Basic Information

Insect: Anopheles minimus
Gene Symbol: Bcl11b
Assembly: GCA_000349025.1
Location: KB663733.1:450809-480571[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00016 0.0089 16.0 2.1 1 21 199 219 199 220 0.95

2 16 1.3e-06 7.5e-05 22.5 4.3 1 23 641 663 641 663 0.99

3 16 4.1e-07 2.3e-05 24.1 0.5 1 23 669 691 669 691 0.99

4 16 2.5e-05 0.0014 18.5 0.1 1 23 697 719 697 719 0.98

5 16 3.9e-05 0.0022 17.9 0.6 2 23 725 746 724 746 0.96

6 16 2.6e-07 1.5e-05 24.7 4.1 1 23 752 774 752 774 0.99

7 16 9.5e-05 0.0054 16.7 1.7 1 23 840 862 840 862 0.97

8 16 6.3e-06 0.00035 20.4 2.5 2 23 869 890 868 890 0.98

9 16 2e-06 0.00011 22.0 0.8 1 23 896 918 896 918 0.98

10 16 2.5e-06 0.00014 21.7 0.1 2 23 924 945 923 945 0.98

11 16 1.8e-06 0.0001 22.1 2.1 1 23 951 973 951 973 0.99

12 16 3.4e-07 1.9e-05 24.4 2.3 1 23 1021 1043 1021 1043 0.99

13 16 3.5e-07 2e-05 24.3 0.9 1 23 1049 1071 1049 1071 0.99

14 16 4.9e-05 0.0027 17.6 0.3 1 23 1077 1099 1077 1099 0.98

15 16 4.6e-06 0.00026 20.8 0.3 2 23 1105 1126 1104 1126 0.97

16 16 3.2e-06 0.00018 21.3 1.2 1 23 1132 1154 1132 1154 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00016	0.0089	16.0	2.1	1	21	199	219	199	220	0.95
2	16	1.3e-06	7.5e-05	22.5	4.3	1	23	641	663	641	663	0.99
3	16	4.1e-07	2.3e-05	24.1	0.5	1	23	669	691	669	691	0.99
4	16	2.5e-05	0.0014	18.5	0.1	1	23	697	719	697	719	0.98
5	16	3.9e-05	0.0022	17.9	0.6	2	23	725	746	724	746	0.96
6	16	2.6e-07	1.5e-05	24.7	4.1	1	23	752	774	752	774	0.99
7	16	9.5e-05	0.0054	16.7	1.7	1	23	840	862	840	862	0.97
8	16	6.3e-06	0.00035	20.4	2.5	2	23	869	890	868	890	0.98
9	16	2e-06	0.00011	22.0	0.8	1	23	896	918	896	918	0.98
10	16	2.5e-06	0.00014	21.7	0.1	2	23	924	945	923	945	0.98
11	16	1.8e-06	0.0001	22.1	2.1	1	23	951	973	951	973	0.99
12	16	3.4e-07	1.9e-05	24.4	2.3	1	23	1021	1043	1021	1043	0.99
13	16	3.5e-07	2e-05	24.3	0.9	1	23	1049	1071	1049	1071	0.99
14	16	4.9e-05	0.0027	17.6	0.3	1	23	1077	1099	1077	1099	0.98
15	16	4.6e-06	0.00026	20.8	0.3	2	23	1105	1126	1104	1126	0.97
16	16	3.2e-06	0.00018	21.3	1.2	1	23	1132	1154	1132	1154	0.98

Sequence Information

Coding Sequence: atgaaggaAGCCTCAATGATCGACGCATTCGATACGACGGATTTTAATCCAGAACTGATCCTGTCCAGCGTGTTTCTGGACCAAGGGCTAGATTTCGTCACCAACATTGACGATCTCGGTGACAATATCATCGCATCCGatctgctgcagcagctggGCAGCTCGGTATTCTACACCGAGCCGCCCATCGCAACGAATGGCAACAACGGTGGAAGTGTGGGGCTCTGTGgggccaccaccaccaccacacagcAACATCATGGCCAAAATCAACAAccccagcaacagcaacatcatcatcaacagcagaTTTTAtcgcaaccaccaccagcacttCTTTCGGCGAAAGCGCGTATGACAATTGAGAAACCCACCGATGAGATGCGCTACGACACATTCGGAAGTGATTATGCAAAGCCACAACTTGTGCCGGCCGTACCGCTTACAATGCCGATGGTGCAACAaattcaacagcaacaacaaccggtATCGTCGGTAGCTACtactcagcagcagcagcaacaacaaccgtgCAAATGTGAATTCTGCGAGTATCTTCAAGCCAACCGGATATCGCTTACGGGTGATCACTCGTTCCAGTGTGAGTTCTGCGGAGAAGGTTTCTCCAATCAGACCAGCTTCAACCGGCATCGCTGCGGTAGTACGGATATACAAATATATCGGTGCGAAAACTGTCGGCAGGAGTATGGAAGCTCGAGAGCTGTCTCCAGCATTGGCAACTGCGAGCCAAGAGATAAATGCGATATCTGCAATCGAAACATCGTACAGTCTTTGCCGGAAGAACAGGCGGCCTATGGTCCTGCGATGGTAGCAGGAAGCTCTTCAATAAGTTCCCAAACCACACCGGCATCCGTGTCGGATGTAACGATCGATGGATCAGTTTCCCTGCTTGTTACTTCGCCTGAGGTGTCCAACGGAAGCGTTAGTGATCTTAGTGTGAACGTCAACGTGCGGTCCATGGTGAACAGTCCCATCGAGCAGCACGATCTAAGCAGCATTGATCCGTTCGGGTCAGACAGTGAGTGTTTAGGTCAGTTCTTTGCAACCGAGGCGTCCTCCACCTCGCCCTGTACGGCTAGCACTACCAGTAACATACAGTGTACACCAATGCCAACGAGTGCCAACATCGGGAGCCTGCTTCCTGCCGCTGCGCTGAACCCTCCGGAGTCGGCGAAGACGTACTTTGTGCTGGGAAACGTAGAACAGTTGCAACAATTCCACGCGGCCACagcgcaacagcaacagcaacccaCGAACAACCTTCCGACGATCACCAATAGCTTCCATCCGCTTCATCTGCCACCTCCCGGACCTGGAcctcatcagcagcagcaactgaTACCTCTCTCGCTGCAGAATGCCGTACCGGTTACGGCCGGGTCGCATCTGCCCAGCGAGCACGAGGTCACTAGTCTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAACCCTATGCCAAATCGCCTAACCAGGACCACGCCAAGACGGAACTACCAATCCAAGAGACAATCGTTGACACTAGCACCGGCATCAGTACGATCATTCCGCTACAACAGTTCGGTTCGGGCGGATTACCGAGGGATGACGCTTCACTTAGCCGCGCACTGTTGGCGCATGGCGTTGCACAGCATCTGCAGGTTCAGCAACaagcacagcaacagcaactccaccatcaccattccGCTGGTGTATCACAACTTAAGCCACATCTggatgaagaggaagaagGTAAATGTGATTCGTCATCTCCATCGCTTGGAATATTCGTCGGTGGTTCCACCGGAGCAACGAATGGCGTAGAAAAGGGGTCTCAAAAACCACAGTCTTCTCTCGTCGGAAGCGTTAATGTGGAACGGCCCTACAAGTGTCACATCTGCGAACGTTCGTACCGGAATCAGAAGAACCTGAAGTCACATCTGAAGGTGCACGAGGGCATTCGGGCGTATCAGTGTGAAATTTGTGGTAAGAATTTCTCCGGCTCCAGCTATCTGGTGATCCACCGACGGCGCCATACCGGTGAGCGTCCGTTCAAATGCGTTACCTGCGGAAAGGCGTTTGTCGACTCGCGAGCGCTAGCCGTGCACGCGCGCTTACACAGTGGGGAACGGCTCAAGTGTGAGAAATGTGAGAAAACTTTCTCCAGCGTGAGTGCGCTCACCGTGCACAACCGGCTGCACACCGGCATCCACCCGTACAAATGTGAACTGTGCGGCAAAACATTTCCCCAGTACAACAACCTGAAACATCACATGAAGAAACACGAGCAACCGAATGGTTCCGAGGGTCAGCCCCAGGGAGGGACGAGTCCACCGTGTGGATCGGGCACAGTGTCTAATGGCGTTAGTACGACGAGCGGTTCCGGGACGGGAACGGGACGGTTACGCTCGACACCGGAAACGAAACTCAATGGAGCGGTACATATGGTGGCGAGCTCGACTACCGGCTCACCGTTCGAGTACAAATGTCACATTTGTAGCAAACTGTACAAATCTGCCGACGACTTGCAGGAACACCTGAGTCAGCACGGGAAAGATCGGCCAAATCAGTGCGAGTTTTGTTCGAAGGTGTTTCCGCGATCCTCGCATCTCATCATCCACCGGCGACGGCATACGGGTGAGCGACCCTTCAAATGCAAATACTGCGACAAAGCGTTCGTGGATTCGCGTGCCCTCTCCGTCCACACGCGGCTGCACACGGGCGAACGGGTAAAGTGCGAGATCTGCGAGAAAACGTTCGCCAGCTCCAGTGGACTCATAGTGCACCGGCGCATCCACACCGGGGTGCATCCGTACAAGTGTGACTACTGCGAAAAGTCTTTCGCCCAATCAACCGCACTCAAGTACCACCTGAAAAAGCACGACACAGCTCTGCTGCCCACGACGACAACGCCCGAAACTGCCGACTCACGGCTTTCGGCACGACCCGCACACGGTACCGTCGGTGATCTAGGCCAGTGTCCATCGTATGGCGATGACTCGACAGCGAACGGGAACGATCGGTACAAGTGCACCGTGTGCAGCAAGGTGTTCCGATCCTCCGAGTACCTGGTGCGACATCGGCGAACGCACAGCGGCGAGCGACCGTATCAGTGCGAGATTTGTGGCAAAAACTTCTCCACCATGAGCTACCTTGTGATCCACCGGCGTCGGCATACGTCCGAGCGACCGTACAAGTGTACTTCCTGCGAGAAAGCGTTCGTCGATTCGCGGGCCCTGCAGGAACACGCCCGGTTGCATACGGGCGATCGGGTGCGTTGCGAGATTTGCCAAAAAACCTACTCGAGCGTTAGCAATCTGATCGTGCACCGGCGCATCCACAGTGGCATCCATCCGTTCGAGTGCGACAGCTGCGGGAAATCGTTTGCGCAAAAGAATGCCCTCAAGTATCACCTCAAGAAACATAGCAAACAGGATCAAACAGAGCCGGTGGGTTAG
Protein Sequence: MKEASMIDAFDTTDFNPELILSSVFLDQGLDFVTNIDDLGDNIIASDLLQQLGSSVFYTEPPIATNGNNGGSVGLCGATTTTTQQHHGQNQQPQQQQHHHQQQILSQPPPALLSAKARMTIEKPTDEMRYDTFGSDYAKPQLVPAVPLTMPMVQQIQQQQQPVSSVATTQQQQQQQPCKCEFCEYLQANRISLTGDHSFQCEFCGEGFSNQTSFNRHRCGSTDIQIYRCENCRQEYGSSRAVSSIGNCEPRDKCDICNRNIVQSLPEEQAAYGPAMVAGSSSISSQTTPASVSDVTIDGSVSLLVTSPEVSNGSVSDLSVNVNVRSMVNSPIEQHDLSSIDPFGSDSECLGQFFATEASSTSPCTASTTSNIQCTPMPTSANIGSLLPAAALNPPESAKTYFVLGNVEQLQQFHAATAQQQQQPTNNLPTITNSFHPLHLPPPGPGPHQQQQLIPLSLQNAVPVTAGSHLPSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGISTIIPLQQFGSGGLPRDDASLSRALLAHGVAQHLQVQQQAQQQQLHHHHSAGVSQLKPHLDEEEEGKCDSSSPSLGIFVGGSTGATNGVEKGSQKPQSSLVGSVNVERPYKCHICERSYRNQKNLKSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCVTCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYKCELCGKTFPQYNNLKHHMKKHEQPNGSEGQPQGGTSPPCGSGTVSNGVSTTSGSGTGTGRLRSTPETKLNGAVHMVASSTTGSPFEYKCHICSKLYKSADDLQEHLSQHGKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPETADSRLSARPAHGTVGDLGQCPSYGDDSTANGNDRYKCTVCSKVFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHSKQDQTEPVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101810; iTF_00101094; iTF_00107118; iTF_00104527; iTF_00104526; iTF_00093595; iTF_00095774; iTF_00108534; iTF_00097913;
90% Identity: iTF_00097913;
80% Identity: -