Basic Information

Insect: Tachina fera
Gene Symbol: zfh1
Assembly: GCA_905220375.1
Location: LR999963.1:39026674-39034797[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00011 0.013 17.3 0.9 1 23 195 217 195 217 0.95

2 15 0.22 26 6.9 1.9 3 23 225 245 223 245 0.95

3 15 0.0003 0.035 15.9 0.5 1 23 413 435 413 435 0.98

4 15 0.0047 0.54 12.1 0.3 1 23 441 463 441 463 0.98

5 15 0.0013 0.15 13.9 4.6 1 20 495 514 495 517 0.94

6 15 0.015 1.7 10.6 0.3 1 23 537 559 537 559 0.94

7 15 0.022 2.6 10.0 0.4 1 23 565 588 565 588 0.97

8 15 0.46 53 5.9 0.4 5 19 599 613 596 614 0.91

9 15 0.00028 0.032 16.0 5.6 1 23 623 645 623 645 0.97

10 15 0.062 7.1 8.6 1.7 2 23 651 672 650 672 0.97

11 15 8.7e-05 0.01 17.6 0.2 1 23 681 703 681 703 0.98

12 15 0.0082 0.94 11.4 0.2 3 23 711 731 709 731 0.97

13 15 9.8e-05 0.011 17.4 0.5 1 23 737 759 737 760 0.95

14 15 0.0062 0.71 11.8 0.0 1 23 770 792 770 792 0.96

15 15 1.2 1.4e+02 4.5 0.2 1 20 1368 1387 1368 1390 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00011	0.013	17.3	0.9	1	23	195	217	195	217	0.95
2	15	0.22	26	6.9	1.9	3	23	225	245	223	245	0.95
3	15	0.0003	0.035	15.9	0.5	1	23	413	435	413	435	0.98
4	15	0.0047	0.54	12.1	0.3	1	23	441	463	441	463	0.98
5	15	0.0013	0.15	13.9	4.6	1	20	495	514	495	517	0.94
6	15	0.015	1.7	10.6	0.3	1	23	537	559	537	559	0.94
7	15	0.022	2.6	10.0	0.4	1	23	565	588	565	588	0.97
8	15	0.46	53	5.9	0.4	5	19	599	613	596	614	0.91
9	15	0.00028	0.032	16.0	5.6	1	23	623	645	623	645	0.97
10	15	0.062	7.1	8.6	1.7	2	23	651	672	650	672	0.97
11	15	8.7e-05	0.01	17.6	0.2	1	23	681	703	681	703	0.98
12	15	0.0082	0.94	11.4	0.2	3	23	711	731	709	731	0.97
13	15	9.8e-05	0.011	17.4	0.5	1	23	737	759	737	760	0.95
14	15	0.0062	0.71	11.8	0.0	1	23	770	792	770	792	0.96
15	15	1.2	1.4e+02	4.5	0.2	1	20	1368	1387	1368	1390	0.93

Sequence Information

Coding Sequence: ATGGATAATCATGCCTATGGGGGAATACAGTGGATACCACACCACTCAGGTAATATGTCTTCACATGTTGGAGATATGAAAACTGCGGGTCAGCTACTTATTGATCCCCAGCCACCGCGTGAGGAGGATCTAATGGCCAGTGCCAATTCGTCATCGGACTTCATGGTTACCGAGGATGATAATGACTCAACAACAACTGCGCAAATTGCTGCTGAAAACCTCATTTTTATGGCACGCGACGGACAAATGATGACTGATATAATAAGCCACGATACGAATGCAACTGTAGTGGTGAGTGCAAGCGACGGCGAACAAATTGACTGCGATACAATTATGGAACAGGCTGCCTTAATACAACAACATGAAGATGCTGGTGGAGGTGTATACACTGTGGATCATTTTGTCGAGAATACACCACAAATGGTAACAGAGGAGGTCATCACTGATGATTGGGTACAACATCAAGGTGAAGAAAgagTTGAAATACCAGCAGAACAAATTATTGGTTCTAGTTCTCAAGTGCTATTAGACATTGAAGTCCCTTTGCCAACCGTTCAAGATGAATACACTGCCCTGCGACCTTATCCCTGTGACTTTTGTAGCCGACGTTTCCGTAAGAAAGCCAGTCTTACTAATCACATGGTAGCCCATCAAACCGACAGGCCGCATTTGTGCAAATTATGCGGTTCCAGATTTTTAAGGAGGCAAGATCTTATTAATCATCTCAAGGGACATGCTGAAGAACCAACAGAACAACCACACATGGATGATACTGTtttcatgcatttcgttgctgatACTACATCTGCTACACAACGTACTTCCAATGATCATTATTATGAGCAGGATTGGAGTGTACCCGATGATTCGGTGACCATACCAACAAAATCTAGTCGTAAACAACAATATACTACCTCTGTTTCTAATCAACAACACGCTTTGatggaaaataacataatgcCTGCTTCCTCTGATATGGCAACAGCGCCACCTACAAGAGGACGTATAAGTCGCCTGAAGCCCAAAGATGACACTTCCTACGTAGTGGAAATGCCAAATAATTGTGCAACGAGTGAAATGATTATCACTTCCGCTTACAGCATTGTAGAATGTGATACTTTGTCTGCCAATACGGCAGCAGTTAAACTGTCTAATGATAGTACAACTGCTGCTCTACATGAAAATGACGAAGCGCAAAATGTCTTGCCGTACCCCATAATTGATGATAGCAAACCATTCGTGTGTCAACAGTGCGGTTTAGCCTTCTCAAGGGAAAAAGCTATGCTTTCACATACaaagACCCATCGTAATGATTCTCCATTTGAGTGCCCTCAATGCAACGAACTGTTTTGGGATCAAAATAGTTTGCAAGACCATCAAAAATCTCATCAGTTTGAGGAGAGCAATTCCGAATATGATCCAAATGATGGCGAATATGAAACGCAAAGCGAATCCGAGTCGGAACAACAGCTGTATGGTGAATATTATTGCAGCGAATGTGGGATGTCGTTTCATCGCCAGGATCTCTTAAAACGCCATGGGAAATGTCATGCCAAGGGTAACGCGATTTCTGATCAATCTAACAATGGAATGGAAAGTAGAGATCAACATTGTTGCAATACTTGTGGTGAGACCTTCGCTGAAGCTTTAGACTTATTGGCACATGCCGAAATACATGCACGTTACCCGCCTTTTAAATGTGTCTTATGTGGCGAATCCTTCTTCGAGGAGCCTACCATCAAAAAACATTTGCAGTCCCAGCATTCTAATGAGCTCACAGAAAACTCTTGTATTTTATGTGGCAAAGAGTGTCGTGACCGCAAAGCCTTGATGAAACATGCTTGGGATCATTCACGAGAAAAATGTCACTCCTGTTCGAAATGTGGCAAGAACTTCCACAACAAAGCTCGACTTAAACGTCATATGGCGTCGCATCGTGATAAGTCCGTACAATGCGATGTTTGCCATGAAGAATTTCCCGATGGTCGAACTCTATCCAATCATCGTCATTCACACAGTGCCACCTCAACGGGCAAACTATTTCCCTGCTTGGAATGTGGCAAAACATTTGGCTCACGAAGCTCCCAACAAATACATGTGCGCATACACACTGGGGAAAGGCCATACGGTTGCCGCTTTTGTTGGAAAGCTTTTGCCGATGGCGGTACACTGCGAAAACATGAGCGTATACATACAGGAGAAAAGCCGTATGCATGTTCTGTTTGTCCTCGCGCTTTCAATCAACGTGTGGTTCTCAGGGAGCATATACGTTCGCACCATTCGGGCTTGGATGCCAAGAGAGGCGTTTACTTTTGCACGGTCTGCGGCGCCGAGTTATCGTCGTCCGGAGATTTGATACAGCATTTAATACAACACAGTGATATGAATACAGCAATGCAAAGGCAACCAGTGaCTGGTCCTCGTAAATATAAACGCCGACGAAAATTAAAGCCTCACGAACTTGCACGTCTCAAACGTGAAGGCAAAAATGATGGTGGTCCTGGTAGTGACATTGATTTGTCCGACTTTGATATAGACAACGTCGACGATTTGCTAAACATGGCTGCAGATAACCACAATGCCCCTGAAACAACAGCCGGTAATCAAGATCCGCCACTTATTCCTCAaggaaaatcaacaaaaaagaaacaaatagcaAGTACTACACAGGCCGaaatcaataacaaaaataaagctACCCAAAATAAGACTAAATCACGTCGTTTAGAAGATCACGATGATTTTGACTTAGATGTGGGCATCGATGATAATGCAATGTGTAAACAACGGTTCAACTCTAGCAGTAGCGACAAAATTTGGCCAACAAAACAGACTGATGACTCCTATAAATCATTGCTTTCGAATCTAGAAACAACTCTTCAAAGTATAGATACTTTAGTTGTGGGACCATCAACTAAGTCCACGACTATTCAGGAAAATAGATTGTCAGAGACGCAGCAACGCCAAACAAAGCGTAAAGTGAAACAGGAAAAAACATCTACGTCTCAGAGAACACGACAGGTGCAACTAAAGAGAGCAGATAAAGAAGCAATACCGTCCACTAATGCCAGAGGTCGCAAGGCGAAAACCGCTGGAACCAAACAATCCAAAGGCCCACAAATGATACATACAGAAAAATGCACTATTGCACCAAACGGCATCAATGGCGGCTTGGGAGGTTCGAGTGGGAAAAAGAAAAAGTCAATTATAAGCAGAACTTCAAATGTGGAAAAAACTTCAACCATAGTAGATGATTACGATATAATTTCGCCCGCCTTGCAGCCTCCCAAACAAATAAGCTCTAGccctttgcatataaaacaagaacaAGACAACCACAACTTTCAACACCAACTTCAACagcttcatcatcatcatcacctaATGAAAAATCCTCCAAATTCAAATCACAACACTTCTGCTCGTACACAACCAACTACCCGCCACACAAACGCAAATGATCTCTATGATGCCCATTTATTGCTAGAGGCCTCCTGTCTGCGTAATGATCTTGATGAGTTTCTTAGATCGCCTTCAAAGTCTGACAAGTCAAGACAGCGTTTTACCAGTGAATCTTCCACCCAATTTATGGCCGAGCAATCAGAAGAAGAACATCATTTGATTAAAATAGAACCAACATCACCTGATCTAAGAGAAATAGTCAATGGTGCGATCAATAATACTGCCTCCTCCCCTCAACCAGACTTGGAAATGGAAGTAGATTCTGGCAAAATtcgtagaaataataaatcttctCGAAGTCAAAGAGGGTTATCAGGTTCAAATCGCAAATATTTAGAATTTACGAGTGATGAAACCACAAGCATTAATCAAAAAAAGTCTTCATCGAAATCACTTAAATCTGCCAGAACCGAGTCATCCAACATTTCACAATCTGTTCAAAATAGCTCAACTACAAGTTCTTATCTTGATTACAATACCATGGTGGACACTTTCAATACGGTTACAAGTTCCTCATCAAATAATAGCAACTCATTCGCTTCTATTTCTGCAGTAGTTTCAGCAGCGGATGCGTCTGCAGCAGCTCAACAAATTTCCTCAGCCACTGCTGCTGGGGGCGTTCGAAAACCCCAACGCTATTTTGAGTGTGAAATGTGTTGCGCCATTTTTTCAGATCGTGCCCAACTGCTAGATCATGTAcccatacatatttaa
Protein Sequence: MDNHAYGGIQWIPHHSGNMSSHVGDMKTAGQLLIDPQPPREEDLMASANSSSDFMVTEDDNDSTTTAQIAAENLIFMARDGQMMTDIISHDTNATVVVSASDGEQIDCDTIMEQAALIQQHEDAGGGVYTVDHFVENTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSSSQVLLDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLTNHMVAHQTDRPHLCKLCGSRFLRRQDLINHLKGHAEEPTEQPHMDDTVFMHFVADTTSATQRTSNDHYYEQDWSVPDDSVTIPTKSSRKQQYTTSVSNQQHALMENNIMPASSDMATAPPTRGRISRLKPKDDTSYVVEMPNNCATSEMIITSAYSIVECDTLSANTAAVKLSNDSTTAALHENDEAQNVLPYPIIDDSKPFVCQQCGLAFSREKAMLSHTKTHRNDSPFECPQCNELFWDQNSLQDHQKSHQFEESNSEYDPNDGEYETQSESESEQQLYGEYYCSECGMSFHRQDLLKRHGKCHAKGNAISDQSNNGMESRDQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGESFFEEPTIKKHLQSQHSNELTENSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVQCDVCHEEFPDGRTLSNHRHSHSATSTGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAKRGVYFCTVCGAELSSSGDLIQHLIQHSDMNTAMQRQPVTGPRKYKRRRKLKPHELARLKREGKNDGGPGSDIDLSDFDIDNVDDLLNMAADNHNAPETTAGNQDPPLIPQGKSTKKKQIASTTQAEINNKNKATQNKTKSRRLEDHDDFDLDVGIDDNAMCKQRFNSSSSDKIWPTKQTDDSYKSLLSNLETTLQSIDTLVVGPSTKSTTIQENRLSETQQRQTKRKVKQEKTSTSQRTRQVQLKRADKEAIPSTNARGRKAKTAGTKQSKGPQMIHTEKCTIAPNGINGGLGGSSGKKKKSIISRTSNVEKTSTIVDDYDIISPALQPPKQISSSPLHIKQEQDNHNFQHQLQQLHHHHHLMKNPPNSNHNTSARTQPTTRHTNANDLYDAHLLLEASCLRNDLDEFLRSPSKSDKSRQRFTSESSTQFMAEQSEEEHHLIKIEPTSPDLREIVNGAINNTASSPQPDLEMEVDSGKIRRNNKSSRSQRGLSGSNRKYLEFTSDETTSINQKKSSSKSLKSARTESSNISQSVQNSSTTSSYLDYNTMVDTFNTVTSSSSNNSNSFASISAVVSAADASAAAQQISSATAAGGVRKPQRYFECEMCCAIFSDRAQLLDHVPIHI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00259964;
90% Identity: iTF_01399741;
80% Identity: -