Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010019984.1:2787-5017[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0092 0.92 10.4 3.7 3 23 154 174 152 174 0.97

2 12 0.00039 0.039 14.7 0.7 1 23 180 205 180 205 0.94

3 12 0.0013 0.13 13.0 1.1 1 23 212 237 212 237 0.96

4 12 5.1e-05 0.0051 17.5 1.3 1 23 249 271 249 271 0.98

5 12 1.4e-06 0.00014 22.4 0.1 1 23 278 300 278 300 0.98

6 12 0.0091 0.91 10.4 0.2 1 23 306 328 306 328 0.97

7 12 0.048 4.8 8.1 3.0 1 23 334 357 334 357 0.97

8 12 0.0077 0.76 10.6 4.4 1 23 363 385 363 385 0.96

9 12 0.076 7.6 7.5 5.3 2 23 392 413 391 413 0.96

10 12 8.5e-05 0.0085 16.8 0.2 1 23 529 552 529 552 0.95

11 12 0.073 7.3 7.6 1.3 1 21 558 577 558 580 0.75

12 12 1.2e-07 1.2e-05 25.8 3.0 1 23 586 608 586 608 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0092	0.92	10.4	3.7	3	23	154	174	152	174	0.97
2	12	0.00039	0.039	14.7	0.7	1	23	180	205	180	205	0.94
3	12	0.0013	0.13	13.0	1.1	1	23	212	237	212	237	0.96
4	12	5.1e-05	0.0051	17.5	1.3	1	23	249	271	249	271	0.98
5	12	1.4e-06	0.00014	22.4	0.1	1	23	278	300	278	300	0.98
6	12	0.0091	0.91	10.4	0.2	1	23	306	328	306	328	0.97
7	12	0.048	4.8	8.1	3.0	1	23	334	357	334	357	0.97
8	12	0.0077	0.76	10.6	4.4	1	23	363	385	363	385	0.96
9	12	0.076	7.6	7.5	5.3	2	23	392	413	391	413	0.96
10	12	8.5e-05	0.0085	16.8	0.2	1	23	529	552	529	552	0.95
11	12	0.073	7.3	7.6	1.3	1	21	558	577	558	580	0.75
12	12	1.2e-07	1.2e-05	25.8	3.0	1	23	586	608	586	608	0.98

Sequence Information

Coding Sequence: AACGAGGAGGATGTGTTCAAGATGCTGGAGCACGTGGACAAGGAGGCCGAGGAGGTGGAGAATGGCACCAAGCAGGAGGAGGAGGACGATAAAGCCGGCGTCAGCCACATTAAGATTTTCAACGACGACTCCTCCATCGAGAGTGGCAACGACAACGACCGCGATCTGGACTTTGAGCCGAACAGCAGCGACGACGACATTCCTCTGGCCCAGCGCCTGCGAGGACCTGGGCCAGGGTCATCCCAGCACGGTCGCCAGGCCACATACACCAAGGCGAAGGGCAAGCCGCGGGGCAGGCCCAAGAAGGTAAAGCCGCCGCCGCCGGATGAGGACGAGTTCACCAGCGACTCCGACGACTCGGATGACTCGGAGGAGGACAACCCCGACGGAACGCCCAGGGAAAAGCCGAAGAGGAAACGCATTCCCGCCGACGAGCGACATCTGCACCGCATCATCGACTGCCACATTTGCCACCAGAAGTTCAAGAAGGCGATCCGCTACGAGGAGCACATGAAGTACCACAACGACCTGCTGCCCTTCCAGTGCAAGGTGGAGACCTGCAAGAAAGGCTTCACCACGGCCAACGGCCTGCGCATCCACATCGACCACGCCCACACCGAACTGTCGGAGGTGCACACTTGCACCGCCGAAGGCTGCGGCAAGACCTTCCCGCGCGTCCGCCTGCTCACCTTCCACATGAAGAAGGTGCACGGCTTGACCAAGGCGGCGGCACCGCTGCGGGACTTCCCCTGTCCGGAATGCGACACGGTTTTCCGCTGCCCCACGGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGGAGCTGCCCTACCCGTGCAACATCTGCGGCAAGCGGTTCGTGATCAACAGCGCTCTGCGGGATCACCTGATGCGGCACGCGGGCATCAAGAACCACGTCTGCCCCTACTGCGGCGTGGGCAAGACGACGCGCCAGGAGTGGAACGCCCACATCCTCACGCACACCAAGGAGAAGAAGTTCAAGTGCCGGCAGTGCGACCACGCCTCCCACAACAAGCAGGCGCTGTCCAACCACGTCAAGGTGGTGCACGAGAAGCGCAAGGACTTCGCCTGCCAGTACTGCGGCAAGACCTTCGGCAAGTCGCACGCCTGCAAGGTGCACGAGCGGAGCCACACCGGGGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATATTCCTCTGCGAGAAGAGCCTCACGAAGCATCTGAAGACGCACGAGAAGCGCGACCTGCCGCCCTCGGAGCCCCTCCGCCAGCAACTGAACATTCCCATGCCCGGCCAGATGGCGGGCCAGATGCCGGGCCAGATGCCGATGCAGATGCAGGGTCAGGGCGATGGCCTGCTGCAGCAGATGCAGCCTCCCAATCAGATGCCCAGTGACGACATGCTCAAGGCGTGCGGCGGCGGGTCCGCTGCAGGGCCTGCGGCGAAGCCGAAGAACTCGCGCCGCGTACAGCGCGTGGACATTGCTCAGCTGGCCGGCACCGCCGTCAACCCCATACCCTCTGTCTCGGTGCCGTCGTGGTCGCCGCAGGTGAACTTCACCAAGAAGGAGGGCCAGCACATCTGCCCGGGCTGCGGCCGTGGCTTCAACAATATTGGCAACATGAAGCTCCACTACAAGATCATCCACGAGAAGGTCAAGGACTTCGCCTGCCGCTTCTGCCCCAAGCGGTTCTCCAAGGCGCAGATCCTGCGCCACCACGAATGGATCCACACCGGCGAGAAGCCCTTCGAGTGCAAGATCTGCGGCAAGCACTTCCGCCAGGAGACGGCCCTCAAGAAGCACATCAAGACGCACGAGAAACCCAACCGCCGGCACGTGCCCGAGCGCAGTGCGCCCACCCAGATCACGTTCCGGAAGATAGATCCGGACGAGCCGCGGAACTTCGACCAGTACCAGGATCCGGCGGTGGAGCGGGCGGCGGCCACCGCCGAGCTCCTGGCCCACCAGCTGGAGGAGAACGAGGCCAGGCGGAAGGCGGACATCGAGCGCCAGAAGATAGCGGCGGCTGCCTGCGAGCAGCTGACGAAGCTGCAGCAGCAGCAGGACATCATCAAGGCGACCACCTCGTACGACGGCTACTACGCGCAGAAGGCCCAGGCCGAGGGCACCAGCGTCGATGCCCTGAAGATCGACCATGTCTAG
Protein Sequence: NEEDVFKMLEHVDKEAEEVENGTKQEEEDDKAGVSHIKIFNDDSSIESGNDNDRDLDFEPNSSDDDIPLAQRLRGPGPGSSQHGRQATYTKAKGKPRGRPKKVKPPPPDEDEFTSDSDDSDDSEEDNPDGTPREKPKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHTCTAEGCGKTFPRVRLLTFHMKKVHGLTKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPSEPLRQQLNIPMPGQMAGQMPGQMPMQMQGQGDGLLQQMQPPNQMPSDDMLKACGGGSAAGPAAKPKNSRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKIDPDEPRNFDQYQDPAVERAAATAELLAHQLEENEARRKADIERQKIAAAACEQLTKLQQQQDIIKATTSYDGYYAQKAQAEGTSVDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486750;
90% Identity: iTF_00483135;
80% Identity: -