Dboq017124.1
Basic Information
- Insect
- Drosophila bocqueti
- Gene Symbol
- -
- Assembly
- GCA_018151655.1
- Location
- JAECXF010000129.1:9004571-9007479[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.8 3.7e+02 1.9 0.9 2 23 140 162 139 162 0.92 2 13 0.0019 0.14 12.6 5.0 1 23 179 202 179 202 0.97 3 13 4.8e-06 0.00036 20.8 5.9 2 23 209 231 208 231 0.96 4 13 0.0096 0.73 10.4 9.1 2 23 471 492 471 492 0.97 5 13 1.7e-06 0.00013 22.2 2.9 1 23 498 521 498 521 0.95 6 13 0.0003 0.023 15.1 0.4 1 23 526 549 526 549 0.93 7 13 5.5e-05 0.0042 17.4 5.5 1 23 567 589 567 589 0.96 8 13 0.00022 0.017 15.5 0.6 1 23 594 616 594 616 0.98 9 13 2.9e-05 0.0022 18.3 1.7 1 23 622 644 622 644 0.95 10 13 2.1e-05 0.0016 18.8 0.7 1 23 650 672 650 672 0.98 11 13 3e-07 2.3e-05 24.6 2.7 3 23 680 700 679 700 0.99 12 13 2.2e-08 1.7e-06 28.1 1.1 1 23 706 728 706 728 0.99 13 13 0.33 25 5.5 3.4 1 19 733 751 733 756 0.89
Sequence Information
- Coding Sequence
- ATGGCGTCGACCTACCCGCACCCTCAGCCCGATCCGGGTCTCAAGTTCGAAACACAGCCGGCGGGCGGTATGTTGGTCGCCCTGGATTCCGTTGACGCGGACCGCGTATGCCGCGTTTGCCTTAAGGACGCTTCCCAGGACGGAGAGCTGCACTTCATCTTCGCGGACGGGCCACTGGAACTAGGCGCCAACTTGGCCCGCATCCTGGACGAGTGTACGCTGCATCCGTGCGAGCGACACGACGGGATGCCGTCAAACATGTGCGGCTCCTGCGTGGAGGCAGCCCGCCACGCCTACCGCTTCAAGCGCACCGCCGAGCGCTCCTACTGCTCCCTGGTGGCGCTGCTCGGCCGCTCCCCGCAGTTAAAGTCAAATGGCGCCGAGGCGGGTACCCAGACCGAGCAGGTGGCTCTGCTGCCCTGCGAGATGTGCCACGACCAGTTCCTCAACAGCCTGGAGCTGCGCCTGCACCGCAACCGGGTGCACAGGACGACGAAGGAGGGAACTGAGGGCAATGACGGCGCTGGCGAAGAATTCAAGTGCAAGTTTTGTCCGCAACACTTTCCGCATCTCCGACAGCTGCGCAGCCATTTGGCTCGTAGCCACGAGCAGACCGCTCACCTCCAGTGCGCCCACTGCCAGCGCACCTTCAGTCGCCGGGACCATCTGCTGCGTCACATGCGCAACAAACACCGACACCTGGAGGACGACATCTTCCAAACCTGGCCACCGGCGGACGAGACGACCATGCAGAGCTCCGTGGGCGATGAGCTCGTCTCTGCGGAAGTGCTCCTCAACGAGAAGGAAGACGACCACGACGAGGGCGACATTTTCCAAAGCAACACGAATCCCATTTCCAGCAACGAGGACGAGGACGACGATGAGGATAACGTAGAGGCTAAGCAGACACTGTGGCTGCACATCAAGCCGGAGCCCTGCCTGGAGCCCGAGGAAGTAAGCCTGGCCACGCAGCTGAAGCTCGAGAAGAAGCGACGGCGGCGGCGGGAGAAGGCGGAGTCGCGTGTCGCGAGCTCCAGTGATTCGCAGGTGAAACGTGAGCCCCTAGCCGTTGGCGACTCCCAACTTAGCATCAAGCAGGAAAGCCAGCTGGTGGGCAGCGAGGACGAGGCGCCAATGGGTGTGAAGGAGTTCATGGCGTTGCACGCCATGGGCGAACTGCCGCTCAGCGATGAGGACCATTTCGGAGACTATGGCGATGAGGAAAGCGCCCTGGACGACGACGATGACGAGGAGGAGGAGGACGAGGACGACGATGAGGATGGAGATGGGGACGACGGGGACTTCAAGCTGAAGGTGGAACCGCTGGACGGTGAGCAGCCGCCAAAGAAGTCCAAGTCCAAGTCTGGCAGGCGGCGGCGCCGAAACAAGAGTGAGCCCAATCCGGACAACCGGTGCGATGTGTGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCCCATCTGGAGAAGAAGCCCCACAACTGCCCGCACTGTCCCAAGGCGTTTGCGCGCAGCGACCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAATAAGGAGCACAAGTGCGGCATCTGCGAGGCGGCCTTCTCTCGCCTGGACGCCCTGGAGCGGCATAAGGTGAGCAAGCACAACGGCGAGGGCCTCGAGCCGGGCAGCGAGCTCAAGCTGCAGCTGGCCGAGCACACCTGCGAGTACTGCTCCAAGCGCTTCTCGAGCAAGACGTACTTGCGGAAGCACACGCTGCTGCACACCGATTTCCTCTACGCCTGCAAGAGCTGCGAGGAGACATTCCGCGAGCGCGCCCAGCTGCGGGAGCACGAAAAGACGCACACCGGGCAACGCAACTTCCTCTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTACCTCCGCGTCCATATGCGGCGCCACAACGGCGAGAAGCCCTACAAGTGCCGCTACTGTGTCAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTCCACGAGCGGTACCACACAAACACGAAACCGAACCTGTGCAATACCTGCGGCAAGAGCTTTCATCGGGCCTACAACCTCACCATTCACATGCGCACCCACACCGGCGAGCGACCGTACAAATGCGACCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCATATCCGCCGGCACACGGGCGAGCGGTACAAGTGTCCGCACTGCGACGCCTACTTCCTGCAGCTGTACAACATGCGCAACCACTGCCTGAGCGCCCACAACAAGCACATTGAGACGAAGACGGGACGCCTGCAGCGGACGGGCCTGCTGGACGATGGCGGGCAGTCGCATCTCACCACCGTTGTGATGCCGCCGTCACAGCTGGCAACGACAGCGGTCGCTGCTGGTACCGAGAGCACGTCCTCGTCCACGGTCATCCATTCGCCGGAGGCCTACAGCAGCAGCAATGCGACATCTGCGGGGCTGGTTCCGACACAAGCAGCAGCAGCAGCAGTTGCAGTGGCAGGAGGAGGAGCCGCGTCCACTACTCTCGATGGCGCCAGCTTTGCACCGACGCCGGTCAATGCGGCGGGAGCATCCTTTGGGGCTTTTAACTTTCCGCCCGCCGTAATGGCACATCTCATGTACAACCACGGCGGCAGCAGCCAGCACAGCCAGAGTGGCAGCGAGACGGGCAAATAG
- Protein Sequence
- MASTYPHPQPDPGLKFETQPAGGMLVALDSVDADRVCRVCLKDASQDGELHFIFADGPLELGANLARILDECTLHPCERHDGMPSNMCGSCVEAARHAYRFKRTAERSYCSLVALLGRSPQLKSNGAEAGTQTEQVALLPCEMCHDQFLNSLELRLHRNRVHRTTKEGTEGNDGAGEEFKCKFCPQHFPHLRQLRSHLARSHEQTAHLQCAHCQRTFSRRDHLLRHMRNKHRHLEDDIFQTWPPADETTMQSSVGDELVSAEVLLNEKEDDHDEGDIFQSNTNPISSNEDEDDDEDNVEAKQTLWLHIKPEPCLEPEEVSLATQLKLEKKRRRRREKAESRVASSSDSQVKREPLAVGDSQLSIKQESQLVGSEDEAPMGVKEFMALHAMGELPLSDEDHFGDYGDEESALDDDDDEEEEDEDDDEDGDGDDGDFKLKVEPLDGEQPPKKSKSKSGRRRRRNKSEPNPDNRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGICEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLATTAVAAGTESTSSSTVIHSPEAYSSSNATSAGLVPTQAAAAAVAVAGGGAASTTLDGASFAPTPVNAAGASFGAFNFPPAVMAHLMYNHGGSSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00489505;
- 90% Identity
- iTF_00478145;
- 80% Identity
- -