Basic Information

Insect: Drosophila prostipennis
Gene Symbol: -
Assembly: GCA_037075205.1
Location: JBAMCJ010000409.1:399088-401693[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.013 1.1 10.1 3.7 3 23 279 299 277 299 0.97

2 12 0.00058 0.045 14.5 0.7 1 23 305 330 305 330 0.94

3 12 0.023 1.8 9.4 0.1 5 23 343 362 342 362 0.95

4 12 7.4e-05 0.0058 17.3 1.3 1 23 374 396 374 396 0.98

5 12 2.1e-06 0.00016 22.1 0.1 1 23 403 425 403 425 0.98

6 12 0.013 1 10.2 0.2 1 23 431 453 431 453 0.97

7 12 0.071 5.6 7.9 3.0 1 23 459 482 459 482 0.97

8 12 0.011 0.88 10.4 4.4 1 23 488 510 488 510 0.96

9 12 0.11 8.8 7.3 5.3 2 23 517 538 516 538 0.96

10 12 0.00012 0.0098 16.5 0.2 1 23 653 676 653 676 0.95

11 12 0.11 8.4 7.3 1.3 1 21 682 701 682 704 0.75

12 12 1.7e-07 1.3e-05 25.6 3.0 1 23 710 732 710 732 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.013	1.1	10.1	3.7	3	23	279	299	277	299	0.97
2	12	0.00058	0.045	14.5	0.7	1	23	305	330	305	330	0.94
3	12	0.023	1.8	9.4	0.1	5	23	343	362	342	362	0.95
4	12	7.4e-05	0.0058	17.3	1.3	1	23	374	396	374	396	0.98
5	12	2.1e-06	0.00016	22.1	0.1	1	23	403	425	403	425	0.98
6	12	0.013	1	10.2	0.2	1	23	431	453	431	453	0.97
7	12	0.071	5.6	7.9	3.0	1	23	459	482	459	482	0.97
8	12	0.011	0.88	10.4	4.4	1	23	488	510	488	510	0.96
9	12	0.11	8.8	7.3	5.3	2	23	517	538	516	538	0.96
10	12	0.00012	0.0098	16.5	0.2	1	23	653	676	653	676	0.95
11	12	0.11	8.4	7.3	1.3	1	21	682	701	682	704	0.75
12	12	1.7e-07	1.3e-05	25.6	3.0	1	23	710	732	710	732	0.98

Sequence Information

Coding Sequence: ATGAACGAGGGCAGGCAGTACTCGATCCACAGCCTGTGCAGGATCTGTCTGAACCACCTGCAGAACGACGCCGCCTACGATTTGTATCTGGTGCCAGGACTCTCGAAGAAGCTCTGCTTCTGCACCTCCCTGTCCGTGGAGCAGAACGACGGCTTCCCGAAGAACCTGTGCACGCTGTGCTACACCAAACTCAATGACCTGCACGACTTCCAGAGGCAGTGCGTCGACTCGGTGCAAAAGTTCCAGGATCTGGTCGCCAGCAATGTCTTCGCCTGCCAGAGCAGCTTCGATGTCCTCGATCCCAATGTCGCCGTTCAGGACTACCAGGGCGAGGACGAGGATCACGTCAACTACGATCCCCTGCTGAATCACAAGATGGAGCTGATCGAGAACGAGGAGGATGTCTTCAAGATGCTGGAGCATGTGGACAAGGAGGCCGAGGAGGTGGAGAACGGCGCCAAGGTGGAGCGCGAGGACCCGGACGACGACGTGTCCATCAAGATGTTCGACGACGACTCCTCCATGGAGAGCGGCAACGACAACGACCACGACCTCGATTTCGAGCCCAACAGCAGCGATGATGACATTCCGCTGGCCCAACGCATGCGGGGACCAGCTACAGGAGCATCCGGATCTGGTTCCCATCTAGCCAGCAAGCCCAAAGCGAAGCGGGGACGCCCGAAGAAGATaaagccgccgccgccagaCGAGGAGGACATCAGTGGCTCCTCCGAGGACTCCGACGATGACTCCGAGGGCGGGACATCGCGTGGCGACAAGCCCAAGCGGAGGCGCATTCCCATGGAGGAGCGCCACCTGCACCGCATCATCGACTGCCACATCTGCCACCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAACGACCTGCTGCCCTTCCAGTGCAAGGTGGAGACCTGCAAGAAGGGTTTCACCACCGCCAACGGGCTGCGCATCCACATCGACCACGCCCACACGGAGCTGTCCGAGGTGCATGCCTGCATCGCCGAGGGCTGCGGCAAGACCTTCCCGCGCGTCCGCCTGCTCACCTTCCACATGAAGAAGGTGCACGGCATCACCAAGGCGGCCGCCCCGCTGCGCGACTTCCCCTGTCCCGAATGCGACACCGTCTTCCGCTGTCCCACGGCGCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCCTATCCCTGCAACATCTGCGGCAAGCGGTTTGTGATCAACAGTGCTTTAAGGGATCACCTCATGCGGCATGCGGGCATCAAGAACCATGTGTGTCCGTACTGCGGCGTGGGCAAGACGACGCGACAGGAGTGGAACGCCCACATCCTCACGCACACCAAGGAGAAGAAGTTCAAGTGCCGGCAGTGCGACCACGCCTCGCACAACAAACAGGCTCTGTCCAATCACGTGAAGGTGGTGCACGAGAAGCGCAAGGACTTCGCCTGCCAGTACTGTGGAAAGACCTTCGGCAAGTCGCACGCCTGCAAGGTGCACGAGAGGAGCCACACCGGGGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATCTTCCTCTGCGAGAAGAGCCTCACCAAGCATTTGAAGACACACGAGAAGAGGGATCTGCCGCCGGCGGAGCCCCATCGCCAGCAGCTTAACATTCCCATGCCCGGCCAAATGCCCGGTCAGATGCCCGGCCAGATGCCCGGTCAGATGCCCATGCAGATGCAGACCGACGGCTTGGTTCAGATGGATCCCCATCAGATGCCCAGTGAGGACATGCTCAAGGCGTGCGGCGGCGGGTCCGCTGCAGTGCCTCCCAAGCCGAAGAACTCACGGCGCGTCCAGAGGGTGGACATTTCCCAGCTGGCCGGCACCGCAGTGAATCCGATACCTTCCGTCTCCGTGCCCTCGTGGTCGCCGCAGGTGAACTTCACCAAGAAGGAGGGCCAGCACATCTGTCCCGGCTGCGGACGCGGCTTTAATAACATCGGTAACATGAAGCTCCACTACAAGATCATCCACGAGAAGGTCAAGGACTTTGCCTGTCGCTTCTGCCCCAAACGGTTCTCCAAGGCGCAGATCCTGCGCCACCACGAATGGATCCACACAGGCGAAAAGCCGTTCGAGTGCAAGATCTGCGGCAAGCACTTCCGCCAGGAGACGGCGCTCAAGAAGCACATCAAGACGCACGAGAAGCCGAACCGCAGGCACGTGCCCGAGCGCAGTGCGCCCACACAGATCACGTTCCGCAAGCTGGAGCCGGATGCCGAGCCGCGGAACTTCGATCAGTACCAGGATCCGGCGGTGGAGCGGGCGGCGGCCACCGCCGAGCTGCTGGCCCACCAGCTGGAGGAGAACGAGGCCAAGCGGAAGGCGGACATCGAGAGGCAGAAGATCGCGGCGGCGGCCTGCGAGCAGCTGAcgaagctgcagcagcagcaggagattATGAAGGCCACCACTTCGTACGACGGCTACTATGCGCAGAAGGCCCAGGCCGAGGGCACCACCTTGGACTCCCTGAAGATCGACCATGTCTAG
Protein Sequence: MNEGRQYSIHSLCRICLNHLQNDAAYDLYLVPGLSKKLCFCTSLSVEQNDGFPKNLCTLCYTKLNDLHDFQRQCVDSVQKFQDLVASNVFACQSSFDVLDPNVAVQDYQGEDEDHVNYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVENGAKVEREDPDDDVSIKMFDDDSSMESGNDNDHDLDFEPNSSDDDIPLAQRMRGPATGASGSGSHLASKPKAKRGRPKKIKPPPPDEEDISGSSEDSDDDSEGGTSRGDKPKRRRIPMEERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHGITKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPAEPHRQQLNIPMPGQMPGQMPGQMPGQMPMQMQTDGLVQMDPHQMPSEDMLKACGGGSAAVPPKPKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNFDQYQDPAVERAAATAELLAHQLEENEAKRKADIERQKIAAAACEQLTKLQQQQEIMKATTSYDGYYAQKAQAEGTTLDSLKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486750;
90% Identity: iTF_00504861;
80% Identity: -