Cvom008617.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Calliphora vomitoria
Gene Symbol
zfh1
Assembly
GCA_942486075.2
Location
CALNXM020000192.1:1073066-1082716[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00018 0.0088 16.7 0.7 1 23 198 220 198 220 0.95
2 15 0.059 2.9 8.7 1.2 3 23 228 248 226 248 0.95
3 15 0.00032 0.016 15.9 0.5 1 23 426 448 426 448 0.98
4 15 0.0022 0.11 13.3 0.4 1 23 454 476 454 476 0.98
5 15 0.00011 0.0056 17.3 3.7 1 23 508 530 508 530 0.97
6 15 0.015 0.75 10.6 0.3 1 23 551 573 551 573 0.94
7 15 0.013 0.65 10.8 0.8 1 23 579 602 579 602 0.97
8 15 0.48 24 5.9 0.4 5 19 613 627 610 628 0.91
9 15 0.00029 0.014 16.0 5.6 1 23 637 659 637 659 0.97
10 15 0.064 3.2 8.6 1.7 2 23 665 686 664 686 0.97
11 15 9.1e-05 0.0044 17.6 0.2 1 23 695 717 695 717 0.98
12 15 0.0086 0.42 11.4 0.2 3 23 725 745 723 745 0.97
13 15 0.0001 0.005 17.4 0.5 1 23 751 773 751 774 0.95
14 15 0.011 0.55 11.0 0.0 1 23 784 806 784 806 0.97
15 15 0.025 1.2 9.9 0.0 1 20 1383 1402 1383 1405 0.93

Sequence Information

Coding Sequence
ATGGATAATCATGGCTATGGTGGCATACAGTGGATACAACACCACTCGGGTAATCACTCCTCCCATGCTGGAGATATGAAAACTGCTGGTCAGTTGATGATAGATCCTCAGCCGCCGCGTGAAGAGGATCTTATGGCCAGTGCCAATTCATCGTCGGACTATATGGCCACTGAGGATGAAACCGATTCGGCAACTATAGCCCAAATAGCGGCGGAAAATCTAATTTTTATGGCTCGCGATGGTCAAATGATGACGGAAATAATAACAAATACTACGACCGATGCAAATGGAACTGTGGTTGTGACTGCCAGCGACGGCGAACAGATTGACTGCGATGCCATTATGGAACAGGCTGCCTTAATACAACAGCACGAAGATGCTGGTGGTGGAGTCTATAGTGTGGAGCATTTTAGCGAGAATACACCGCAAATGGTGACGGAAGAGGTCATCACCGATGATTGGGTGCAACATCAAGGGGAAGAAAGAGTTGAAATACCTGCCGAACAAATTATTGGCTCAAGTTCCCAGGTGCTGTTGGACATTGAAGTGCCCCTGCCAACCGTACAAGATGAATACACTGCCCTGCGACCATACCCCTGTGACTTTTGTAGTCGACGATTTCGTAAAAAAGCCAGTCTAATGAATCATATGGTGGCTCATCAAACGGATCGGCCACATTTGTGTAAATTATGTGGAGCCAGATTTCTAAGGAGACAAGATCTCATAAATCATCTAAAAGGGCATGCAGAAGAGCCCACAGAACCACAAATGGATGATAGTGATTTCATACATTTTGTTACCGACACCACTTCCTCCTCACAACGTACTTCCAACGATCATTACTATGAACAGGATTGGAGTGTACCCGAAGATTCGGTAACCATACCAACAAAATCTAGTCGTAAACATCAACAACAACCGCAACAACTGCAACATATTACCTCCATTTCTAATCAACAAATCATGATGGAAAATACTATAACCTCATCATCCCCCCAAGATGTGCTAACAACTACACAAACTACCACAGCACCGCCTAGAGGACGTATAAGTCGTCTCAAGCCTAAAGAGGACACATCCTATGTGGTCGAAGTACCCAATAATTGTTCATCAAGTGAAATGATTATCTCCTCGGCTTACAGCATTGTAGAATGTGATACTTTGTCTGCCAATACGGCAGCCGTTAAACTTTCTCAGGACAATACACCCGCTCTGCATGAAAATGATGAAGAACATAATGTGCTACACTATCCCGTTATAGATGATAGCAAACCATTCGTTTGTCAACAATGTGGTTTGGCATTTTCCAGGGAAAAAGCCATGCTATCACATACCAAGACACATCGTAATGATTCTCCCTTTGAGTGCCCCCAATGCAATGAATTGTTTTGGGATCAAAATAGTTTACAGGATCATCAAAAAACTCATCAGTTTGAAGAAAGCAATTCGGAATATGACCCCAATGAAGGCGAAGATGAAACACAAACCGAATCGGAGTCCGAACAACAATTATATGGTGAATTTTATTGCAGTGAATGTGGCATGTCGTTTCATCGCCAGGATCTTTTAAAAAGGCATTCTAAAAATCATCCTGCTGGTAATGTGACTATGGGTCAATCTGCACACAATGGCATGGAGAGTAGAGATCAACATTGTTGTAATACTTGTGGAGAAACATTTGCCGAGGCTTTAGATCTATTAGCGCATGCCGAAATACATGCACGTTACCCGCCCTTCAAGTGTGTTTTATGTGGTGAATCTTTTTTCGAGGAAACCACCATCAAAAAACACCTGCAGTCCCAGCATCCCAATGAAATTACCGAGAATTCTTGCATCCTGTGTGGCAAAGAGTGCCGTGATCGTAAAGCCTTAATGAAACATGCCTGGGATCATTCCCGAGAAAAATGCCACTCTTGTTCGAAATGTGGCAAAAATTTCCACAACAAGGCGCGCCTTAAACGCCATATGGCCTCACATCGCGACAAGTCCGTACAATGTGATGTATGTCACGAAGAATTTCCCGATGGTCGCACTCTATCCAATCACCGCCACTCGCACAGTGCCACCTCGGCGGGTAAACTATTCCCCTGCCTGGAATGTGGTAAAACCTTTGGCTCACGGAGTTCCCAACAGATACACGTACGCATTCACACCGGCGAACGGCCCTATGGTTGTCGTTTCTGTTGGAAAGCATTTGCCGATGGTGGTACGCTACGAAAGCATGAACGTATTCACACGGGAGAGAAGCCATATGCTTGCTCCGTGTGTCCTCGTGCCTTTAATCAGCGAGTCGTGTTGCGTGAGCATATACGTTCGCATCATTCGGGTTTGGATGCCAAGAGAGGCACCTATTATTGTACGGTCTGTGGTGCTGAGTTGTATTCGTCGGGAGATTTGATACAACATTTAATACAACACAGTGATATGAATACAGCTATGCAAAGGCAACCAGTGACTGGTCCTCGGAAATATAAACGTAGACGCAAATTGAAACCTCATGAACTGGCACGACTAAAACGTGAAGTCAAACATAATGGTGGCACTGGAAGTGACATTGATTTATCCGACTTTGATATAGACAATGTAGACGATTTGCTGGCAATGACAACCGACAGCAATACGGCAACAGAAACAGTAACAACGGGTCATGAACCGACAGTCTCCCTACCAGGAAAGGCAACGAAGCGAAAGAATGTCTCAGCCACCATAAACACTGAAAGCAATAATACTAATAAAAGTAAAGCAACCATAAACAAAAATAACAAATCACACATTTTAGAAGATCAAGAAGATTTCGATTTAGATGTGGGTATAGATGATGATGAACTTAAAAAACAACGTTACAACTCTACAAGTAGTGATAAAATTTGGCCCGCAAAACAAACCGATGACACCTATAAATCCCTGTTATCGAATTTGGAGACAACTCTTCAAAGTATAGACACTTTAGTGGTGGGACCATCAACAAAATCCTCCCATACCATAGAAAATAACATGCTGGAAACACAGCAGCGTCAGACAAAGCGTAAAATTAAGCAAGAGTCCACCTCGACGGCTCAGAGAACACAACAGGTGCAACTAACAAGAGTAGACAAAGATCCATCTACTACCACAAATGGCAGAGGTCGTAAAAGTAAAACCGGCACCAAACAAACCAAAGGACCACAAATGATACACACAGAAAAATCAACTACAACTACAACTGACAATGGTGGTGGTTCAGCAACAGGCAAAAAGAAATCGAAATCCATTATAACAAGAACACAAACCACAGCTATAGATTTACTGCCTAAAACTTCGGCCATAGTGGATGATTATGACATTATATCGCCCGCCTTGCAACCGCCCAAACAAATTAGCTCTAGTCCTTTGCATATAAAACAGGAACAAGATAATCACAAACACAACTATCACCACCATCCACAGCAGCATCATTTAATGAAAAATCCTCCAAATACAAATCACACCACATCTGCCCGTACCCAGTCAACGACCCGCCACACAAACGCTAATGATCTCTACGATGCTCACTTATTGTTAGAGGCTTCGTGTCTGCGCAGCGAACTAGATGAGATTCTAAGATCACCCTCAAAGTCGTCGAACAAATCAAGGCAACGTTTTACCAGTGAATCATCTACACAATTTTTAACTGAACAATCAGAAGAAGAACAACATTTGATAAAAATAGAACCCACATCGCCTGATCTAAGGGAAATTGTTAATGGTGCTAGTTCGGTTAATACTAGTGCAGCACAAGGAGACCTGGAATTGGAAGTTACCTCCAGTAAAAGTGGTAGATCTAAATCGTCCAGATCTCAAAGAGCGGTAAATTCAAATCGTAAATATTTAGAATTTACCGGTGATATAAGCCCTACTGAGACCTCTAATCTAAACAAAAGAGCCGCCTCATCACTCTCAACAAAGTCTTCAAAATCTGCCCGCACCGAACCAGCCAAATCTGTGCAAAACTCTACAACTTCATATTTAGATTACACAATGGTGGATACATTTAATACGGTTACAAGTTCCTCGGCGAATAATAACAATTCATTTGCTTCTATCTCGGCAGTGGTTTCAGCAGCCGATGCTTCGGCAGCGGCCCAACAAAACTCCTCTGCAGCTGCTGTGCGTAAACCTCAACGTTATTTTGAATGTGAAATGTGCAGCGCCATATTTTCAGATCGTGCTCAGCTATTGGATCATGTGCCCATACATATTTAA
Protein Sequence
MDNHGYGGIQWIQHHSGNHSSHAGDMKTAGQLMIDPQPPREEDLMASANSSSDYMATEDETDSATIAQIAAENLIFMARDGQMMTEIITNTTTDANGTVVVTASDGEQIDCDAIMEQAALIQQHEDAGGGVYSVEHFSENTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSSSQVLLDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLMNHMVAHQTDRPHLCKLCGARFLRRQDLINHLKGHAEEPTEPQMDDSDFIHFVTDTTSSSQRTSNDHYYEQDWSVPEDSVTIPTKSSRKHQQQPQQLQHITSISNQQIMMENTITSSSPQDVLTTTQTTTAPPRGRISRLKPKEDTSYVVEVPNNCSSSEMIISSAYSIVECDTLSANTAAVKLSQDNTPALHENDEEHNVLHYPVIDDSKPFVCQQCGLAFSREKAMLSHTKTHRNDSPFECPQCNELFWDQNSLQDHQKTHQFEESNSEYDPNEGEDETQTESESEQQLYGEFYCSECGMSFHRQDLLKRHSKNHPAGNVTMGQSAHNGMESRDQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGESFFEETTIKKHLQSQHPNEITENSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVQCDVCHEEFPDGRTLSNHRHSHSATSAGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAKRGTYYCTVCGAELYSSGDLIQHLIQHSDMNTAMQRQPVTGPRKYKRRRKLKPHELARLKREVKHNGGTGSDIDLSDFDIDNVDDLLAMTTDSNTATETVTTGHEPTVSLPGKATKRKNVSATINTESNNTNKSKATINKNNKSHILEDQEDFDLDVGIDDDELKKQRYNSTSSDKIWPAKQTDDTYKSLLSNLETTLQSIDTLVVGPSTKSSHTIENNMLETQQRQTKRKIKQESTSTAQRTQQVQLTRVDKDPSTTTNGRGRKSKTGTKQTKGPQMIHTEKSTTTTTDNGGGSATGKKKSKSIITRTQTTAIDLLPKTSAIVDDYDIISPALQPPKQISSSPLHIKQEQDNHKHNYHHHPQQHHLMKNPPNTNHTTSARTQSTTRHTNANDLYDAHLLLEASCLRSELDEILRSPSKSSNKSRQRFTSESSTQFLTEQSEEEQHLIKIEPTSPDLREIVNGASSVNTSAAQGDLELEVTSSKSGRSKSSRSQRAVNSNRKYLEFTGDISPTETSNLNKRAASSLSTKSSKSARTEPAKSVQNSTTSYLDYTMVDTFNTVTSSSANNNNSFASISAVVSAADASAAAQQNSSAAAVRKPQRYFECEMCSAIFSDRAQLLDHVPIHI