Dkan004546.1
Basic Information
- Insect
- Drosophila kanapiae
- Gene Symbol
- -
- Assembly
- GCA_008042475.1
- Location
- VNJM01002088.1:491037-493675[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.012 0.94 10.1 3.7 3 23 287 307 285 307 0.97 2 12 0.0005 0.04 14.4 0.7 1 23 313 338 313 338 0.94 3 12 0.0017 0.14 12.8 1.1 1 23 345 370 345 370 0.96 4 12 6.5e-05 0.0052 17.2 1.3 1 23 382 404 382 404 0.98 5 12 1.8e-06 0.00015 22.1 0.1 1 23 411 433 411 433 0.98 6 12 0.012 0.92 10.1 0.2 1 23 439 461 439 461 0.97 7 12 0.061 4.9 7.9 3.0 1 23 467 490 467 490 0.97 8 12 0.0098 0.78 10.4 4.4 1 23 496 518 496 518 0.96 9 12 0.097 7.8 7.2 5.3 2 23 525 546 524 546 0.96 10 12 0.00011 0.0086 16.5 0.2 1 23 665 688 665 688 0.95 11 12 0.093 7.4 7.3 1.3 1 21 694 713 694 716 0.75 12 12 1.5e-07 1.2e-05 25.5 3.0 1 23 722 744 722 744 0.98
Sequence Information
- Coding Sequence
- ATGGACGTGGCGCGCACCTACTCGATCCACAGCCTGTGCAGGATCTGCCTGAACCACCTGCAGAACGACGCCGACTTGTACGACTTGTATCTGGTGCCAGGACTGGCCAAGAAGCTCTGCTTTTGCACCTCGCTTTCAGTGGAGCAGAACGATGGTTTCCCCAAGAACCTGTGTACCCAGTGCTACTCAAAGCTCACAGAGCTGCACGACTTCCAGCGACTGTGCGTGGACTCGGTGCAGAAGTTCCAGGATCTGGTCGCCAGCAACGCCTTTGCCTGCCAGACCAACTTCGATGTACTGGACCCCAGTGTGACAGTGCACGACATGCacggcgaggaggaggagaacaTCAACTATGACCCACTGCTGAACCACAAGATGGAGCTGATCGAGAACGAGGAGGACGTCTTCAAGATGCTGGAGCACGTGGACAAGGAGGCCGAGGAGGTGGAGAACGGCACCAAgcaagaggaggaggacgacaaGGCCGGCGTCAGCCACATCAAGATGTTCGACGACGACTCCTCTATCGAGAGtggcaacgacaacgaccGCGATCTGGATTTCGAGCCCAacagcagcgacgacgacatTCCGCTGGCCCAGCGCCTGCGTGGACCTGGCCCAGGAACATCCCAGCAAACAGTCCGCCAGGGCACCTACAACAAGGCGAAGGGCAAGCCTAGGGGCAGGCCCAAGAAGGtgaagccaccgccgccggacGACGAGGAGTCCACCAGCGCCTCCGACGACTCGGAGGATGACTCGGACGACAACAACCCAGACGGAACGCCCAGGGACAAACCGAAAAGGAAGCGCATTCCCGCCGACGAGCGCCACCTGCACCGCATCATCGACTGCCACATCTGCCACCAGAAGTTCAAGAAGGCCATTCGCTACGAGGAGCACATGAAGTACCACAACGACCTGCTGCCCTTCCAGTGCAAGGTGGAGACTTGCAAGAAAGGCTTCACCACGGCCAACGGCCTGCGCATCCACATCGACCACGCCCACACCGAACTGTCGGAGGTGCACACCTGCACCGCCGAGGGCTGCGGCAAGACCTTCCCCCGCGTCCGTCTGCTCACCTTCCACATGAAGAAGGTGCACGGACTGACCAAGGCGGCGGCGCCGCTGCGTGACTTCCCCTGCCCGGAGTGCGACACGGTCTTCCGCTGCCCCACGGCCCTGAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCGTATCCCTGCAACATTTGCGGCAAGCGGTTCGTGATCAACAGCGCCCTGAGGGATCACTTGATGCGGCACGCGGGCATCAAGAACCACGTCTGCCCCTACTGCGGTGTGGGCAAGACAACGCGCCAGGAGTGGAACGCCCACATCCTCACGCACACCAAGGAGAAGAAGTTCAAGTGCCGACAGTGCGACCACGCCTCCCACAACAAACAGGCCTTGTCCAACCACGTCAAGGTGGTGCACGAGAAGCGCAAGGACTTCGCCTGCCAGTACTGCGGCAAGACTTTCGGCAAGTCGCACGCCTGCAAGGTGCACGAGCGGAGCCACACCGGGGAGAAGTGCTGCGAGTGCAAAATCTGCGGCAAGATCTTCCTCTGCGAGAAGAGCCTAACCAAGCACCTGAAGACGCACGAGAAGCGCGATCTCCCGCCGTCGGAGCCGCACCGCCAGCAACTGAACATTCCGATGCCCGGCCAGATGGCGGGCCAAATGCCCGGCCAGATGCCGATGCAGATgcagggccagggccagggcgGCGACGGCCTGCTGCAGATGCAGGGCCAGGGTCCCAGCCAGATACCCAGTGACGACATGATGAAGGCGTGCGGCGGCGGGTCCGCTGCAGTGCCTTCAAAGCCGAAGAACTCTCGCCGCGTCCAGCGGGTAGACATTGCTCAGCTGGCGGGCACCGCCGTCAACCCCATTCCCTCAGTATCGGTGCCCTCGTGGTCGCCGCAGGTGAACTTCACCAAGAAGGAGGGCCAGCACATCTGCCCGGGTTGCGGGCGCGGCTTCAACAACATCGGAAACATGAAGCTTCACTACAAGATCATCCACGAGAAGGTAAAGGACTTTGCCTGCCGCTTCTGCCCCAAGCGGTTCTCCAAGGCGCAGATCCTGCGCCACCACGAATGGATCCACACCGGCGAGAAGCCCTTCGAGTGCAAGATCTGCGGCAAGCATTTCCGCCAGGAGACGGCGCTTAAGAAGCACATCAAGACGCACGAGAAGCCCAACCGCCGGCACGTGCCCGAGCGCAGTGCGCCCACCCAGATCACGTTCCGCAAGCTAGAGCCGGACGCCGAGCCGCGCAACTTCGATCAGTACCAGGACCCGGCGGTGGAGCGGGCGGCGGCCACCGCCGAGCTGCTGGCCCACCAGCTAGAGGAGAACGAGGCCCGGCGGAAGGCAGACATCGAGCGGCAAAAGATAGCGGCCGCCGCCTGCGAGCAGCTAAataagctgcagcagcagcaggacattATCAAGGCGACCACCTCGTACGACGGCTACTACGCGCAGAAGGCCCAGGCCGAGGGCACCAGCATCGATGCCCTGAAGATCGACCATGTCTAG
- Protein Sequence
- MDVARTYSIHSLCRICLNHLQNDADLYDLYLVPGLAKKLCFCTSLSVEQNDGFPKNLCTQCYSKLTELHDFQRLCVDSVQKFQDLVASNAFACQTNFDVLDPSVTVHDMHGEEEENINYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVENGTKQEEEDDKAGVSHIKMFDDDSSIESGNDNDRDLDFEPNSSDDDIPLAQRLRGPGPGTSQQTVRQGTYNKAKGKPRGRPKKVKPPPPDDEESTSASDDSEDDSDDNNPDGTPRDKPKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHTCTAEGCGKTFPRVRLLTFHMKKVHGLTKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPSEPHRQQLNIPMPGQMAGQMPGQMPMQMQGQGQGGDGLLQMQGQGPSQIPSDDMMKACGGGSAAVPSKPKNSRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNFDQYQDPAVERAAATAELLAHQLEENEARRKADIERQKIAAAACEQLNKLQQQQDIIKATTSYDGYYAQKAQAEGTSIDALKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00486750;
- 90% Identity
- iTF_00483135;
- 80% Identity
- -