICQQKFKKQSKFEEHMKYHNDLLPFQCKEETCKKGFTTAGALRLHVDYAHTRKADEIPCTVEGCKFLFPRLRLLTIHLKKVHNQTRVSVPRAEQPCGECGMVFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCATCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETTADQDQPQVDANHLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPIPTVSLPSSAPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDEKQPRPAKPPKEITDKARQKLLQRCERKRKVEALRQEIAQAAKEELKDLEKQRALEMEQNTYEKYQAAAEAVGTTSTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536218;
90% Identity: iTF_00601216;
80% Identity: -