Dezo000655.1
Basic Information
- Insect
- Drosophila ezoana
- Gene Symbol
- -
- Assembly
- GCA_035045725.1
- Location
- JAWNOU010000005.1:5908267-5912361[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.011 0.77 10.5 0.3 2 23 35 56 34 56 0.96 2 13 0.0032 0.22 12.2 4.1 1 23 62 85 62 85 0.97 3 13 0.00046 0.032 14.8 1.5 1 23 130 152 130 152 0.91 4 13 8.7 6.2e+02 1.4 2.8 3 22 160 179 158 179 0.89 5 13 0.34 24 5.8 1.7 2 23 453 475 452 475 0.94 6 13 0.017 1.2 9.9 0.9 1 23 500 522 500 522 0.98 7 13 1.1 75 4.2 5.2 1 23 530 554 530 554 0.91 8 13 0.27 19 6.1 2.2 2 23 559 581 558 581 0.94 9 13 0.00036 0.025 15.2 0.2 2 21 594 613 593 614 0.93 10 13 0.27 19 6.1 1.0 1 23 622 644 622 644 0.97 11 13 1.1e-06 7.7e-05 23.1 2.8 1 23 650 673 650 673 0.98 12 13 4.3e-05 0.0031 18.0 1.4 1 23 679 701 679 701 0.98 13 13 0.0004 0.029 15.0 2.9 1 23 707 729 707 729 0.95
Sequence Information
- Coding Sequence
- ATGGTTAGATATGAGCATGTGCGTGATATATATGCTTCCCAATCGATAAGTGTAGGACAAAAAATGCTAGTGGAGATCACCACGGACGGCGTACCGAAGCTTCACTGTCCCGTCTGCAACAAGGCCCTCATTTCGCTCGCCGGCTACGTGAAGCATGTCAAGAAACATGAACCGCCGGGCGGCTTCCAGTGCCGCTACTGCGACATCAACTACTGCCACGAGGAAGAGCTGAAGGAGCATGTGAAGAGCACGCACAGCGCCTACATCTGTCGCCTGTGCGTGGGCGGCAATGTTATATTCAGCAGCGAGGCGGAGCACGATGCGCACATCGAGGAGGCGCATCAGGATCGCAAGTTCAATGTGTGCCTAGACGCCATCGAGAAGCCGTTCAAGTGTGAGATTTGCGGCAAAAGCTTTGCGGATCGTGAGAGCAGCCTTAAACATCATTCCGAGCACGCCAACGCGTTGCCCGTGGAGTGCAAATGCTGCGCCATGCGCTTCTCCTGCCCCTCCACCTTGGCCAAGCATCAACGCAAGCGTCCCGACAGCTGCGGTCGCCAGTTGCCGCGCACAAATCGCCATCGCTTGCCCGCTGCAGCAGAGACCGTACCCGCCGAGCTCGCCCAGCAGCATGTCGTGAAGCGCAAACGCGGCAGGCCCAAGAAATGTGCGCCCGTTGCGCCGCCCTCGGAGGATAGCGAGGATGATGTGCCACTGGCCAGCAGGCTGAAGGTGCAGGCGCCTGTCAAGCTGAAACAGGAGTTCATTAGCAGCCAAGAGCTGAGTGATTCAGACGAGGAATATCCTGACTTTGAGCCCAACAATAGCGACGAGGAGCCCGATGCGGTGCAGTTTAAGCTACCCACTCCGGCGCTGGTCAAAGAGGAAGCCATAGATCCGGACTTCGAGTACCAGGATGCAAGTGCCTTTGTCAAGATGGAGGGCAACGGCCTGGACATATATAGCAATGAGAAAGACAAGCTGCTCGATGTGCTGCTCAGCACGGACGAGAGCCTGAAGCCCTTTGAGAATCTCAAAGTGGAGCATGCAACGGGCATACTGGATGAGATTGCCGCCGTGCCCATGGCCAAGCACAATGGCGCCGAGCACATGGAGGAGGATGTGCTGGCGCTGCGGGAAACCGAGCCAGACAGCGCCGAGGAAGACGACGAAGCGGAGCAGTTGCGTCCGCTAACCAAATCCAGTGTTAAGCGAAAATATCGCAAACGCAATGCCACGGCTTCGCCCATGTCGGAGGAGACGACGGCCTCAACAGGACCACGGCGCGTGGCCAAAATAACCAAAAAGGAGCTGAAGGAACGTCTGAAAATGTTGAGCAAAATGGAAAGAACCTGGCAGTGTCCGCACTGTGTTAAAATTTATCACATACGCAAGCCATACGAGAAGCATCTGCGCGACGATCACAAGCTCAACGAGCAGGCCATCAAGGAGCTGTTCAAGGATGCGGATGCGCATGCCAAGCTGGACGAGGAGGTCTTCAAGTGCAAAATATGCAGCAAAATCTATTTGGTAGAGAAGCGCCTGGAGACCCACATGAAGGTGCACGGCCAGGATGGCAGTCTCACCCACAAGTGCCCCTGCTACTGCAATCTGTTCTTCGCCAGCAAGGAACTGGCCACCCAGCACGCACACCAGCAGCACAAGGAGCTGCTGTACTGTGAGAAGTGCGACAAGTATATGACTGGGCACGATAGCCTCAAGAACCACGAGAAGAACTATCATGCACGCAAGGAGCCCCGTAATCTGCCGCGCAATCTGATCTGCGATAAGTGTGGCAAGAAGTTCACCGGGCGCACCTCGCTCTCGGATCATGTGCGCTCCGAGTGCGGCCGTGTGCCGCTCTATGAGTGCAGCGTCTGCTGCAAGCGGCTTTCCACGGCGGGCATATTGAAGACGCACATGCTGCTCCATCAGTCGGAGACGCCCTACCAGTGCGACAAGTGCGGCAAGACCTTCAAGGTGAAGGCGCAGTACAAGTCGCATCTGAAGACGCGCCACACGGACTACAAGCCTTACAAGTGCCATCTCTGTCCCAAGGAGTATCCGTACCGTGAGAGTCTGTTGACGCACATGACTGTGCACACGGGCATCAAACGTTTCCTTTGCAATAATTGCGGCAAGCGCTTCACTTGCATCTCAAATCTGCAGGCACATCGCAAGGTGCATGCGGACACCTGCGGCCAGCTGCCTCTTAATGCCAAGGCGACGCAATATATGGGCGTGCAGCGGGGCAAGCTGCTGATGGGCGCCAAGCCAGAGGCGGGCATGGAGTACGAGGAGACAAAAACGCTAATTGCCCAGGATGTGATCGATCGGGATATGCCCATGGCGCAGGAGCTCAACTTTCCTTCCGATGGCAGCGCGCCGCTGGCCACGGTGCCACTCAACTATGCCTCCTCGCACCTGGTTCCGCATATTGTGCTGCAGACGATGCAGGCGGAGGCACGAGCACAAGATTAG
- Protein Sequence
- MVRYEHVRDIYASQSISVGQKMLVEITTDGVPKLHCPVCNKALISLAGYVKHVKKHEPPGGFQCRYCDINYCHEEELKEHVKSTHSAYICRLCVGGNVIFSSEAEHDAHIEEAHQDRKFNVCLDAIEKPFKCEICGKSFADRESSLKHHSEHANALPVECKCCAMRFSCPSTLAKHQRKRPDSCGRQLPRTNRHRLPAAAETVPAELAQQHVVKRKRGRPKKCAPVAPPSEDSEDDVPLASRLKVQAPVKLKQEFISSQELSDSDEEYPDFEPNNSDEEPDAVQFKLPTPALVKEEAIDPDFEYQDASAFVKMEGNGLDIYSNEKDKLLDVLLSTDESLKPFENLKVEHATGILDEIAAVPMAKHNGAEHMEEDVLALRETEPDSAEEDDEAEQLRPLTKSSVKRKYRKRNATASPMSEETTASTGPRRVAKITKKELKERLKMLSKMERTWQCPHCVKIYHIRKPYEKHLRDDHKLNEQAIKELFKDADAHAKLDEEVFKCKICSKIYLVEKRLETHMKVHGQDGSLTHKCPCYCNLFFASKELATQHAHQQHKELLYCEKCDKYMTGHDSLKNHEKNYHARKEPRNLPRNLICDKCGKKFTGRTSLSDHVRSECGRVPLYECSVCCKRLSTAGILKTHMLLHQSETPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASSHLVPHIVLQTMQAEARAQD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00563429; iTF_00534829; iTF_00617141; iTF_00475455; iTF_00526816; iTF_00598369; iTF_00491016; iTF_00582473; iTF_00587598; iTF_00595438; iTF_00589736; iTF_00579488; iTF_00472545; iTF_00562657; iTF_00553893; iTF_00523204; iTF_00529063; iTF_00558155; iTF_00608676; iTF_00507122; iTF_00575858; iTF_00585458; iTF_00569203; iTF_00520821; iTF_00509284; iTF_00614381; iTF_00602071; iTF_00534099; iTF_00602069; iTF_00610904; iTF_00510809; iTF_00537767; iTF_00519417; iTF_00583929; iTF_00471103; iTF_00478957; iTF_00586207; iTF_00530448; iTF_01549745; iTF_00479698; iTF_00496115; iTF_00531187; iTF_00473281; iTF_00554593; iTF_00551778; iTF_00540584; iTF_00516511; iTF_00549760; iTF_01557762; iTF_00497635; iTF_00576555; iTF_00528273; iTF_00567033; iTF_00544740; iTF_01551205; iTF_01557025; iTF_01551946; iTF_01558506; iTF_01550476; iTF_01559930; iTF_01555613; iTF_00620071; iTF_00495338; iTF_00549034; iTF_01559243; iTF_01554914; iTF_00545484; iTF_00572817; iTF_00610125; iTF_00805454; iTF_00511503; iTF_00499089; iTF_00543954; iTF_00496848; iTF_00521621; iTF_00597622; iTF_00599091; iTF_00803123; iTF_01549076; iTF_00535543; iTF_00803864; iTF_01552664; iTF_00546875; iTF_00525372; iTF_00567805; iTF_00541979; iTF_01554173; iTF_00573567; iTF_00508576; iTF_00589043; iTF_01553429; iTF_00568502; iTF_00586922; iTF_00561274; iTF_00547570; iTF_01320669; iTF_01322881; iTF_01327362; iTF_01325128; iTF_01322155; iTF_01326647; iTF_01323596; iTF_01321389; iTF_01325858; iTF_01328087; iTF_01324366; iTF_00532638; iTF_00806206; iTF_01556321; iTF_01570462; iTF_00551103; iTF_00510048; iTF_00599824; iTF_00493867; iTF_00559739; iTF_00520167; iTF_00476880; iTF_00512986; iTF_00502779;
- 90% Identity
- iTF_00582473;
- 80% Identity
- -