Basic Information

Gene Symbol
ZNF236
Assembly
GCA_004195275.1
Location
SGAY01000579.1:11525-19161[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 6.7e-05 0.0086 17.2 1.1 2 23 27 48 27 48 0.98
2 23 2.6e-06 0.00033 21.7 1.1 1 23 69 91 69 91 0.99
3 23 1.9e-05 0.0024 19.0 0.3 1 19 97 115 97 116 0.97
4 23 3.3e-05 0.0042 18.2 1.1 1 23 125 148 125 148 0.96
5 23 0.0027 0.35 12.1 1.5 1 23 157 180 157 180 0.97
6 23 4e-07 5.1e-05 24.2 0.4 1 23 304 326 304 326 0.98
7 23 0.00057 0.073 14.3 0.8 1 23 332 354 332 354 0.99
8 23 0.1 13 7.2 4.7 1 23 360 382 360 382 0.97
9 23 0.032 4.1 8.8 4.0 1 21 386 406 386 408 0.94
10 23 0.0041 0.52 11.6 6.2 1 23 463 485 463 485 0.97
11 23 3.3e-05 0.0042 18.2 4.9 1 23 491 513 491 513 0.99
12 23 9.7e-06 0.0012 19.9 2.1 1 23 519 541 519 541 0.98
13 23 0.001 0.13 13.5 8.2 1 23 547 569 547 569 0.98
14 23 0.19 25 6.3 2.1 2 23 928 949 927 949 0.96
15 23 0.00065 0.083 14.1 3.6 1 23 955 978 955 978 0.98
16 23 0.0019 0.24 12.6 4.5 2 23 983 1004 982 1004 0.97
17 23 2.9e-08 3.8e-06 27.8 1.4 2 23 1076 1097 1075 1097 0.98
18 23 9.2e-05 0.012 16.8 5.0 1 23 1103 1125 1103 1125 0.99
19 23 0.00012 0.015 16.5 4.1 1 23 1131 1153 1131 1153 0.97
20 23 4.3e-05 0.0055 17.8 3.5 1 23 1159 1181 1159 1181 0.99
21 23 1.5e-06 0.00019 22.4 0.8 2 23 1430 1451 1429 1451 0.97
22 23 1.7e-05 0.0022 19.1 4.6 1 23 1457 1479 1457 1479 0.98
23 23 6.2e-05 0.008 17.3 7.6 1 23 1485 1508 1485 1508 0.97

Sequence Information

Coding Sequence
ATGGTATACTGGgCCCAACTAGACGCGCATTTGAAGCTTCACGGAGAAAAGTGGACGATTGAGGATGCTGGTGTACGAAAGtgtaaattatgcaataaacaATTCACGCAACCTGCGCTCTACCGAATGCACATTCGCGAACATTATAGGCTACAGACGAAGATAGTAAAGCAAACTAAGAGGGGAACGAAACATAAAACAATGTACAAATGTACCATATGTTTGAAGAATTTCCAAAAGCCGAGCCAACTGATGCGGCATATCAGAGTGCACACCGGAGAGAAACCGTTTAAGTGTACCGTTTGCAATAGAGCATTTACACAAAAAAGTTCGCTACAAATTCATGCGTGGCAGCACAATGGTATCCGGCCACACAGCTGCAATCTCTGCAGCGCCAAATTTAGTCAGAAAGgAAATCTAAAGGCGCATATACTCAGAGTACATAATGTACCAGAAGGTGAACCGACATACGCCTGTTCTTATTGCTCTTGCATTTTCAAGAAGCTAGGCAGCTTAAACGGTCACATCAAGCGAGTGCATTCTAATCCGGAGGAGGAATCCGCTGATAAATCCTCGACTGCTAATTCTAATATCTCTTCGGAAGCTGACATGCGCGCGACGGTCGATAGCGTTATTTCGCAATTGGCGTCTTTGGAAGCTGTCGTAAATAATACCGCAAGTTCCACGGGATCCGCTGAAATACTAAGTGCAGAACAGAACGATATCTTGCAACAGGCGTTGAAAAATAGTGGTTTACCGAACAAAAACGAAATCCCTTTGAAAGAAATCACAGAGTCGAAAAAGGCGGATTTGCCAACAACATATGTCACATTGTTGGACAAGACTGCTGGCAGTACTTCGAAgaAATATCATGCCATAAAGCAACGTTGCATAGGAAATGTACGGTGGTACGTATGTTCCTTTTGCCCGAAAGAATTCAAAAAGCCGTCGGATTTGATACGTCACTTACGGGTGCATACGCAAGAAAAACCCTTCAAGtgtATGTATTGCGTGCGTTCCTTCGCGCTAAAATCGACAATGATAGCGCACGAACGAACTCACACCGGAATAAAGAAGTACGCTTGCGTTTCCTGCAATAAAACTTTCGCGTGCCATAGTAGTCTTACCTCTCATACTAGATTACATATGAAACCGcacaaatgtaatatatgcgGCAAGTTATTCAACTCGAGCATCATCCTGAAAAATCATATGAAATGTCACGTGCAGGAAAAGCCCAAAACATCGCCGGAAGCAGAGAGCTTAGTGCCTCAAGTAGTACTGCAGGAGCCACTTGTCATCAGCGACGCTGGTAACAAGATCAGTGTTGCCCAAGTGCAATCGAAACAAAAACAATTGTATGAGAATGCCGGTGTGACCAGGCCGCATGAATGTTTGGTCTGTCACGCGGCATTCAGGAAAGTCAGCCATTTGAAACAACATTATCGTAGGCATACGGGCGAACGTCCTTACAAGTGTTCCAAATGCGACAgGAGGTTTACATCAAATAGTGTTCTGAAATCTCACTTGCACACGCATGACGACGCGAGGCCATACAGTTGTTCGGTATGCAATACAAAATTCTCCACACAAAGTAGCATGAAGAGGCATTTAGTAACACATAGCAATAAAAGGCCATTTATGTGTCCATATTGTCATAAGACGTTTAAGACGTATGTCAATTGTCGAAAACACATAAAAAGACACAAACACGAACTGGTGCAACggCAATTAGAAGAACAAAAGACGCAAGAGCAAAAAGAACAACAACCTTTGAGAGAAAACAAAGAAGCTGGCTCAGTAGCCTTATCGACAAGCATCTCTCTCGCCGAAGATATAGAAGTGTCGTTCCAACCGCAAATGGCGCCCGATTTCACGCAAGCCTTTTCTGATCAGTTTCAAAATATCAGCGTAGAGAAAGATAAGTCTTTCTTATTGACAAACAGTGCGACAACGTCAGCAACAAACCaaaatttatctGTTGACACAACTAATTTAGAAACTTCGCAAACTTTACATGCTGATGAAACTGGCACTATCACGTTGTCACATTACTCAGGAGATCAAACCTTTACAGCggaaagCATACAAGAGATCGAGGAGACATTGAATCAACAACTGTTTAATATTGGTATGAATCTCGGATTGGCAAACAATTTACCGAAGCAGATGGACGAGACGAATACGAATTCTCTTGACAATTCTAGGGAACAGCCAGtgcttaatataatttatgagcaTAACAAAAATCTAGATTCATCTGGCAATACTATATTCACATCGCAATTCGATTCATTTGACATGAGCCAAATTACGTTACAGACGGACAGTGAGATGGATATCAGTTTGAATCCAACCAACACGACGAGCATATCTAGTATTTTGCCCAGATCCGTGGAAGGAGACGATAGACAACAAGAAGAACAACGTGCTATTCCAGTAACTACAGTTGATAGTATGGATGCTTCTGCAATTACGAAGAATGCTCATCTAATGGTAATCAATTCTAAGGATAATTGTTCAGAATTGATGAGCCTTTCGCAAGTATGTCCATCGAAGTATTCGAAAGTCATCGCGAAAGCAGACACTACAAACGGATTAATTGAAATGCAAGACACGACTAAACATGAAAAAGTGTCACAGAAaagtaatgttatattatgcgagagcgagagaaactCTTTATTCATGAAGAACTTCCAAAGTACGATACAGCCAGATACACTCGTTTCTTCAGGAACGAATAATTCTGCCAAAATATCGgagtacaataatttattggaGTGTCACATATGCCATCGTAATGGTTTCACAGCAGAAAGATTGAAGGAACATTTGGAATCTCATTGCGGTGCCAAAATTTATGAGTGTTCGAAGTGTTCCCAGCGATTCCATACAAATGGTGGTCTCAACAGGCACACAAAGAGGCTGCACACAGAGTTATTGAAATGTACGACTTGTAAGAAGGTGCTGGACAGTAAATCGCAATTGAAACATCACAGCAAAATGCATAGTGGGGTTTTGAAAGTTGTACGCCTGGAATCGAATGAAAAGGATGTAATCTCCTCCAGTTCCCGTCTTCCGTCTATAACGGTGCTAGATGTCCAAATGAACACAGACTCGTCGGTATCCGAGAAAGTATTGATGGACGCAGTTGCTGAGAGGAAAAGCATGGACCGCGTAGATGAAAACACGGAGAGGAAAGAGACAAAAGAATATACGAACAAATGCAAGTATTGTCCGAAAACTTTCCGAAAGCCAAGCGATCTTATTAGGCACATTCGCACGCACACGGGCGAACGGCCATACAAGTGCGATCACTGCAACAAGAGCTTCGCGGTTAAATGCACTCTGGACTCGCATATGAAAGTTCATACGGGCAAGAAGACATTCTGCTGCCACGTATGCAACAGCATGTTCGCTACGAAAGGCAGTTTAAAGGTCCACATGCGACTGCACACGGGTTCGAAGCCATTCAAGTGTCCCATGTGCGATCTGCGATTTCGCACTTCGGGTCATAAAAAGGTACACATGCAGAAACATGCAAGAGAACATAAGAGCGGCGCGAAGCGCAAGCCTAAACACCAAAAGGTCGCGGCAGTAGCGGAAGTAGCGGCTAGCCTCGAAAAGATTGGCAACAGTTCTCTGGACCAAACATCGaggacgacgatgacgacgacgccAATCGTGATTAATGGCAGCGAGGTTGCACCATCGCAGGATCTTGATTATTCTTCGTTAGAGCATACTGAAATGAATCTTAATAGCGCGGTTCATTTGTCGAATCAAATCACGTTTAATCATACCGACGCGACGACAGCGACGATTCTTAACAACAATTCCATGCTGTCTTTGAATGACAGCAACGAGCTGGTGGCGAATCTGCAATTCCTGCTAGCGAACGGTCTCGTTACTATTCAAACAGACGATACCATGCTGACGACGCAGTCAGCAGGAAACAGTGCCCCTGAAATGCCAACTAACGTGATCGAATTAGTTGGTACGAATCCTTTCCAGGAAGCTTGCAATCTCAGTAACGCTAATCATCAAATAGTGATAACCAACCAGGTGTCAACTGAAACGACGACCACAAGTACGAGTGACGCGGCGATTATTCAAATGAACAATTGTTTGCCACCTGTTTCCATAGTACAGATGCAGAATCAAGGTATGAACATTGGTGATGACGCATCCAAAGCAAAGATAAGCAATCAATTGACAACAACATGTGTCAATCAAGCGGTGGCAATGGAGACAGCTAAAACCTCGACGCAGTCATCGCGAAAGGAGTGCGACATATGTGGCAAGACATTTACAAAGCCGTATCAGATGGAGCGGCACAAGCGCATCCATACAGGCGAACGGCCATACAAGTGCGAGCAATGCGACAAGTCATTCGCGCAAAAGTTTACGCTGCAGCTACATCAGAAGCATCATACCGGCGACCGGCCATATCCCTGTCCACACTGCAAGCATTCGTTCACGCAGAAATGCAATTTGCAAACTCATCTGAAGCGTGTTCATCAGCTGGTTATGCTTGATGTCAAAAAACTGAAAAGCAGTCAACAGATGTTAGGCACACTTCTACAGGAAAATCAAGGAGCAGACACTAAATTGATGAATCTGGATGATATACTAGTGGTCGATTTTCTTAAGTGA
Protein Sequence
MVYWAQLDAHLKLHGEKWTIEDAGVRKCKLCNKQFTQPALYRMHIREHYRLQTKIVKQTKRGTKHKTMYKCTICLKNFQKPSQLMRHIRVHTGEKPFKCTVCNRAFTQKSSLQIHAWQHNGIRPHSCNLCSAKFSQKGNLKAHILRVHNVPEGEPTYACSYCSCIFKKLGSLNGHIKRVHSNPEEESADKSSTANSNISSEADMRATVDSVISQLASLEAVVNNTASSTGSAEILSAEQNDILQQALKNSGLPNKNEIPLKEITESKKADLPTTYVTLLDKTAGSTSKKYHAIKQRCIGNVRWYVCSFCPKEFKKPSDLIRHLRVHTQEKPFKCMYCVRSFALKSTMIAHERTHTGIKKYACVSCNKTFACHSSLTSHTRLHMKPHKCNICGKLFNSSIILKNHMKCHVQEKPKTSPEAESLVPQVVLQEPLVISDAGNKISVAQVQSKQKQLYENAGVTRPHECLVCHAAFRKVSHLKQHYRRHTGERPYKCSKCDRRFTSNSVLKSHLHTHDDARPYSCSVCNTKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHIKRHKHELVQRQLEEQKTQEQKEQQPLRENKEAGSVALSTSISLAEDIEVSFQPQMAPDFTQAFSDQFQNISVEKDKSFLLTNSATTSATNQNLSVDTTNLETSQTLHADETGTITLSHYSGDQTFTAESIQEIEETLNQQLFNIGMNLGLANNLPKQMDETNTNSLDNSREQPVLNIIYEHNKNLDSSGNTIFTSQFDSFDMSQITLQTDSEMDISLNPTNTTSISSILPRSVEGDDRQQEEQRAIPVTTVDSMDASAITKNAHLMVINSKDNCSELMSLSQVCPSKYSKVIAKADTTNGLIEMQDTTKHEKVSQKSNVILCESERNSLFMKNFQSTIQPDTLVSSGTNNSAKISEYNNLLECHICHRNGFTAERLKEHLESHCGAKIYECSKCSQRFHTNGGLNRHTKRLHTELLKCTTCKKVLDSKSQLKHHSKMHSGVLKVVRLESNEKDVISSSSRLPSITVLDVQMNTDSSVSEKVLMDAVAERKSMDRVDENTERKETKEYTNKCKYCPKTFRKPSDLIRHIRTHTGERPYKCDHCNKSFAVKCTLDSHMKVHTGKKTFCCHVCNSMFATKGSLKVHMRLHTGSKPFKCPMCDLRFRTSGHKKVHMQKHAREHKSGAKRKPKHQKVAAVAEVAASLEKIGNSSLDQTSRTTMTTTPIVINGSEVAPSQDLDYSSLEHTEMNLNSAVHLSNQITFNHTDATTATILNNNSMLSLNDSNELVANLQFLLANGLVTIQTDDTMLTTQSAGNSAPEMPTNVIELVGTNPFQEACNLSNANHQIVITNQVSTETTTTSTSDAAIIQMNNCLPPVSIVQMQNQGMNIGDDASKAKISNQLTTTCVNQAVAMETAKTSTQSSRKECDICGKTFTKPYQMERHKRIHTGERPYKCEQCDKSFAQKFTLQLHQKHHTGDRPYPCPHCKHSFTQKCNLQTHLKRVHQLVMLDVKKLKSSQQMLGTLLQENQGADTKLMNLDDILVVDFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2