Basic Information

Insect: Anopheles coluzzii
Gene Symbol: Bcl11b
Assembly: GCA_016097175.1
Location: CM027930.1:2833512-2836790[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00014 0.0076 16.3 2.1 1 21 30 50 30 51 0.95

2 16 3.7e-07 1.9e-05 24.5 4.2 1 23 429 451 429 451 0.99

3 16 3.9e-07 2.1e-05 24.4 0.5 1 23 457 479 457 479 0.99

4 16 2.4e-05 0.0013 18.8 0.1 1 23 485 507 485 507 0.98

5 16 3.8e-05 0.002 18.2 0.6 2 23 513 534 512 534 0.96

6 16 3.3e-07 1.7e-05 24.6 4.0 1 23 540 562 540 562 0.99

7 16 3.7e-05 0.0019 18.2 2.5 1 23 632 654 632 654 0.97

8 16 6e-06 0.00031 20.7 2.5 2 23 661 682 660 682 0.98

9 16 1.9e-06 9.8e-05 22.3 0.8 1 23 688 710 688 710 0.98

10 16 2.4e-06 0.00012 22.0 0.1 2 23 716 737 715 737 0.98

11 16 1.8e-06 9.2e-05 22.4 2.1 1 23 743 765 743 765 0.99

12 16 1.8e-07 9.5e-06 25.5 2.1 1 23 813 835 813 835 0.99

13 16 3.3e-07 1.8e-05 24.6 0.9 1 23 841 863 841 863 0.99

14 16 4.7e-05 0.0024 17.9 0.3 1 23 869 891 869 891 0.98

15 16 4.4e-06 0.00023 21.1 0.3 2 23 897 918 896 918 0.97

16 16 3.1e-06 0.00016 21.6 1.2 1 23 924 946 924 946 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00014	0.0076	16.3	2.1	1	21	30	50	30	51	0.95
2	16	3.7e-07	1.9e-05	24.5	4.2	1	23	429	451	429	451	0.99
3	16	3.9e-07	2.1e-05	24.4	0.5	1	23	457	479	457	479	0.99
4	16	2.4e-05	0.0013	18.8	0.1	1	23	485	507	485	507	0.98
5	16	3.8e-05	0.002	18.2	0.6	2	23	513	534	512	534	0.96
6	16	3.3e-07	1.7e-05	24.6	4.0	1	23	540	562	540	562	0.99
7	16	3.7e-05	0.0019	18.2	2.5	1	23	632	654	632	654	0.97
8	16	6e-06	0.00031	20.7	2.5	2	23	661	682	660	682	0.98
9	16	1.9e-06	9.8e-05	22.3	0.8	1	23	688	710	688	710	0.98
10	16	2.4e-06	0.00012	22.0	0.1	2	23	716	737	715	737	0.98
11	16	1.8e-06	9.2e-05	22.4	2.1	1	23	743	765	743	765	0.99
12	16	1.8e-07	9.5e-06	25.5	2.1	1	23	813	835	813	835	0.99
13	16	3.3e-07	1.8e-05	24.6	0.9	1	23	841	863	841	863	0.99
14	16	4.7e-05	0.0024	17.9	0.3	1	23	869	891	869	891	0.98
15	16	4.4e-06	0.00023	21.1	0.3	2	23	897	918	896	918	0.97
16	16	3.1e-06	0.00016	21.6	1.2	1	23	924	946	924	946	0.98

Sequence Information

Coding Sequence: ATGCGCTTCGAAACATTCGGAAGCGATTACGCAAAGTCCCAGCTGACGGCGGCTGCCAACCGGATATCGCTGACCGGCGATCACTCCTTCCAGTGCGAGTTTTGCGGGGAGGGATTCTCCACCCAGACCAGCTTCAACCGGCATCGGTGCGGGAGTACAGACATCCAGATATACCGGTGCGAAAATTGCCGCCAGGAGTATGGTAGCTCGCGTGCCATGTCCACCATCGGTAACTGTGAGCCTAGGGACAAGTGTGATATCTGCAATCGCAACATTGTACAGTCGTTGCCAGAGGAGCAGGCGGCCTATGGCCCCTCGATGGCGGCTGGAAGCTCCCCAATGTCTTCACAAACCACAGCGTCCGTGCTGTCCGACGGCACGATTGGTGGAACGGTCCACTTGCCAACGATGATAGCGACGCTAACCTCCCCCGAAGTGTCTAACGAAAGCGTCAGCGATCTCAGTGCCAACGTCAATGTAAGGTCTATCGTGAACAGTCCCATCGAACAGCACGACCTAAGCAGCCTGGATCCGTTCGGGTCGGACAGCGAGTGTCTGGGTCAGTTCTTTGCCGCTGAGCCAAGCTCCACCTCGCCCTGTACGGCTAGCAGCACGGCAACCAACTTACAGTGTCAACCAATGCCAACTAGTGCCAACATGGGGAGTCTTCTCTCCATCCCTGTACTGCACCAGCCAGAGTCAGCGAAGACGTACTTCGTGCTTGGAAATGTGGATCAGTTGCAGCAATTTCACGACATAGCAGCACCACCACCACCAGCAACAGCAGAGCAAGCGCCAGTGCAGCAACCACCAGCCGGCAGCAATCTTCCAACAGCGGTCACCAATAGCTTCCATCATCTTCATTTAGCGCCAGCAGGACCTGGGCCTCATCAGCAGCAGCAACTGCTACCTCTCTCGCTGCAGAATGCCGCCCCCGCTACGGCCGGTTCGCTTCTGCTCAGCGAGCACGAGGTCACTAGTCTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAACCCTATGCCAAATCGCCCAACCAGGACCATGCCAAGACGGAGCTCCCAATCCAAGAGACGATCGTTGACACCAGCACCGGCATCAGTGTCATGTCGCTGCCACCGTTCGGAACTGGCGGACTGCCAAGGGACGCTGATGCGAACGGTGGCGGCGAAAGAAGGCCACATCAGGCACAGTCCTCCACTACTACCACCAGCACCAGCACCAGCACCAACCCCGATCGACCCTACAAGTGCCACATCTGCGACCGTTCGTACCGCAACCAGAAGAACCTGAGGTCCCATCTGAAGGTGCACGAGGGCATTCGGGCGTACCAGTGCGAGATCTGTGGCAAGAATTTCTCCGGCTCCAGCTATCTGGTGATCCACCGGCGGCGCCATACGGGCGAACGGCCATTCAAGTGCGTCACCTGCGGGAAGGCGTTCGTCGATTCGCGAGCGCTGGCCGTGCACGCGCGCTTGCACAGCGGCGAGCGGCTCAAGTGCGAAAAGTGCGAGAAAACTTTCTCCAGCGTGAGTGCCCTGACTGTGCACAATCGGCTGCACACCGGCATACACCCTTACCGGTGTGAGCTGTGTGGCAAAACATTCCCACAGTACAACAACCTGAAGCACCACATGAAGAAGCACGAGCAGCCGAGCGATGCAGAGCAGCTGCTGCCCCAAGCAATGGCGACCTCAACCGGTGGCCCCACACCACCGTCCAATGGGGTGAGCACTACGACGAGCGGCTCCGGCACTGTACTGGCGCGCATCAGTCTCTCGATACAGGCCGACACCACCGGCAAAGGAACGGTGCACATGATAGCCAGCTCGACCACGGGTCCGGCCTCCGAGTACAAATGCCACATCTGCAATAAGCTGTACAAATCCTCCGACGACCTGCAGGAGCACCTGAGCCAGCACAGCAAGGATCGGCCGAACCAGTGCGAGTTTTGCTCGAAAGTGTTTCCGCGCTCTTCGCACCTCATCATCCACCGGCGTCGGCACACGGGCGAGCGGCCCTTCAAGTGCAAATACTGCGACAAAGCGTTCGTTGACTCGCGCGCCCTCTCCGTCCACACGCGCCTGCACACGGGCGAGCGGGTCAAGTGCGAAATCTGCGAGAAAACGTTCGCCAGCTCGAGCGGTCTCATAGTGCACCGGCGCATCCACACCGGAGTGCATCCGTACAAGTGTGACTACTGCGAAAAGTCCTTCGCCCAATCGACGGCACTCAAGTACCATCTGAAAAAGCACGACACCGCCCTGCTGCCAACCACGACCACACCCGAGGCTGCTGATACGCGACTACCAGCCCTGCCCCAGGCCGGTGCCGCTGATGTTGGGCAATGTGCGCCCTCGTTTGGCGAGGACGCGACCACGAACGGCAACGACCGGTACAAGTGCACCGTGTGCAACAAAGCGTTCCGATCCTCCGAGTACCTGGTGCGCCATCGTCGGACGCACAGCGGTGAGCGGCCGTACCAGTGCGAGATTTGCGGCAAGAACTTCTCCACCATGAGCTACCTAGTGATCCACCGGCGTCGGCACACCTCGGAGCGGCCGTACAAGTGTACCTCCTGCGAGAAAGCGTTTGTCGACTCGCGTGCGCTCCAGGAGCACGCCCGGCTACACACGGGCGATCGGGTGCGTTGTGAGATCTGCCAGAAAACGTACTCCAGCGTCAGCAACCTGATCGTGCACCGGCGCATCCACAGTGGCATTCATCCCTTCGAGTGTGACAGCTGTGGCAAATCGTTTGCGCAGAAAAATGCCCTCAAATATCACCTCAAGAAGCACGCCGAAACGCACAAGAAACAGGAGCAGCCAGAGCCCGTCGGTTAG
Protein Sequence: MRFETFGSDYAKSQLTAAANRISLTGDHSFQCEFCGEGFSTQTSFNRHRCGSTDIQIYRCENCRQEYGSSRAMSTIGNCEPRDKCDICNRNIVQSLPEEQAAYGPSMAAGSSPMSSQTTASVLSDGTIGGTVHLPTMIATLTSPEVSNESVSDLSANVNVRSIVNSPIEQHDLSSLDPFGSDSECLGQFFAAEPSSTSPCTASSTATNLQCQPMPTSANMGSLLSIPVLHQPESAKTYFVLGNVDQLQQFHDIAAPPPPATAEQAPVQQPPAGSNLPTAVTNSFHHLHLAPAGPGPHQQQQLLPLSLQNAAPATAGSLLLSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGISVMSLPPFGTGGLPRDADANGGGERRPHQAQSSTTTTSTSTSTNPDRPYKCHICDRSYRNQKNLRSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCVTCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYRCELCGKTFPQYNNLKHHMKKHEQPSDAEQLLPQAMATSTGGPTPPSNGVSTTTSGSGTVLARISLSIQADTTGKGTVHMIASSTTGPASEYKCHICNKLYKSSDDLQEHLSQHSKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPEAADTRLPALPQAGAADVGQCAPSFGEDATTNGNDRYKCTVCNKAFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHAETHKKQEQPEPVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105277;
90% Identity: iTF_00104527;
80% Identity: -