Dspr010824.1
Basic Information
- Insect
- Drosophila sproati
- Gene Symbol
- -
- Assembly
- GCA_018904355.1
- Location
- JAEIFY010000003.1:296534-300290[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 8.8 5.9e+02 1.0 1.9 3 16 58 71 57 73 0.84 2 13 0.00034 0.023 14.9 2.2 1 23 210 233 210 233 0.97 3 13 1.2e-05 0.00079 19.5 2.4 1 23 238 261 238 261 0.96 4 13 0.00027 0.018 15.2 4.6 1 23 266 288 266 288 0.98 5 13 4.6 3.1e+02 1.9 5.7 2 23 295 318 294 318 0.90 6 13 0.00016 0.011 15.9 1.5 3 23 328 349 327 349 0.95 7 13 0.0029 0.2 12.0 0.1 1 23 355 378 355 378 0.95 8 13 0.28 19 5.8 0.2 5 23 394 413 389 413 0.87 9 13 2.6e-05 0.0017 18.4 0.4 1 23 442 464 442 464 0.98 10 13 1.2e-05 0.00083 19.4 5.3 1 23 470 492 470 492 0.96 11 13 3.2e-06 0.00022 21.3 0.2 2 23 499 520 499 520 0.97 12 13 0.00063 0.042 14.1 1.5 1 23 527 549 527 549 0.99 13 13 5.5e-05 0.0037 17.4 3.0 1 23 555 578 555 578 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACTTGTGCTAGGTGCGATTTCGAAAATGGCAACAACAACTATTGGTTGGACTTGTTCCATCCAACGAGTTGGCAGAACGAAATGGCGCAAATACGCCTCGAGTTTGCCAACTGGAAGTTACAGATCTCACCTAACGATGGACTGCCACAAAAAATATGTAGCGATTGTTTTACAAAATTCTGCTCCATTTACACGTTTCGCATGGCTTGCCAGGATGCGCAATTGAAGCTCTCGAATATTTTTGATAAAATCGATGCCCATATGCTGTATGACAAAAACGACGAAGCGGAGCCCATTGCAGATGATGCAGATGAAATAGAAACGTCAACAGAAATAGAAGCAATAACAACGACAAAAGCAACACAAGACACTGCCATTATTGAGGCCACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAACATCAACGAAGTAGAAGATATATCCCCACAGCCAGTAGTAGACGAGCAAACCGATTTCGCTTCAGACTACAGCACATTGAACATTAGCTATGCTTGCAAATTTTGTTACAAGCCACAGGCGAGCTATGAACTGCAGCATGTACTTCTAGAGCACATTAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCGCATTGCACAGAATGCTTCCAGGACGCTGCCTCCCGCACCGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACGCGTGCGAGGTGTGCGGCAAAAAGTATGGAGATCGTCATAATCTTCAGCATCACATCGAGAAATATCATTCAGAAACGGATTTCGAGTGCAGCATGTGTGAGAAGCGATTCTTTACACGCAAAAGCCTTCATTACCACATGAACTGGCACAAGCCAGAGAGGCAGCTGAGGTGTCGCCACAGTGGCTGCGACAGGCTCTTCATTAATCAACGACATCTCAAATGCCATGAGGCAACTCACACAGCCGGCTCTCGCAAGAGTGAATACTGCGGTTTCTGTGGCAAAGCTTTCACACATGTTAAAACACTACGATGGCATATCTATAGACAGCATGGCGGTGAGAAGCCTTTCAAATGTGCCATTTGCACTGAGGTTTTTGACTCGTATGCTGAAAAGCGTATTCACATGCTCGAGTTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCCTGTCGCCAGGAGTTCGACACCGAACAGGAGCTCATCCAGCACATGAGCGCCGAGCATCTGCAACGCGAACCGTCAGCTCCAGTGATATCGAACAATAAGCGAGTGCTCCAGCGGAAACGGGAGCGCCAATATACGGGTCTCTTCCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCATTGGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGTTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCCAATGAGAAGCCCAATGTTTGTGATGTTTGCGGTAAATCATTTGCCCTGAAATATGTACTTACTCAGCATATGCGCAGTCATGAGGTTCTTGAGAAGAACTTCAAGTGTGACACTTGTGGACGTTCTTATCTATTTGAGAAGTCTCTGCGTCTCCATCAACGGGTTCACACTGGCAACACTTACTACAAATGCGATTTGTGTCAGGAGCGTTTTGTGACTCACATCAAATTGAAAACTCATATGAAAAAGGCACATGATACAAACCAGTCGCATGCCAAAGATTCGCTGGATAATTTGATCAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCARCDFENGNNNYWLDLFHPTSWQNEMAQIRLEFANWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEAEPIADDADEIETSTEIEAITTTKATQDTAIIEATSPTPIEIYVETININEVEDISPQPVVDEQTDFASDYSTLNISYACKFCYKPQASYELQHVLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYACEVCGKKYGDRHNLQHHIEKYHSETDFECSMCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTAGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSAEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKLKTHMKKAHDTNQSHAKDSLDNLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00564814;
- 80% Identity
- -