Dtru000972.1
Basic Information
- Insect
- Drosophila truncata
- Gene Symbol
- -
- Assembly
- GCA_008042515.1
- Location
- VNJQ01001256.1:6155-9064[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.4 3.9e+02 1.9 0.8 2 23 148 170 147 170 0.92 2 13 0.0018 0.15 12.6 5.0 1 23 191 214 191 214 0.97 3 13 2.3e-06 0.0002 21.7 5.6 2 23 221 243 220 243 0.96 4 13 0.0092 0.8 10.3 9.1 2 23 487 508 487 508 0.97 5 13 1.6e-06 0.00014 22.2 2.9 1 23 514 537 514 537 0.95 6 13 0.00017 0.015 15.8 0.6 1 23 542 565 542 565 0.93 7 13 5.2e-05 0.0046 17.4 5.5 1 23 583 605 583 605 0.96 8 13 0.00021 0.018 15.5 0.6 1 23 610 632 610 632 0.98 9 13 2.7e-05 0.0024 18.3 1.7 1 23 638 660 638 660 0.95 10 13 2e-05 0.0017 18.8 0.7 1 23 666 688 666 688 0.98 11 13 2.9e-07 2.5e-05 24.5 2.7 3 23 696 716 695 716 0.99 12 13 2.1e-08 1.8e-06 28.1 1.1 1 23 722 744 722 744 0.99 13 13 0.32 28 5.5 3.4 1 19 749 767 749 772 0.89
Sequence Information
- Coding Sequence
- ATGCACCCATCCAGAGCTATAGCCATGGCATCGCACTACCCGCACCCGCAGCCCGATCCGGATCTCAAGTCCGAGACAGAGCCGGCGGGCGGTATGTTGGTCGCTTTGGATTCCATTGACGCGGACCGCGTCTGCCGCGTTTGCCTTAAGGACGCTTCACAGGACGGCGAGCAGCACTTCATCTTCGCGGAGGGGCCACTAGAGCTGGGCGCCAACTTGGCGCGCATCCTGAACGAGTGTACGCTGCATCCGTGCGAGCGACACGACGGTATGCCGTCGAACATGTGCGGCTCCTGCGTGGAGGCAGCCCGCCACGCCTACCGCTTTAAGCGCAATGCCGAGCGATCCTACTGCTCCTTGGTGGCACTGCTCGACCGCTCCCCGCAGTTAAAGTCCAGTGGCGCCGAAGCAGGCACCCAGACCGATCAGGTGGCCCTCTTGCCCTGCGAAATGTGCCACGACCAGTTCCTTAACAGCCTGGAGCTGCGCCTGCACCGCAACCGGGCGcacaggacgacgacgacgacgaaggaGGGCACTGAAGGCAACGACGGAGCCGTAGGCGAGGAATTCAAGTGCAAGTTCTGTCCGCAGCATTTCCCGCATCTTCGACAGCTACGCAGCCACTTGGCGCGCAGCCACGAGCAGACCGCTCGCCTTCAGTGCGGCCACTGCCAGCGCACCTTCAGTCGCCGGGATCACTTGCTGAGGCACATGCGCAACCAGCACCCACGCCTGGAAGACGACGACCTCTTCCACACTTGGCCGCCGGCGGCGGACGAGACGACCATGCAAAGCTCTGCGGGCGATGAGCTCGTCTCGGCCGAAGTACTCCTCAACGAGAAGGACGAAGACCACGACGAGGGCGATATCTTTCAATGCAACACGAATCCCATTTCCAGCAATGAGGATGAGGACAATGCGGACGATGAGGATAATGTAGAGGCTAAGCAAACGCTGTGGCTGCACATCAAGCCGGAGCCCTGTCTGGAGGCTGAGGAAGTAAGCCTCGCCACGCAGCTAAAGCTTGAGAAGAAGCGGCGGCGACGGGAGAAGACGGAGCCGCGTGTTGCAAGCTCCAGTGATTCGCCGGTGAAACATGAACCCATAGCCGCTGTCGACGCCCAACTAAGCATCAAGCAGGAAAGCCAGCTGGTGGGAAGCGAGGACGAGGCGCCAATGGGTGTGGAGGAGTTCATATCGTTGCACGCATCGAGAGAACTGCCGTTCAGCGATGAGGATCATTTCGGGGACTATGGCGATGAGGAAAGTGCTTtggatgacgatgacgatgacgaggaggaggaagaggatgacgacgatgaagaTGGAGACGGGGACGATGGAGATTTCAAGCTGAAAGTGGAGCCGCTGGACGGTGACCAGTCGCCAAAGAAGAAATCCAAAACCAAAGGCAGGCGACGGCGTCGAAACAAGGGCGAACCCAATCCGGAGAACCGATGCGATGTCTGCCAGCGTACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCCCACCTGGAGAAGAAGCCCCACAACTGCCCGCACTGTCCCAAGGCGTTTGCGCGCAGCGATCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAATAAGGAGCACAAGTGCAGCATCTGCGAGGCGGCCTTCTCTCGCCTGGATGCTCTCGAGCGGCACAAGGTTAGCAAGCACAACGGCGAGGGCCTTGAGCCGGGCAGCGAGCTCAAACTGCAGCTAGCGGAGCACACTTGCGAGTATTGCTCCAAGCGTTTCTCCAGCAAAACGTACTTGCGTAAGCACACGCTGCTTCACACCGATTTCCTTTATGCCTGCAAGAGCTGCGAAGAGACATTCCGGGAGCGTGCCCAGCTGCGAGAGCATGAGAAGACGCATACCGGGCAACGCAACTTCCTGTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTACCTCCGCGTCCATATGCGGCGCCACAATGGCGAGAAGCCCTACAAGTGCCGCTACTGTGTCAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTCCACGAGCGGTACCACACAAACACGAAACCGAACCTGTGCAATACCTGCGGCAAGAGCTTTCACCGGGCCTATAATCTGACCATTCACATGCGCACCCACACCGGCGAGCGACCCTACAAATGTGACCAGTGCCCCAAGAGCTTCACGCAGAGCAATGACCTCAAGGCGCACATTCGCCGGCACACGGGCGAGCGTTACAAGTGTCCCCACTGTGATGCCTACTTTCTGCAGCTGTACAACATGCGCAATCACTGCCTGAGCGCTCACAACAAGCACATTGAAACGAAGACGGGACGCTTGCAGCGAACGGGTCTGCTGGACGATGGCGGTCAGTCACATCTCACCACGGTTGTGATGCCGCCATCAcagctggcagcagcagcggcagcgggtgTTGGTACCGAGAGCACCTCCTCTTCCACGGTTATCCACTCGCCGGAAgcctacagcagcagcaatgccacagcagcagcagcagcagtagcagtagcaggaacagcagcaggagcagcttccACTACCCTTGATGGCGCCAGCTTTGCCCCAACGCCGGTCCCCAATGCTGCAACAGCATCCTTTGGGGCTTTTAACTTTCCCCCCGCAGTAATGgCGCATCTCATGTACAATCACGGCGGCAATAGCCAGCACAGCCAGAGTGGCAGCGACACCGGCAAATAG
- Protein Sequence
- MHPSRAIAMASHYPHPQPDPDLKSETEPAGGMLVALDSIDADRVCRVCLKDASQDGEQHFIFAEGPLELGANLARILNECTLHPCERHDGMPSNMCGSCVEAARHAYRFKRNAERSYCSLVALLDRSPQLKSSGAEAGTQTDQVALLPCEMCHDQFLNSLELRLHRNRAHRTTTTTKEGTEGNDGAVGEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCGHCQRTFSRRDHLLRHMRNQHPRLEDDDLFHTWPPAADETTMQSSAGDELVSAEVLLNEKDEDHDEGDIFQCNTNPISSNEDEDNADDEDNVEAKQTLWLHIKPEPCLEAEEVSLATQLKLEKKRRRREKTEPRVASSSDSPVKHEPIAAVDAQLSIKQESQLVGSEDEAPMGVEEFISLHASRELPFSDEDHFGDYGDEESALDDDDDDEEEEEDDDDEDGDGDDGDFKLKVEPLDGDQSPKKKSKTKGRRRRRNKGEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSICEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLAAAAAAGVGTESTSSSTVIHSPEAYSSSNATAAAAAVAVAGTAAGAASTTLDGASFAPTPVPNAATASFGAFNFPPAVMAHLMYNHGGNSQHSQSGSDTGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00489505;
- 90% Identity
- iTF_00478145;
- 80% Identity
- -