Basic Information

Insect: Aphis gossypii
Gene Symbol: L
Assembly: GCA_004010815.1
Location: NW:158603-166742[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 1 79 3.5 7.0 1 23 3 25 3 25 0.97

2 21 4.3e-07 3.2e-05 23.6 5.6 1 23 31 53 31 53 0.99

3 21 5.4e-06 0.0004 20.2 0.9 1 23 59 81 59 82 0.96

4 21 8e-05 0.0061 16.5 2.0 1 23 99 121 99 122 0.96

5 21 0.0044 0.33 11.0 0.7 1 23 146 169 146 169 0.97

6 21 0.37 28 5.0 0.9 1 23 207 230 207 230 0.95

7 21 0.0026 0.19 11.7 2.1 2 23 410 431 409 431 0.94

8 21 8.8e-05 0.0066 16.4 1.6 1 23 439 462 439 462 0.96

9 21 9.9e-05 0.0075 16.2 0.6 1 23 467 490 467 490 0.95

10 21 0.00039 0.03 14.3 0.8 2 23 540 561 539 561 0.96

11 21 0.05 3.7 7.7 3.6 1 23 565 587 565 588 0.96

12 21 0.64 48 4.2 0.2 3 23 632 654 631 654 0.86

13 21 0.00073 0.055 13.5 4.6 2 23 668 689 667 689 0.96

14 21 0.0016 0.12 12.4 0.3 1 23 699 721 699 721 0.98

15 21 0.33 25 5.1 3.3 2 23 729 750 728 750 0.97

16 21 0.0017 0.12 12.3 0.1 2 23 825 847 825 847 0.97

17 21 0.083 6.2 7.0 1.3 1 23 851 873 851 873 0.97

18 21 0.11 8.5 6.6 0.1 2 23 885 906 884 906 0.95

19 21 0.0049 0.37 10.9 0.0 1 23 914 937 914 937 0.96

20 21 0.34 26 5.1 0.2 1 23 944 968 944 968 0.94

21 21 7.8 5.9e+02 0.8 4.3 1 22 995 1016 995 1018 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	1	79	3.5	7.0	1	23	3	25	3	25	0.97
2	21	4.3e-07	3.2e-05	23.6	5.6	1	23	31	53	31	53	0.99
3	21	5.4e-06	0.0004	20.2	0.9	1	23	59	81	59	82	0.96
4	21	8e-05	0.0061	16.5	2.0	1	23	99	121	99	122	0.96
5	21	0.0044	0.33	11.0	0.7	1	23	146	169	146	169	0.97
6	21	0.37	28	5.0	0.9	1	23	207	230	207	230	0.95
7	21	0.0026	0.19	11.7	2.1	2	23	410	431	409	431	0.94
8	21	8.8e-05	0.0066	16.4	1.6	1	23	439	462	439	462	0.96
9	21	9.9e-05	0.0075	16.2	0.6	1	23	467	490	467	490	0.95
10	21	0.00039	0.03	14.3	0.8	2	23	540	561	539	561	0.96
11	21	0.05	3.7	7.7	3.6	1	23	565	587	565	588	0.96
12	21	0.64	48	4.2	0.2	3	23	632	654	631	654	0.86
13	21	0.00073	0.055	13.5	4.6	2	23	668	689	667	689	0.96
14	21	0.0016	0.12	12.4	0.3	1	23	699	721	699	721	0.98
15	21	0.33	25	5.1	3.3	2	23	729	750	728	750	0.97
16	21	0.0017	0.12	12.3	0.1	2	23	825	847	825	847	0.97
17	21	0.083	6.2	7.0	1.3	1	23	851	873	851	873	0.97
18	21	0.11	8.5	6.6	0.1	2	23	885	906	884	906	0.95
19	21	0.0049	0.37	10.9	0.0	1	23	914	937	914	937	0.96
20	21	0.34	26	5.1	0.2	1	23	944	968	944	968	0.94
21	21	7.8	5.9e+02	0.8	4.3	1	22	995	1016	995	1018	0.87

Sequence Information

Coding Sequence: ATGCCGTTCAAGTGTCAATTCTGCCGGAGGCTGTTCAAACACAAGCGCAGCCGAGACCGGCACGTGAAATTACACACGGGGGACAAGAAGTACAAGTGTACTCAATGTGACCATGCTTTTTCAAGGAGCGATCACCTGAAGATCCACATGAAAACGCACGACAATCAAAAACCGTTCCAGTGTACGGTTTGCAACAGAGGTTACAGCACGGCGGCCGCGCTAACGTCACACATGCAGAACCATCACAAACGGGCTGCGGAACGGGCCAACTCACCGCAGATATCCGGCCCCTCGTACAAGTGTCTACAGTGCACGCAGATATTCCGTAAACCCGACGAGCTTCAGAATCACACTGCGACTCATCATCTCGGCGAGCAACTGTCGTCCAACTCCCGGAGCTCGAAACGTTCGACACCGCCCAAAACGCCCAACCAGTACATTTGCATGTACTGCACCAAAGAAGTGTCCAGCATGGACGCACTGCAACAGCACTTCCAGACCAAACACTCCGCGATCGTCAACGGCAAGCCGCAAGAGGACGTCTTCTCGGCCGTACCGCCGGCAGCCGCGTTCCCGTGGCTAAACTTTGCCGATTCACCAGCCCTAGCACTGCCCCCGTACTCGTGCCGGTTGTGCTTGAGCCAATTCCCGTCCGTCACTTCGTTACAGAAACACTTTACGACCGCCCACTATCTGAGTTCCGTCCTCAACAACAACATAcagaacaacaacaacaacaacagcagcaacagcaacaacaacaacaacaccaACGGCTGCAAAGGCGTAGGTAGCGCGATGCCCTTGTACAACTGGCCGGTAATAACCGGAGCGAACGGTTACCACAACCACCTCCAACGACACTCGACGTCGGGCGGTAGTTTGTTGCCCGAAGAAACCGTCCAGACGGGTCCCACAGACTTGTCGCTGTCGTCGTCCAAGCATGGTGGAGGCGGCGGCAAACACCATCACTCATCGTCGGGCAAGCACAAGTCGGCCGACGACCAGCGGAACCACGCGACCAGCAAAAAGTCCCGTTCGTCGCCGAGCCGCGATCCGTCGGCGGCCGACCAGCGTCACATAAAACAAGAACGCCACAACGCTTATGACGGCAAACATCAGCAGCTGCAACCGACCGCGGCTCGACCTTCCTCGCAGATCGGCGTCTCCGGcgtcaacaacaacaacaacaacaacattcACGCCAACAACAACAAGATCCAATTGCCGTGTCCGCACTGCCATCTGACGTTCGCGCACTTCGAAGACTATCAGCAGCACGTTATCGGTCACTTTCTCATGGCCGCCGCCGAGTACTCGTGCCAGGAGTGTTCCACGTCGTTCGCCACGTCCGAACACGTACAGAAACACCTGATGGAAACTCACGCGCAGAACTTTTACCGGTGCATGTTGTGCAAAGAAGTGTTCCCGACCAAGTCGGCCCTGAAGGTGCACTTCAGCATGAACCACGGCAGCGAACACCGGATGTTCCGCTGCAACAACTGCACGGGGCTGTCCCGGCCGCTGTTCCAAACGGAAATAGAGTTCATCGATCATCTGCGCAACGCCCATTATTCCGCGAGATCACCTCCGCCGGTCCAAGCAAATTTGATGCTTAGGTGTTTGGTATGCCACGCTACGTTCAACACGCAATCCGATATGGAACAACATTTAGCTAGTCACTCCAAACAATTCCAATGCCAATTTTGTTCGGAAGCGTTCCACATCGAGTTCTTGTTGGACAGACACATACAAACGCATCACAGTTCGAGTATTTTAAGTCACCTCAACCGGAACCACAGGGAATCGCCAAATTCCATGTGTACGTCACCCACGTACATTTCCAGGACGGCGGACGGCGGTAAACATCCGGCGGAAAACGGCACGAACGCTTGTGATATATGTGAGAAAAATGATTTTCGAAACGAATTGGACTTGATTGCCCACAAAAGAACAATGCACCAGGTGAAACCTACGAATCTTTCGACAAAAGTGAGCTTACATTGCGCATATTGTAACGAAAACTGCAAATCGAGAACAGAATTGGAAAACCACATGAAGACGCATTCACAACACGGTTCAAACGTAGGAAAACACAAGTGCAATATTTGTGACGAAATTTATCAGTCCGCAATCAGCTTAGCCGAACACAAACTCACTCATTGCAAGGTCGCTACGAGTACCGTGTGTAGTCACTGCAAAATGATCATTGATAACGAGGATCAGTTCCATCAACATCTCCAGAAACACTGCAACCCGGCGAACGCGAACAGCGGCCAAGTGGCGTTCCCCACGTCGTGCATAATATGCAGGCAAACGCTCGTTTCAGACATCGAAGTGAAGGTGCACGTACACTATCACCTGTCCCGAGTCAAAGAATCTCCTGCCGTGTGTGGCAACTGCAACCGGTACAAGCGGTCAGCGTCGTCTCCGTGCGACGGCTGCAACCCGACCAGAAACAGTGCGGCGGAACGATGTCCTGACTGCGGTGCGGCGTTCGACGCTTTCGGCGCTCTGCAACACCACCTGACCACCGTCCACAGGAAACCTTTTCACTGTTTCAAGTGCAAGATCGGATTCGAATCGCAGCAGGAAGCCACGATTCACCTGGGCACGCACCTGGCCACGCTCAACGGTTCCGTGGACGGCATCGAGTGCGGCCTTTGCCCGTGCGTGCTGCCCACGACCAACAGTCTCCAGACTCACCTGATCGAGCACACGTTCGCCGGCTGCAAAGCGTTCACGTGCTACTTGTGTTCGGCCATATTCACCGCGCCCACCGGACTGCAGGCGCACATGACCGTCGACCACTCGGCCGAAACGCCGCCGTACGACTGCCCCAGGCCCGGGTGCCAGGCCAAGTTCTTCTTCACCGCCGAACTGGACAGGCACACGCTCGAGCACCAGGGACAGGACGTCCTGGCCAAcATGAATTTTTACAAGTACCAAAACAAACTTATGTCCATCTGCGAAAAACTGTCGTTCAAGTGTGCCGAGTGCTATCAGAGCTTTTTGACACAAACCGACTTACAGTGTCACGTGTACGATCACCATCGGCAACCACAAACGGATGCACCGCCGGCGGGATCGGAAACGATGGACGTCAAACAGGAAATGAGCGGATGCGCGGTTAACGGTAACGCGGAAAAGCGGCCTTTGGACGGATGCGAACGGACCGAGAATCCGATCAAAGTGGAGGAAGATGGGGACGAAGTGAGCGTGAAAACGGAACATCGCGAAAGAGACGACGATGACGAAGAGATGATTGACGTGGTAGAGAACAATCGCGACGAGCCGAAGTCGGGCGAAGACGAAAACGACGTGGATATGCATTGA
Protein Sequence: MPFKCQFCRRLFKHKRSRDRHVKLHTGDKKYKCTQCDHAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYSTAAALTSHMQNHHKRAAERANSPQISGPSYKCLQCTQIFRKPDELQNHTATHHLGEQLSSNSRSSKRSTPPKTPNQYICMYCTKEVSSMDALQQHFQTKHSAIVNGKPQEDVFSAVPPAAAFPWLNFADSPALALPPYSCRLCLSQFPSVTSLQKHFTTAHYLSSVLNNNIQNNNNNNSSNSNNNNNTNGCKGVGSAMPLYNWPVITGANGYHNHLQRHSTSGGSLLPEETVQTGPTDLSLSSSKHGGGGGKHHHSSSGKHKSADDQRNHATSKKSRSSPSRDPSAADQRHIKQERHNAYDGKHQQLQPTAARPSSQIGVSGVNNNNNNNIHANNNKIQLPCPHCHLTFAHFEDYQQHVIGHFLMAAAEYSCQECSTSFATSEHVQKHLMETHAQNFYRCMLCKEVFPTKSALKVHFSMNHGSEHRMFRCNNCTGLSRPLFQTEIEFIDHLRNAHYSARSPPPVQANLMLRCLVCHATFNTQSDMEQHLASHSKQFQCQFCSEAFHIEFLLDRHIQTHHSSSILSHLNRNHRESPNSMCTSPTYISRTADGGKHPAENGTNACDICEKNDFRNELDLIAHKRTMHQVKPTNLSTKVSLHCAYCNENCKSRTELENHMKTHSQHGSNVGKHKCNICDEIYQSAISLAEHKLTHCKVATSTVCSHCKMIIDNEDQFHQHLQKHCNPANANSGQVAFPTSCIICRQTLVSDIEVKVHVHYHLSRVKESPAVCGNCNRYKRSASSPCDGCNPTRNSAAERCPDCGAAFDAFGALQHHLTTVHRKPFHCFKCKIGFESQQEATIHLGTHLATLNGSVDGIECGLCPCVLPTTNSLQTHLIEHTFAGCKAFTCYLCSAIFTAPTGLQAHMTVDHSAETPPYDCPRPGCQAKFFFTAELDRHTLEHQGQDVLANMNFYKYQNKLMSICEKLSFKCAECYQSFLTQTDLQCHVYDHHRQPQTDAPPAGSETMDVKQEMSGCAVNGNAEKRPLDGCERTENPIKVEEDGDEVSVKTEHRERDDDDEEMIDVVENNRDEPKSGEDENDVDMH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00973245; iTF_00135616; iTF_01346628; iTF_01347466; iTF_01167918; iTF_01038682; iTF_00463534; iTF_00019605; iTF_00134815;
90% Identity: iTF_00135616; iTF_00134815;
80% Identity: -