Dkik009657.1
Basic Information
- Insect
- Drosophila kikkawai
- Gene Symbol
- -
- Assembly
- GCA_018152535.1
- Location
- NW:3365660-3368951[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.2 3.1e+02 1.9 0.9 2 23 148 170 147 170 0.92 2 13 0.002 0.12 12.6 5.0 1 23 187 210 187 210 0.97 3 13 2.2e-05 0.0013 18.8 5.0 2 23 217 239 216 239 0.96 4 13 0.01 0.61 10.4 9.1 2 23 486 507 486 507 0.97 5 13 1.8e-06 0.00011 22.2 2.9 1 23 513 536 513 536 0.95 6 13 0.00032 0.019 15.1 0.4 1 23 541 564 541 564 0.93 7 13 5.8e-05 0.0035 17.4 5.5 1 23 582 604 582 604 0.96 8 13 0.00023 0.013 15.6 0.7 1 23 609 631 609 631 0.98 9 13 3.1e-05 0.0018 18.3 1.7 1 23 637 659 637 659 0.95 10 13 2.2e-05 0.0013 18.8 0.7 1 23 665 687 665 687 0.98 11 13 3.2e-07 1.9e-05 24.6 2.7 3 23 695 715 694 715 0.99 12 13 2.3e-08 1.4e-06 28.1 1.1 1 23 721 743 721 743 0.99 13 13 0.35 21 5.5 3.4 1 19 748 766 748 771 0.89
Sequence Information
- Coding Sequence
- ATGCACCCAGCAAGAGCTATAGCCATGGCATCCCACTACCCGCTCCCGCAGCCCGATCCGGGTCTCAAGTCCGAGACGCAGCCGGCGGGCGATAGGTTGGTCACCCTGGATGCCGTTGACGCGGACCGCGTCTGCCGCGTTTGCCTTAAGGACGCCTCCCAGGACGGCGAACTGCACTTCATCTTTGCGGACGGACCGCTGGAACTGGGCGCCAACTTGGCGCGCATCCTGGACGAGTGTACGCTGCATCCGTGCGAACGGCAAGATGGTATGCCGTCCAACATGTGCGGCTCCTGCGTGGAGGCAGCCCGCCACGCCTATCGCTTCAAGCGCAACGCCGAGCGCTCCTACTGCTCTCTGGTGGCGCTGCTAGGCCGCTCGCCGCAGTTAAAGTCCAATGGTGCCGAGGCGGGCACCCAGACCGACCAGGTGGCCCTGCTGCCCTGCGAGATGTGTCACGACCAGTTCCTCAACAGCTTGGAGCTGCGCCTGCACCGCAACCGGGTGCACAGGACAGCGAAGGATGGCACTGAAGGCAACGACGGTGCTGTCGAGGAATTTAAGTGCAAGTTCTGTCCGCAGCACTTCCCGCATCTCCGACAGCTGCGCAGTCACTTGGCACGCAGCCACGAGCAGACCGCTCGCCTTCAGTGCGCCCACTGCCTGCGCACCTTCAGTCGCCGGGATCATCTTCTGCGACACATGCGTAATCAGCACCGTCACTTGGAAGACGACCTCTTAAACACTTGGCCGCCGGCGGATGAGACCACCATGCAAAGCTCTGCGGGTGATGAGCTTGTCTCGGCGGAAGTGCTCCTTAGCGAGGAAAAGGATAACCCTGAGGATGGCGATATCTTCCAATGCAACACGAATCCCATTTCCAGCaacgaggaggacgacgacgacgatgaggaTAACTTAGAGGCTAAGCAGACACTGTGGCTGCACATCAAGCCAGAGCCCTGCCTAGAGACTGAGGAAGTTAGCCTGGCCACGCAACTGAAGCTGGAGAAgaagcagcggcggcggcggcggcgtggggAAAAGGCGGAGCCGCGTTTAGGGAGCTCCAGTGACTCGCCGGTGAAGCGTGAGCCCCTGGCCGCTGGCGACCCTCAACTCAGCATCAAGCAGGAGAGCCAGCTGGTGGGCAGCGAGGATGAGGCGCCCATGGGTGTGGAGGAGTTCATGGCACTGCATGCCACGGGAGAGCTGCCGTTTAGCGATGAGGAACATTTCGGTGActacggagacggagacgacGAAAGTGCTTtggatgacgacgacgaggaggaggaggacgatgacgacgacgatgaagaTGCAGATGGAAACGATGGGGATTTTAAGATGAAAATGGAGCCGCTGGACGGTGAGCAGCAGTCGCCCAAGAAGTGCAAGTCTGGCaggcggaggcggcggcgcCACAGCAAGGGCGAGCCCAATCCCGAAAACCGTTGCGATGTCTGCCAGCGCACCTTCTCGCGTCACTGCCACCTGCTGCGCCACAAGCTGTCCCACCTGGAGAAGAAGCCCCACAATTGCCCGCACTGTCCCAAGGCATTTGCGCGCAGCGATCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAACAAGGAGCACAAGTGCGGCATCTGCGAGGCGGCCTTCTCCCGTCTGGATGCCCTCGAGCGGCACAAGGTGAGCAAGCACAACGGCGAGGGCCTGGAGCCGGGCAGTGAGCTCAAGCTGCAGCTGGCGGAGCACACCTGCGAGTACTGCTCCAAGCGCTTCTCCAGCAAAACGTACTTGCGGAAGCACACCCTGCTGCACACGGACTTCCTCTACGCCTGCAAGAGCTGCGAGGAGACATTCCGCGAGCGCGGCCAGCTGCGAGAGCACGAGAAGACGCACACCGGGCAGCGCAACTTCCTTTGCTGCATTTGCGGCGATAGCTTTGCCCGGAATGACTACCTCCGTGTCCATATGCGGCGTCATAATGGTGAAAAGCCTTACAAGTGCCGCTACTGTGTGAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTCCACGAGCGCTATCACACAAACACGAAACCGAACCTGTGCAATACCTGCGGCAAGAGCTTTCACCGGGCCTATAACCTGACCATCCACATGCGCACCCACACCGGCGAGCGACCCTACAAGTGCGACCAGTGTCCCAAGAGCTTTACGCAGAGCAACGACCTCAAGGCTCACATCCGCCGGCACACGGGTGAGCGGTACAAGTGTCCTCACTGCGATGCCTACTTCCTGCAGTTGTACAACATGCGCAACCACTGTTTGAGTGCCCACAACAAGCACATTGAGACGAAGACGGGACGCCTGCAGAGGACAGGTCTGCTGGATGATGGTGGCCAGTCGCATCTCACCACCGTGGTGATGCCGCCATCACAGCTGGCAAcaacggctgctgctgctggcaccGAGAACACCACCTCTTCCACGGTTATACACTCGCCAGAAGGGTATAGCAGCAATGCGGGAGtggctggagcaggagcaggagcaggttCCACCACTCTGGATGGTGCCAGCTTTGCACCGACGCCAGTCAATGCCTCCTTTGGGGCTTTTAACTTTCCACCCGCTGTAATGGCTCATCTCATGTACAACCACGGCGGCACTAGCCAGCACAGTCAGAGTGGCAGCGACACGGGCAAATAG
- Protein Sequence
- MHPARAIAMASHYPLPQPDPGLKSETQPAGDRLVTLDAVDADRVCRVCLKDASQDGELHFIFADGPLELGANLARILDECTLHPCERQDGMPSNMCGSCVEAARHAYRFKRNAERSYCSLVALLGRSPQLKSNGAEAGTQTDQVALLPCEMCHDQFLNSLELRLHRNRVHRTAKDGTEGNDGAVEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCLRTFSRRDHLLRHMRNQHRHLEDDLLNTWPPADETTMQSSAGDELVSAEVLLSEEKDNPEDGDIFQCNTNPISSNEEDDDDDEDNLEAKQTLWLHIKPEPCLETEEVSLATQLKLEKKQRRRRRRGEKAEPRLGSSSDSPVKREPLAAGDPQLSIKQESQLVGSEDEAPMGVEEFMALHATGELPFSDEEHFGDYGDGDDESALDDDDEEEEDDDDDDEDADGNDGDFKMKMEPLDGEQQSPKKCKSGRRRRRRHSKGEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGICEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERGQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLATTAAAAGTENTTSSTVIHSPEGYSSNAGVAGAGAGAGSTTLDGASFAPTPVNASFGAFNFPPAVMAHLMYNHGGTSQHSQSGSDTGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00489505;
- 90% Identity
- iTF_00489505;
- 80% Identity
- -