Aste003283.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles stephensi
Gene Symbol
Bcl11b
Assembly
GCA_013141755.1
Location
CM023249.1:87801290-87827488[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.00018 0.011 16.0 2.1 1 21 203 223 203 224 0.95
2 17 10 5.8e+02 1.1 0.1 2 9 257 264 256 268 0.82
3 17 1.6e-06 9e-05 22.5 4.3 1 23 653 675 653 675 0.99
4 17 4.9e-07 2.8e-05 24.1 0.5 1 23 681 703 681 703 0.99
5 17 2.9e-05 0.0017 18.5 0.1 1 23 709 731 709 731 0.98
6 17 4.6e-05 0.0027 17.9 0.6 2 23 737 758 736 758 0.96
7 17 3.1e-07 1.8e-05 24.7 4.1 1 23 764 786 764 786 0.99
8 17 0.0002 0.011 15.9 1.1 1 23 853 875 853 875 0.95
9 17 7.4e-06 0.00042 20.4 2.5 2 23 882 903 881 903 0.98
10 17 2.3e-06 0.00013 22.0 0.8 1 23 909 931 909 931 0.98
11 17 2.9e-06 0.00017 21.7 0.1 2 23 937 958 936 958 0.98
12 17 2.2e-06 0.00012 22.1 2.1 1 23 964 986 964 986 0.99
13 17 4e-07 2.3e-05 24.4 2.3 1 23 1033 1055 1033 1055 0.99
14 17 4.1e-07 2.4e-05 24.3 0.9 1 23 1061 1083 1061 1083 0.99
15 17 5.7e-05 0.0033 17.6 0.3 1 23 1089 1111 1089 1111 0.98
16 17 5.4e-06 0.00031 20.8 0.3 2 23 1117 1138 1116 1138 0.97
17 17 3.8e-06 0.00022 21.3 1.2 1 23 1144 1166 1144 1166 0.98

Sequence Information

Coding Sequence
ATGAAAGAAGCCTCAATGATCGATGCATTCGATACAGCGGATTTTAATCCAGAACTGATCCTGTCCAGCGTGTTTCTGGACCACGGACTAGACTTTGTTACCAATATTGACGATCTGGGCGACAATATCATAGCGGCCGATCTGCTTCAGCAGTTGGGCAGTTCGGTGTTCTACACCGAAACGCCTCTCGCAACGAACATCAACAACGGTGCTGGACTCTGTGCCACCGGTACGCAGCAACATGcccaaaaccaacaacaacagcagcagcaacaacaacaacaacaaccacaacaacaacatcatcagcagcagattTTATCGCAACCACCCGCGCTACTATCGGCGAGAGCGCGTATGGCAATTGGTGAGAAACCCACCGACGAGATGCGCTACGACACGACGTTCGGAAGTGATTATGCAAAGCCTCAGCTTGTGCCGGCTGTGCCACTTACAATGCCGATGGCGCAACaaatgcaacagcaacaaccacagcaaacaacatcaatggctacgcagcagcagcagcaacagcagcagtcgtGCAAATGTGAATTCTGCGAGTATCTGCAAGCGAATCGGATATCTCTCACCGGCGATCACTCGTTTCAGTGCGAATTCTGCGGCGAAGGCTTCTCGAATCAGACCAGCTTCAACCGACATCGCTGTGGTGGGATGGACATACAGATATACCGGTGTGAAACCTGCCGGCAAGAGTATGGCAGCTCCAGAGCCGTCTCCAACATCGGTAACTGTGAGCCCAGAGATAAATGTGATATCTGTAATCGAACCATCGTACAGTCGTTGCCAGAGGAGCAGGCGGCTTATGGTCCCTCCTCGATGGTAGCGGGCAGTTCTGCGATAACTCCACAAACCACACCCGCGTCCATGTCGGATGGAACGATCGACGGGACGATTTCGATGCTGGTCACCTCTCCCGAAGTGTCAAACGAAAGCGTCAGTGATCTGAGCGCTAATGTGCGGTCGATAGTGAACAGTCCCATCGAACAGCACGATCTAAGCAGCATCGATCCATTCGGGTCGGACAGTGAGTGTTTGGGGCAGTTCTTTGCAACGGAGGCAACGTCCACCTCACCCTGTACGGCTAGCACTACCGGTAGCATACAGTGCACACCAATGCCGACGAGTGCCAACATCGGAAGCCTTCTTCCGACCACTGCGCTTCACCAACCAGAGTCCGCGAAAACGTACTTTGTGCTGGGGAACGTGGATCAATTGCAACAGTTccatgcagcagcggcagcagcagcagcagcaacatcagccgtgcagcagcaacccAGCAACAATCTTCCAACGGTCACCAACAATAGCTTCCATCCGCTTCATCTGCCACCGCCGGGACCAGGGcctcatcagcagcagcagcaacagctaccTTTCTCACTGCAGAACGTGGCGCCGGTCACCGCCGGGTCACATCTGCCCAGTGAGCACGAGGTCACTAGTCTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAACCCTATGCCAAATCGCCCAACCAGGACCACGCCAAGACGGAGCTCCCGATACAGGAGACAATCGTCGACACTAGcaccggcggcagcagcactgTCATCCCGCTCCAGCAGTTCGGTTGTGGCGGATTGCCAAGGGATGATGCTGCTCTCGGTCGCGCGCTGATGACGCACGGCGTTGCACAGCACATGCACGTTCAACCACAATCACAGCCACAGCCACAACATCACCACCCGTCTAATCTAGCACAAACCAAGACACACCTGGATGACGATGAGGAAGGAAAATGTGATTCGTCATCTCCATCGCTCGGCATATTTGTCGGTGGTTCCACCGGAATGGCGAATGGCGAAGACAAAGGGACGCAGAAACCCCAATCCTCCCTTGCCAACGGTTCCAACCTGGAACGGCCCTACAAGTGTCACATCTGCGAACGTTCGTACCGGAATCAGAAGAACCTGAAGTCACATCTGAAGGTACACGAGGGCATCCGCGCGTATCAATGTGAAATTTGTGGTAAGAATTTCTCCGGCTCCAGCTACCTGGTGATCCACCGACGGCGCCACACGGGTGAGCGGCCATTCAAATGTGTCACGTGCGGGAAGGCGTTCGTTGATTCGCGAGCACTAGCCGTGCACGCGCGTTTGCATAGCGGCGAACGGCTCAAGTGCGAAAAGTGTGAGAAAACTTTCTCCAGCGTGAGTGCCCTCACGGTGCACAACCGGCTGCACACCGGCATCCATCCCTACAAATGTGAACTGTGTGGCAAAACCTTTCCACAGTACAACAACCTGAAACACCACATGAAAAAACACGAGCAACCGAATGCCGCGGAAAATCGATCGCCCGTTAGCACTCCGCCGACCTGTGGCCCAGCGATGTCCAACGGAGTCAGCACCACGAGCGGTTCCGGCCTCGCTTCGGGACGGTTGGGTCCGACGCTGCCGGCCGACGCGAACCCGAACGGAGCGGCACATATGGTGGCCAGCTCGACTACCGGGCCTCCGTTCGAGTACAAATGTCACATCTGCAGCAAACTGTACAAATCCGCCGACGACCTGCAGGAGCACCTCGGCCAGCACAGCAAGGATCGACCGAATCAGTGCGAGTTCTGCTCGAAGGTGTTTCCGCGCTCGTCGCACCTCATCATCCACCGACGGCGACACACGGGCGAGCGACCCTTCAAGTGCAAATACTGTGACAAAGCGTTCGTCGACTCGCGAGCCCTGTCCGTCCACACGCGTCTGCACACGGGCGAACGGGTAAAGTGCGAGATCTGCGAGAAAACGTTCGCCAGCTCCAGCGGGCTCATAGTGCACCGGCGCATACACACCGGCGTGCATCCGTACAAGTGCGACTACTGCGAAAAATCGTTCGCCCAATCGACGGCACTCAAGTACCACCTGAAGAAGCACGATACGGCCCTGCTGCCCACGACGACCACGCCGGAAAGTGCCGAGTCACGGCTTTCCACGCTACCACAGCACGGTGCGGCCGATCTAGGTCAGTGTCCACCGTTCGGAGACGACTCGACGGCGAACGGGAACGATCGGTACAAGTGCACCGTGTGCAGCAAGGTGTTCCGATCCTCCGAGTACCTGGTGCGTCACCGACGAACGCACAGCGGCGAGCGGCCGTACCAGTGCGAGATTTGCGGCAAAAACTTCTCCACCATGAGCTACCTTGTGATCCACCGGCGTCGGCACACGTCCGAGCGACCGTACAAGTGTACGTCCTGCGAGAAGGCCTTCGTCGATTCGCGTGCCCTGCAGGAGCACGCCCGGCTACACACTGGCGATCGTGTGCGGTGCGAGATCTGCCAAAAAACCTACTCCAGCGTAAGCAATCTGATCGTCCACCGACGCATCCACAGCGGAATCCATCCGTTCGAGTGCGACAGCTGTGGCAAATCGTTTGCCCAAAAAAATGCCCTCAAGTACCACCTCAAGAAACACAACAAGCAGGATCAAACAGAGCCGATGGGCTAG
Protein Sequence
MKEASMIDAFDTADFNPELILSSVFLDHGLDFVTNIDDLGDNIIAADLLQQLGSSVFYTETPLATNINNGAGLCATGTQQHAQNQQQQQQQQQQQQPQQQHHQQQILSQPPALLSARARMAIGEKPTDEMRYDTTFGSDYAKPQLVPAVPLTMPMAQQMQQQQPQQTTSMATQQQQQQQQSCKCEFCEYLQANRISLTGDHSFQCEFCGEGFSNQTSFNRHRCGGMDIQIYRCETCRQEYGSSRAVSNIGNCEPRDKCDICNRTIVQSLPEEQAAYGPSSMVAGSSAITPQTTPASMSDGTIDGTISMLVTSPEVSNESVSDLSANVRSIVNSPIEQHDLSSIDPFGSDSECLGQFFATEATSTSPCTASTTGSIQCTPMPTSANIGSLLPTTALHQPESAKTYFVLGNVDQLQQFHAAAAAAAAATSAVQQQPSNNLPTVTNNSFHPLHLPPPGPGPHQQQQQQLPFSLQNVAPVTAGSHLPSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGGSSTVIPLQQFGCGGLPRDDAALGRALMTHGVAQHMHVQPQSQPQPQHHHPSNLAQTKTHLDDDEEGKCDSSSPSLGIFVGGSTGMANGEDKGTQKPQSSLANGSNLERPYKCHICERSYRNQKNLKSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCVTCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYKCELCGKTFPQYNNLKHHMKKHEQPNAAENRSPVSTPPTCGPAMSNGVSTTSGSGLASGRLGPTLPADANPNGAAHMVASSTTGPPFEYKCHICSKLYKSADDLQEHLGQHSKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPESAESRLSTLPQHGAADLGQCPPFGDDSTANGNDRYKCTVCSKVFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHNKQDQTEPMG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00105277;
90% Identity
-
80% Identity
-