Dcon011937.1
Basic Information
- Insect
- Drosophila conformis
- Gene Symbol
- -
- Assembly
- GCA_035041375.1
- Location
- JAWNLE010000868.1:1410730-1414133[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00042 0.027 14.9 2.2 1 23 205 228 205 228 0.97 2 12 7.2e-06 0.00047 20.5 2.8 1 23 233 256 233 256 0.97 3 12 0.00045 0.029 14.8 4.5 1 23 261 283 261 283 0.98 4 12 5.7 3.7e+02 1.9 5.7 2 23 290 313 289 313 0.90 5 12 0.0002 0.013 15.9 1.5 3 23 323 344 322 344 0.95 6 12 0.0036 0.23 12.0 0.1 1 23 350 373 350 373 0.95 7 12 0.14 9.3 7.0 0.2 5 23 389 408 384 408 0.89 8 12 3.2e-05 0.0021 18.4 0.4 1 23 437 459 437 459 0.98 9 12 1.5e-05 0.001 19.5 5.3 1 23 465 487 465 487 0.96 10 12 4e-06 0.00026 21.3 0.2 2 23 494 515 494 515 0.97 11 12 0.00078 0.051 14.1 1.5 1 23 522 544 522 544 0.99 12 12 0.00037 0.024 15.1 3.9 1 23 550 573 550 573 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACTTGTGCAAGATGCGATTtcgaaaatggcaacaacaactattggCTGGACTTGTTCCACCCAACGAGTTGGCAGAACGAAATGGCGCAAATACGCCCCGAGTTTGTCAACTGGAAGTTACAGatCTCACCTAACGATGGACtgccacaaaaaatatgtagcGATTGTTTTACAAAATTCTGCTCCATTTACACGTTTCGCATGGCCTGCCAGGATGCGCAATTGAAGCTCTcgaatatttttgataaaatCGATGCCCATATGCTGTATGACAAGAACGATGAAGAGGAGCACATTGCTGATGATGCAAATGAAATAGAAACGTCAACGGAAatagaagcaacaacaacgacaaaagcaacacaagaCACTGCCATTATTGAGGCCACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAACATCAACGAAATAGACCAAGTAGTAGACGAGCAAACCGATTTGACTTCAGATTATAGCACATTGAACATTAGCTATGCTTGCAAATTTTGTTACAAGCCACAAGCGAGCTATGAACTGCAGCATATGCTCCTAGAGCACATTAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCGCATTGCACTGAATGCTTCCAGGACGCTGCCTCCCGCACCGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACGAATGCGAGGTGTGCGGCAAAAAGTATGGAGATCGTCATAATCTTCAGCATCACATCGAGAAATATCACTCGGAAACTGATTTCGAGTGCAGCTTGTGTGAGAAGCGTTTCTTTACACGCAAAAGCCTCCATTACCACATGAACTGGCACAAGCCAGAGCGGCAGCTGCGATGTCGCCACAGTGGCTGCGACAGGCTATTCATCAATCAACGACATCTCAAATGCCATGAGGCAACTCACACAACCGGCTCCCGCAAGAGTGAATACTGCGGTTTCTGTGGCAAAGCTTTCACACATGTTAAAACCCTACGatggcatatatatagacagcATGGTGGTGAGAAGCCCTTCAAATGTGCCATTTGCACTGAGGtttttgacTCGTATGCGGAAAAGCGTATTCACATGCTCGAGTTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCCTGTCGCCAGGAGTTTGACACCGAACAGGAGCTCATCCAGCACATGAGCGTCGAGCATCTCCAACGCGAACCGTCTGCTCCAGTTATTTCGAATAATAAGCGAGTGCTCCAGCGGAAACGGGAGCGCCAATATACGGGTCTCTTTCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCACTAGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGCTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCTAATGAGAAGCCCAATGTTTGTGATGTTTGCGGCAAGTCATTTGCCCTGAAATATGTACTTACCCAGCATATGCGCAGTCATGAGGttcTCGAGAAGAACTTCAAGTGTGACACCTGTGGACGTTCTTATCTATTTGAGAAGTCTCTGCGTCTCCATCAACGTGTCCACACGGGCAAGACTTACTACAAATGCGATTTGTGTCAGGAGCGTTTTGTGACTCACATCAAATTTAAAACTCATATGAAAAAGGCGCATGATACAAACCAGCCGCATGCCAAAGATTCGCTGGATAATTTGATCAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCARCDFENGNNNYWLDLFHPTSWQNEMAQIRPEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEEEHIADDANEIETSTEIEATTTTKATQDTAIIEATSPTPIEIYVETININEIDQVVDEQTDLTSDYSTLNISYACKFCYKPQASYELQHMLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYECEVCGKKYGDRHNLQHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSVEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGKTYYKCDLCQERFVTHIKFKTHMKKAHDTNQPHAKDSLDNLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00564814;
- 80% Identity
- -