Basic Information

Insect: Drosophila nigricruria
Gene Symbol: -
Assembly: GCA_037075265.1
Location: JBAMCI010000173.1:1789421-1793944[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.01 0.71 10.6 0.3 2 23 35 56 34 56 0.96

2 12 1.3 93 3.9 9.6 1 23 62 85 62 85 0.97

3 12 3.4e-05 0.0025 18.3 1.1 1 23 131 153 131 153 0.97

4 12 0.31 22 5.9 1.7 2 23 417 439 416 439 0.94

5 12 0.016 1.1 9.9 0.9 1 23 464 486 464 486 0.98

6 12 0.97 70 4.3 5.2 1 23 494 518 494 518 0.91

7 12 0.25 18 6.2 2.2 2 23 523 545 522 545 0.94

8 12 0.00033 0.024 15.2 0.2 2 21 558 577 557 578 0.93

9 12 0.25 18 6.2 1.0 1 23 586 608 586 608 0.97

10 12 1e-06 7.2e-05 23.1 2.8 1 23 614 637 614 637 0.98

11 12 4e-05 0.0028 18.1 1.4 1 23 643 665 643 665 0.98

12 12 0.00037 0.026 15.1 2.9 1 23 671 693 671 693 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.01	0.71	10.6	0.3	2	23	35	56	34	56	0.96
2	12	1.3	93	3.9	9.6	1	23	62	85	62	85	0.97
3	12	3.4e-05	0.0025	18.3	1.1	1	23	131	153	131	153	0.97
4	12	0.31	22	5.9	1.7	2	23	417	439	416	439	0.94
5	12	0.016	1.1	9.9	0.9	1	23	464	486	464	486	0.98
6	12	0.97	70	4.3	5.2	1	23	494	518	494	518	0.91
7	12	0.25	18	6.2	2.2	2	23	523	545	522	545	0.94
8	12	0.00033	0.024	15.2	0.2	2	21	558	577	557	578	0.93
9	12	0.25	18	6.2	1.0	1	23	586	608	586	608	0.97
10	12	1e-06	7.2e-05	23.1	2.8	1	23	614	637	614	637	0.98
11	12	4e-05	0.0028	18.1	1.4	1	23	643	665	643	665	0.98
12	12	0.00037	0.026	15.1	2.9	1	23	671	693	671	693	0.95

Sequence Information

Coding Sequence: ATGGTTAGCAATGAGCGTGTGCGTGATATACATGCAGCTCAATCGTTGAATGCTGGTCAGAAGATGCTTGTGGAGATAACGACGGATGGCATTCCGAAGCTCCACTGTCCGGTCTGCAACAAGGCATTAATTTCGCTCGCCGGCTACGTGAAGCATGTGAAGAAGCATGAGCCGCCGGGCGGCTTTCGGTGTCGCTTCTGCGCGCACACCTGCTGCCATGAGGAGCAGCTGAAGGAGCACTTGAGGATCACACACAGCAGTGCCTATATCGAGTGTCGCCTGTGCCACAGTCTGTTCGGCAGCGAGGCGGAGCACGAGGCGCACATCGAGGAAGCGCATCAGGAGCGCAAGTTCAATGTAAGCCAGGATCAGGATCAGGATCAGCAGCTGTTCAAGTGCGAGCTGTGCGGCAAGTGCTTTGCGGACCGCGAGAGCAACGCGAAGCATCAGGCCGAGCACAAAGGGAGCTCCGCCAGCCCGGCCAAGCAGCAACGAAACTGTCGACAAGGTTCTTCCATTCCTGCGGACGGACCTGCTCATGTAGTCAAGCGAAAGCGGGGCAGGCCCAAGAAGTGTCCGGCGCCGGCTTCAGAGGACAGCGACGACGATGTGCCCCTCGCCAGCAGGCTGAAAGTTCAAGCACCTATCAAGCTAAAGCAGGAGTTCGTTAGCAGCCAGGAACTAAGCGATACGGACGAGGAGTATCCCGACTTTGAGCCCAACAACAGCGACGAGGAAGCGGATGCGACTCAGTTTAAGCTACCTCCCCCAGCTCTCGTCAAAGAGGAGGCCATCGATCCCGACTTTGAGTATCAGGATGCAAGCGCCTTTGTTAAAATGGAGGGCAATAATGGCCTGGACATCTACAGCAATGAAAAGGACAAGCTGCTGGATGTGCTGCTCAACCAGGATGAGAGCATGAAGCCCTACGAGCATTTAAAAGTGGAGCATGCAACGGGCATATTGGATGAGATTGCCGCCGTGCCCATGGCCAAGCAGAATGGGGAGGACCACATGGAGGAGGATGTGCTGGCATTGCGCGAAACAGAGCCGGAcagcgaggaggaggagcaacTGCGTCCACTAACCAAATCCAGTGTCAAGCGCAAGTATCGAAAGCGAGGAGCAGCTACCGCCTCGCCTGTGGCTCAGGAAGAGGTAACAACAGCTCCACGCCGCGTGGCCAAAATAACCAAAAAAGAGCTGAAGGAGCGCCTGAAAATGCTGAGTAAAATGGAAAAGACCTGGCAATGTCCACACTGTGTGAAGATCTATCACATTCGCAAGCCATATGAGAAGCATCTGCGCGACGATCACAAGCTAAGCGAACAGGCGGTCAAGGAGCTCTTCAAGGATGCAGACGCACATGCCAAACTGGACGAAGAAGTCTTCAAATGTAAAATCTGCAGCAAAATCTACTTGGTAGAGAAACGCCTGGAGACGCACATGAAGGTGCACGGCAAGGATGGCAGTCTAATACACAAGTGTCCCTGCTATTGCAATCTGTTCTTCGCCAGCAAAGAGCTAGCCACCCAGCACGCCCACCAGCAGCACAAGGAGCTGCTCTACTGTGAGAAGTGTGACAAGTATATGACTGGGCATGACAGCTTGAAGAATCACGAGAAGAACTATCACGCCCGCAAGGAGCCGCGCAATCTGCCCCGGAATCTGATTTGCGATAAGTGCGGCAAGAAGTTCACGGGGCGTACCTCTCTCTCCGATCACGTGCGCTCCGAGTGTGGACGAGTGCCTCTGTACGAGTGCAGTGTCTGCTGCAAGCGACTCTCCACAGCCGGCATACTAAAGACGCACATGCTCCTGCATCAGTCGGAGACGCCGTATCAGTGCGACAAGTGCGGAAAGACGTTCAAGGTGAAGGCGCAGTACAAATCGCATCTGAAGACCCGTCACACGGACAACAAGCCCTACAAGTGCCATCTCTGTCCCAAGGAGTATCCATATCGGGAAAGCCTTCTAACCCATATGACTGTTCACACGGGCATCAAACGCTTCCTTTGCAACAACTGCGGCAAACGCTTCACATGCATCTCCAATCTGCAGGCGCATCGCAAGGTGCACGCCGACACCTGCGGCCAGTTGCCCCTCAATGCGAAGGCCACGCAATATATGGGCGTGCAGCGAGGCAAACTGCTGATGGGCGCCAAGCCAGAGGCGGGCATGGAATACGAGGAGACAAAAACCCTGATTGCCCAGGATGTGATCGATCGGGATATGCCGATGGCGCAGGAACTCAACTTTCCATCCGACGGCAGCGCGCCGCTGGCAACGGTTCCACTCAATTATGCTTCCTCGCATCTGGTGCCGCACATTGTGCTGCAGACGATGCAGGCTGAGGCGAGGACACAGGATTAG
Protein Sequence: MVSNERVRDIHAAQSLNAGQKMLVEITTDGIPKLHCPVCNKALISLAGYVKHVKKHEPPGGFRCRFCAHTCCHEEQLKEHLRITHSSAYIECRLCHSLFGSEAEHEAHIEEAHQERKFNVSQDQDQDQQLFKCELCGKCFADRESNAKHQAEHKGSSASPAKQQRNCRQGSSIPADGPAHVVKRKRGRPKKCPAPASEDSDDDVPLASRLKVQAPIKLKQEFVSSQELSDTDEEYPDFEPNNSDEEADATQFKLPPPALVKEEAIDPDFEYQDASAFVKMEGNNGLDIYSNEKDKLLDVLLNQDESMKPYEHLKVEHATGILDEIAAVPMAKQNGEDHMEEDVLALRETEPDSEEEEQLRPLTKSSVKRKYRKRGAATASPVAQEEVTTAPRRVAKITKKELKERLKMLSKMEKTWQCPHCVKIYHIRKPYEKHLRDDHKLSEQAVKELFKDADAHAKLDEEVFKCKICSKIYLVEKRLETHMKVHGKDGSLIHKCPCYCNLFFASKELATQHAHQQHKELLYCEKCDKYMTGHDSLKNHEKNYHARKEPRNLPRNLICDKCGKKFTGRTSLSDHVRSECGRVPLYECSVCCKRLSTAGILKTHMLLHQSETPYQCDKCGKTFKVKAQYKSHLKTRHTDNKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASSHLVPHIVLQTMQAEARTQD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506346;
90% Identity: iTF_00532638;
80% Identity: -