Basic Information

Insect: Drosophila meridionalis
Gene Symbol: -
Assembly: GCA_035045145.1
Location: JAWNPG010000031.1:14717726-14721524[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0079 0.55 10.9 0.3 2 23 25 46 24 46 0.96

2 12 0.067 4.7 8.0 9.8 1 23 52 75 52 75 0.98

3 12 0.00045 0.032 14.8 1.2 1 23 116 138 116 138 0.95

4 12 0.3 21 5.9 1.7 2 23 406 428 405 428 0.94

5 12 0.016 1.1 9.9 0.9 1 23 453 475 453 475 0.98

6 12 0.95 67 4.3 5.2 1 23 483 507 483 507 0.91

7 12 0.24 17 6.2 2.2 2 23 512 534 511 534 0.94

8 12 0.00032 0.023 15.2 0.2 2 21 547 566 546 567 0.93

9 12 0.24 17 6.2 1.0 1 23 575 597 575 597 0.97

10 12 9.8e-07 6.9e-05 23.2 2.8 1 23 603 626 603 626 0.98

11 12 3.9e-05 0.0027 18.1 1.4 1 23 632 654 632 654 0.98

12 12 0.00036 0.025 15.1 2.9 1 23 660 682 660 682 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0079	0.55	10.9	0.3	2	23	25	46	24	46	0.96
2	12	0.067	4.7	8.0	9.8	1	23	52	75	52	75	0.98
3	12	0.00045	0.032	14.8	1.2	1	23	116	138	116	138	0.95
4	12	0.3	21	5.9	1.7	2	23	406	428	405	428	0.94
5	12	0.016	1.1	9.9	0.9	1	23	453	475	453	475	0.98
6	12	0.95	67	4.3	5.2	1	23	483	507	483	507	0.91
7	12	0.24	17	6.2	2.2	2	23	512	534	511	534	0.94
8	12	0.00032	0.023	15.2	0.2	2	21	547	566	546	567	0.93
9	12	0.24	17	6.2	1.0	1	23	575	597	575	597	0.97
10	12	9.8e-07	6.9e-05	23.2	2.8	1	23	603	626	603	626	0.98
11	12	3.9e-05	0.0027	18.1	1.4	1	23	632	654	632	654	0.98
12	12	0.00036	0.025	15.1	2.9	1	23	660	682	660	682	0.95

Sequence Information

Coding Sequence: ATGGCAGCTCAATCATTGAATGCTGGTCAGAAAATGCTTGTGGAAATAACGACGGACGGCATACCGAAGCTGCACTGCCCCGTCTGCAACAAGGCGTTGGTTTCGCTCGCCGGCTACGTGAAGCATGTGAAGAAGCATGAGCCGCCGGGCGGCTTTCGGTGTCGCTACTGCGAGCACACTTGCTGCCACGAGGAGCAGTTGAAGGAGCACTTGAGGATCACGCACAGCGCCTGCATCGAGTGCCGCCTGTGCCACAGTCTGTTCGGCAGCGAGGTGGAGCACGAGGCACACATCGAGGAAGCGCACCAGGAGCGCAAGTTTAGCGTCAgtcaggagcagcagctcttCAAGTGCGAGCTGTGCGGCAAGTGCTTTGCGGACCGCGAGAGCAGCGCGAAGCACCAGGCCGAGCATGCAGAGAAGTGCAAAGGGAGCTCCCCCGGCCCGGCCAAGCATCAGCGGAACTGTCGACAAGGTTCTCCCATTCCTGCAGATGCACCTGCCCACGTAGTCAAGCGAAAGCGAGGCAGACCAAAGAAATGCCCAGCGCCAGCTTCGGAggacagcgacgacgacgtgCCCCTGGCCAGCAGGCTGAAAGTCCAAGCGCCCATCAAACTGAAACAGGAGTTCGTCAGCAGCCAGGATCTGAGCGACACGGACGAGGAGTACCCCGACTTTGAGCCCAACAACAGCGACGAGGAGGCGGATGCGAATCAGTTCAAGCTACCGCCCCCCGCGCTCGTCAAAGAGGAAGCCATCGATCCCGATTTCGAGTACCAGGATGCCAGCGCCTTTGTCAAAATGGAGGGCAGCAACGGACTGGACATCTACAGCAACGAGAAGGACAAGCTGCTGGATGTGCTGCTCAACCAGGACGAGAGCATGAAGCCCTACGAGCACCTCAAGGTGGAGCACGCAACGGGCATATTGGATGAGATTGCGGCCGTGCCAATGGCCAAGCAGAATGGGGAGGACCACATGGAGGAGGATGTGCTGGCCCTGCGCGAGACGGAGCCGGACAGCGAGGAGGACGCGCCACTGCGTCCGCTCACCAAATCCGGCGTAAAGCGGAAATATCGGAAGAGAGAAACGGCTCCCAATTCGCCTGTGGCCCAGGAAGAGGCGACACCCGCCAAGCGCCGTGTGGCCAAAATAACCAAAAAGGAGTTGAAGGAGCGTCTGAAAATGCTTAGTAAGATGGAGAAGACGTGGCAGTGCCCGCACTGCGTCAAGATCTACCACATCCGCAAGCCGTACGAGAAGCACCTGCGCGACGACCACAAGCTCAGCGAACAGGCGGTCAAGGAGCTGTTCAAGGACGCGGATGCGCATGCCAAGCTGGACGAGGAGGTGTTCAAATGCAAAATCTGCAGCAAGATCTACTTGGTGGAGAAGCGCCTGGAGACGCACATGAAGGTGCACGGCAAGGACGGCAGCCTGATCCACAAGTGCCCCTGCTACTGCAACCTGTTCTTCGCCAGCAAGGAGCTGGCCACCCAGCACGCCCACCAGCAGCACAAGGAGCTGCTCTACTGCGAGAAGTGCGACAAGTACATGACCGGGCATGACAGCTTGAAGAACCACGAGAAGAACTACCACGCCCGCAAGGAGCCGCGCAATCTGCCGCGGAACCTGATCTGCGACAAGTGCGGCAAGAAGTTCACGGGCCGCACCTCCCTCTCGGATCACGTGCGCTCCGAGTGCGGACGCGTGCCCCTTTACGAGTGCAGCGTCTGCTGCAAGCGCCTCTCCACTGCCGGAATACTGAAAACGCACATGCTCCTGCACCAGTCCGAGACGCCATACCAGTGCGACAAGTGTGGCAAGACGTTCAAGGTGAAGGCGCAGTACAAATCCCATTTGAAGACCCGTCACACGGACAACAAGCCCTACAAGTGTCATCTCTGTCCCAAGGAGTATCCATACCGGGAAAGCCTTTTAACCCACATGACCGTTCACACGGGCATCAAGCGCTTCCTGTGCAACAACTGTGGCAAGCGCTTCACATGCATCTCTAATCTGCAGGCGCACCGGAAGGTGCACGCCGACACCTGCGGTCAGCTGCCCCTCAATGCGAAGGCCACGCAATATATGGGCGTGCAGCGAGGCAAATTGCTGATGGGCGCCAAACCAGAGGCGGGCATGGAATACGAGGAGACGAAGACTCTAATCGCCCAGGACGTGATCGATCGGGATATGCCGATGGCGCAGGAGCTGAACTTTCCATCCGATGGCAGCGCGCCGCTGGCCACGGTTCCACTCAACTACGCTTCGTCACATTTGGTGCCGCACATTGTGCTGCAGACGATGCAGGCCGAGGCGAGGACACAGGATTAG
Protein Sequence: MAAQSLNAGQKMLVEITTDGIPKLHCPVCNKALVSLAGYVKHVKKHEPPGGFRCRYCEHTCCHEEQLKEHLRITHSACIECRLCHSLFGSEVEHEAHIEEAHQERKFSVSQEQQLFKCELCGKCFADRESSAKHQAEHAEKCKGSSPGPAKHQRNCRQGSPIPADAPAHVVKRKRGRPKKCPAPASEDSDDDVPLASRLKVQAPIKLKQEFVSSQDLSDTDEEYPDFEPNNSDEEADANQFKLPPPALVKEEAIDPDFEYQDASAFVKMEGSNGLDIYSNEKDKLLDVLLNQDESMKPYEHLKVEHATGILDEIAAVPMAKQNGEDHMEEDVLALRETEPDSEEDAPLRPLTKSGVKRKYRKRETAPNSPVAQEEATPAKRRVAKITKKELKERLKMLSKMEKTWQCPHCVKIYHIRKPYEKHLRDDHKLSEQAVKELFKDADAHAKLDEEVFKCKICSKIYLVEKRLETHMKVHGKDGSLIHKCPCYCNLFFASKELATQHAHQQHKELLYCEKCDKYMTGHDSLKNHEKNYHARKEPRNLPRNLICDKCGKKFTGRTSLSDHVRSECGRVPLYECSVCCKRLSTAGILKTHMLLHQSETPYQCDKCGKTFKVKAQYKSHLKTRHTDNKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASSHLVPHIVLQTMQAEARTQD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506346;
90% Identity: iTF_00532638;
80% Identity: -