Waur004208.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Wasmannia auropunctata
Gene Symbol
prdm10
Assembly
GCA_000956235.1
Location
NW:106980-113714[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00022 0.016 15.1 0.1 2 23 528 549 527 549 0.96
2 11 0.004 0.29 11.1 1.3 3 23 562 582 561 582 0.96
3 11 0.012 0.85 9.7 3.3 1 19 599 617 599 621 0.93
4 11 0.00025 0.018 14.9 0.3 2 23 630 651 629 651 0.97
5 11 0.003 0.22 11.5 0.3 1 23 658 680 658 680 0.98
6 11 0.00058 0.043 13.7 4.2 1 23 687 709 687 710 0.95
7 11 0.0016 0.12 12.4 4.6 1 23 715 737 715 737 0.98
8 11 4.5e-05 0.0033 17.3 5.6 1 23 743 766 743 767 0.95
9 11 0.0012 0.084 12.8 1.7 1 23 800 823 800 823 0.97
10 11 2.6e-05 0.0019 18.0 2.4 1 23 845 868 845 868 0.97
11 11 0.0026 0.19 11.7 3.4 3 23 906 927 906 927 0.98

Sequence Information

Coding Sequence
ATGGATCCAAGGGGCCCTCCTGAGGGGGCCCCTGCCGAGTCCTTCGAGATATCCAGCATCGACAGGGGGGCCGATACCACGGTCAACGGATGGCCGACGGATCACCCCTTCGCCTCGTCCCTGTGCGAACAGCCGAAGAAGCTGAACAACAGGCTTCTGTTCCTGACCGTGGAATATGTGGAGGATCAATCCCGACTGTTCCCCACGTATGAGCAGATCTCCTTTTCGCCGAGGGCGGCCTCCCCCCTATCCGAGTTCGAGAATCGAGTCAGCCCGCTGGATCCGAACATGAGTTCCACCGCCAGATATTCTCCCACGCCGGTCCAACTGCCTTCCTCACCCTTCCACAACTCCGTCGTCGTCCTTCAAGGCCCGTCCTCGCCCTTGATGTCCCAGCCTGAACCGAATATACGAACGAGCATTAATTACGTGACCCAGCTGACCCATCCGATCGACACTCAGGCCGTACCTCAGACAGACACTACCACAGACTTTGTTGGCAATGGGAACGAAGATGGGCTGGTGTCCAGCGTCAGCAGCGAATTGATTTTAATGCAGGAAACTGCACCTGAATTGGAATCTTCGGCGACTCCCTTAATGCTAACAGGAATACCAGGCACGGACTTCGCTCTGACCAGAGACTTCCTGGTGATGCAGGATGATCAAATAAACGTTATCAACACGTTTAAAAATCAGAACATGGAGATGGAGGACAACCCCATCGCTTTGCCATCCATTACCGAAGATGCGAACAAAGAAAACAACAATCTTGCTTTGCCGGAGTGTGATAAGGAGATTCAACAGATTACCAAAGAACCGGTGTCCACTGAGAAGAAGAAGGTGATCGAGAAGAAAGATGTGCGGAGATCCAAACGGCATATAACGGATAAGAAAGATTTCTGCATTTTTACAGGGTGCGACGACGAGTACGATGTTAATTGTGCCAAAGACGACAGCTCCAATTTGACCGACGTATGCACAATCGCGGATCAACCTGTGCCATCGCGTGCTGTAGCAACACTGCCAGGCTCATATCTTTTGTTAAACAAGCTATCTACTTCGCATGCTGCAGCGAACGGCGCGACCTACGGGATTTTTGCGAAACGTAACATTCGAAGGCGCACGCAATTCGGGCCCATCGAAGGTGTGTTGTGCACTTACGACGGCTCGCCCTTCGAGAATGCTTTGCCACTGCTCTACGAAACTGAGAATGGGGAATTCCTGAAAGTAGATGTGTCCAACGAAAACACCTCAAACTGGATGCGTTTTGTGCGGCCCGCACTGACATACAAGGAgcaaaatttaatcatttgtCAGCAGAAGGATGGAATAGTATTTTTGACCAATAGAAACATTTCGCCAAAGGAAGAGCTCAAGGCAGGTCCTAGTCCAGACTATGCAAGTCGCAGAAATTTGCCAATACTCAAACCAGACGCGAAAGATGAAAAAGAAGTGGCTAATCAAATATCCACATGGTCACGCTTGGATGGTAATTCTTACAATCGACGCATAAAGATGTTTCGCGACAGAAACGTGAAGGAGAAGGAGAACTCGCGGCAGAACAAGTGCGACAAAGAGTGGAAATGTTCCGTGTGCAACTTGATTTTCCGGAAGCCGTCCCTGCTTAACCTGCACACGGCCGTTCATTCCAACGATATCAAAATTGAGAATCAAATGTCCGCGTGCCCGCAATGCGGACTGGAATTCCACAAGCACAGCGAATTGGCGAATCATGTGTCTCAGCACGGGCGAATGGCGTTACCTAAGGCAAAGAGATTAACTCCTCTAGGTTCATACAAGTGTTCAATGTGTTACAAACGTTTTGCTACGAAGATACGATTACAACAGCACTGCTTGGCGCATGGTGCTGAGGACCAAAAACCACTGCCGTGCAGTATCTGCTTGAAGCGATTTATGAACAACTCCGCGTTGTCGGGTCATCTGAAAACGCATAAAGAAAACAAACAGGTCTTCGAGTGCCCGATGTGCAGGCAGCTATTCCGCCAAGGTACAATGCTGAAGGATCACGTTGAGACACATAGAAACCAAGACGGTATATTCAGTTGCCCTCACTGCCAGCGAACGTTCATCAAGTATTCAGTCATTCGCAAACACATTCGGGCACACCATTGCGAGAGGAAGCACAAGTGCCAGCACTGTGCGAAACGTTTCCCGACGGTCGACAAGTTGCGAATGCATTTGCTGAAGCACTCCGATCATagAGAATTTCATTGCGCCAACTGCGGTAAACAGTTTAAGAGGAAGGATAAATTGAAGGAACACATGACTAAAATACACCACTCCCAAGCGGTGGTTAACGGAGAACAAATAACGCAGAACAACCAGGCGAAGAAATTTGTGCCAAAGGTAAATCCGAACGATTACAATCGCTTCATTTACAAATGTCATCAATGCCTGGTGGGTTTCAAGCGTAGGGGAATGCTGGTGAATCACCTAGCGAAGCGACATCCCGACGTCGCTCCCGAGTCTGTGCCGGAATTGAACTTACCTATTCTGCGACAAACCAGAGACTATTATTGCCAGTATTGCGACAAGgtcTATAAAAGCAGCAGCAAACGTAAGGCGCATATCATGAAGAACCATCCTGGCGCGGCCTTGCCGCCTAGCAACCGGCAGAAAGAATCCGAATTCTCGGGACTGCCGAATCCAAGCTTCAGTCAGACAGTGGGCAGCATCACGACTAGTCCCCAAGGTTGCCAGTGGTGCCACAAGCAGTACGCCAGCAAGGCAAAGCTCTTGCAACACCAGCGCAAGAAGCACGCGCACCTGATGGAGCCGGCGGATCAAATACCGCGATCGCGGAATCGGCCGCCGCAGAATCAAAATCAACCGCCCGCGCTGAACGACAACAACTTTGTGATATCCGATTACATACAAGGATGCGACGGGGATTTCCTGAAGcagaaaataatcaaaataacgaACGACGTGGACCTGATAGGCAACGGTGGCCTGGAGATGATTGGCCAGCAGTTTGTGCGTATGCGCGACATACGTTGA
Protein Sequence
MDPRGPPEGAPAESFEISSIDRGADTTVNGWPTDHPFASSLCEQPKKLNNRLLFLTVEYVEDQSRLFPTYEQISFSPRAASPLSEFENRVSPLDPNMSSTARYSPTPVQLPSSPFHNSVVVLQGPSSPLMSQPEPNIRTSINYVTQLTHPIDTQAVPQTDTTTDFVGNGNEDGLVSSVSSELILMQETAPELESSATPLMLTGIPGTDFALTRDFLVMQDDQINVINTFKNQNMEMEDNPIALPSITEDANKENNNLALPECDKEIQQITKEPVSTEKKKVIEKKDVRRSKRHITDKKDFCIFTGCDDEYDVNCAKDDSSNLTDVCTIADQPVPSRAVATLPGSYLLLNKLSTSHAAANGATYGIFAKRNIRRRTQFGPIEGVLCTYDGSPFENALPLLYETENGEFLKVDVSNENTSNWMRFVRPALTYKEQNLIICQQKDGIVFLTNRNISPKEELKAGPSPDYASRRNLPILKPDAKDEKEVANQISTWSRLDGNSYNRRIKMFRDRNVKEKENSRQNKCDKEWKCSVCNLIFRKPSLLNLHTAVHSNDIKIENQMSACPQCGLEFHKHSELANHVSQHGRMALPKAKRLTPLGSYKCSMCYKRFATKIRLQQHCLAHGAEDQKPLPCSICLKRFMNNSALSGHLKTHKENKQVFECPMCRQLFRQGTMLKDHVETHRNQDGIFSCPHCQRTFIKYSVIRKHIRAHHCERKHKCQHCAKRFPTVDKLRMHLLKHSDHREFHCANCGKQFKRKDKLKEHMTKIHHSQAVVNGEQITQNNQAKKFVPKVNPNDYNRFIYKCHQCLVGFKRRGMLVNHLAKRHPDVAPESVPELNLPILRQTRDYYCQYCDKVYKSSSKRKAHIMKNHPGAALPPSNRQKESEFSGLPNPSFSQTVGSITTSPQGCQWCHKQYASKAKLLQHQRKKHAHLMEPADQIPRSRNRPPQNQNQPPALNDNNFVISDYIQGCDGDFLKQKIIKITNDVDLIGNGGLEMIGQQFVRMRDIR