Dbur004783.1
Basic Information
- Insect
- Drosophila burlai
- Gene Symbol
- -
- Assembly
- GCA_008042655.1
- Location
- VNJT01003051.1:108243-111187[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.3 4e+02 1.9 0.9 2 23 148 170 147 170 0.92 2 13 0.002 0.15 12.6 5.0 1 23 188 211 188 211 0.97 3 13 5.2e-06 0.0004 20.8 5.9 2 23 218 240 217 240 0.96 4 13 0.01 0.8 10.4 9.1 2 23 482 503 482 503 0.97 5 13 1.8e-06 0.00014 22.2 2.9 1 23 509 532 509 532 0.95 6 13 0.00033 0.025 15.1 0.4 1 23 537 560 537 560 0.93 7 13 5.9e-05 0.0045 17.4 5.5 1 23 578 600 578 600 0.96 8 13 0.00024 0.018 15.5 0.6 1 23 605 627 605 627 0.98 9 13 3.1e-05 0.0024 18.3 1.7 1 23 633 655 633 655 0.95 10 13 2.2e-05 0.0017 18.8 0.7 1 23 661 683 661 683 0.98 11 13 3.2e-07 2.5e-05 24.6 2.7 3 23 691 711 690 711 0.99 12 13 2.4e-08 1.8e-06 28.1 1.1 1 23 717 739 717 739 0.99 13 13 0.36 28 5.5 3.4 1 19 744 762 744 767 0.89
Sequence Information
- Coding Sequence
- ATGGACCCAGCAAGAGCTATAGCCATGGCGTCGACCTACCCGCACCCGCAGCCCGATCCGGGTCTCAAGTCCGAAACACAGCCGGCGGGCGGTATGTTGGTCTCCCTGGATTCCGTTGACGCGGATCGCGTATGCCGCGTTTGCCTTAAGGACGCTTCCCAGGACGGAGAGCTGCACTTCATCTTCGCGGACGGGCCACTGGAACTAGGCGCCAACTTGGCCCGCATCCTGGACGAGTGTACGCTACATCCGTGCGAGCGACACGACGGAATGCCGTCCAACATGTGCGGCTCCTGCGTGGAGGCAGCCCGCCACGCCTACCGCTTCAAGCGCACCGCCGAGCGCTCCTACTGCTCCCTGGTGGCGCTGCTCGGCCGTTCCCCGCAGTTAAAGTCGAATGGCGCCGAGGCGGGCACCCAGACCGAGCAGGTGGCCCTGCTGCCCTGCGAGATGTGCCACGACCAGTTTCTCAACAGCCTGGAGCTGCGCCTGCACCGCAACCGGGTGCACAGGACGACGAAAGAGGGAACTGAGGGCCGCAATGACGGCGCTGGCGAAGAATTCAAGTGCAAGTTTTGTCCGCAGCACTTCCCGCATCTCCGACAGCTACGCAGCCATTTGGCTCGTAGCCACGAGCAGACCGCTCGCCTCCAGTGCGCCCACTGCCAGCGCACCTTCAGTCGCCGGGATCATCTGCTGCGGCATATGCGCAACAAACACCGACACATGGAGGACGACATCTTTCAAACCTGGCCACCGGCGGACGAGACGACCATGCAAAGCTCCGTGGGCGATGAGCTCGTCTCTGCGGAAGTGCTCCTCAACGAGAAGGAAGACGACCACGACGAGGGCGGCGACATCTTCCAAAGCAACACGAATCCCATTTCCAGcaacgaggacgaggacgacgatgaGGATAACGTAGAGGCTAAGCAGACACTGTGGCTGCACATCAAGCCGGAGCCTTGCCTGGAGGCCGAGGAAGTGAGCCTGGCCACGCATCTAAAGCTCGAGAAGAAGCGACGGCGGCGGGAAAAGGCGGAGTCGCGTGTCGCGAGCTCCAGTGATTCGCAGGTGAAACGTGAGCCCCTAGCCGTTGGCGACTCCCAACTTAGCATCAAGCAGGAAAGCCAGCTGGTGGGCAGCGAGGACGAGGCGCCAATGGGTGTGAAGGAGTTCATGGCGTTGCACGCCATGGGAGAACTGCCGCTCAGCGATGAGGACCATTTCGGTGACTATGGCGACGACGAAAGTGCCCtagacgacgacgatgacgacgacgaggaggaggacgaggacgaggacgacgatggAGATGGGGACGACGGGGACTTTAAGCTGAAGGTGGAACCGCTGGAcggtgagcagcagcagccggcaaagtccaagtccaagtctgGCAGGCGGCGGCGCCGAAACAAGAGTGAGCCCAATCCGGACAACCGGTGCGATGTATGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCCCACCTGGAGAAGAAGCCCCACAACTGCCCGCACTGTCCCAAGGCGTTTGCGCGCAGCGACCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAATAAGGAGCACAAGTGCGGCATCTGCGAGGCGGCCTTCTCTCGTCTGGACGCCCTCGAGCGGCACAAGGTTAGCAAGCACAACGGCGAGGGCCTGGAGCCGGGCAGCGAGCTGAAGCTGCAGCTGGCCGAGCACACCTGCGAGTACTGCTCGAAGCGATTCTCCAGCAAGACGTACTTGCGGAAGCACACGCTGCTGCACACCGATTTCCTCTACGCCTGCAAGAGCTGCGAGGAGACATTCCGCGAGCGCGCCCAGCTGCGGGAGCACGAGAAGACGCACACCGGGCAACGCAACTTCCTCTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTACCTCCGCGTCCATATGCGGCGCCACAACGGCGAGAAGCCCTACAAGTGCCGCTACTGTGTCAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTCCACGAGCGGTACCACACAAACACGAAACCGAACCTGTGCAATACCTGCGGCAAGAGCTTTCATCGGGCCTACAACCTGACCATTCACATGCGCACCCACACCGGCGAGCGACCGTACAAATGCGACCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCATATCCGCCGGCACACGGGCGAGCGGTACAAGTGTCCGCACTGCGACGCCTACTTCCTGCAGCTGTACAACATGCGCAACCACTGCCTGAGCGCCCACAACAAGCACATTGAGACGAAGACGGGACGCCTGCAGCGGACGGGCCTGCTGGACGATGGCGGGCAGTCGCATCTTACCACCGTTGTGATGCCGCCATCACAGCTGgcggcagcgacagcggcCGAGAGCACGTCCTCGTCCACGGTCATCCATTCGCCGGAAGCGTACAGCAGCAATGCGACATCCGCGGGGCTGGTTCCgacacaagcagcagcagttgcaggagcaggagcaggagcggcgTCCACTACTCTTGATGGCGCCAGCTTTGCACCGACACCGGTCAATGCAGCGGGAGCATCCTTTGGGGCTTTTAACTTTCCGCCCGCCGTAATGGCACATCTCATGTACAACcacggcggcagcagccagcaCAGCCAGAGTGGCAGCGAAACGGGCAAATAG
- Protein Sequence
- MDPARAIAMASTYPHPQPDPGLKSETQPAGGMLVSLDSVDADRVCRVCLKDASQDGELHFIFADGPLELGANLARILDECTLHPCERHDGMPSNMCGSCVEAARHAYRFKRTAERSYCSLVALLGRSPQLKSNGAEAGTQTEQVALLPCEMCHDQFLNSLELRLHRNRVHRTTKEGTEGRNDGAGEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCQRTFSRRDHLLRHMRNKHRHMEDDIFQTWPPADETTMQSSVGDELVSAEVLLNEKEDDHDEGGDIFQSNTNPISSNEDEDDDEDNVEAKQTLWLHIKPEPCLEAEEVSLATHLKLEKKRRRREKAESRVASSSDSQVKREPLAVGDSQLSIKQESQLVGSEDEAPMGVKEFMALHAMGELPLSDEDHFGDYGDDESALDDDDDDDEEEDEDEDDDGDGDDGDFKLKVEPLDGEQQQPAKSKSKSGRRRRRNKSEPNPDNRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGICEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLAAATAAESTSSSTVIHSPEAYSSNATSAGLVPTQAAAVAGAGAGAASTTLDGASFAPTPVNAAGASFGAFNFPPAVMAHLMYNHGGSSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00489505;
- 90% Identity
- iTF_00478145;
- 80% Identity
- -