Basic Information

Insect: Drosophila percnosoma
Gene Symbol: -
Assembly: GCA_035043855.1
Location: JAWNMQ010000737.1:271739-275165[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00041 0.027 14.9 2.2 1 23 209 232 209 232 0.97

2 12 7e-06 0.00046 20.5 2.8 1 23 237 260 237 260 0.97

3 12 0.00044 0.029 14.8 4.5 1 23 265 287 265 287 0.98

4 12 5.6 3.6e+02 1.9 5.7 2 23 294 317 293 317 0.90

5 12 0.0002 0.013 15.9 1.5 3 23 327 348 326 348 0.95

6 12 0.0035 0.23 12.0 0.1 1 23 354 377 354 377 0.95

7 12 0.14 9.1 7.0 0.2 5 23 393 412 388 412 0.89

8 12 3.1e-05 0.0021 18.4 0.4 1 23 441 463 441 463 0.98

9 12 1.5e-05 0.00098 19.4 5.3 1 23 469 491 469 491 0.96

10 12 3.9e-06 0.00025 21.3 0.2 2 23 498 519 498 519 0.97

11 12 0.00076 0.05 14.1 1.5 1 23 526 548 526 548 0.99

12 12 0.00048 0.031 14.7 4.3 1 23 554 577 554 577 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00041	0.027	14.9	2.2	1	23	209	232	209	232	0.97
2	12	7e-06	0.00046	20.5	2.8	1	23	237	260	237	260	0.97
3	12	0.00044	0.029	14.8	4.5	1	23	265	287	265	287	0.98
4	12	5.6	3.6e+02	1.9	5.7	2	23	294	317	293	317	0.90
5	12	0.0002	0.013	15.9	1.5	3	23	327	348	326	348	0.95
6	12	0.0035	0.23	12.0	0.1	1	23	354	377	354	377	0.95
7	12	0.14	9.1	7.0	0.2	5	23	393	412	388	412	0.89
8	12	3.1e-05	0.0021	18.4	0.4	1	23	441	463	441	463	0.98
9	12	1.5e-05	0.00098	19.4	5.3	1	23	469	491	469	491	0.96
10	12	3.9e-06	0.00025	21.3	0.2	2	23	498	519	498	519	0.97
11	12	0.00076	0.05	14.1	1.5	1	23	526	548	526	548	0.99
12	12	0.00048	0.031	14.7	4.3	1	23	554	577	554	577	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGATGCGATTtcgaaaatggcaacaacaactattggCTGGACTTGTTCCACCCAACGAGTTGGCAGAACGAAATGGCGCAAATACGCCTCGAGTTTGTCAACTGGAAGTTACAGatctCACCTAACGATGGActgccacaaaaaatatgtagcGATTGTTTTACAAAATTCTGCTCCATTTACACGTTTCGCATGGCCTGCCAGGATGCGCAATTGAAGCTCtcgaatatttttgataaaatCGATGCCCATATGCTGTATGACAAGAACGATGAAGAGGAGCACATTGCTGatgatgcaaatgaaataGAAACGTCAACGGAAatagaagcaacaacaacgacaaaagcaacacaagACACTGCCATTATTGAGGCCACATCGCCAACACCCATAGAAATATATGTGGAAACGATAAACATCAACGAAATAGACCAATCCCCACAGCCAGTAGTAGACGAGCAAACCGATTTGACTTCAGATTATAGCACATTGAACATAAGCTATGCTTGCAAATTTTGTTACAAGCCACAAGCGAGCTATGAACTGCAGCATATGCTCCTAGAGCACATTAGTAGCGCACATGATCCGGATCAGCCCTACAACTGTCCGCATTGCACTGAATGCTTCCAGGACGCTGCCTCCCGCACAGTGCACATGAAGAGCGCCCATGTCATCAAGCACTACGAATGCGAGGTGTGCGGCAAAAAGTATGGAGATCGTCATAATCTTCAGCATCACATCGAGAAATATCACTCGGAAACTGATTTCGAGTGCAGCTTGTGTGAGAAGCGTTTCTTTACACGCAAAAGCCTCCATTACCACATGAACTGGCACAAGCCAGAGCGGCAGCTGCGATGTCGCCACAGTGGCTGCGACAGGCTATTCATCAATCAACGACATCTCAAATGCCATGAGGCAACTCACACAACCGGCTCTCGCAAGAGTGAATACTGCGGTTTCTGTGGCAAAGCATTCACACATGTTAAAACCCTACGATGGCATATCTATAGACAGCATGGTGGTGAGAAGCCCTTCAAATGTGCCATTTGCACTGAGGtttttgacTCGTATGCGGAAAAGCGTATTCACATGCTCGAGTTGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAGTGCATGTTCCAATCCTGTCGCCAGGAGTTTGACACCGAACAGGAACTCATCCAGCACATGAGCGTCGAGCATCTCCAACGCGAACCGTCTGCTCCAGTTATTTCGAATAATAAGCGAGTGCTCCAGCGGAAACGGGAGCGCCAATATACGGGTCTCTTTCAATGCGGCAGCTGTTCGCAACGGTTCAACATGAAGTCCGCACTAGAGCGGCACATGGCTGTGCATTCGGCAGATCGACTGCACGCCTGCAGTCACTGCTCCAAGCGCTATAAGCGTGCCCAGGATTTGAAGTGGCATATGAAGACGCATGCTAATGAGAAGCCCAATGTTTGTGATGTTTGCGGCAAGTCATTTGCCCTGAAATATGTACTTACCCAGCATATGCGCAGTCATGAGGttcTCGAGAAGAACTTCAAGTGTGACACCTGTGGACGTTCTTATCTATTTGAGAAGTCTCTGCGCCTCCATCAGCGTGTCCACACGGGCAACACTTACTACAAATGCGATTTGTGTCAGGAGCGCTTTGTGACTCacatcaaatttaaaaCTCATATGAAAAAGGAGCATGATACAAACCAGCCGCATGCCAAAGATTCGCTGGATAATTTGATCAACATTGTGATTTCCTAA
Protein Sequence: METCRTCARCDFENGNNNYWLDLFHPTSWQNEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDAHMLYDKNDEEEHIADDANEIETSTEIEATTTTKATQDTAIIEATSPTPIEIYVETININEIDQSPQPVVDEQTDLTSDYSTLNISYACKFCYKPQASYELQHMLLEHISSAHDPDQPYNCPHCTECFQDAASRTVHMKSAHVIKHYECEVCGKKYGDRHNLQHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFTHVKTLRWHIYRQHGGEKPFKCAICTEVFDSYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMSVEHLQREPSAPVISNNKRVLQRKRERQYTGLFQCGSCSQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHMRSHEVLEKNFKCDTCGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKEHDTNQPHAKDSLDNLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00564814;
80% Identity: iTF_00558919;