Dano012949.1
Basic Information
- Insect
- Drosophila anomelani
- Gene Symbol
- -
- Assembly
- GCA_035045905.1
- Location
- JAWNOO010000076.1:10630775-10633674[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.2 4.6e+02 1.9 0.9 2 23 148 170 147 170 0.92 2 13 0.002 0.18 12.6 5.0 1 23 187 210 187 210 0.97 3 13 2.6e-06 0.00023 21.7 5.6 2 23 217 239 216 239 0.96 4 13 0.01 0.92 10.4 9.1 2 23 473 494 473 494 0.97 5 13 1.8e-06 0.00016 22.2 2.9 1 23 500 523 500 523 0.95 6 13 0.00033 0.029 15.1 0.4 1 23 528 551 528 551 0.93 7 13 5.9e-05 0.0052 17.4 5.5 1 23 569 591 569 591 0.96 8 13 0.00024 0.021 15.5 0.6 1 23 596 618 596 618 0.98 9 13 3.1e-05 0.0027 18.3 1.7 1 23 624 646 624 646 0.95 10 13 2.2e-05 0.002 18.8 0.7 1 23 652 674 652 674 0.98 11 13 3.2e-07 2.8e-05 24.6 2.7 3 23 682 702 681 702 0.99 12 13 2.3e-08 2.1e-06 28.1 1.1 1 23 708 730 708 730 0.99 13 13 0.35 32 5.5 3.4 1 19 735 753 735 758 0.89
Sequence Information
- Coding Sequence
- ATGCACCCATCAAGAGCAATAGCCATGGCGTCGCACTACCCGCGCCCGCAGCCCGATCCGGGTCTCAAGTCCGAGACGCAGGCGGGTGGCGGTATGTTGGTCCCCCTGGATTCCGTTGACGCGGACCGCCTCTGCCGCGTTTGCCTTAAGGACGCTTCAGAGGACGGAGAGCTGCACTTCATCTTCGCGGACGGGCCATTGGAGCTGGGCGCCAACTTGGCGCGCATCCTGGACGAGTGTACGCTACATCCGTGCGAGCGACACGACGGTATGCCGTCAAACATGTGCGGCTCCTGCGTAGAGGCAGCCCGCCACGCCTATCGCTTTAAGCGCAATGCCGAGCGGTCCTACTGCTCCCTGGTGGCACTGCTCGGACGCTCCCCGCAGTTAAAGTCAAATGGCGCCGAGGCAGGCACCCAGACCGACCAAGTGGCCCTCCTGCCCTGCGAGATGTGCCACGACCAATTTCTTAACAGCCTGGAGCTGCGCCTGCACCGCAACCGGGTGCACAGGACAACGAAGGAGGGCACTGAAGGCAACGACGGAGCCGGCGAGGAATTCAAGTGCAAGTTCTGTCCGCAGCACTTCCCGCACCTTCGTCAGCTACGCAGCCACTTGGCGCGCAGCCACGAGCAGACCGCTCGCCTCCAGTGCGGCCATTGCCAGCGCACCTTCAGTCGCCGGGATCATTTGTTGCGACACATGCGCAACCAGCACAGACACCTGGAAGCCGACATCTTCCAAACTTGGCCGCCGGCGGATGAGACGACCATGCAAAGCTCTGCGGGCGATGAGCTCGTCTCTGCGGAAGTTCTCCTCAACGAGAAGGAAGACGACCACGACGAGGGCGACATCTTCCAATGCAACACGAATCCCATTTCCAgcaacgaggacgaggacgacgatGAGGATAACGTAGAGGCTAAGCAAACACTATGGCTGCACATCAAGCCGGAGCCCTGTCTGGAGGCTGAGGAAGTTAATCTGGCCACGCAGCTAAAGCTTGAGAAGacgcggcggcggcgggaGAAGGCAGAGCCGCGTGTTGCGAGCTCCAGTGATCCACCGGTGAAACGTGAACCCATAGCTGCTGTCGACTCCCAACTTAGCATCAAGCAGGAAAGCCAGCTGGTGGGAAGCGAGGACGAGGCGCCTATGGGTGTGGAGGAGTTCATGGCGTTGCACAACACGAGAGAACTGCCGTTCAGCGATGAGGATAATTTCGGGGACTATGGCGATGACGAAAGTGCCCTggaagacgacgacgatgaggacGAGGATGACGATGAGGATGGAGACGGGGACGATGGAGACTTCAAGCTGAAAGTGGAGCCGCTGGACGGTGACCAGCCGCCAAAGAAGTCCAAGTCTGGCAGGCGAAGACGCCGAAACAAGGGCGAGCCCAATCCAGAAAACCGGTGCGATGTATGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCCCACCTGGAGAAGAAGCCCCACAACTGCCCGCACTGTCCCAAGGCGTTTGCGCGCAGCGATCACCTCAAGGCGCATGTCCAGAGCCTGCATAGCAATAAGGAGCACAAGTGCGGCATCTGCGAGGCGGCCTTCTCCCGCCTGGACGCTCTGGAGCGGCACAAGGTTAGCAAGCACAACGGCGAGGGCCTTGAGCCGGGCAGCGAGCTTAAGCTGCAGCTGGCCGAGCACACCTGCGAGTACTGCTCCAAGCGTTTCTCCAGCAAAACGTACTTGCGGAAGCATACGCTGCTGCACACCGATTTCCTCTATGCCTGCAAGAGCTGCGAGGAGACATTCCGCGAGCGTGCCCAGCTGCGGGAGCACGAAAAGACGCACACTGGGCAACGCAACTTCCTCTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTACCTCCGCGTCCATATGCGGCGCCACAACGGCGAGAAGCCCTACAAATGCCGCTACTGTGTCAAGGCCTTTCCGCGGGCCACCGATCTCAAGGTCCACGAGCGGTACCACACAAACACGAAACCGAATCTGTGCAATACTTGCGGCAAGAGCTTTCACCGGGCCTATAACCTGACCATTCACATGCGCACTCACACCGGCGAGCGACCGTACAAATGCGACCAGTGCCCCAAGAGCTTTACGCAGAGCAACGACCTCAAGGCGCACATCCGCCGGCACACGGGCGAGCGGTACAAGTGCCCGCACTGTGACGCCTACTTTCTGCAGCTATACAACATGCGCAACCACTGCCTGAGCGCCCACAACAAGCACATTGAGACGAAGACGGGACGCCTGCAGCGAACGGGTCTGCTGGACGATGGCGGCCAGTCGCATCTCACCACGGTTGTGATGCCACCGTCACAGCTGGCAACGGCTGCGGCCGCTGGAACCGAGAGCACGTCCTCGTCCACGGTCATCCACTCACCGGAACCCTACAGCAGCAATGCCACATCCGCCGGGCTGGCTCCGACAGCagtagcaggagcaggagcaggagcggcgTCCACTACTCTCGATGGCGCCAGTTTTGCACCGACGCCGGTCAATACGGCGGCAGCATCCTTTGGGGCTTTTAACTTTCCGCCCGCAGTAATGGCGCATCTCATGTACAATCACGGCGGCAGTAGCCAGCACAGCCAGAGTGGCAGCGACACGGGCAAATAG
- Protein Sequence
- MHPSRAIAMASHYPRPQPDPGLKSETQAGGGMLVPLDSVDADRLCRVCLKDASEDGELHFIFADGPLELGANLARILDECTLHPCERHDGMPSNMCGSCVEAARHAYRFKRNAERSYCSLVALLGRSPQLKSNGAEAGTQTDQVALLPCEMCHDQFLNSLELRLHRNRVHRTTKEGTEGNDGAGEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCGHCQRTFSRRDHLLRHMRNQHRHLEADIFQTWPPADETTMQSSAGDELVSAEVLLNEKEDDHDEGDIFQCNTNPISSNEDEDDDEDNVEAKQTLWLHIKPEPCLEAEEVNLATQLKLEKTRRRREKAEPRVASSSDPPVKREPIAAVDSQLSIKQESQLVGSEDEAPMGVEEFMALHNTRELPFSDEDNFGDYGDDESALEDDDDEDEDDDEDGDGDDGDFKLKVEPLDGDQPPKKSKSGRRRRRNKGEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGICEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTNTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPSQLATAAAAGTESTSSSTVIHSPEPYSSNATSAGLAPTAVAGAGAGAASTTLDGASFAPTPVNTAAASFGAFNFPPAVMAHLMYNHGGSSQHSQSGSDTGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00489505;
- 90% Identity
- iTF_00561891; iTF_00492365; iTF_00593966; iTF_00541202; iTF_00613622; iTF_00485280; iTF_00594679; iTF_00488793; iTF_00491641; iTF_00524542; iTF_00490208; iTF_00612939;
- 80% Identity
- -