Dbia002525.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila biarmipes
Gene Symbol
-
Assembly
GCA_018148935.1
Location
JAECYG010000079.1:8426487-8429084[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.013 0.75 10.1 3.7 3 23 277 297 275 297 0.97
2 12 0.00054 0.032 14.5 0.7 1 23 303 328 303 328 0.94
3 12 0.022 1.3 9.4 0.1 5 23 341 360 340 360 0.95
4 12 6.9e-05 0.0041 17.3 1.3 1 23 372 394 372 394 0.98
5 12 1.9e-06 0.00012 22.1 0.1 1 23 401 423 401 423 0.98
6 12 0.012 0.74 10.2 0.2 1 23 429 451 429 451 0.97
7 12 0.066 3.9 7.9 3.0 1 23 457 480 457 480 0.97
8 12 0.01 0.62 10.4 4.4 1 23 486 508 486 508 0.96
9 12 0.1 6.2 7.3 5.3 2 23 515 536 514 536 0.96
10 12 0.00012 0.0069 16.6 0.2 1 23 651 674 651 674 0.95
11 12 0.1 5.9 7.3 1.3 1 21 680 699 680 702 0.75
12 12 5.9e-07 3.5e-05 23.8 3.4 1 23 708 730 708 730 0.98

Sequence Information

Coding Sequence
ATGAACGAGGGCAGGCAGTACTCGATCCACAGCCTGTGCAGGATCTGCCTGAACCACCTGCAGAACGACGCCGCCTACGATTTGTATCTGGTGCCAGGACTCTCCAAGAAGCTCTGCTTCTGCACATCCCTGTCCGTGGAGCAGAACGACGGCTTCCCGAAGAACCTGTGCACCCTGTGCTACACCAAGCTGAACGAGCTGCACGACTTTCAGAGGCAGTGCGTCGACTCAGTGCAAAAGTTCCAGGACCTGGTGGCCAGCAATGTCTTCACCTGCCAGAGCAACTTCGACGTCCTGGATCCCAATGTTGCCGTGCAGGACTACCAGGGCGAGGAAGAGGACCACGTCAACTATGATCCCCTGCTGAACCACAAGATGGAGCTGATCGAGAACGAGGAGGATGTCTTCAAGATGCTGGAGCACGTCGACAAGGAGGCCGAGGAGGTGGAGAACGGAACCAAGGTGGAGGAGGATGACAAGGCCAACGTCTCCATCAAGATGTTCGACGAAGAATCCTCCATCGAGAGCGGCAACGACAACGACCACGACCTGGACTTCGAGCCGAACAGCAGCGATGATGACATTCCGCTGGCCCAGCGCATGCGGGGACCAGCTACCGGACCAGGATCCAGCTCGGCCAGCCAAAACAAACCCAAACCGAAGCCCAGGGGACGACCCAAGAAGATAAAGCCGCCGCCACCGGACGAGGAGGAAATAAGCGGCTCTTCGTCCGAGTCGGATGACTCCGAGGACGGCAATTCGCGCGGAGACAAACCGAAGAGGAAGCGCATCCCAATCGAGGAGCGCCACTTGCACCGCATCATCGACTGCCACATCTGCCACCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAACGACCTGCTGCCCTTCCAGTGCAAGGTGGAGACCTGCAAGAAAGGTTTCACCACCGCCAACGGGCTGCGCATCCACATCGACCACGCCCACACGGAGCTGTCCGAGGTACATGCCTGCATCGCCGAGGGCTGCGGCAAGACCTTCCCGCGCGTCCGCCTACTGACCTTCCACATGAAGAAGGTCCACGGCATTACCAAGGCGGCGGCCCCGCTGCGCGACTTCCCCTGTCCGGAATGCGACACTGTCTTCCGCTGCCCCACGGCGCTGAAGAAGCACATGTACAAGCACACGGGTGAGGAGCTGCCGTACCCATGCAACATCTGCGGCAAGCGGTTTGTGATCAACAGTGCTTTAAGGGATCACCTAATGCGACATGCGGGCATCAAGAACCACGTGTGCCCCTACTGCGGAGTGGGCAAGACGACGCGACAGGAGTGGAACGCCCACATTCTTACACACACCAAGGAGAAGAAGTTTAAGTGCCGGCAGTGCGACCACGCCTCGCACAACAAACAGGCTCTGTCCAATCACGTCAAGGTGGTGCACGAGAAGCGCAAGGACTTCGCCTGCCAGTACTGCGGCAAGACCTTCGGCAAGAGCCACGCCTGCAAGGTACACGAGAGGAGCCACACCGGAGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATTTTCCTTTGCGAGAAGAGCCTCACCAAGCATTTGAAGACACACGAGAAACGGGATCTGCCGCCGGCGGAGCCCCTTCGCCAGCAGCTCAACATTCCCATGCCCGGCCAGATGCCCGGTCAGATGCCTGGGCAGATGCCGGGCCAGATGCCCATGCAAATGCAGGCCGATGGTTTGGTTCCGATGGACCCCAATCAGATGCCCAATGAGGACATGCTTAAGGCGTGCGGCGGCGGGCCCGCTGCAGTGCCTCCCAAGCCGAAGAACTCACGACGCGTCCAACGGGTGGACATCTCCCAATTGGCCGGCACCGCAGTGAATCCCATACCTTCCGTCTCCGTGCCCTCGTGGTCGCCGCAGGTGAACTTCACCAAGAAAGAGGGACAGCACATCTGTCCCGGCTGCGGACGTGGCTTTAACAACATTGGAAACATGAAACTCCACTACAAGATCATCCACGAAAAGGTCAAGGACTTCGCCTGTCGGTTCTGCCCCAAGAGATTCTCCAAGGCGCAGATTCTGCGCCACCACGAGTGGATCCACACCGGGGAGAAGCCCTTCGAGTGCAAGCTGTGCGGCAAGCACTTCCGCCAGGAGACGGCGCTCAAGAAGCACATCAAGACGCACGAGAAGCCCAACAGGAGGCACGTGCCCGAGCGCAGTGCGCCCACCCAGATCACGTTCCGCAAGCTGGAGCCGGATGCCGAGCCGCGGAACTTCGACCAGTACCAGGATCCGGCGGTGGAGCGGGCGGCGGCCACAGCCGAGCTGCTGGCGCACCAGCTGGAGGAGAACGAGGCCAAGCGGAAGGCGGACATCGAGCGGCAGAAGATCGCGGCGGCGGCCTGCGAGCAGCTGACGAAGCTGCAGCAGCAGCAGGAGATTATGAAGGCCACCACCTCGTACGATGGCTACTACGCGCAGAAGGCCCAGGCCGAGGGCACCAGCATGGACGCCCTGAAGATAGACCATGTCTAG
Protein Sequence
MNEGRQYSIHSLCRICLNHLQNDAAYDLYLVPGLSKKLCFCTSLSVEQNDGFPKNLCTLCYTKLNELHDFQRQCVDSVQKFQDLVASNVFTCQSNFDVLDPNVAVQDYQGEEEDHVNYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVENGTKVEEDDKANVSIKMFDEESSIESGNDNDHDLDFEPNSSDDDIPLAQRMRGPATGPGSSSASQNKPKPKPRGRPKKIKPPPPDEEEISGSSSESDDSEDGNSRGDKPKRKRIPIEERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHGITKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPAEPLRQQLNIPMPGQMPGQMPGQMPGQMPMQMQADGLVPMDPNQMPNEDMLKACGGGPAAVPPKPKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKLCGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNFDQYQDPAVERAAATAELLAHQLEENEAKRKADIERQKIAAAACEQLTKLQQQQEIMKATTSYDGYYAQKAQAEGTSMDALKIDHV