Tcit043347.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tiliacea citrago
Gene Symbol
egg
Assembly
GCA_963921375.1
Location
OY992809.1:5274093-5328756[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.6 1.2e+04 -2.5 0.1 28 38 802 831 790 832 0.62
2 2 5.3e-13 3.8e-09 37.5 0.0 4 73 863 925 860 929 0.88

Sequence Information

Coding Sequence
ATGCTGTATTCTAAAAGGGGCTCTGATGGCTCAAGCGGTCAAATTGAATACAAGCAAGTCTTAGCTGAAGAGAAACAAAAGCAAAAGCACTCACCATCTAAATCGCCGAACAAGAGCATTAAGTCGCCTAAGCAATCACCGAGCAAGTTGAGCCAGTCGCCCTGTAAGCAATCCCCGATCAAGATGAAGAATTTGGCTATCACCGCCCAAGAAGCTAGCTCGGTTGTCAATATTGTGGATTTGGAGGAGAGCAGCTCTTCTGAAGATGACATACAAGAAGTACAAAAACAACCGGAACCAGAGGCAACAGAGGGCGAAAAATCTCTTTCCCCGGAATCAGATGTTACCAACGTTAACATACCAACGGGCATAGACATAATGTGTACTTCCGGCGGAAATATGTCAGAGATAACGACTAAAGACAACCTATCCCAGGTTGTTATCAGTGGCGTGCCTAAGCCGCCGCCGCATAAGCCTgcCAGACTGAATACGAGTGAAGTCACAATCAAAACTGGTAGTAATACTGAACCACTGATAATACCTGAAACTACGattAATGATCAGACTCAAACACAGGCTAAACCTAAACTGAGTTTAGAAATATTCAGTCTGGATTCTGACGAGGATGACGGTGCAGCAAAAGaaaaaTTACCTCCAGCTTCCCCCGACAAAATGACGGACTTAGAACTGGAAAAAGCTAAAGAAACATCCAAATGTATCAACTATTGTTGCACGAGCGGCAACAAAGTGCCTTACAAGGTCGCGGAGGCGTCAGTGATCGCTTACTACGACGCGGGCAGGAAGAGACGCTCCGTGGTGTGCCAGCCGTGCGCCGATGTGGTCGCTGGGAGGACTAAGAATCTAATCCAAGGCATAAAGGATCTAACTCCACTGTTGAACCTAGATATGAGCAAGTTATCACAAGACCTGGTGGAGATATCTGACTCAGAGTCCGAAGATGAGGATATGAGTCCTGAAGAACCCAAGGAGAGTATCGGAGAGAAGGGGGCTAAATTCATAGAAGACAATCTAGCCAAGTTTTTGAACGACACGTGGAACAAATACGAGATGGACGTGCGGCTCAAAGAGACACAGATTATGTTAGACGATGAGATTGATAAACTTGAACAGGACAGCAAAGAAATAGACGCAATGCTGAACGAGTGTCAGGTAGCGACAGACAAGCTTCGCTGTGAGCTATACGCGACGTTCGAGTGCCGGCGTCAACAACAATCTTCTTTAGTTATTTACGACACGCCTGACTCTAAATATATCGGACTAGAAGAGCAAGTAAATCCTCCTGCCGTTGTTGAATCAATtgaaACTCGTCAAGCCAAGCGTCGTTTGTCGTCAACCTGTGAGACTCCAGCCAAACGTCCTGCCATACCTCTTGGATATGCTCCTTTGGATGGCGGAGACTCTAAGgAGAAAGCAGCTATCCCCGGACCAGATATTAAGTTAGATGACGATAAAGACATATCAGTAGTGAAACTCTCGGCGGAAGCCGCCCCAGCCGACCTGCCCCCTCCCGGTGAGATCTCCCGCCCCCCGCTGCGCGTGGGCATGCCGGTCTACGCAATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAGGGTGGTGGAGATACAGCCCAAGAATACGAGTGGGGGCAACCCATTCTCGGTCTGTCTCGTGAAATTCGACCATAAAGTCAAGACTAATGGGAAAGTGTTGCATGCAAGGTGCATCGCGTATTCTGAGCCCGCTGATGTTAGAATGACTATTGgtaCACGTCTTATAGCCCTGTTCAAGGATTCGAACAAGCGTGAATCTTACTACTCAGGCGTAGTAGCTGAAATACCAAATCCTGTCAATAATTATAGGTACCTAGTTTTCTTCGACGACGGCTACGCTCAGTACGTCCAACATCAATTCACCCGCCTAGTATGCGAAAGCTCCCCCTTAGTATGGGAGGAAGTGCATCCATTCTCGCGCGAATTCGTCCGCGAGTACCTGATGGCGTACCCAGAGAGACCCATGGTCAGGCTGCATGAGGGGCAGCATTTGAAGACCGAGTGGAACGGAAAATGGTGGTCATCCCGAGTGACCCGCGTAGACGCGTCGCTGGCTCAAGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGGTCTACCGCGGGTCCACGCGCCTCGCGCCGCTCTACCTCGAGCTGCGCGCCGCCGAGCGACACCGGCCCCGACCCATGCCTAGGAGCAAGGCGCAGCCTAGGTTCAATATGCCGTACGTGGAGTACACTCGGTCGGATGAGCAGGAATCGAACAAGCAAGTGGATGCGCAGGCgcagcaacaacagcagcagcagcaggagcAGATACAAAATGAGGAGATACGTCGCCAACGCTCCGTAGCCAAGAAGTCTACCTCAGCACCTCCTCAAGTGATCCCGCCATCGCAACAGATTATGCCCCCCACCCACATGGATCCTGTCACCAGCAGAGTTGTGTACTACACACCAAAGAACGCGGTGAAACCATTGAAGATGGTTCCACACAGATGCGGTCCGAGATGCAAGCGTAGCGACGTACTCTCACTAAAGGAGTTGAGGACTTACAATCCGTTAGCCAAACCACTACTGAGCGGATGGGAGAGACAAATAGTCCGCTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCCTGCGGCCGTCGCTTACGAAACATGCGCGAGTTACATCACTACTTACGTTCAATAGACAGCGACTTGCCTGTAGATCTGTTTGACTTCCACTACTCAACGCATTGTCTAGCGGAGTTCGTGCTCAACAAATGTCTTGTGGGGAAAAaggACCTCTCCCACGGCAAAGAGAACGTCCCAGTGCCCTGCGTGAACTACTACGACGACTCCTTACCGGAGTTCTGTTCGTACAACACCGAGCGCACTCCCACCGCCGGCGTGCCGCTTAACCTGGAGCCCGAGTTTCTGTGCGGCTGCGACTGTACCGACGACTGTCAGGATAAATCAAAATGCGCTTGCTGGAAAATGACACTAGAGGGCGCTCGCACCATCGGGCTACGTGGACCTAATGTGGGATACGTGCACAAACGATTGCCTGAACCGTTACCTTCTGGGATATACGAGTGTAATTCTAGGTGTAAATGCAAGCATACGTGTCTAAATCGCGTGGCGCAGCATCCGCTACAATTAAAATTACAGGTTTTCAAAACTCCGAACCGTGGTTGGGGTATCCGGGCGCTGAACGACGTTCCCAAAGGATCCTTCCTCTGCGTGTACGCCGGTAACCTGCTCACTGATGCCACAGCTAATTTGGATGGTTTGAACGAGGGTGACGAGTATTTAGCAGAATTAGATTACATAGAAGTAGTGGAACAAATGAAAGAGGGATACGAAGAAGATATTCCTGAGGCTGATAAGAAACTAGATAAGAAAGAAACTAAGGCTGATGACGACAGTGACGAGGATGAGCAGTCATCCTCCGAGGATGAGCAGAAGGCTGATAAGAATGACAAGGAGGATGATGACTTCAGACCGGGATACATTGGACTAGGGGTATCGGAGTTTAGCAAACGCCTCCGTAAACGCGAGAAATCAAAGAAAGATAAAGAAAAATCGGTGGCCGATgagaaagaaaaggaaaaagatACGACTAAAGAATCTAATGCTGAAGAGGATTGTATTACTATTAGTGATGATGAAGaagTTCGAGAACCTTCCAGATTCATGGCACAAGCGGACATGGGAGCTAGCGCATATATTTCTAAATACAAGTCTGTTCGCACGTTGTTCGGTAAAGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATcATTCCTGCTGCCCGAATGTCTTCGTACAAAACGTGTTCGTAGACACCCACGACCCTCGCTTCCCTTGGGTGGCGTTCTTCGCGCTGTCACACATCAAAGCAGGTACCGAGCTCACTTGGAATTACAACTATGACGTGGGATCTGTTCCCGGGAAGATTCTGTACTGTTACTGTGGAGCTCCTAACTGTAGGGGACGACtattgtaa
Protein Sequence
MLYSKRGSDGSSGQIEYKQVLAEEKQKQKHSPSKSPNKSIKSPKQSPSKLSQSPCKQSPIKMKNLAITAQEASSVVNIVDLEESSSSEDDIQEVQKQPEPEATEGEKSLSPESDVTNVNIPTGIDIMCTSGGNMSEITTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTGSNTEPLIIPETTINDQTQTQAKPKLSLEIFSLDSDEDDGAAKEKLPPASPDKMTDLELEKAKETSKCINYCCTSGNKVPYKVAEASVIAYYDAGRKRRSVVCQPCADVVAGRTKNLIQGIKDLTPLLNLDMSKLSQDLVEISDSESEDEDMSPEEPKESIGEKGAKFIEDNLAKFLNDTWNKYEMDVRLKETQIMLDDEIDKLEQDSKEIDAMLNECQVATDKLRCELYATFECRRQQQSSLVIYDTPDSKYIGLEEQVNPPAVVESIETRQAKRRLSSTCETPAKRPAIPLGYAPLDGGDSKEKAAIPGPDIKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVVEIQPKNTSGGNPFSVCLVKFDHKVKTNGKVLHARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLMAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWVYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEQESNKQVDAQAQQQQQQQQEQIQNEEIRRQRSVAKKSTSAPPQVIPPSQQIMPPTHMDPVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNVGYVHKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKETKADDDSDEDEQSSSEDEQKADKNDKEDDDFRPGYIGLGVSEFSKRLRKREKSKKDKEKSVADEKEKEKDTTKESNAEEDCITISDDEEVREPSRFMAQADMGASAYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00622853; iTF_01340138; iTF_00237602; iTF_00425412; iTF_00810094; iTF_00851827; iTF_00172985; iTF_00121468; iTF_01526047;
90% Identity
iTF_00622853;
80% Identity
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