Dboc007308.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila bocki
Gene Symbol
-
Assembly
GCA_008042715.1
Location
VNJY01000469.1:2260-5228[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.9 3.5e+02 1.8 0.9 2 23 148 170 147 170 0.92
2 13 0.0019 0.13 12.6 5.0 1 23 188 211 188 211 0.97
3 13 3.5e-06 0.00025 21.2 5.5 2 23 218 240 217 240 0.96
4 13 0.0097 0.7 10.3 9.1 2 23 495 516 495 516 0.97
5 13 1.7e-06 0.00012 22.2 2.9 1 23 522 545 522 545 0.95
6 13 9.9e-05 0.0071 16.6 0.3 1 23 550 573 550 573 0.93
7 13 5.5e-05 0.004 17.4 5.5 1 23 591 613 591 613 0.96
8 13 0.00021 0.015 15.6 0.7 1 23 618 640 618 640 0.98
9 13 2.9e-05 0.0021 18.3 1.7 1 23 646 668 646 668 0.95
10 13 2.1e-05 0.0015 18.7 0.7 1 23 674 696 674 696 0.98
11 13 3e-07 2.2e-05 24.5 2.7 3 23 704 724 703 724 0.99
12 13 2.2e-08 1.6e-06 28.1 1.1 1 23 730 752 730 752 0.99
13 13 0.33 24 5.5 3.4 1 19 757 775 757 780 0.89

Sequence Information

Coding Sequence
ATGCACCCAGCAAGAGCTATAGCCATGGCATCCCACTACCCGCTCCCGCAGCCCGATCCGGGTCTCAAGTCCGAGACGCAGCTGGCGGGCGATAGGTTGGTCACCCTGGATGCCGTTGACGCGGACCGCGTCTGCCGCGTTTGCCTTAAGGACGCCTCCCAGGACGGCGAGCTGCACTTCATCTTTGCGGACGGACCGCTGGAACTGGGCGCCAACTTGGCGCGCATCCTGGACGAGTGTACGCTGCATCCGTGCGAGCGGCAAGATGGTATGCCGTCCAACATGTGCGGCTCCTGCGTGGAGGCGGCTCGCCACGCCTACCGCTTCAAGCGCAACGCCGAGCGCTCCTACTGCTCTCTGGTGGCGCTGCTCGGCCGCTCCCCGCAGTTAAAGTCCAATGGCGCCGAGGCTGGCACCCAGACCGACCAGGTGGCCCTGCTGCCCTGCGAGATGTGTCACGACCAGTTCCTCAATAGCTTGGAGCTGCGCCTGCACCGCAACCGGGTGCACAGAATAGCGAAGGATGGCACTGAAGGCAACGACGGTGGTGCTGTCGAGGAATTCAAGTGCAAGTTCTGTCCGCAGCACTTCCCGCATCTCCGACAGCTGCGCAGTCACTTGGCACGCAGCCACGAGCAGACCGCTCGCCTTCAGTGCGCCCACTGCCAGCGCACCTTCAGTCGCCGGGATCATCTGCTGCGACACATGCGTAACCAACACCGTCACCTGGAAGACGACCTCTTAAACACTTGGCCGCCGGCGGATGAGACCACCATGCAAAGCTCTGCGGGTGATGAGCTTGTCTCGGCGGAAGTGCTCCTCAGCGAGGAAAAGGATAACCCTGAGGATGGCGATATCTTCCAATGCAACACGAATCCCATTTCCAGCaacgaggaggacgacgacgacgatgaggatAACGTAGAGGCTAAGCAGTCACTGTGGCTGCACATCAAGCCAGAGCCCTGCCTGGAGGCTGAGGAAGTTAGCCTGGCCACGCAACTgaagctggagaagaagcagcagcggcggcggcggcggcggcgtgggGAAAAGGCGGAGCCGCGTTTAGGGAGCTCCAGTGACTCGCCGGTGAAGCGTGAGCCCCTGGCCGCTGGCGACCCTCAACTCAGCATCAAGCAGGAGAGCCAGCTGGTGGGCAGCGAGGATGAGGCGCCCATGGGTGTGGAGGAGTTCATGGCGCTGCATGCCACGGGAGAGCTGCCGTTTAGCGATGAGGAACATTTCGGTGActacggagacggagacgacGAAAGTGCTTTGgatgacgacgaggaggaggaggaggaggaggacgaggacgacgacgatgaagaTGCAGATGAAGATGCAGATGGAAACGATGGGGATTTTAAGCTGAAAGTGGAGCCGCTGGACGGTGAGCAGCAGTCGCCCAAGAAGTCCAAGTCtggcaggcggcggcggcgtcgcCGCAGCAATGGCGAGCCCAATCCCGAAAACCGTTGCGATGTCTGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCCCACCTGGAGAAGAAGCCCCACAATTGCCCGCACTGTCCCAAGGCATTTGCGCGCAGCGATCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAACAAGGAGCACAAGTGCGGCATCTGCGAGGCGGCCTTCTCCCGTCCGGATGCCCTCGAGCGGCACAAGGTGAGCAAGCACAACGGCGAGGGCCTGGAGCCGGGCAGTGAGCTCAAGCTGCAGCTGGCGGAGCACACCTGCGAGTACTGCTCCAAGCGCTTCTCCAGCAAAACGTACTTGCGGAAGCACACCCTGCTGCATACGGACTTCCTCTATGCCTGCAAGAGCTGCGAGGAGACATTCCGCGAGCGCGGCCAGCTGCGAGAGCACGAGAAGACGCACACCGGGCAGCGCAACTTCCTTTGCTGCATTTGCGGCGATAGCTTTGCCCGGAATGACTACCTCCGTGTCCATATGCGGCGTCATAATGGTGAGAAGCCCTACAAGTGCCGCTACTGTGTGAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTCCACGAGCGCTATCACACCAACACGAAACCGAACCTGTGCAATACCTGCGGCAAGAGCTTTCACCGGGCCTATAACCTGACCATCCACATGCGCACCCACACCGGCGAGCGACCCTACAAGTGCGACCAGTGCCCCAAGAGCTTTACGCAGAGCAACGACCTCAAGGCTCACATTCGCCGGCACACGGGTGAGCGGTACAAGTGTCCCCACTGCGATGCCTACTTCCTGCAGCTGTACAACATGCGCAACCACTGTTTGAGTGCCCACAACAAGCACATTGAGACGAAGACGGGACGCCTGCAGAGGACAGGTCTGCTGGATGATGGTGGCCAGTCGCATCTCACCACCGTGGTGATGCCGCCATCACAGCTGGCAAcaacggctgctgctgctgctgctgctgctgctgctgtcaccGATAACACCTCCTCTTCCACGGTTATACACTCGCCAGAAGGGTATAGCAGCAATGCGGGAGtggctggagcaggagcaggagcaggttCCACCACTCTGGATGGTGCCAGCTTTGCGCCGACGCCAGTCAATGCCTCCTTTGGGGCTTTTAACTTTCCACCCGCTGTAATGGCTCATCTCATGTACAACCACGGCGGCGCCACTAGCCAGCACAGTCAGAGTGGCAGCGACACGGGCAAATAG
Protein Sequence
MHPARAIAMASHYPLPQPDPGLKSETQLAGDRLVTLDAVDADRVCRVCLKDASQDGELHFIFADGPLELGANLARILDECTLHPCERQDGMPSNMCGSCVEAARHAYRFKRNAERSYCSLVALLGRSPQLKSNGAEAGTQTDQVALLPCEMCHDQFLNSLELRLHRNRVHRIAKDGTEGNDGGAVEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCQRTFSRRDHLLRHMRNQHRHLEDDLLNTWPPADETTMQSSAGDELVSAEVLLSEEKDNPEDGDIFQCNTNPISSNEEDDDDDEDNVEAKQSLWLHIKPEPCLEAEEVSLATQLKLEKKQQRRRRRRRGEKAEPRLGSSSDSPVKREPLAAGDPQLSIKQESQLVGSEDEAPMGVEEFMALHATGELPFSDEEHFGDYGDGDDESALDDDEEEEEEEDEDDDDEDADEDADGNDGDFKLKVEPLDGEQQSPKKSKSGRRRRRRRSNGEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGICEAAFSRPDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERGQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLATTAAAAAAAAAAVTDNTSSSTVIHSPEGYSSNAGVAGAGAGAGSTTLDGASFAPTPVNASFGAFNFPPAVMAHLMYNHGGATSQHSQSGSDTGK