Doch001048.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ochracea
Gene Symbol
-
Assembly
GCA_035044125.1
Location
JAWNML010000003.1:8587320-8590793[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0004 0.025 14.9 2.2 1 23 214 237 214 237 0.97
2 12 1.4e-05 0.00087 19.5 2.4 1 23 242 265 242 265 0.96
3 12 0.00043 0.027 14.8 4.5 1 23 270 292 270 292 0.98
4 12 5.9 3.7e+02 1.8 5.8 2 23 299 322 298 322 0.90
5 12 0.00019 0.012 15.9 1.5 3 23 332 353 331 353 0.95
6 12 0.0034 0.22 12.0 0.1 1 23 359 382 359 382 0.95
7 12 0.33 21 5.8 0.2 5 23 398 417 393 417 0.87
8 12 3.1e-05 0.0019 18.4 0.4 1 23 446 468 446 468 0.98
9 12 1.5e-05 0.00093 19.4 5.3 1 23 474 496 474 496 0.96
10 12 3.8e-06 0.00024 21.3 0.2 2 23 503 524 503 524 0.97
11 12 0.00075 0.047 14.1 1.5 1 23 531 553 531 553 0.99
12 12 6.5e-05 0.0041 17.4 3.0 1 23 559 582 559 582 0.98

Sequence Information

Coding Sequence
ATGGAAACGTGTCGCACTTGTGCTAGGTGCGATTTcgaaaatggcaacaacaactattggTTGGACTTGTTCCATCCAACGAGTTGGCAGAACGAAATGGCGCAAATACGCCTCGAGTTTGCCAACTGGAAGTTACAGatctCACCTAACGATGGActgccacaaaaaatatgtagcGATTGTTTTACAAAATTCTGCTCCATTTACACGTTTCGCATGGCTTGCCAGGATGCGCAATTGAAGCTCtcgaatatttttgataaaatcGATGCCCATATGCTGTATGACAAAAACGACGAAGCGGAGCCCATTGCAGATGATGCAGATGAAATAGAAACCTCGACAGAAGCACACAGAAACATAgaagcaataacaacgacaaaagcaacacaagACACTGCCATTATTGAGGCCACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAACATCAACGAAGTAGAAGATATATCCCCACAGCCAGTAATAGACGAGCAAACCGATTTGGCTTCAGACTACAGCACATTAAAAATTAGCTATGCTTGCAAATTTTGTTACAAGCCACAGGCGGGCTATGAACTGCAGCATGTGCTTCTAGAGCACATTAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCACATTGCACAGAATGCTTCCAGGACGCTGCCTCCCGCACCGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACGCGTGCGAGGTGTGCGGCAAAAAGTATGGAGATCGTCATAATCTTCAGCATCACATCGAGAAATATCATTCAGAAACGGATTTCGAGTGCAGCTTGTGTGAGAAGCGTTTCTTTACACGCAAAAGCCTTCATTACCACATGAACTGGCACAAGCCAGAGAGGCAGCTGAGGTGTCGCCACACTGGCTGCGACAGGCTCTTCATCAATCAACGACATCTCAAATGCCATGAGGCAACTCACACAACCGGCTCTCGCAAGAGTGAATACTGCGGTTTCTGTGGCAAAGCTTTCACACATGTTAAAACACTACGATGGCATATCTATAGACAGCATGGCGGTGAGAAGCCCTTCAAATGTGCCATTTGCACTGAGGtttttgaCTCGTATGCTGAGAAGCGTATTCACATGCTCGAGTTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCCTGTCGCCAGGAGTTCGACACCGAACAGGAGCTCATCCAGCACATGAGCGCCGAGCATCTGCAACGCGAACCGTCAGCTCCAGTGATATCGAACAATAAGCGAGTGCTCCAGCGAAAGCGGGAGCGCCAATATACGGGTCTCTTCCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCACTGGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGTTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCCAATGAGAAGCCCAATGTTTGTGATGTTTGCGGTAAATCATTTGCCCTGAAATATGTACTTACTCAGCATATGCGTAGTCATGAGGttcTTGAGAAGAACTTCAAGTGTGACACTTGTGGAcgttcttatttatttgagaaGTCCCTGCGTCTCCATCAACGTGTTCACACTGGCAACACTTACTACAAATGCGATTTGTGTCAGGAGCGTTTTGTGACTCacatcaaattgaaaaCTCATATGAAAAAGGCACATGATACAAACCAGTCGCATGCCAAAGATTCGCTGGATAATTTGATCAACATTGTGATTTCCTAA
Protein Sequence
METCRTCARCDFENGNNNYWLDLFHPTSWQNEMAQIRLEFANWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEAEPIADDADEIETSTEAHRNIEAITTTKATQDTAIIEATSPTPIEIYVETININEVEDISPQPVIDEQTDLASDYSTLKISYACKFCYKPQAGYELQHVLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYACEVCGKKYGDRHNLQHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHTGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSAEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKLKTHMKKAHDTNQSHAKDSLDNLINIVIS