Basic Information

Gene Symbol
-
Assembly
GCA_017607455.1
Location
JAANHZ010000874.1:864685-871049[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.22 11 5.8 7.5 2 23 199 221 198 221 0.97
2 18 0.027 1.4 8.6 2.2 1 23 270 292 270 292 0.97
3 18 0.81 41 4.0 1.1 1 23 341 363 341 363 0.97
4 18 0.036 1.8 8.2 0.1 1 20 411 430 411 432 0.92
5 18 0.0008 0.041 13.4 1.8 1 23 472 494 472 494 0.98
6 18 2.6e-05 0.0013 18.1 0.1 1 23 541 563 541 563 0.96
7 18 0.0025 0.13 11.9 0.1 1 23 569 591 569 591 0.97
8 18 1.4e-05 0.00071 18.9 0.2 1 23 634 657 634 657 0.96
9 18 0.002 0.1 12.1 0.6 1 23 663 686 663 686 0.96
10 18 2.9e-05 0.0015 18.0 2.5 2 23 694 716 693 716 0.97
11 18 0.00011 0.0054 16.2 0.0 1 23 722 744 722 744 0.93
12 18 0.058 2.9 7.6 0.1 1 20 795 814 795 814 0.97
13 18 0.11 5.3 6.7 0.4 2 23 834 855 833 855 0.96
14 18 6.8e-06 0.00034 19.9 2.3 1 23 868 890 868 890 0.97
15 18 8.4e-05 0.0043 16.5 3.1 1 23 912 935 912 935 0.94
16 18 0.0015 0.074 12.6 1.3 2 23 994 1016 993 1016 0.95
17 18 0.00035 0.018 14.6 1.6 1 23 1034 1057 1034 1057 0.93
18 18 0.0034 0.17 11.4 0.3 2 23 1150 1172 1150 1172 0.96

Sequence Information

Coding Sequence
ATGGATATAGATTACGAAAATAGTGTAGAAATTATCGAGGAGACTGTCAATAATATAGAAGTTATGAAGGAGACAGCCAATAATGTAGAAGTAATCGAGAAGACTACCAATAATGTAGAAGTTGTCGAGAAGATCATCAATGATGTAGAAATTATTGAGAAGATCCCCACTAACTTGAAAAAACcaCATCCAGTTCAATCAGTGGAAAACAATGAAgctaataatgaaaaagtgcAAGATGTAGTAGATAACAGCGATGTTAATGATACTGCGAATGATACTAACAAAGACCCCGAATCAATCTCGTCTGCAATGGAAAAGGAAACTGATAAGGAAAAGAATCAAGCGGATCAGCAGGATTCTATAGTTCTGTGTTCGATTAAAAGCGAGCCACAAGATGAAGATGATACCGATGGTACCATAGAAATAGAATCGAATAGCAGTGAATTGAATGCCATGGCAGTCGATGAGACAGAGGACACTATCATGGAGGCTGATTCCACGCAAAAGTCTAATGCGGCTGGCGCATCGCCTAAGAAGAAATTCAGACGCGGTCCTCATACTCACTTCAGAGGAACGCGTGTTTTTAAGCAGAAGTGCACGCACTGCCAGATATTTTTGCATTCTAAATACTCGTACATGAAACATATGAAGAGATTTCACAGTAAGGAAAATGGCATTGGAAATTCAGAGATGCGGAACGACGACGAGGAGATGATAGAGGATCTAGAAGATGAATTGATCAGTATGGAGAAGGACTCGCCGCTGACGCAAGTTCAACAGGACATTATTAGTCAACTGAAAACTTTTTCTTGCTACTCTTGCGAGCAGACATTTAATGATCGACGCAGCACTCTTTCTCATATACGTCAACATATGCCGGATCTAAGACCATACACATGTATTGCTTGTTTGACAGAATTTCCAGATCGATCAATGTATCAGTTGCATTGCGGAGCTTCCTTCGAATGCGCCATGAAGATTGCCCTAGTTGTACCGAAACACGGTAGCGAGCGATATTTTACATGTAACATGTGTTTGCGTTCAATGCAAGGTAGAAAGGAGTTACTCAGTCATTTGTCGAAGCATTCTGATAAGCAGTACGAGGAGATGATGTCATCGTCAACGCGAGCCCCGCCTAAACTGAAGCCGATGGCACCGTTGCCATCCTCGAAAAACAGCACTCTGCATAAGAACGGACCTTATAAGAATGGTGATCCAAAGCATAATCATGCCTGCGATCTATGCGGCATGATCTATCGATATCGGCCCAATATGCTCAAGCACAGAGAGGTATGTGCGCGATTGGACCCAGACAACAGAATATTGTACAAATGCGTGCATTGTTACATGACGTTTCTTGTGTTTAAGAAGTTCCATTATCATATTACAGCCGatcataagaaaaaagattttacttgTTCTGAGTGTTTTTCCAAATTCCGATCACCCAGCGATTTTGTAACTCATTACGAAACCCATCGCACGACAATGCAAGATAACCAACAAGAGCAGTATGACAGTACCTCGCAGAATACAGTTCAAACACCATTGAAGGAACGTAATGCTTACGAAACAAATGTCAAATCAAGAGTTAGTTCACGAATATCAAATCAGCAGTATCCTTGTCCTCTCTGTCCCGAGAAGTTCTCCACGAAGGTTGAACTGAACGAGCATCGGACTCTTCATCTCAAAATGAAGATATATTCGTGCGCCATTTGCCGTAGCTTATTCAGCAGCGCCGGCTCCTTGGAGATCCATATGAAGGATCATGGTATCGAAGACGCGCATGAAAGGGACGCCAATGTATCTTGTGTAGAATTCGGCAGCTTGGATGAAGATGTGAGGATTGAGAAAGATTTGGTGAACATCAGTAGCATCTCGGATCCTGGTCAAAATCATGAATGTGGCGAATGTGGTAAGGTACTATCCAGTTACGCTAATCTTCGACGACACGCTAAAATTGCTCACCGAAACACTAAGATCTATGATTGTGTCGATTGCTCGCGAATGTTTATGCGTAAAGATTTGTACGATACTCATATGGAGATCAAGCATAATTCTAAGAACACAATGCTGCAGTGTCCGCAATGTCCCAAGAGTTTTGTCTTCCATTCGAATTTCACTTATCACTTCCGTACTGCTCACAAATCACAAAGCAGTTATGCCTGCGATATCTGCGGCAAAGTCTTTGTTGAGGAAGCGTCTTTGAAAATACATAGGGGCTGGCACAATCGCGCCAATTCACGTTTGAGCACTCGATTTATACTTGGAGATCAAAATACATCTAATGACGCGCAAAAGGAATCAAGTAGCGTTGAATCTGTTGAGAATTCAGAACGGCCGGCGAGAGCACGAACACTAACAAAGACATCAGGGAATTACCAATGTCAAGTATGCAATGACAAATTCAATGATGTCGTAGAACTAAGAACCCATTTGTGGGACGTCCACTGCGCTCGCAACAAACCAGAGAAGAGTTTCTCTAATGATGAACTTCAATGCGAACTCTGCACGAACATTTTCCCCGATAAGGGAACCCTAGCATGTCATATGCAATGGCACAAGGCTAATCCTATTCTCAGTGACATACAAAAAACGTTCTTCTGCGAAATATGCGGCAGATCTTACAGATCGAAGAAGACTCTATGGAAGCACAAGAGACTTCACAAAGCTACCGCTGTAGCATCAATTAAATTCCAATCTTTGGCTAGAAAACCGATGGCTACACAATTCCTGTGCAACTTCTGTCGCAAAGTTTTTTCAAGCAATCAATCTTTGCAACGGCATAAACTCACTTTCCACAGTGATCCGCTGAATCAACAACGTGCGCAGCAACAGTTATGCAACAGCAGTCAATTATCGTCATTTGATGAACCAAGAACAAAGCGCATGAAACCagacattgaaaatgataattcGCAGACTAAATTGTCGCCTTTCGCCATGGACTTCGCTGGCGAGAGAAGGAAACCGGTCATGTGCCATGTTTGCAAGAAAATGTTCCCTAACATGAGCGTGCTGTACAAGCATAAGCAAATGGTTCACAAACGATCAAGAATACCCGAGTGTATACCGATGTCGACTCAGGATGGCAAATTTTCATGCAATATCTGCTTCAAGAAATTCCCCGGTCTATCAAATCTGCGAcaacattttacaattaaacacAAGAAAACGTCCGAATCCAGCAACGCATCAATAGCAGCGAGTAATGAGAGATTGTCGCTTTCGACACCCGAACGTCCAAAGGAGGGAACCTATGAAGTGGCCTACAATAACGTGATGTACAGCTGTAAATTGTGCAAGCAGTGTCATGTTTTCAATAAGGATTCTATCATACGCCATATCACCAATGTGCACAACGCAGTGTATCAGGCCGATAGCAAGACGTTCCATAGGGAAGTCACTCTGAGCACTTACGTAGTAAAGGACGCGATCGGAGCTACTTGTCCGCGATGCGATGTTAAATATCCTAATAACAGGGCTCTGAAGATACACTATATTAAGTTCCacgaaaataatgat
Protein Sequence
MDIDYENSVEIIEETVNNIEVMKETANNVEVIEKTTNNVEVVEKIINDVEIIEKIPTNLKKPHPVQSVENNEANNEKVQDVVDNSDVNDTANDTNKDPESISSAMEKETDKEKNQADQQDSIVLCSIKSEPQDEDDTDGTIEIESNSSELNAMAVDETEDTIMEADSTQKSNAAGASPKKKFRRGPHTHFRGTRVFKQKCTHCQIFLHSKYSYMKHMKRFHSKENGIGNSEMRNDDEEMIEDLEDELISMEKDSPLTQVQQDIISQLKTFSCYSCEQTFNDRRSTLSHIRQHMPDLRPYTCIACLTEFPDRSMYQLHCGASFECAMKIALVVPKHGSERYFTCNMCLRSMQGRKELLSHLSKHSDKQYEEMMSSSTRAPPKLKPMAPLPSSKNSTLHKNGPYKNGDPKHNHACDLCGMIYRYRPNMLKHREVCARLDPDNRILYKCVHCYMTFLVFKKFHYHITADHKKKDFTCSECFSKFRSPSDFVTHYETHRTTMQDNQQEQYDSTSQNTVQTPLKERNAYETNVKSRVSSRISNQQYPCPLCPEKFSTKVELNEHRTLHLKMKIYSCAICRSLFSSAGSLEIHMKDHGIEDAHERDANVSCVEFGSLDEDVRIEKDLVNISSISDPGQNHECGECGKVLSSYANLRRHAKIAHRNTKIYDCVDCSRMFMRKDLYDTHMEIKHNSKNTMLQCPQCPKSFVFHSNFTYHFRTAHKSQSSYACDICGKVFVEEASLKIHRGWHNRANSRLSTRFILGDQNTSNDAQKESSSVESVENSERPARARTLTKTSGNYQCQVCNDKFNDVVELRTHLWDVHCARNKPEKSFSNDELQCELCTNIFPDKGTLACHMQWHKANPILSDIQKTFFCEICGRSYRSKKTLWKHKRLHKATAVASIKFQSLARKPMATQFLCNFCRKVFSSNQSLQRHKLTFHSDPLNQQRAQQQLCNSSQLSSFDEPRTKRMKPDIENDNSQTKLSPFAMDFAGERRKPVMCHVCKKMFPNMSVLYKHKQMVHKRSRIPECIPMSTQDGKFSCNICFKKFPGLSNLRQHFTIKHKKTSESSNASIAASNERLSLSTPERPKEGTYEVAYNNVMYSCKLCKQCHVFNKDSIIRHITNVHNAVYQADSKTFHREVTLSTYVVKDAIGATCPRCDVKYPNNRALKIHYIKFHENND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2