Dmal014055.1
Basic Information
- Insect
- Drosophila malerkotliana
- Gene Symbol
- -
- Assembly
- GCA_018153235.1
- Location
- JAECXV010000067.1:21436792-21439343[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.011 0.77 10.2 3.7 3 23 278 298 276 298 0.97 2 12 0.00045 0.033 14.5 0.7 1 23 304 329 304 329 0.94 3 12 0.00078 0.057 13.7 0.3 1 23 336 361 336 361 0.95 4 12 5.8e-05 0.0043 17.3 1.3 1 23 373 395 373 395 0.98 5 12 1.6e-06 0.00012 22.2 0.1 1 23 402 424 402 424 0.98 6 12 0.01 0.76 10.2 0.2 1 23 430 452 430 452 0.97 7 12 0.055 4.1 7.9 3.0 1 23 458 481 458 481 0.97 8 12 0.0088 0.64 10.4 4.4 1 23 487 509 487 509 0.96 9 12 0.72 53 4.4 4.6 2 23 516 537 515 537 0.93 10 12 9.7e-05 0.0071 16.6 0.2 1 23 636 659 636 659 0.95 11 12 0.084 6.2 7.3 1.3 1 21 665 684 665 687 0.75 12 12 1.3e-07 9.8e-06 25.6 3.0 1 23 693 715 693 715 0.98
Sequence Information
- Coding Sequence
- ATGGACGTGGCGGGCACCTATTCTATACACACCTTGTGCAGGATTTGCCTGAATCACCTGCAGAACGACGCCGCCTACGACCTGTATTTAGTTCCGGGACTCTCGAAAAAACTTTGCTTGTGTACGTCCCTGTCCGTAGAGCCGCAGGACGGGTTCCCGAAGAACATCTGCACCCAGTGCTATACTCGGCTTAACGACCTGCACGACTTCCAGAAGCTATGCGTGGACTCGGTGCAGAAGTTCCAAGACATGGTGGCCAGCAACGCCTTTGTGTGCCAGAGCAACTTCGATGTGCTGGACCCCAGCATCGCCGGGCAGGACATGCACGGCGAGGAGGAAGACCACATCAACTACGACCCCTTGCTGAACCACAAAATGGAACTGATCGAGAACGAGGAGGAGGTCTTTAAGATGCTGGAGCACGTGGACAAGGAGGCCGAGGAGGTGCAGAAGCAAGAGGAGGAGGATGAGAAACCGAGCGGTTCCCTGAAGATGTTCGACGACGACTCCTCCGACGAAAGTGGTAACGACAACGATCGCGACCTGGACTTCGAACCCAACAGCAGTGACGACGACATTCCGCTGGCCCAGCGCATCCGGGAAACGGGGCCGGGTTCGACGTTGTCAGCTCCCAAGGCAGCCCAAGGAAAGCCCCGGGGACGACCCAGAGGCAGGCCTAAGAAGAAACCTGTGGAGGAAGAGGAATTGGATGAACTAAGCGACTCCTCCGAATCGGACGACTCTGACGACGATGGTGACGGTACATCGCGGGATAAGCCGAAGCGGAAGAGGATTCCCCCCGATGAGCGTCACCTGCACCGCATCATTGACTGCCACATTTGCCACCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAATGATCTACTGCCCTTCCAGTGCAAGGTGGAGACCTGCAAGAAAGGATTCACAACTGCCAATGGGCTGCGCATTCACATCGACCACGCCCACACGGAATTGTCTGAAGTCCATCCCTGCCCCGCCGAGGGCTGTGGGAAGACTTTCCCGCGCGTCCGCTTGCTCACGTTCCACATGAAGAAGGTGCACGGCATAACCAAGGCGGCAGCTCCACTGCGTGACTTCCCATGCCCCGAGTGCGACACGGTCTTCCGTTGTCCCACTGCCCTCAAGAAGCACATGTACAAGCACACGGGAGAGGAGCTGCCCTACCCCTGCAACATCTGCGGCAAACGGTTCGTGATCAACAGTGCCCTGAGGGATCATCTTATGCGGCACGCTGGCATCAAGAACCATGTGTGTCCTTACTGCGGGGTGGGCAAGACCACCAGGCAGGAGTGGAACGCCCACATCCTCACGCACACCAAGGAGAAGAAGTTTAAATGCCGACAGTGCGATCACGCGTCCCACAACAAGCAAGCCCTCTCCAATCACGTGAAGGTGGTGCACGAGAAACGGAAGGACTTCGCCTGCCAATATTGCGGAAAGACATTCGGAAAATCTCACGCCTGCAAGGTGCACGAGAGGAGCCACACTGGAGAGAAGTGCTGCGAGTGCAGGATATGCGGCAAGATCTTCCTTTGCGACAAGAGCCTAACGAAGCATCTTAAGACTCACGAGAAGCGGGATCTTCCGCCGTCGGAGCCGCACCGTCAGCAGCTCAACATTCCCATTCCAGGCCAGATGCCGGCGGATCCTACGGGTCTGGCTCAACTGCAGCCGAGTTCTGGGGAAGACATGATGAAGGCGTGTGGCGGCGGGACCGCTGAAGCGCCTACCAAGCCGAAGAACTCGCGTCGTGTCCAGAGAGTAGACATTTCCCAGCTGGCGGGCACCGCTGTGAATCCCATACCATCCGTATCTGTCCCCTCGTGGTCGCCCCAAGTGAACTTCACCAAAAAAGAGGGCCAGCACATCTGCCCGGGCTGCGGACGCGGCTTCAACAACATAGGAAACATGAAGCTCCACTACAAAATTATCCATGAGAAGGTCAAGGACTTTGCCTGCCGTTTCTGCCCCAAGCGGTTCTCCAAGGCGCAGATCCTACGCCACCATGAGTGGATCCACACCGGAGAGAAGCCGTTCGAGTGCAAGATCTGTGGCAAGCACTTCCGCCAGGAGACGGCGCTCAAGAAACACATCAAGACCCACGAGAAGCCGAACAGGCGGCATGTGCCCGAGCGCAGTGCGCCCACGCAAATCACTTTCAGAAAGCTGGAGCCTGATGCGGAGCCGAGGAACTACGACCAGTACCAGGACCCAGCAGCAGAACGAGCGGCGGCCACCGCGGAGCTGCTGGCACACCAACTGGAGGAGAACGAGGCCAGGCGCAAGGCGGACATCGAACGGCAGAAAATCGCGGCAGCCGCCTGTGAACAGCTAACCAAGCTGCAGCAGCAGCAGGACATCATGAAGGCCACCACCTCCTACGATGGCTACTATGCGCAAAAAGCCCAGGCGGAGGGCACCAGTGTGGACGCTCTGAAGATCGACCATGTCTAG
- Protein Sequence
- MDVAGTYSIHTLCRICLNHLQNDAAYDLYLVPGLSKKLCLCTSLSVEPQDGFPKNICTQCYTRLNDLHDFQKLCVDSVQKFQDMVASNAFVCQSNFDVLDPSIAGQDMHGEEEDHINYDPLLNHKMELIENEEEVFKMLEHVDKEAEEVQKQEEEDEKPSGSLKMFDDDSSDESGNDNDRDLDFEPNSSDDDIPLAQRIRETGPGSTLSAPKAAQGKPRGRPRGRPKKKPVEEEELDELSDSSESDDSDDDGDGTSRDKPKRKRIPPDERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHPCPAEGCGKTFPRVRLLTFHMKKVHGITKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECRICGKIFLCDKSLTKHLKTHEKRDLPPSEPHRQQLNIPIPGQMPADPTGLAQLQPSSGEDMMKACGGGTAEAPTKPKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNYDQYQDPAAERAAATAELLAHQLEENEARRKADIERQKIAAAACEQLTKLQQQQDIMKATTSYDGYYAQKAQAEGTSVDALKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00486750;
- 90% Identity
- iTF_00580134;
- 80% Identity
- iTF_00488181;