Dmim009417.1
Basic Information
- Insect
- Drosophila mimica
- Gene Symbol
- -
- Assembly
- GCA_037043585.1
- Location
- JBAMBE010000661.1:2304880-2308242[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00039 0.026 14.9 2.2 1 23 204 227 204 227 0.97 2 12 1.2e-05 0.00079 19.7 3.3 1 23 232 255 232 255 0.97 3 12 0.00031 0.02 15.3 4.6 1 23 260 282 260 282 0.98 4 12 5.4 3.5e+02 1.9 5.7 2 23 289 312 288 312 0.90 5 12 0.00019 0.012 16.0 1.5 3 23 322 343 321 343 0.95 6 12 0.0034 0.22 12.0 0.1 1 23 349 372 349 372 0.95 7 12 0.32 21 5.8 0.2 5 23 388 407 383 407 0.87 8 12 3e-05 0.002 18.4 0.4 1 23 436 458 436 458 0.98 9 12 1.4e-05 0.00094 19.5 5.3 1 23 464 486 464 486 0.96 10 12 3.7e-06 0.00024 21.3 0.2 2 23 493 514 493 514 0.97 11 12 0.00073 0.047 14.1 1.5 1 23 521 543 521 543 0.99 12 12 0.00035 0.022 15.1 3.9 1 23 549 572 549 572 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACTTGTGCAAGATGCGATTtcgaaaatggcaacaactatTGGCTGGACTTGTTCCATCCAACGAGTTGGCAGAACGAAATGGCGCAAATACGCCTAGAGTTTGTCAACTGGAAATTACAGatCTCACCTAACGATGGactgccacaaaaaatatgtagcgATTGTTTTACAAAATTCTGCTCTATTTACACGTTTCGCATGGCCTGCCAGGATGCGCAATTGAAGCTCTcgaatatttttgataaaatcGATGCTCATATGCTGTATGACAAGAACGACGAAGAGGAGCACATTGTGGATGTGGCAAGCCAAATAGAAACGTCAACGGAAACAGAAGCAATAACAACGAGAAAAGAAACACAAGACACTGCCATTATTGAGGACACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAGCATCAACGAAATAGATAAATCCCCACAGCCAGTAGTAGACGAGCAAACCGATTACAGCACATTGAACATTAGCTATGCTTGCAAATTTTGCTACAAGCCACAGGCGAGCTATGAACTGCAGCATATGCTCCTAGAGCACATAAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCGCATTGCACAGAATGTTTCCAAGATGCTGCATCCCGCACCGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACTCCTGCGAGGTGTGCGGCAAAAAGTATGGAGATCGACACAATCTTCAGCATCACATTGAGAAATATCACTCGGAAACGGATTTCGAGTGCAGCATGTGTGAGAAGCGTTTCTTTACACGCAAAAGCCTCCATTACCACATGAACTGGCACAAGCCAGAGAGGCAGCTGCGATGTCGTCACAGTGGCTGCGACAGGCTCTTCATCAATCAACGACATCTCAAATGCCACGAGGCAACTCACACAACCGGCTCTCGTAAGAGTGAATACTGCGGTTTTTGTGGCAAAGCTTTCACACATGTTAAAACCCTAAGATGGCATATCTATAGACAGCATGGCGGTGAGAAGCCCTTCAAATGTGCAATTTGCACTGAGGTTTTTGACTCGTATGCTGAAAAGCGTATTCACATGCTCGAATTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCATGTCGCCAGGAGTTCGATACCGAACAGGAGCTCATCCAGCACATGAGCGCCGAGCATCTTCAACGCGAACCGTCAGCTCCAGTTATTTCGAACAATAAGCGAGTACTCCAACGGAAACGGGAGCGCCAATATACTGGTCTCTTCCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCACTAGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGTTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCCAATGAAAAGCCCAATGTTTGTGATGTTTGCGGAAAGTCATTTGCCCTGAAATATGTACTTACCCAGCATATGCGCAGTCATGAGGttcTCGAGAAGAACTTCAAATGTGACACCTGTGGACGTTCTTATCTATTTGAGAAGTCTCTGCGTCTGCATCAACGTGTCCACACGGGCAACACTTACTACAAATGCGATTTGTGCCAGGAACGCTTTGTGACACacatcaaatttaaaaCTCATATGAAAAAGGCACATGATACAAACCAGTCTCATGCCAAAGATTCGCTGGATAATTTGATCAATATTGTGATTTCCTAA
- Protein Sequence
- METCRTCARCDFENGNNYWLDLFHPTSWQNEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEEEHIVDVASQIETSTETEAITTRKETQDTAIIEDTSPTPIEIYVETISINEIDKSPQPVVDEQTDYSTLNISYACKFCYKPQASYELQHMLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYSCEVCGKKYGDRHNLQHHIEKYHSETDFECSMCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSAEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKAHDTNQSHAKDSLDNLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00564814;
- 80% Identity
- -