Basic Information

Gene Symbol
-
Assembly
GCA_001594055.1
Location
NW:453177-460932[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 4.4 2.9e+02 1.5 0.1 2 17 89 104 88 105 0.88
2 19 0.23 15 5.6 7.5 2 23 331 353 330 353 0.97
3 19 0.028 1.9 8.4 2.2 1 23 402 424 402 424 0.97
4 19 0.85 56 3.8 1.1 1 23 473 495 473 495 0.97
5 19 0.039 2.5 8.0 0.1 1 20 543 562 543 564 0.92
6 19 0.0014 0.094 12.5 1.2 1 23 604 626 604 626 0.98
7 19 1.7e-05 0.0011 18.6 0.1 1 23 673 695 673 695 0.96
8 19 0.0033 0.22 11.4 0.1 1 23 701 723 701 723 0.97
9 19 1.5e-05 0.00096 18.8 0.2 1 23 766 789 766 789 0.96
10 19 0.0017 0.11 12.3 0.5 1 23 795 818 795 818 0.96
11 19 0.0011 0.072 12.9 4.3 2 23 826 848 825 849 0.96
12 19 0.00011 0.0073 16.0 0.0 1 23 857 879 857 879 0.93
13 19 0.11 7 6.6 0.1 1 20 939 958 939 958 0.96
14 19 0.055 3.6 7.5 0.9 2 23 978 999 977 999 0.96
15 19 1.4e-06 8.9e-05 22.0 1.0 1 23 1012 1034 1012 1034 0.98
16 19 8.8e-05 0.0058 16.3 3.1 1 23 1056 1079 1056 1079 0.94
17 19 0.021 1.4 8.8 1.9 2 23 1138 1160 1137 1160 0.95
18 19 0.00037 0.024 14.4 1.6 1 23 1178 1201 1178 1201 0.93
19 19 0.0036 0.24 11.3 0.3 2 23 1293 1315 1293 1315 0.96

Sequence Information

Coding Sequence
ATGGACGAGAATGTAGTGGAGATCGAAAACGAGAAGGAGATCGAGAACGAGGAGGAGATCGAAAACGAGGAGGAGATCGAAAATGAGGAGGAGATCGAGAACGTGGAGAATGTCTGCAGACTGTGCCTTTCCACGGATGGACCTAAATCTTCGGTGTTTCTAACGGAGGAGGAAAAAAAGGAATCGTCCAACGTGCCGCTGGTTGCTAAAATTCAGGCCTGCCTGTCGATCCAGatttcgaCAGCCGATAAGCTATCTACATGGATATGCacaaattgtgtaaaaagCGTTAATCAATGGTATACCTACAAGGAATCGTGTTTGCGCTCCCAAGACAAACTACAAGAATGGCTGGTAAATCAATTGCAGTCAAATTCTACGATTATCAGGATCAAAGATGAACCAATGGACATAGATTACGAAGATAGTGTAGAAATTATCGAGGAGGTCGTCAATAATGTAGATGTTATCGAGGGGACCGCTAATAATGTAGAAGAAATCGAGAAGACCAccaataatatagaaattgttGAGAAGACCACCAATGATGTAGAAATTATCGAGGAGACCTCCACTAACTTGGAACAACcaCATCCACCAGCTCAAACAGTGGAAAACAGTGAATCTAGTAATGGAAAAGTGCAAGATGTAGTAGATGACAGCGATGCTAATGATACTAACAAAGATCCCGAATCAATCTCGTCCGCAATGGAAAAGGAAACTAATAAGGAAAGAACTCAAACGGATCAGCAGGATTCTGTAGTTCTGTGTTCCATTAAAAGCGAACCGCAAGATGAAGATGATACCGATGGTACCATAGAAGTAGAATCGACTAGCAGTGAATTGAATGCCATGGTAATCGATGAGGCAGAGGACACTGTCATGGAGGCTGATTCCACGCAAAAGTCTAATGCGGGTGGCGTATTgcctaaaaagaaatttagacGCGGTCCTCATACTCACTTCAGAGGAACGCGTGTTTTTAAGCAGAAATGCACGCACTGCCAGATATTTTTGCATTCTAAATACTCGTACATGAAACACATGAAGAGGTTCCACAGTAAAGAAAATGGCATTGGAAATTCAGAGATACGGAACGACGACGAGGAGATGGTAGAGGATCTAGAAGATGAATTGATCAGTATGGAGAAGGACTCACCGCTGACGCAAGTTCAACAGGACATTATTAGTCAActgaaaactttttcttgCTACTCTTGCGAGCAGACGTTTAACGATCGACGTAGCACTCTTTCTCATATACGTCAACATATGCCGGATCTAAGACCATACACATGTATTGCTTGTTTGACAGAATTTCCAGATCGATCGATGTATCAATTACATTGCGGAGCTTCCTTCGAATGCGCCATGAAGATTGCCCTAGTTGTACCGAAACATGGTAGCGAGcgatattttacatgtaacatGTGCTTGCGTTCAATGCAAGGTAGAAAGGAGTTACTCAGCCACTTGTCGAAGCATTCTGATAAGCAGTACGAGGAGATTATGTCATCGTCGACACGATCCCCGCCTAAATTGAAACCGATGGCACCGTTGCCATCCTCGAAAAACAGCACTCTCCATAAGAGCGGACCTTACAAGAATGGCGATCCAAAGCATAATCATGCCTGCGATCTATGCGGCATGATTTACCGATATCGGCCCAATATGCTCAAGCACAGGGAGATATGTGCGCGATTGGATCCAGACAacagaatattatacaaatgcgTGCATTGTTACATGACGTTCCTTGTGTTTAAGAAGTTccattatcacattacagccgatcataagaaaaaagattttacttGTTCTGAGTGCTTGTCCAAATTTCGATCACCCAGTGATTTTGTAACTCATTACGAAACCCATCGCACGACAATGCAAGACAATCGGCAAGTGCAGTATGACAGTACCTCGCAGAATACAAGTCAAACGCCATTGAAGGAACGTAATGCTTACGAAACAAATGTTAAATCAAGAGTTAGTTCACGAATATCAAATCAGCAGTATCCTTGCCCTCTCTGTCCCGAGAAGTTTTCCACGAAGGCTGAACTGAACGAGCATCGGACTCTTCATCTCAAAATGAAGATATATTCGTGCGTCATTTGCCGTAGCTTATTCAGCAGCGCCGGCTCCTTGGAGATCCATATGAAAGATCATGGTATCGAAGACGCGCACGAAAGGGACGCCAATGTCTCTTGCGTGGAATTAGGCAGCTTGGACGAGGATGTGAGGATTGAGAAAGATTTGGTGAATATCAGTACCATCTCGGATCCTGGTCAAAATCATGAATGTGGCGAATGTGGTAAGGTACTATCCAGTTACGCTAATCTTCGACGACACGCTAAAATCGCTCACCGGAACACTAAGATCTATGATTGTGCCGATTGCTCGCGAATGTTTATGCGTAAAGATTTGTACGATACTCATATGGAAATCAAGCACAATTCTAACAAGACAATGCTGCAGTGTCCGCAATGCCCGAAGAGTTTTGTCTTCCATACGAATTTCTCTTATCACTTCCGTACTGCTCATCACAATCAGAAATCACAAACTGGTTATGCTTGCGATATCTGCGGCAAAGTCTTTGTTGAGGAAGCGTCTTTGAAAATACATAGGGGCTGGCACAATCGCGCCAATTCACGTTTGAACACTCGATTTATATTGGGAGATCAGAATGCGTCCAATGATGCGCAAAAAGAATCAAGTAGCGTTGAATCTGTTGAGAATTCAGAACGGCCGGCAAGAGCACGAAAGTCCTTCCCTAATCCACCACTTCAATCACTAACAAAGATATCAGGGAATTACCAATGTCAAGTATGCAATGATAAATTCAATGATGTCATAGAACTGAGGACCCATTTGTGGGACGTCCACTGCGCTCGCAACAAACCAGAGAAGAGTTTCTCTAATGATGAGCTTCAATGCGAACTCTGCACGAACATTTTCCCCGATAAGGAAACCCTAACATGTCATATGCAATGGCACAAGGCTAATCCTATTCTCAGTGACATACAAAAGACGTTCTCCTGCGATATATGCGGCAGATCTTATAGTTCGAAGAAGGCTCTATGGAAGCACAAAAGGCTTCACAAAGCTACCGCTGTAGCATCAATTAAATTCCAATCTTTGGCTAGAAAACCGATGGCTACACAATTTCTGTGCAACTTCTGTCGCAAAGTTTTTTCAAGCAATCAGTCTTTGCAACGGCACAAACTCACTTTCCACAGTGATCCGCTGAATCAACAACGTTCGCAGCAACAGTTGTACAACAGCAGTCAATTACCGTCATTTGATGAACCAAGGGCAAAGCGCATGAAACTAgacattgaaaatgataattCGCAGACTAAATTGTCGCCTTTCGCTATGGACTTCGCTGGTGAGAGAAGGAAGCCGGTCATGTGCCATGTTTGCAAGAAAATGTTCCCTAACATGAGCATACTGTACAAGCATAAGCAAATGACCCACAAACGACCAAAAATACCCGAGTGTATACCGATGTCGACTCAGGATGGCAAATTTTCATGCAACATCTGTTTCAAGAAATTCCCTGGTCTATCAAATCTGCGACAACATTTTACAATCAAACACAAGAAGACGTCCGAAGCCAGCAACGCATCAATGGCAGTGAGCAATGAGAGATTGTCGCTTCCGACACCCGAACGTCCAAAGGAGGGAACCTATGAAGTGGCCAATAACGTAATGTACAGCTGTAAATTATGCAAGCAGTGTCACGTCTTCACTAAGGAGTCCATCATAAGCCATATCACCAATGTGCACAATGCAGTGTATCAGGCCGATAGCAAGACGTTCCACAGGGAGGTCACTCTGAGCACTTACGTAGTAAAGGACGCGATCGGAGCTACTTGTCCGCGATGCGATGTTAAATATCCTAATAACAGGGCTCTGAAGATACACTATATTAAGTTCCACGAAAATAacgattaa
Protein Sequence
MDENVVEIENEKEIENEEEIENEEEIENEEEIENVENVCRLCLSTDGPKSSVFLTEEEKKESSNVPLVAKIQACLSIQISTADKLSTWICTNCVKSVNQWYTYKESCLRSQDKLQEWLVNQLQSNSTIIRIKDEPMDIDYEDSVEIIEEVVNNVDVIEGTANNVEEIEKTTNNIEIVEKTTNDVEIIEETSTNLEQPHPPAQTVENSESSNGKVQDVVDDSDANDTNKDPESISSAMEKETNKERTQTDQQDSVVLCSIKSEPQDEDDTDGTIEVESTSSELNAMVIDEAEDTVMEADSTQKSNAGGVLPKKKFRRGPHTHFRGTRVFKQKCTHCQIFLHSKYSYMKHMKRFHSKENGIGNSEIRNDDEEMVEDLEDELISMEKDSPLTQVQQDIISQLKTFSCYSCEQTFNDRRSTLSHIRQHMPDLRPYTCIACLTEFPDRSMYQLHCGASFECAMKIALVVPKHGSERYFTCNMCLRSMQGRKELLSHLSKHSDKQYEEIMSSSTRSPPKLKPMAPLPSSKNSTLHKSGPYKNGDPKHNHACDLCGMIYRYRPNMLKHREICARLDPDNRILYKCVHCYMTFLVFKKFHYHITADHKKKDFTCSECLSKFRSPSDFVTHYETHRTTMQDNRQVQYDSTSQNTSQTPLKERNAYETNVKSRVSSRISNQQYPCPLCPEKFSTKAELNEHRTLHLKMKIYSCVICRSLFSSAGSLEIHMKDHGIEDAHERDANVSCVELGSLDEDVRIEKDLVNISTISDPGQNHECGECGKVLSSYANLRRHAKIAHRNTKIYDCADCSRMFMRKDLYDTHMEIKHNSNKTMLQCPQCPKSFVFHTNFSYHFRTAHHNQKSQTGYACDICGKVFVEEASLKIHRGWHNRANSRLNTRFILGDQNASNDAQKESSSVESVENSERPARARKSFPNPPLQSLTKISGNYQCQVCNDKFNDVIELRTHLWDVHCARNKPEKSFSNDELQCELCTNIFPDKETLTCHMQWHKANPILSDIQKTFSCDICGRSYSSKKALWKHKRLHKATAVASIKFQSLARKPMATQFLCNFCRKVFSSNQSLQRHKLTFHSDPLNQQRSQQQLYNSSQLPSFDEPRAKRMKLDIENDNSQTKLSPFAMDFAGERRKPVMCHVCKKMFPNMSILYKHKQMTHKRPKIPECIPMSTQDGKFSCNICFKKFPGLSNLRQHFTIKHKKTSEASNASMAVSNERLSLPTPERPKEGTYEVANNVMYSCKLCKQCHVFTKESIISHITNVHNAVYQADSKTFHREVTLSTYVVKDAIGATCPRCDVKYPNNRALKIHYIKFHENND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00182140;
90% Identity
iTF_00016844;
80% Identity
-