Dkan013391.1
Basic Information
- Insect
- Drosophila kanekoi
- Gene Symbol
- -
- Assembly
- GCA_037075305.1
- Location
- JBAMCE010000577.1:8187902-8190904[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.011 0.7 10.5 0.3 2 23 14 35 13 35 0.96 2 13 0.011 0.75 10.4 6.2 1 23 41 64 41 64 0.97 3 13 0.00051 0.034 14.7 1.5 1 23 109 131 109 131 0.91 4 13 8.5 5.6e+02 1.4 2.8 3 22 139 158 137 158 0.89 5 13 0.33 22 5.8 1.7 2 23 432 454 431 454 0.94 6 13 0.017 1.1 9.9 0.9 1 23 479 501 479 501 0.98 7 13 1 68 4.3 5.2 1 23 509 533 509 533 0.91 8 13 0.26 17 6.2 2.2 2 23 538 560 537 560 0.94 9 13 0.00035 0.023 15.2 0.2 2 21 573 592 572 593 0.93 10 13 0.26 17 6.2 1.0 1 23 601 623 601 623 0.97 11 13 1.1e-06 7e-05 23.1 2.8 1 23 629 652 629 652 0.98 12 13 4.2e-05 0.0028 18.1 1.4 1 23 658 680 658 680 0.98 13 13 0.00039 0.026 15.0 2.9 1 23 686 708 686 708 0.95
Sequence Information
- Coding Sequence
- ATGCTAGTGGAGATTACCACGGACGGTGTACCGAAGCTTCACTGTCCCGTGTGCAACAAGGCCCTCATTTCACTCGCCGGCTACGTTAAGCATGTCAAGAAACACGAACCGCCGGGCGGCTTCCAGTGCCGCTACTGCGACATCCACTATTGCCACGAGGAGGAGCTGAAGGAGCACGTGAAGAGCACGCACAGCGCCTACATCTGTCGCCTGTGCGTGGGCGGCAATGTTATATTCAGCAGCGAGGCGGAACACGATGCGCACATCGAGGAGGCGCACCAGGATCGCAAGTTCAACGTGTGCCTAGATGCCATCGAAAAGCCGTTCAAGTGTGAGATTTGCGGCAAAAGCTTTCCGGATCGTGAGAGCAGCCTGAAACATCATTCCGAGCACGCCAACGCGTTGCCCGTGGAGTGCAAATGCTGCGCCATGCGCTTCTCCTGCCCCTCCACCTTGGCCAAGCATCAACGCAAGCGTCCCGACAGCTGCGGTCGTCAGTTGCCGCGCACAAATCGCCATCGCTTGCCCGCTGCAGCAGAGCCAGTACCCGCCGAGCTTGCCCAGCGGCATGTCGTCAAGCGTAAACGCGGCAGGCCCAAGAAATGTGATCCCGTTGTGCCGGCCTCGGAGGATAGCGAGGATGATGTGCCGCTGGCCAGCAGGCTGAAGGTGCAGGCGCCTGTCAAGCTGAAACAGGAGTTCATTAGCAGCCAGGAGCTGAGTGATTCAGACGAGGAATATCCTGACTTTGAGCCCAACAATAGCGATGAGGAGCCAGACGCGGTGCAGTTTAAGTTACCAACTCCGGCGCTGGTCAAAGAGGAAGCCGTAGATCCGGACTTTGAGTACCAGGATGCGAGTGCCTTTGTCAAGATGGAGGGTAACGGCCTGGACATATATAGCAATGAGAAAGACAAACTGCTCGATGTGCTGCTTAGCACGGACGAGAGCTTGAAGCCCTTTGAGAATCTCAAAGTGGAGCATGCAACCGGCATACTGGATGAGATTGCCGCCGTGCCCATGGCCAAGCACAATGGTGCCGAGCATATGGAGGAGGATGTGCTGGCGCTGCGCGAAACCGAGCCAGACAGCGCCGAGGAGGACGACGAAGTGGAGCAGCTGCGTCCGCTGACCAAATCCAGTGTTAAGAGAAAATATCGCAAACGCACTGCCATGGCTTCGCCAATGCCGGAGGAGACGACGGCCTCAACAGGACCACGACGGGTGGccaaaataaccaaaaaggAGCTGAAGGAGCGTCTGAAAATGTTGAGCAAAATGGAAAGAACATGGCAGTGTCCGCACTGTGTTAAAATCTATCACATACGCAAGCCTTACGAGAAGCATCTGCGTGACGATCACAAGCTCAACGAGCAGGCCATCAAGGAGCTGTTCAAGGATGCGGATGCGCATGCCAAGCTGGACGAGGAGGTCTTCAAGTGCAAAATATGTAGCAAAATCTATTTGGTGGAGAAGCGCCTGGAGACCCATATGAAGGTTCATGGCGAGGATGGCAGCCTCACCCACAAGTGCCCCTGTTACTGCAATCTGTTCTTTGCCAGCAAGGAACTGGCCACTCAGCACGCACACCAGCAGCACAAGGAGCTGCTCTACTGTGAGAAGTGCGACAAGTATATGACTGGGCATGATAGCCTCAAGAACCACGAGAAGAACTATCATGCTCGCAAGGAGCCCCGTAATATGCCGCGCAATCTGATCTGCGATAAGTGTGGCAAGAAGTTCACCGGGCGCACCTCGCTCTCGGATCATGTGCGCTCCGAGTGCGGCCGTGTGCCGCTCTATGAGTGCAGCGTCTGCTGCAAGCGCCTTTCCACGGCGGGCATATTGAAGACGCACATGCTGCTCCATCAGTCGGAGACGCCCTATCAGTGCGACAAGTGCGGCAAGACCTTCAAGGTGAAGGCGCAGTACAAGTCGCATCTGAAGACGCGCCACACGGACTACAAGCCTTACAAGTGCCATCTCTGTCCCAAGGAATATCCGTACCGTGAGAGTCTGTTGACGCACATGACTGTGCACACGGGCATCAAACGTTTCCTTTGCAATAATTGCGGCAAGCGCTTCACTTGCATTTCAAATCTGCAGGCACATCGCAAGGTGCATGCAGACACTTGCGGGCAGTTGCCTTTAAATGCCAAGGCGACGCAATATATGGGCGTGCAGCGGGGCAAGCTGCTGATGGGCGCCAAGCCGGAGGCGGGCATGGAGTACGAGGAGACAAAAACACTGATTGCCCAGGATGTGATCGATCGAGATATGCCCATGGCGCAGGAGCTCAACTTTCCTTCCGACGGCAGTGCGCCGTTGGCCACAGTGCCACTCAACTATGCCTCCTCGCACCTGGTTCCGCATATTGTGCTGCAGACGATGCAGGCGGAGGCACGAGCACAGGATTAG
- Protein Sequence
- MLVEITTDGVPKLHCPVCNKALISLAGYVKHVKKHEPPGGFQCRYCDIHYCHEEELKEHVKSTHSAYICRLCVGGNVIFSSEAEHDAHIEEAHQDRKFNVCLDAIEKPFKCEICGKSFPDRESSLKHHSEHANALPVECKCCAMRFSCPSTLAKHQRKRPDSCGRQLPRTNRHRLPAAAEPVPAELAQRHVVKRKRGRPKKCDPVVPASEDSEDDVPLASRLKVQAPVKLKQEFISSQELSDSDEEYPDFEPNNSDEEPDAVQFKLPTPALVKEEAVDPDFEYQDASAFVKMEGNGLDIYSNEKDKLLDVLLSTDESLKPFENLKVEHATGILDEIAAVPMAKHNGAEHMEEDVLALRETEPDSAEEDDEVEQLRPLTKSSVKRKYRKRTAMASPMPEETTASTGPRRVAKITKKELKERLKMLSKMERTWQCPHCVKIYHIRKPYEKHLRDDHKLNEQAIKELFKDADAHAKLDEEVFKCKICSKIYLVEKRLETHMKVHGEDGSLTHKCPCYCNLFFASKELATQHAHQQHKELLYCEKCDKYMTGHDSLKNHEKNYHARKEPRNMPRNLICDKCGKKFTGRTSLSDHVRSECGRVPLYECSVCCKRLSTAGILKTHMLLHQSETPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASSHLVPHIVLQTMQAEARAQD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00506346;
- 90% Identity
- iTF_00582473;
- 80% Identity
- -