Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: ken1
Assembly: GCA_009870125.2
Location: CM020872.1:67015637-67017843[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00014 0.011 16.4 1.0 2 23 204 225 203 225 0.96

2 12 0.0018 0.14 12.8 0.1 1 23 231 256 231 256 0.93

3 12 0.059 4.5 8.1 0.1 3 23 265 288 263 288 0.93

4 12 0.0008 0.061 14.0 0.9 2 23 301 322 300 322 0.96

5 12 1e-05 0.00078 19.9 0.6 1 23 329 351 329 351 0.98

6 12 0.0026 0.2 12.4 0.2 1 23 357 379 357 379 0.98

7 12 0.054 4.1 8.2 2.0 1 23 385 408 385 408 0.97

8 12 0.011 0.84 10.4 4.0 1 23 414 436 414 436 0.96

9 12 0.00093 0.071 13.8 2.9 2 23 443 464 442 464 0.96

10 12 0.00012 0.009 16.6 1.2 3 23 554 575 552 575 0.95

11 12 0.0033 0.25 12.1 1.1 1 19 581 599 581 603 0.95

12 12 4.4e-06 0.00033 21.1 1.0 1 23 609 631 609 631 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00014	0.011	16.4	1.0	2	23	204	225	203	225	0.96
2	12	0.0018	0.14	12.8	0.1	1	23	231	256	231	256	0.93
3	12	0.059	4.5	8.1	0.1	3	23	265	288	263	288	0.93
4	12	0.0008	0.061	14.0	0.9	2	23	301	322	300	322	0.96
5	12	1e-05	0.00078	19.9	0.6	1	23	329	351	329	351	0.98
6	12	0.0026	0.2	12.4	0.2	1	23	357	379	357	379	0.98
7	12	0.054	4.1	8.2	2.0	1	23	385	408	385	408	0.97
8	12	0.011	0.84	10.4	4.0	1	23	414	436	414	436	0.96
9	12	0.00093	0.071	13.8	2.9	2	23	443	464	442	464	0.96
10	12	0.00012	0.009	16.6	1.2	3	23	554	575	552	575	0.95
11	12	0.0033	0.25	12.1	1.1	1	19	581	599	581	603	0.95
12	12	4.4e-06	0.00033	21.1	1.0	1	23	609	631	609	631	0.98

Sequence Information

Coding Sequence: ATGGATATGGTTGCAAGCGAACCATATCCCGCCAACTCAATATGCCGCCTTTGTCTGATGTACCTGGACCAGAGCCCCGCCCACGATCTCTATCTGGAGCCAGATCTGGCCAAAAAGCTAACCCTCTGCACCACCCTCGATGTGGATCAGCAGGATGGCTTTCCCCGGAGAATCTGCCATGGATGCTTTGGGAAATTGAACGAGTTGCAAGAGTTTCAAAAACTATGCCTGGACTCTGTGCAGCGATTCAAGGAAATGGTGGCCGCCAACAGAATCATCACCATCGAATTGTTGGAGCCGGTGGCGGAACAGGCAGCGGAAGTGATTGTAGGGCCGGAGGAGCAGGCTAGCTATGATCCACTGCTAAATCATAAGCTGGAGATTATTGAGAACGAGGAGGAGGTTTTCAAGATGCTGGTGACTGTGGACAAGAACGTTTTCTCCGACTACACATCCGATGAGGAGCCGGAAGATGGCGAAGagaagagctccactgatgaCGAACTTCCATTGGCCCGTCGTTTgctgggagagggagaggagacGGCCAATGAACGGGCAAAGCGAAAAAAGATTCCACCTGCCGAGCGTCGCCTCCGTCGTATCATCCCCTGCACCATTTGCCCGCAAAAGTTCAAAAAGCAATCGAAATTCGACGAGCACATGAAGTATCACAACGACCTCCTGCCCTTCCAGTGCACAGAGGAGACCTGCCGAAAAGGATTCACCACAGCCGGCGCACTGCGTCTCCATGTGGACTATGCGCACACTAGGAAAGCGGATGAGATACCCTGCACCGTGGAAGGGTGCAAGTTTCTGTTTCcccggctgcggctgctcaCCATTCACTTGAAGAAGGTCCACAACCAGACTCGGGTGAGTGCTCCGCGAGCGGAGCAGCCGTGCGGCGAGTGTGGCATGGTCTTCCGCTGTCAGGTGGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGAAGTTGCCCTACCCTTGCAACATCTGCGGCAAGGGATTCCACATCAACAGCGCTCTCAAGAACCATCTACTGCGGCATGCGGGCATCAAGAACTACGTCTGTCCGTACTGCGGCGTGGGCAAGACGACACGACAGGAGTGGAGCAAGCACATGCTGACACACACCCAGGAAAAGCAGTTCAAGTGTGCCACCTGCGACCATGCCACGCACACAAAGCGTGCGCTCGACAATCATGTGAAGATCGTCCACGAGAAGGTCCGAAACTTTGCCTGCCAGTACTGCGGGAAGACGTTCGGCAAGTCGCACGCCTGCAAAATCCATGAGATGACACACACGGGGGAGAAGCGGTGTGAGTGCAAGGTCTGCGGAAAGAAGTTCCTGTACACCGAGAGCCTCACAAAGCACCTGAAGATACACGAGAAGAGCGTGGAGCGAGCCCTGGAGACGTATCGTCAGCGGCAGGGAGAGACCTCTGccgaccaggaccaggcccaaGTGGATGCCAATCACCTGATGAAAGTCTGCGCGGAATCGGTGGCCACAATCCCTCGGGATCCGCGACGCGTTGAACGTGTTGATATGGCCCAATTAGCGGGCACAGTGGTTAATCCCATCCCCAGCGTATCGCTGCCCTCCAGTGCGCCGCCCCAGGCAAAGTTTGTCCAGAAGGAGGGCATGCATCTGTGCCCGGGGTGTAATCAGGGATTCAATAATCTGGGGAACATGAAGCGACACTACAAGAGCATCCACGAGAAGGTCAAGGACTTCGAGTGCCGCTTCTGTTCGCGACGCTTCGCCAACTCGCAGTCGCTCAAGCAGCACGAGTGGATACACACGGGGGAGAAGCCCTACGCCTGCAAAACCTGTGGCACCCACTTCCGCCAGGAGGCGGCTCTCATCCGCCACCAAAAGGTGCACGACGAAAAGCCACCCAGGCCGGCGAAACCCCCTAAGGAAATCACAGACAAGGCACGCCAGAAGCTGCTCCAGAGGTGCGAGCGCAAGCGCAAGGTGGAGGCACTGCGTCAGGAGATAGCCCAGGCCGCCAAGGAGGAGCTGAAGGACTTGGAAAAGCAGCGAGCCCTCGAGAAGGAGCAGAATACCTACGAAAAGTATCAGGCAGCTGCCGAGGCGGTGGCCACCACCCCAACTGGCAGTTGA
Protein Sequence: MDMVASEPYPANSICRLCLMYLDQSPAHDLYLEPDLAKKLTLCTTLDVDQQDGFPRRICHGCFGKLNELQEFQKLCLDSVQRFKEMVAANRIITIELLEPVAEQAAEVIVGPEEQASYDPLLNHKLEIIENEEEVFKMLVTVDKNVFSDYTSDEEPEDGEEKSSTDDELPLARRLLGEGEETANERAKRKKIPPAERRLRRIIPCTICPQKFKKQSKFDEHMKYHNDLLPFQCTEETCRKGFTTAGALRLHVDYAHTRKADEIPCTVEGCKFLFPRLRLLTIHLKKVHNQTRVSAPRAEQPCGECGMVFRCQVALKKHMYKHTGEKLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCATCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETSADQDQAQVDANHLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPIPSVSLPSSAPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDEKPPRPAKPPKEITDKARQKLLQRCERKRKVEALRQEIAQAAKEELKDLEKQRALEKEQNTYEKYQAAAEAVATTPTGS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536218;
90% Identity: iTF_00601216;
80% Identity: -