Aara007600.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles arabiensis
Gene Symbol
Bcl11b
Assembly
GCA_016920715.1
Location
NC:2772827-2800668[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00017 0.0083 16.0 2.1 1 21 195 215 195 216 0.95
2 16 4.4e-07 2.1e-05 24.2 4.2 1 23 663 685 663 685 0.99
3 16 4.7e-07 2.3e-05 24.1 0.5 1 23 691 713 691 713 0.99
4 16 2.9e-05 0.0014 18.5 0.1 1 23 719 741 719 741 0.98
5 16 4.5e-05 0.0022 17.9 0.6 2 23 747 768 746 768 0.96
6 16 4e-07 1.9e-05 24.3 4.0 1 23 774 796 774 796 0.99
7 16 4.4e-05 0.0021 17.9 2.5 1 23 866 888 866 888 0.97
8 16 7.2e-06 0.00034 20.4 2.5 2 23 895 916 894 916 0.98
9 16 2.2e-06 0.00011 21.9 0.8 1 23 922 944 922 944 0.98
10 16 2.8e-06 0.00014 21.6 0.1 2 23 950 971 949 971 0.98
11 16 2.1e-06 0.0001 22.0 2.1 1 23 977 999 977 999 0.99
12 16 2.2e-07 1e-05 25.1 2.1 1 23 1047 1069 1047 1069 0.99
13 16 4e-07 1.9e-05 24.3 0.9 1 23 1075 1097 1075 1097 0.99
14 16 5.6e-05 0.0027 17.6 0.3 1 23 1103 1125 1103 1125 0.98
15 16 5.3e-06 0.00025 20.8 0.3 2 23 1131 1152 1130 1152 0.97
16 16 3.7e-06 0.00018 21.3 1.2 1 23 1158 1180 1158 1180 0.98

Sequence Information

Coding Sequence
atgaaagaAGCCACAATGATCGATGCATTCGACACGGCGGATTTTAATCCAGAGCTGATCCTGTCCAGTGTGTTTCTGGATCCCGGACTAGATTTTGTTACCAACATCGACGATCTCAGTGACAATAGCATAGCGGCCGATCTGCTGCAGCAGTTGGGTAACTCCATTTTCTACCCAGAAACTTCAATCGCAACGAATATTAGCAACGGTGAGATTGCAGGGCTGGCCGAAACCATCCCACAGCAACAACATGcacaacaccaacagcaacaacaccacaatcatcaacatcaacagcagcagcagcagcagcaagtgctGTTGCAACCTTCCATGGTTTCGACAAAAGGACGAGACACCATTGAGAAACCCACCGACGAGATGCGCTTCGAAACATTCGGAAGCGATTACGCAAAGTCCCAGCTGACGGCGGCTGTGCCACTCACTATCCCAAtggtgcaacaacaacaacaacaacaacaatcggcGGTGGCagtccagcaacagcaacagcagacaTGTAAATGTGAATTCTGCGAGTACCTCCAGGCCAACCGGATATCGCTTACCGGCGATCACTCCTTCCAGTGCGAGTTTTGCGGGGAGGGATTCTCCACCCAGACCAGCTTCAACCGGCATCGGTGCGGGAGTACGGACATCCAGATATACCGGTGCGAAAATTGCCGCCAGGAGTATGGTAGCTCGCGTGCCATGTCCACCATCGGTAACTGTGAGCCTAGGGACAAGTGTGATATCTGCAATCGCAACATTGTACAGTCGTTGCCAGAGGAGCAGGCGGCCTACGGCCCCTCGATGGCGGCTGGAAGCTCCCCAATGTCTTCACAAACCACAGCGTCCGTGCTGTCTGACGGCACGATTGGTGGAACGGTCCACTTGCCGACGATGATAGCGACGCTAACCTCCCCCGAAGTGTCTAACGAAAGCGTCAGCGATCTCAGTGCCAACGTCAATGTAAGGTCTATCGTGAACAGTCCCATCGAACAGCACGACCTTAGCAGCCTGGATCCGTTCGGGTCGGACAGCGAGTGTCTGGGTCAGTTCTTTGCCGCTGAGCCAAGCTCCACCTCGCCCTGTACGGCTAGCAGCACGGCAACCAACTTACAGTGTCAACCAATGCCAACTAGTGCCAACATGGGGAGTCTTCTCTCCATCCCTGCACTGCACCAGCCAGAGTCAGCGAAGACGTACTTCGTGCTTGGAAATGTGGATCAGTTGCAGCAATTTCACGACatagcaacaccaccaccgccagcaacagcagagcAAGCGCCAGTGCAGCAACCACCAGCCGGCAGCAATCTTCCAACAGCGGTCACCAATAGCTTCCATCATCTTCATTTAGCGCCAGCAGGACCTGGgcctcatcagcagcagcaactgctaCCTCTCTCGCTGCAGAATGCCGCCCCCGCTACGGCCGGTTCGCTTCTGCTCAGCGAGCACGAGGTCACTAGTCTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAACCCTATGCCAAATCGCCCAACCAGGACCATGCCAAGACGGAGCTCCCAATTCAAGAGACGATCGTTGACACTAGCACCGGCATCAGTGTCATGTCGCTGCCACCGTTCGGAACTGGCGGACTGCCAAGGGACGCTGATGGTTCGCCGCTGGGCCGAACACTGATACCACCACCGCATGGTGTCGGCGTACAGCATcatctgcagcagcatcaacagccgttgcagcaacagcaacagcaccaccattCGTCCGACGTGTCGCTGATACACCGGgacgaagaagaggaaggaaaATGTGATTCGTCATCTTCACCGCTTGGATTACTGGTCGGAAGCCCGTCTGGAATAGCGAACGGTGGCGGCGAAAGAAGGCCACATCAGGCACAGTCCtccactactaccaccaccagcaccagcaccaaccCCGATCGACCCTACAAGTGCCACATCTGCGACCGTTCGTACCGCAACCAGAAGAACCTGAGGTCCCATCTGAAGGTGCACGAGGGCATTCGGGCGTACCAGTGCGAGATCTGTGGCAAGAATTTCTCCGGCTCCAGCTATCTGGTGATCCACCGGCGGCGCCATACGGGCGAACGGCCATTCAAGTGCGTCACCTGCGGGAAGGCGTTCGTCGATTCGAGAGCGCTGGCCGTGCACGCGCGCTTGCACAGCGGCGAGCGGCTCaagtgcgaaaagtgcgaGAAAACTTTCTCCAGCGTGAGTGCCCTGACTGTGCACAATCGGCTGCACACCGGCATACACCCTTACCGGTGTGAGCTGTGTGGCAAAACATTCCCACAGTACAACAACCTGAAGCACCACATGAAGAAGCACGAGCAACCGAGCGATGCAGAGCAGCTGCTGCCCCAAGCAATGGCGACCTCAACCGGTGGCCCCACACCACCGTCCAATGGGGTGAGCACTACGACGAGCGGCTCCGGTACTGTACTGGCGCGCATCAGTCTCTCGATACAAGCTGACACCACCGGCAAAGGAACGGTGCACATGATAGCCAGCTCGACCACGGGTCCGGCCTCCGAGTACAAATGCCACATCTGCAACAAGCTGTACAAATCCTCCGACGACCTGCAGGAGCACCTGAGCCAGCACAGCAAGGATCGGCCGAACCAGTGCGAGTTTTGCTCGAAAGTGTTTCCGCGCTCTTCCCATCTCATCATCCACCGGCGTCGGCACACGGGCGAGCGGCCCTTCAAGTGCAAATACTGCGACAAAGCGTTCGTTGACTCGCGCGCCCTCTCCGTCCACACGCGCCTGCACACGGGCGAGCGGGTCAAGTGCGAAATCTGCGAGAAAACGTTCGCCAGCTCGAGCGGTCTCATAGTGCACCGGCGCATCCACACCGGGGTGCATCCGTACAAGTGTGACTACTGCGAAAAGTCCTTCGCCCAATCGACGGCACTCAAGTACCATCTGAAAAAACACGACACCGCCCTGCTGCCAACCACGACCACGCCCGAGGGTGCTGATACGCGGCTACCAGCCCTGCCCCAGAACGGTGCCGCCGATGTTGGGCAATGTGCGCCCTCGTTTGGCGAGGACGCGACCACGAACGGCAACGACCGGTACAAGTGCACCGTGTGCAACAAAGCTTTCCGATCCTCCGAGTACCTGGTGCGCCATCGTCGGACGCACAGTGGTGAGCGGCCGTACCAGTGCGAGATTTGCGGCAAGAACTTCTCCACCATGAGCTACCTAGTGATCCACCGGCGTCGGCACACCTCCGAGCGGCCGTACAAGTGTACCTCCTGCGAGAAAGCGTTTGTCGACTCGCGTGCACTCCAGGAGCACGCCCGGCTACACACGGGCGATCGGGTGCGTTGTGAGATCTGCCAGAAAACGTACTCCAGCGTCAGCAACCTGATCGTGCACCGGCGCATCCACAGTGGCATTCATCCCTTCGAGTGTGACAGCTGTGGCAAATCGTTTGCGCAGAAAAATGCCCTCAAATATCACCTCAAGAAGCACGCCGAAACGCACAAGAAACAGGAGCAGCCAGAGCCCGTCGGTTAG
Protein Sequence
MKEATMIDAFDTADFNPELILSSVFLDPGLDFVTNIDDLSDNSIAADLLQQLGNSIFYPETSIATNISNGEIAGLAETIPQQQHAQHQQQQHHNHQHQQQQQQQQVLLQPSMVSTKGRDTIEKPTDEMRFETFGSDYAKSQLTAAVPLTIPMVQQQQQQQQSAVAVQQQQQQTCKCEFCEYLQANRISLTGDHSFQCEFCGEGFSTQTSFNRHRCGSTDIQIYRCENCRQEYGSSRAMSTIGNCEPRDKCDICNRNIVQSLPEEQAAYGPSMAAGSSPMSSQTTASVLSDGTIGGTVHLPTMIATLTSPEVSNESVSDLSANVNVRSIVNSPIEQHDLSSLDPFGSDSECLGQFFAAEPSSTSPCTASSTATNLQCQPMPTSANMGSLLSIPALHQPESAKTYFVLGNVDQLQQFHDIATPPPPATAEQAPVQQPPAGSNLPTAVTNSFHHLHLAPAGPGPHQQQQLLPLSLQNAAPATAGSLLLSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGISVMSLPPFGTGGLPRDADGSPLGRTLIPPPHGVGVQHHLQQHQQPLQQQQQHHHSSDVSLIHRDEEEEGKCDSSSSPLGLLVGSPSGIANGGGERRPHQAQSSTTTTTSTSTNPDRPYKCHICDRSYRNQKNLRSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCVTCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYRCELCGKTFPQYNNLKHHMKKHEQPSDAEQLLPQAMATSTGGPTPPSNGVSTTTSGSGTVLARISLSIQADTTGKGTVHMIASSTTGPASEYKCHICNKLYKSSDDLQEHLSQHSKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPEGADTRLPALPQNGAADVGQCAPSFGEDATTNGNDRYKCTVCNKAFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHAETHKKQEQPEPVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00105277;
90% Identity
iTF_00101094; iTF_00107118;
80% Identity
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