Tcit042934.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Tiliacea citrago
Gene Symbol
-
Assembly
GCA_963921375.1
Location
OY992808.1:13503116-13552008[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.38 56 5.9 0.6 1 23 583 606 583 606 0.95
2 12 0.39 58 5.9 0.5 1 23 614 636 614 636 0.94
3 12 0.29 44 6.3 1.6 1 23 640 662 640 662 0.96
4 12 0.00072 0.11 14.5 0.9 1 20 669 688 669 690 0.94
5 12 0.0073 1.1 11.3 1.0 2 21 697 716 697 717 0.92
6 12 0.00025 0.037 15.9 0.6 2 23 733 754 732 754 0.94
7 12 0.00073 0.11 14.5 0.3 1 23 759 781 759 781 0.97
8 12 0.14 21 7.3 4.5 1 21 790 810 790 815 0.91
9 12 3.8e-05 0.0057 18.5 2.3 1 23 823 846 823 846 0.93
10 12 0.0079 1.2 11.2 0.4 1 23 852 875 852 875 0.94
11 12 0.027 4 9.5 0.3 3 19 888 904 886 905 0.89
12 12 0.055 8.2 8.5 0.9 1 23 918 941 918 941 0.97

Sequence Information

Coding Sequence
ATGAAGGAAGTTAACATAAATATAGAAGGCTATAATGTTAACGGGATATGTGTCGGCTGTTTGAATTACAATCGTCGAATGTTTTATCACCCCTCCATAAAAGAATGTTTACGTTTGCTCGGAAATATCGATGTGCCAGATGGCCTAGAAGTCCAAGTCTGCTGGGAATGCCTGGCGCGCGTCCAATCTTGTATCAACTTCAGGGAACAGATGCTCAAATCTTATGACTTTCTTATCTCGTACTCTAAAGAGCATACATTCTTGGACTCTCCGAATGACTTCAACTCTCACGCTACTACCAACATAGAGAGAACGGACGTGGAGTGTTATGAGTGTGTGCCTGAGACAGAAGTGGTGGAGGATAATGAGGTAGACGTTGATGTTAAGGAGGAAGAAGAGATTGAGGATAAGTATGGTTTTGAGGTGGCCATAAAAGAAGAAACGCTTGATGAGCCATACTTCCAAGATGTGCCAGCTGTTGACAATGACATCACATCGGATGAAGATGTGCAGCTTTCTAAACTTAAACAGAAAGAGACGGAGAAAGGGAAGAAGAAGAGAAAGAGTGACAAGAAGAAGGAAAGGGAGAGGGACAGGAGTACTAAATCACAAAAAATCCTCGCTTTGGTGCCTAAATCCCGAGCTAAATCTGATGAAGAATCCAGCGAATCTTCGGAAGATGAAGTCAAAATGTACAGGCCACGCCCCGATGCCTCCGAAGAAAGTTCCCCTGCGCGATCACTGGCGTCTTCTGTTGAAAACATAAACATCTCTGATAGTGATGACGGCGAATATCGAAAAGTTTATACCATTGCTGCCGTCCATGAAGAACCAATGCCAGCCAACAAACGACCGAGAAAGACGACACGAGGTCTCTATGACATATCACAGTTTGAAGCTGCGTATGACCAAATTGTCAATCACGGGATGTCAGTACGACAAGCGGCCAAAATGTTTAATATCACACACGTGACCCTTCAAAGATATAAGAAGAGACGTCAAACCACAAATTTTCCCGTCAAAGTGGGCTATGCACGTAACAGTTTTTATAACACGGAACAAGAAACTCAGCTAACGGAATACTTGAAAAAATATGCGGAGATATATCCCGGGTTATGCGTGAGGATAGTCAGAAAGTATGCTACGGAATTCAGCCAGAAACTGGGTTTGAAAACTCCAAAGCCTTGGGTTTATAATGACATGGCTGGCATTGATTGGTACAAAAATTTTATGTACAGAAATAAAGCTTTAGAAGATAAAATTGATCGACAAACTGCCAAAGAAAAAGTTagagttttttatgatcgactGTGGAGTATTTTATGCCAGTATAACTTTGGTTCTGAAAACATTTACTCTTTAGACGAAATTGGGGTTAATATTGAAGAGTTTAGAGATAAAATTTGGTTAATGACGACGAAAAATGGCCCTATAGCTTTGAAAGAGTCTAAAGTTATGTTCACTTATGCAGCCAACGCTAAAGGATATGCTGTACCCCCTTTATTCCTGTTACCAGGagagaaaaaagaagaaacgCCGAAAAACAACGTTGAagtcaaaatagaaaatgatgtGGTAGACTCCCCAAAACGCCAGAAGACTAAGAAGGATAAAAACCCCGAAAAGAAGAGTAGGAAGCTAAAGAATCTACCAGAAGAGTTAGTAGAACTGTACACAATGAGCAAAGAAGAAATGTGGCCTATCAGAATCCAGGATCTCAACAGCAAGGAGTTTCAGAAGCTTaagtatagATGTGATGATTGCATCATAGCCTTCAACACTGAGAAGTTGATGCATGACCATCTAAATGGAAAACATCAGCCTaaaAGCGAAGACTGCCATCAATGCTCAATATGTCAAGCCTATTTCTTAACTAAAGACAATGTGGCCGCACACAAAGCGTTACACCAACAAGGCTATAAATGTCGGGACTGTGGCTTCAATACTACTCTGAAGCGACGTATGTTGAAACATGTTGGGACTCATGCGCCGAGTGGAGATGCTCATGTGTGTCAGACTTGTGGCAGTAGTTTTAGTACTAAATCGAAGCTAACATACCACCGTGGCGTATGTTGTCAAGAAAGGCCGCAGTGTGATTGCTGTGGCAAAGTATTCGCGAACAAAATGACCCTCAAGTACCACCTCAAAATCCTGCCACAGAATAAAGATGACAAACCTAAAGAAAAGCTGTTTATACCTTGTAAAGGATGTGATAAAGTGTTTCATTCTAAGAAAAGTTATAGAGCGCATGTTGTAATCCACGACGGCCTAACCTACCCGTGCCCGATTTGCGGCAAACTGTTTCAATGGAAGCGCAACCTGGCGCGACACTCGCGCAACCATCGCGAGCGACAGGCGGGCAACTTGCACGAATGTCGTCCTTGCAGCAAGACTTTCGCAAGTAGAGACTGCTACAACAACCACATGCGGCTCAGCAAGAAGCACGTGTCGCAGGATGCTTTCccaCACGAATGTAACTACTGCGGAAAGAAATTCGCTACAAAATGGTGCCTCACCGACCACATTGACTGGGATCACTTGAAGAAAATCAAATATCAATGTAGCTTCTGTTTTAAGGCATTCAAAACAGCGAAAATATTGGTGGCTCATGTCAATAACATACACGAGGGTAAGAAAAAAGAAGCGGAGGGCGAACATTTGTGTGAAATATGCGGGAAATCGTACAGGACAGTAAAACGCCTAAAGGGCCACGTATGGGCGATGCACACAAAACGATCAAGCAGCAAGATATATAAATGTAAGCTGTGTCCGGCGACGTTCATGTGGCAGACTAGCATATACAAACATATGAAGATGATGCACGACAATAATAAGAAGAGTAAGACACCTCGCTCCGTCCAGCCTGTGAAGAAAGAGGAGCcctacccgggaatcgaactagCGAACCGAATGCAGTACTTCCAACAGAACATTGGCGGCAACTTAAATATAGTTCATATACAACCGTTGGGAATGGCTCAGAATATTGTTTAG
Protein Sequence
MKEVNINIEGYNVNGICVGCLNYNRRMFYHPSIKECLRLLGNIDVPDGLEVQVCWECLARVQSCINFREQMLKSYDFLISYSKEHTFLDSPNDFNSHATTNIERTDVECYECVPETEVVEDNEVDVDVKEEEEIEDKYGFEVAIKEETLDEPYFQDVPAVDNDITSDEDVQLSKLKQKETEKGKKKRKSDKKKERERDRSTKSQKILALVPKSRAKSDEESSESSEDEVKMYRPRPDASEESSPARSLASSVENINISDSDDGEYRKVYTIAAVHEEPMPANKRPRKTTRGLYDISQFEAAYDQIVNHGMSVRQAAKMFNITHVTLQRYKKRRQTTNFPVKVGYARNSFYNTEQETQLTEYLKKYAEIYPGLCVRIVRKYATEFSQKLGLKTPKPWVYNDMAGIDWYKNFMYRNKALEDKIDRQTAKEKVRVFYDRLWSILCQYNFGSENIYSLDEIGVNIEEFRDKIWLMTTKNGPIALKESKVMFTYAANAKGYAVPPLFLLPGEKKEETPKNNVEVKIENDVVDSPKRQKTKKDKNPEKKSRKLKNLPEELVELYTMSKEEMWPIRIQDLNSKEFQKLKYRCDDCIIAFNTEKLMHDHLNGKHQPKSEDCHQCSICQAYFLTKDNVAAHKALHQQGYKCRDCGFNTTLKRRMLKHVGTHAPSGDAHVCQTCGSSFSTKSKLTYHRGVCCQERPQCDCCGKVFANKMTLKYHLKILPQNKDDKPKEKLFIPCKGCDKVFHSKKSYRAHVVIHDGLTYPCPICGKLFQWKRNLARHSRNHRERQAGNLHECRPCSKTFASRDCYNNHMRLSKKHVSQDAFPHECNYCGKKFATKWCLTDHIDWDHLKKIKYQCSFCFKAFKTAKILVAHVNNIHEGKKKEAEGEHLCEICGKSYRTVKRLKGHVWAMHTKRSSSKIYKCKLCPATFMWQTSIYKHMKMMHDNNKKSKTPRSVQPVKKEEPYPGIELANRMQYFQQNIGGNLNIVHIQPLGMAQNIV