Basic Information

Insect: Drosophila neutralis
Gene Symbol: -
Assembly: GCA_035044385.1
Location: JAWNME010000532.1:3190131-3193554[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00043 0.029 14.9 2.2 1 23 209 232 209 232 0.97

2 12 7.3e-06 0.0005 20.5 2.8 1 23 237 260 237 260 0.97

3 12 0.00046 0.031 14.8 4.5 1 23 265 287 265 287 0.98

4 12 5.8 4e+02 1.9 5.7 2 23 294 317 293 317 0.90

5 12 0.0002 0.014 15.9 1.5 3 23 327 348 326 348 0.95

6 12 0.0037 0.25 12.0 0.1 1 23 354 377 354 377 0.95

7 12 0.14 9.8 7.0 0.2 5 23 393 412 388 412 0.89

8 12 3.3e-05 0.0022 18.4 0.4 1 23 441 463 441 463 0.98

9 12 1.6e-05 0.0011 19.4 5.3 1 23 469 491 469 491 0.96

10 12 4e-06 0.00028 21.3 0.2 2 23 498 519 498 519 0.97

11 12 0.00079 0.054 14.1 1.5 1 23 526 548 526 548 0.99

12 12 0.0005 0.034 14.7 4.3 1 23 554 577 554 577 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00043	0.029	14.9	2.2	1	23	209	232	209	232	0.97
2	12	7.3e-06	0.0005	20.5	2.8	1	23	237	260	237	260	0.97
3	12	0.00046	0.031	14.8	4.5	1	23	265	287	265	287	0.98
4	12	5.8	4e+02	1.9	5.7	2	23	294	317	293	317	0.90
5	12	0.0002	0.014	15.9	1.5	3	23	327	348	326	348	0.95
6	12	0.0037	0.25	12.0	0.1	1	23	354	377	354	377	0.95
7	12	0.14	9.8	7.0	0.2	5	23	393	412	388	412	0.89
8	12	3.3e-05	0.0022	18.4	0.4	1	23	441	463	441	463	0.98
9	12	1.6e-05	0.0011	19.4	5.3	1	23	469	491	469	491	0.96
10	12	4e-06	0.00028	21.3	0.2	2	23	498	519	498	519	0.97
11	12	0.00079	0.054	14.1	1.5	1	23	526	548	526	548	0.99
12	12	0.0005	0.034	14.7	4.3	1	23	554	577	554	577	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGATGCGATTtcgaaaatggcaacaacaactattggCTGGACTTGTTCCACCCAACGAGTTGGCAGAACGAAATGGCGCAAATCCGCCTCGAGTTTGTCAACTGGAAGTTACAGatctCACCTAACGATGGACtgccacaaaaaatatgtagcGATTGTTTTACAAAATTCTGCTCCATTTACACGTTTCGCATGGCCTGCCAGGATGCGCAATTGAAGCTCTcgaatatttttgataaaatCGATGCCCATATGCTGTATGACAAGAACGATGAAGAGGAGCACATTGCTGATGATGCAAATGAAATAGAAACGTCAACGGAAatagaagcaacaacaacgacaaaagcaacacaagACACTGCCATTATTGAGGCCACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAACATCAACGAAATAGACCAATCCCCACAGCCAGTAGTAGACGAGCAAACCGATTTGACTTCAGATTATAGCACATTGAACATAAGCTATGCTTGCAAATTTTGTTATAAGCCACAAGCGAGCTATGAACTGCAGCATATGCTCCTAGAGCACATTAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCGCATTGCACTGAATGCTTCCAGGACGCTGCCTCCCGCACCGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACGAATGCGAGGTGTGCGGCAAAAAGTATGGAGATCGTCATAATCTTCAGCATCACATCGAGAAATATCACTCGGAAACTGATTTCGAGTGCAGCTTGTGTGAGAAGCGTTTCTTTACACGCAAAAGCCTCCATTACCACATGAACTGGCACAAGCCAGAGCGGCAGCTGCGATGCCGCCACAGTGGCTGCGACAGGCTATTCATCAATCAACGACATCTCAAATGCCATGAGGCAACTCACACAACCGGCTCCCGCAAGAGTGAATACTGCGGTTTCTGTGGCAAAGCTTTCACACATGTTAAAACCCTACGATGGCATATCTATAGACAGCATGGTGGTGAGAAGCCCTTCAAATGTGCCATTTGCACTGAGGtttttgACTCGTATGCGGAAAAGCGTATTCACATGCTCGAGTTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCCTGTCGCCAGGAGTTTGACACCGAACAGGAGCTCATCCAGCACATGAGCGTCGAGCATCTCCAACGCGAACCGTCTGCTCCAGTTATTTCGAATAATAAGCGAGTGCTCCAGCGGAAACGGGAGCGCCAATATACGGGTCTCTTTCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCACTAGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGCTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCTAATGAGAAGCCCAATGTTTGTGATGTTTGCGGCAAGTCATTTGCCCTGAAATATGTACTTACCCAGCATATGCGCAGTCATGAGGttcTCGAGAAGAACTTCAAGTGTGACACCTGTGGACGTTCTTATCTATTTGAGAAGTCTCTGCGCCTCCATCAACGTGTCCACACGGGCAACACTTACTACAAATGCGATTTGTGTCAGGAGCGTTTTGTGACTCACATCAAATTTAAAACTCATATGAAAAAGGAGCACGATACAAATCAGCCGCATGCCAAAGATTCGCTGGATAATTTGATCAACATTGTGATTTCCTAA
Protein Sequence: METCRTCARCDFENGNNNYWLDLFHPTSWQNEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEEEHIADDANEIETSTEIEATTTTKATQDTAIIEATSPTPIEIYVETININEIDQSPQPVVDEQTDLTSDYSTLNISYACKFCYKPQASYELQHMLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYECEVCGKKYGDRHNLQHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSVEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKEHDTNQPHAKDSLDNLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00564814;
80% Identity: iTF_00574235;