Dmay005572.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mayri
Gene Symbol
-
Assembly
GCA_008042485.1
Location
VNJN01001072.1:41982-44608[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.012 0.81 10.1 3.7 3 23 286 306 284 306 0.97
2 12 0.00049 0.034 14.4 0.7 1 23 312 337 312 337 0.94
3 12 0.0017 0.12 12.8 1.1 1 23 344 369 344 369 0.96
4 12 6.4e-05 0.0044 17.2 1.3 1 23 381 403 381 403 0.98
5 12 1.8e-06 0.00013 22.1 0.1 1 23 410 432 410 432 0.98
6 12 0.011 0.79 10.1 0.2 1 23 438 460 438 460 0.97
7 12 0.06 4.2 7.9 3.0 1 23 466 489 466 489 0.97
8 12 0.0096 0.67 10.4 4.4 1 23 495 517 495 517 0.96
9 12 0.095 6.7 7.2 5.3 2 23 524 545 523 545 0.96
10 12 0.00011 0.0074 16.5 0.2 1 23 661 684 661 684 0.95
11 12 0.092 6.4 7.3 1.3 1 21 690 709 690 712 0.75
12 12 1.5e-07 1e-05 25.5 3.0 1 23 718 740 718 740 0.98

Sequence Information

Coding Sequence
ATGGACGTGGCGCGCACCTACTCAATTCACAGCCTTTGCAGGATTTGCCTAAACCACCTGCAGAACGACGCCGACTTGTATGACCTGTATCTTGTGCCAGGACTGGCCAAGAAACTTTGCTTCTGCACGTCGCTGTCCGTGGAGCAGAACGATGGCTTCCCCAAGAACTTGTGCACCCAATGCTACTCGAAGCTCACCGAGCTGCACGATTTCCAGCGACTGTGCGTGGATTCGGTGCAGAAGTTCCAGGACTTGGTCGCCAGCAACGCCTTTGCCTGCCAGAGCAACTTCGATGTGCTGGACCCGAGTGCGTCCGTGCATGACATCCccggcgaggaggaggagaacaTCAACTATGACCCGCTGCTGAACCACAAGATGGAGCTAATCGAGAACGAGGAGGATGTGTTCAAGATGCTGGAGCACGTGGACAAAGAGGCCGAAGAAGTGGAGAATGGCACCAAgcaagaggaggaggacgatAAAGCTGGCGTTAGCCACATCAAGATTTTCAACGACGACTCCTCCATCGAGAGTGGCAACGACAACGACCGCGACCTGGACTTTGAGCCGAATAGCAGCGACGACGACATTCCGCTGGCCCAGCGCCTGCGAGGACCTGGTCCAGGATCATCTCAACCAGCACGCCAGGCCACATATACCAAGGCGAAGGGAAAGCCGCGTGGCAGGCCCAAAAAGATaaagccgccgccgcccgacGAGGACGACTTCTCCAGCTTCTCCGACGACTCTGATGACTCGGAGGAGGACAACAACCCCGACGGAACGCCCAGGGAAAAGCCGAAAAGAAAGCGCATTCCCGCTGACGAGCGCCATCTGCACCGCATCATCGACTGCCACATCTGCCACCAGAAATTCAAGAAGGCGATCCGCTACGAGGAGCATATGAAATACCACAACGACCTGCTGCCCTTCCAGTGCAAAGTTGAGACCTGCAAGAAAGGCTTTACTACGGCCAACGGCCTGCGCATCCACATCGATCACGCCCACACCGAACTGTCGGAGGTACACACTTGCACCGCCGAGGGCTGCGGCAAGACCTTCCCGCGCGTCCGCCTGCTCACCTTCCACATGAAGAAGGTCCACGGCCTAACCAAGGCGGCAGCACCGCTGCGCGACTTCCCCTGTCCGGAATGCGACACAGTCTTCCGCTGCCCCACGGCCCTCAAGAAGCACATGTACAAGCACACAGGCGAGGAGCTGCCTTATCCGTGCAACATTTGCGGCAAGCGGTTCGTGATTAATAGCGCTCTGAGGGATCACCTGATGCGGCATGCGGGCATCAAGAACCACGTCTGCCCCTACTGCGGCGTGGGCAAGACGACGCGCCAGGAGTGGAACGCCCACATCCTCACGCACACCAAGGAAAAGAAGTTCAAATGCCGGCAGTGTGACCACGCCTCCCACAACAAACAGGCCCTGTCCAACCACGTCAAGGTGGTGCACGAGAAGCGCAAGGACTTCGCCTGCCAGTACTGTGGCAAGACCTTCGGCAAGTCGCACGCCTGCAAGGTGCACGAGCGGAGCCACACCGGAGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATCTTCCTTTGTGAGAAGAGCCTAACGAAGCATCTGAAGACGCACGAGAAGCGCGACCTGCCGCCGGCGGAACCACTTCGCCAACAACTGAACATTCCTATGCCTGGCCAGATGGCAGGCCAAATGCCCGGCCAGATGCCGATGCAGATGCAGGGCCAGGGCGATGGCTTGATGCAGCAGATGCAGCCTCCCAATCAGATGTCCAGTGATGACATGCTCAAGGCATGCGGCGGCGGGTCCGCTGCAGTGCCTCCTGCGAAGCCGAAGAACTCACGTCGCGTACAGCGGGTGGATATTGCTCAGCTGGCGGGAACCGCCGTCAACCCCATACCCTCTGTGTCGGTGCCGTCATGGTCGCCCCAGGTCAACTTCACCAAGAAGGAAGGCCAGCACATCTGCCCGGGCTGCGGGCGTGGCTTCAATAACATTGGCAACATGAAGCTCCACTATAAGATCATCCACGAGAAGGTCAAGGACTTTGCCTGCAGGTTCTGCCCCAAGCGGTTTTCGAAGGCGCAGATCCTGCGCCACCACGAATGGATCCACACCGGCGAGAAGCCCTTCGAGTGCAAGATATGTGGTAAGCACTTCCGACAGGAGACGGCCCTCAAGAAGCACATTAAGACGCATGAGAAGCCCAACCGCCGGCACGTGCCCGAGCGCAGTGCGCCCACCCAGATCACTTTCCGTAAGCTAGAGCCGGACGCCGAGCCGCGGAACTTTGATCAGTACCAGGATCCGGCGGTGGAGCGGGCGGCGGCCACCGCCGAGCTGCTGGCCCACCAGCTTGAGGAGAACGAGGCCAGACGGAAGGCGGACATCGAGCGTCAGAAGATAGCGGCCGCCGCCTGCGAGCAGCTGACGaagctgcagcaacagcaggacaTCATCAAGGCGACCACCTCGTACGACGGCTACTACGCGCAGAAAGCCCAGGCCGAGGGCACCAGCGTCGATGCCCTGAAGATCGACCATGTCTAG
Protein Sequence
MDVARTYSIHSLCRICLNHLQNDADLYDLYLVPGLAKKLCFCTSLSVEQNDGFPKNLCTQCYSKLTELHDFQRLCVDSVQKFQDLVASNAFACQSNFDVLDPSASVHDIPGEEEENINYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVENGTKQEEEDDKAGVSHIKIFNDDSSIESGNDNDRDLDFEPNSSDDDIPLAQRLRGPGPGSSQPARQATYTKAKGKPRGRPKKIKPPPPDEDDFSSFSDDSDDSEEDNNPDGTPREKPKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHTCTAEGCGKTFPRVRLLTFHMKKVHGLTKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPAEPLRQQLNIPMPGQMAGQMPGQMPMQMQGQGDGLMQQMQPPNQMSSDDMLKACGGGSAAVPPAKPKNSRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNFDQYQDPAVERAAATAELLAHQLEENEARRKADIERQKIAAAACEQLTKLQQQQDIIKATTSYDGYYAQKAQAEGTSVDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00486750;
90% Identity
iTF_00483135;
80% Identity
-