Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: Bcl11b
Assembly: GCA_000349065.1
Location: KB665510.1:2098219-2119658[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00015 0.0073 16.2 2.1 1 21 71 91 71 92 0.95

2 16 3.8e-07 1.9e-05 24.3 4.2 1 23 537 559 537 559 0.99

3 16 4.1e-07 2e-05 24.2 0.5 1 23 565 587 565 587 0.99

4 16 2.5e-05 0.0012 18.6 0.1 1 23 593 615 593 615 0.98

5 16 3.9e-05 0.0019 18.0 0.6 2 23 621 642 620 642 0.96

6 16 3.4e-07 1.7e-05 24.5 4.0 1 23 648 670 648 670 0.99

7 16 3.8e-05 0.0019 18.0 2.5 1 23 740 762 740 762 0.97

8 16 6.2e-06 0.0003 20.5 2.5 2 23 769 790 768 790 0.98

9 16 1.9e-06 9.4e-05 22.1 0.8 1 23 796 818 796 818 0.98

10 16 2.4e-06 0.00012 21.8 0.1 2 23 824 845 823 845 0.98

11 16 1.8e-06 8.8e-05 22.2 2.1 1 23 851 873 851 873 0.99

12 16 1.9e-07 9.2e-06 25.3 2.1 1 23 921 943 921 943 0.99

13 16 3.5e-07 1.7e-05 24.5 0.9 1 23 949 971 949 971 0.99

14 16 4.8e-05 0.0023 17.7 0.3 1 23 977 999 977 999 0.98

15 16 4.5e-06 0.00022 21.0 0.3 2 23 1005 1026 1004 1026 0.97

16 16 3.2e-06 0.00015 21.4 1.2 1 23 1032 1054 1032 1054 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00015	0.0073	16.2	2.1	1	21	71	91	71	92	0.95
2	16	3.8e-07	1.9e-05	24.3	4.2	1	23	537	559	537	559	0.99
3	16	4.1e-07	2e-05	24.2	0.5	1	23	565	587	565	587	0.99
4	16	2.5e-05	0.0012	18.6	0.1	1	23	593	615	593	615	0.98
5	16	3.9e-05	0.0019	18.0	0.6	2	23	621	642	620	642	0.96
6	16	3.4e-07	1.7e-05	24.5	4.0	1	23	648	670	648	670	0.99
7	16	3.8e-05	0.0019	18.0	2.5	1	23	740	762	740	762	0.97
8	16	6.2e-06	0.0003	20.5	2.5	2	23	769	790	768	790	0.98
9	16	1.9e-06	9.4e-05	22.1	0.8	1	23	796	818	796	818	0.98
10	16	2.4e-06	0.00012	21.8	0.1	2	23	824	845	823	845	0.98
11	16	1.8e-06	8.8e-05	22.2	2.1	1	23	851	873	851	873	0.99
12	16	1.9e-07	9.2e-06	25.3	2.1	1	23	921	943	921	943	0.99
13	16	3.5e-07	1.7e-05	24.5	0.9	1	23	949	971	949	971	0.99
14	16	4.8e-05	0.0023	17.7	0.3	1	23	977	999	977	999	0.98
15	16	4.5e-06	0.00022	21.0	0.3	2	23	1005	1026	1004	1026	0.97
16	16	3.2e-06	0.00015	21.4	1.2	1	23	1032	1054	1032	1054	0.98

Sequence Information

Coding Sequence: ATGCGCTTCGAAACATTCGGAAGCGATTACGCAAAGTCCCAGCTGACGGCGGCTGTGCCACTCACTATCCCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACATGTAAATGTGAATTCTGCGAGTACCTTCAGGCCAACCGGATATCGCTGACCGGCGATCACTCCTTCCAGTGCGAGTTTTGCGGGGAGGGATTCTCCACCCAGACCAGCTTCAACAGGCATCGGTGCGGGAGTACAGACATCCAGATATACCGGTGCGAAAATTGCCGCCAGGAGTATGGTAGCTCGCGTGCCATGTCCACCATCGGTAACTGTGAGCCTAGGGACAAGTGTGATATCTGCAATCGCAACATTGTACAGTCGTTGCCAGAGGAGCAGGCGGCCTATGGCCCCTCCATGACGGCTGGAAGCTCCCCAATGTCTTCACAAACCACAGCGTCTGTGCTGTCCGACGGCACGATTGGTGGAACGGTTCACTTGCCAACGATGATAGCGACGCTAACCTCCCCCGAAGTGTCTAACGAAAGCGTCAGCGATCTCAGTGCCAACGTCAATGTAAGGTCTATCGTGAACAGTCCCATCGAACAGCACGACCTAAGCAGCCTGGATCCGTTCGGGTCGGACAGCGAGTGTCTGGGTCAGTTCTTTGCCGCTGAGCCAAGCTCCACCTCGCCCTGTACGGCTAGCAGCACGGCAACCAACTTACAGTGTCAACCAATGCCAACTAGTGCCAACATGGGGAGTCTTCTCTCCATCCCTGCACTGCACCAGCCAGAGTCAGCGAAGACGTACTTCGTGCTTGGAAATGTGGATCAGTTGCAGCAATTTCACGACATAGCACCACCACCACCACCAGCAACAGCAGAGCAAGCGCCAGTGCAGCAACCACCAGCCGGCGGCAATCTCCCTACAGCGGTCACCAATAGCTTCCATCATCTTCATTTAGCGCCAGCAGGACCTGGGCCTCATCAGCAGCAGCAACTGCTACCTCTCTCGCTGCAGAATGCTGCCCCCGCTACGGCCGGTTCGCTTCTGCTCAGCGAGCACGAGGTCACTAGTCTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAACCCTATGCCAAATCGCCCAACCAGGACCATGCCAAGACGGAGCTCCCAATCCAAGAGACGATCGTTGACACCAGCACCGGCATCAGTGTCATGTCGCTGCCACCGTTCGGAACTGGCGGACTGCCAAGGGACGCTGATGGTTCGCCGCTGGGCCGAACACTGATACCACCACCGCATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCGTCCGACGTGTCGCTGATACACCGGGACGAAGAAGAGGAAGGAAAATGTGATTCGTCATCTTCACCGCTTGGATTACTGGTCGGAAGCCCGCCTGGAATAGCAAACGGTGGCGGCGAAAGAAGGCCACATCAGGCACAGTCCTCCACTACCACCAGCACCAGCACCAACCCCGATCGACCCTACAAGTGCCACATCTGCGACCGTTCGTACCGCAACCAGAAGAACCTGAGGTCCCATCTGAAGGTGCACGAGGGCATTCGGGCGTACCAGTGCGAGATCTGTGGCAAGAATTTCTCCGGCTCCAGCTATCTGGTGATCCACCGGCGGCGCCATACGGGCGAACGGCCATTCAAGTGCGTCACCTGCGGGAAGGCGTTCGTCGATTCGCGAGCGCTGGCCGTGCACGCGCGCTTGCACAGCGGCGAACGGCTCAAGTGCGAAAAGTGCGAGAAAACTTTCTCCAGCGTGAGTGCCCTGACTGTGCACAATCGGCTGCACACCGGCATACACCCTTACCGGTGTGAGCTGTGTGGCAAAACATTCCCACAGTACAACAACCTGAAGCACCACATGAAGAAGCACGAGCAGCCGAGCGATGCAGAGCAGCTGCTGCCCCAAGCAATGGCGACCTCAACCGGTGGCCCCACACCACCGTCCAATGGGGTGAGCACTACGACGAGCGGCTCCGGCACTGTACTGGCGCGCATCAGCCTCTCGATACAGGCCGACACCACCGGCAAAGGAACGGTGCACATGATAGCCAGCTCGACCACTGGTCCGGCCTCCGAGTACAAATGCCACATCTGCAACAAGCTGTACAAATCCTCCGACGACCTGCAGGAGCACCTGAGCCAGCACAGCAAAGATCGGCCGAACCAGTGCGAGTTTTGCTCGAAAGTGTTTCCGCGCTCTTCGCATCTCATCATCCACCGGCGTCGGCACACGGGCGAGCGGCCCTTCAAGTGCAAATACTGCGACAAAGCGTTCGTTGACTCGCGCGCCCTCTCCGTCCACACGCGCCTGCACACGGGCGAGCGGGTCAAGTGCGAAATCTGCGAGAAAACGTTCGCCAGCTCGAGCGGTCTAATAGTGCACCGGCGCATCCACACCGGGGTGCATCCATACAAGTGTGACTACTGCGAAAAGTCCTTCGCTCAATCGACGGCACTCAAGTACCATCTGAAAAAGCACGACACCGCCCTGCTACCAACCACGACCACGCCCGAGGCTGCAGATACGCGGCTGCCAGCCCTGCCCCAGGCCGGTGCCGCCGATGTTGGGCAATGTGCGCCCTCGTTTGGCGAGGACGCGACCACGAGCGGCAACGACCGGTACAAGTGCACCGTGTGCAACAAAGCTTTCCGATCCTCCGAGTACCTGGTGCGCCATCGTCGGACGCACAGCGGTGAGCGGCCGTACCAGTGCGAAATTTGCGGCAAGAACTTCTCCACCATGAGCTACCTAGTGATCCACCGGCGTCGGCACACCTCGGAGCGGCCGTACAAGTGTACCTCCTGCGAGAAAGCGTTTGTCGACTCGCGTGCGCTCCAGGAACACGCCCGGCTACACACGGGCGATCGGGTGCGTTGTGAGATCTGCCAGAAAACGTACTCCAGCGTCAGCAACCTGATCGTGCACCGGCGCATCCACAGTGGCATTCATCCCTTCGAGTGTGACAGCTGTGGCAAATCGTTTGCGCAGAAAAATGCCCTCAAATATCACCTCAAGAAGCACGCCGAAACGCACAAGAAACAGGAGCAGCCAGAGCCCGTCGGTTAG
Protein Sequence: MRFETFGSDYAKSQLTAAVPLTIPXXXXXXXXXXXXXXXXXXXXXXXXTCKCEFCEYLQANRISLTGDHSFQCEFCGEGFSTQTSFNRHRCGSTDIQIYRCENCRQEYGSSRAMSTIGNCEPRDKCDICNRNIVQSLPEEQAAYGPSMTAGSSPMSSQTTASVLSDGTIGGTVHLPTMIATLTSPEVSNESVSDLSANVNVRSIVNSPIEQHDLSSLDPFGSDSECLGQFFAAEPSSTSPCTASSTATNLQCQPMPTSANMGSLLSIPALHQPESAKTYFVLGNVDQLQQFHDIAPPPPPATAEQAPVQQPPAGGNLPTAVTNSFHHLHLAPAGPGPHQQQQLLPLSLQNAAPATAGSLLLSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGISVMSLPPFGTGGLPRDADGSPLGRTLIPPPHXXXXXXXXXXXXXXXXXXXXXXXSSDVSLIHRDEEEEGKCDSSSSPLGLLVGSPPGIANGGGERRPHQAQSSTTTSTSTNPDRPYKCHICDRSYRNQKNLRSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCVTCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYRCELCGKTFPQYNNLKHHMKKHEQPSDAEQLLPQAMATSTGGPTPPSNGVSTTTSGSGTVLARISLSIQADTTGKGTVHMIASSTTGPASEYKCHICNKLYKSSDDLQEHLSQHSKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPEAADTRLPALPQAGAADVGQCAPSFGEDATTSGNDRYKCTVCNKAFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHAETHKKQEQPEPVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105277;
90% Identity: iTF_00093595;
80% Identity: -