Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: ken1
Assembly: GCA_035043285.1
Location: JAWNNB010001571.1:2869756-2871970[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00075 0.054 14.1 2.6 2 23 208 229 207 229 0.97

2 12 0.00082 0.059 14.0 0.2 1 23 235 260 235 260 0.93

3 12 0.064 4.6 8.0 0.1 3 23 269 292 267 292 0.92

4 12 0.002 0.15 12.7 1.2 2 23 305 326 304 326 0.96

5 12 1e-05 0.00075 19.9 0.6 1 23 333 355 333 355 0.98

6 12 0.0026 0.19 12.4 0.2 1 23 361 383 361 383 0.98

7 12 0.055 4 8.2 2.0 1 23 389 412 389 412 0.97

8 12 0.011 0.81 10.4 4.0 1 23 418 440 418 440 0.96

9 12 0.00095 0.068 13.8 2.9 2 23 447 468 446 468 0.96

10 12 0.00012 0.0087 16.6 1.2 3 23 558 579 556 579 0.95

11 12 0.0033 0.24 12.0 1.1 1 19 585 603 585 607 0.95

12 12 4.5e-06 0.00032 21.1 1.0 1 23 613 635 613 635 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00075	0.054	14.1	2.6	2	23	208	229	207	229	0.97
2	12	0.00082	0.059	14.0	0.2	1	23	235	260	235	260	0.93
3	12	0.064	4.6	8.0	0.1	3	23	269	292	267	292	0.92
4	12	0.002	0.15	12.7	1.2	2	23	305	326	304	326	0.96
5	12	1e-05	0.00075	19.9	0.6	1	23	333	355	333	355	0.98
6	12	0.0026	0.19	12.4	0.2	1	23	361	383	361	383	0.98
7	12	0.055	4	8.2	2.0	1	23	389	412	389	412	0.97
8	12	0.011	0.81	10.4	4.0	1	23	418	440	418	440	0.96
9	12	0.00095	0.068	13.8	2.9	2	23	447	468	446	468	0.96
10	12	0.00012	0.0087	16.6	1.2	3	23	558	579	556	579	0.95
11	12	0.0033	0.24	12.0	1.1	1	19	585	603	585	607	0.95
12	12	4.5e-06	0.00032	21.1	1.0	1	23	613	635	613	635	0.98

Sequence Information

Coding Sequence: ATGGTTGCGAGCGAGCCATATCCCGTCCACTCAATATGCCGCCTCTGTCTGATGTACCTGAAGCAGGGCACCGCCCACGATCTGTTTCTGGAGCCAGATCTGGCCAAAAAGCTAACCCTGTGCACCTCCCTAGATGTGGACCAGCAGGATGGCTATCCACGGAGCATCTGCAACGGATGCTTTGGGAAATTGAACAACTTGCAGGAGTTTCAAAAACTATGCCTGGACTCTGTGCAGCGATTCAAGGATATGGTGGCTGCCAATAGAATCGTCACAGTCGAATTGTTGGAGCCGGTGGCCGAACAGCCAGCGGAGGTGATTGTAGGGCCGGAGGAGCAGGCCAGCTATGATCCGCTGCTAAATCACAAGCTGGAGATGATTGAGAACGAGGAGGAGGTCTTCAAGATGCTGGAGCATGTGGACAAGGAGGCCGAGGAGGCGGAGAAGGAGGTCAAGGTTTTCTCCGACCACACATCCGAGGAGAACGATGACGAGGAGGATGATGGCTCCACCGATGACGAACTTCCATTGGCGCATCGTTTGCTGGGTGAGGAGACGGCCAAGGAGCGGGCCAAGCGGAAAAGGATTCCACCTGAGGAGCGTCGCCTTCGCCGTATCATCACCTGCACCGTCTGCCAGCAAAAGTTCAAGAAACAATCAAAATTTGACGAGCACATGAAGTACCACAACGACCTCCTGCCCTTCCAGTGCACAGAGGAGACCTGCAAGAAGGGCTTCACCACAGCCGGTGCACTGCGTCTGCATGTGGACTATGCGCACACCAGGAAAGCCGAAGAGATACCCTGCAGCGTGGAGGGCTGCAAGCTGCTGTTTCCCCGCCTGCGGCTGCTCACCATTCACCTGAAGAAGGTGCACAACCAGACGCGGGTGAGCGCACCGCGAGCGGAGCAGCCGTGCATGGAATGTGGCATGGTCTTCCGCTGTCAGGTGGCCCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCGTATCCGTGCAACATCTGCGGCAAGGGATTCCACATCAACAGCGCCCTCAAGAACCATCTGCTGCGGCATGCGGGCATCAAGAACTACGTCTGCCCGTACTGTGGCGTGGGCAAGACGACGCGTCAGGAGTGGAGCAAGCACATGCTGACCCACACCCAGGAGAAGCAGTTCAAGTGCGCCACCTGCGACCATGCCACGCACACAAAGCGAGCGCTCGACAATCATGTGAAGATCGTTCACGAGAAGGTCCGAAACTTTGCCTGCCAGTACTGCGGCAAGACGTTCGGCAAGTCGCATGCCTGCAAGATCCACGAGATGACGCACACGGGGGAGAAGCGCTGCGAATGCAAgGTCTGTGGCAAGAAGTTCCTGTACACCGAAAGCCTCACGAAACACCTGAAGATACACGAGAAGAGCGTGGAGCGTGCCTTGGAGACGTATCGCCAGCGGCAGGGAGAGACCAGCGCCGATCAGGAACAGGTCCAAGTGGATGCCAATCAACTGATGAAAGTCTGCGCCGAATCGGTGGCCACAATACCACGGGATCCGCGACGCGTGGAGCGCGTTGATATGGCCCAATTGGCGGGCACTGTGGTGAATCCTATACCCATTGTGTCGCTGCCCTCCAATGCGCCGCCCCAGGCAAAGTTCGTCCAGAAGGAGGGCATGCATCTGTGCCCGGGCTGCAATCAGGGATTCAACAATCTGGGCAACATGAAGCGACACTACAAGAGCATCCACGAGAAGGTCAAAGACTTTGAGTGCCGCTTCTGTTCGCGTCGCTTCGCCAACTCGCAGTCGCTCAAGCAGCACGAATGGATACACACGGGCGAGAAGCCCTACGCCTGCAAGACCTGCGGCACCCACTTCCGCCAGGAGGCGGCTCTCATACGCCACCAAAAGGTGCACGACGTGAAGCCACCCCGGCCAGCGAAAGCGCCCAAGGAAATCACAGACAAGGCGCGCCAGAAGCTGCTTCAGAGATGCGAACGCAAGCGCAAGGTGGAGGCACTGCGCCAGGAGATAGCCCAGGCCGCCAAGGAGGAGCTGAGGGACTTGGAAAAGCAGCGGGCCctggagaagcagcagaataCCTACGAAAAGTatcaggcagcggcagaggcggTGGAGAGCACTTCGACTTGA
Protein Sequence: MVASEPYPVHSICRLCLMYLKQGTAHDLFLEPDLAKKLTLCTSLDVDQQDGYPRSICNGCFGKLNNLQEFQKLCLDSVQRFKDMVAANRIVTVELLEPVAEQPAEVIVGPEEQASYDPLLNHKLEMIENEEEVFKMLEHVDKEAEEAEKEVKVFSDHTSEENDDEEDDGSTDDELPLAHRLLGEETAKERAKRKRIPPEERRLRRIITCTVCQQKFKKQSKFDEHMKYHNDLLPFQCTEETCKKGFTTAGALRLHVDYAHTRKAEEIPCSVEGCKLLFPRLRLLTIHLKKVHNQTRVSAPRAEQPCMECGMVFRCQVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHMLTHTQEKQFKCATCDHATHTKRALDNHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGETSADQEQVQVDANQLMKVCAESVATIPRDPRRVERVDMAQLAGTVVNPIPIVSLPSNAPPQAKFVQKEGMHLCPGCNQGFNNLGNMKRHYKSIHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHDVKPPRPAKAPKEITDKARQKLLQRCERKRKVEALRQEIAQAAKEELRDLEKQRALEKQQNTYEKYQAAAEAVESTST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536218;
90% Identity: iTF_00601216;
80% Identity: -