Xict035674.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Xanthia icteritia
Gene Symbol
egg
Assembly
GCA_949128155.2
Location
OX421959.2:8455643-8506924[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.5 1.2e+04 -2.8 0.1 29 38 747 756 716 757 0.67
2 2 6.3e-13 2.9e-09 37.6 0.0 4 73 788 850 785 854 0.88

Sequence Information

Coding Sequence
ATGAAGAATTTGGCTATCACCACGCAAGAAGCTAGCTCGGTTGTAAACATTGTGGATTTGGAGGAGAGCAGTTCTTCTGAAGATGATATACAAGAAGTACAAAAGCAACCGGAACCAGAGACAGCAGAAGGCGATAAATCTCCTTCCCCGGAATCAGATGTTACTAATGTTAAAATACCAACGGGCATAGACATAATGTGTACTTCCGGCGGAAATACGTCAGAGATAACGACTAAAGATAACCTCTCTCAGGTTGTTATCAGTGGCGTGCCTAAACCGCCGCCGCATAAACCTgccAGATTAAATACCAGTGAAGTTACGATCAAAACTGTTAGTAACACCGAACCATTGGTTATACCTGAAACTAAGATTAATGAACAGACTCCAGCACAGTCTAAACCTAAACTGAGCCTAGAAATATTCAGTCTAGATTCTGACGACGATGAAAGTGGAGCTAAAGaaaaatcACTTGCAGCTTCCCTCGACAAAATGACAGCCTTAGAACTAGAAAAAGCTCGAGAAACATCCAAGTGTATCAACTATTTTTGCACAAGCGACAACAAAGTCTCTTACAAACAGGCCGAGGCGTCAGTGGTCGCGTACTACGACGCAGGCAGGAAGAGACGCTCCATGGTGTGTCAGCCATGCGCAGATGTAGTCGCTGCTAGGACTAAGAATCTAATTCAAGGAATAAAAGACCTAACGCCACTGTTAGAGCTGGATATGGGCAAGTTATCACAAGATCTGGTGGAAATATCTGACTCGGAGTCTGAAGATGAAGAAATGAGTCCTGAAGAACCCAAGGAGAGTATAGGAGAGAAGGGCGCGAAATTCATAGAAGATAATCTAGCCAAGTATTTGAATGACACTTGGAAAAAATATGACATGGACGTGCGGCTCAAAGAGACTCAGATCATGTTAGATGATGAGATCGAAAAACTTGAACAGGACAGCAAAGAAATAGACGCAATGCTTAACGAGTGTCAAGTAGCGACAGACAAGCTTCGCTGTGAGCTATACGCGACGTTCGAGTGTCGACGTCAACAACAACCCTCATTAGTTATATGCGACACGCCTGATTCTAAATATATTGGACTAGAAGAGCAACCAAACCCTCCAGCCGTTGCCGAATCAATTGaaACTCGTCAAGCCAAGCGTCGTTTGTCGTCAACCAGTGAGACTCCAGCCAAACGTCCTGCTATACCTCTTGGATATGCTCCTTTAGATTCCAGCGACTCTAAGAAAGACATATCGGTAGTGAAGCTCTCAGCGGAAGCCGCTCCCGCAGACCTGCCTCCCCCTGGAGAGATATCCCGCCCTCCACTGCGCGTGGGCATGCCGGTGTATGCCATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAGGGTGGTGGAGATACAGCCCAAGAATACGAGTGGggGCAACCCATTCTCTCTGTGTCTTGTGAAATTCGACCACAAAGTCAAGACTAATGGGAAAGTATTGCAAGCGAGGTGCATCGCGTATTCTGAGCCCGCTGATGTCAGAATGACAATTGgTACTCGTCTTATAGCTCTGTTCAAGGATTCGAACAAGCGTGAATCTTACTACTCTGGTGTTGTCGCTGAAATCCCTAATCCAgtcaataattatagATATCTAGTATTCTTCGACGATGGCTACGCTCAGTACGTCCAACATCAATTCACCCGCCTTGTCTGCGAAAGCTCCCCCTTAGTATGGGAGGAGGTGCATCCGTTCTCGCGGGAATTCGTCCGCGAGTACCTGCTGGCTTACCCAGAGAGACCTATGGTCAGGCTACATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGTCCTCCCGCGTGACCCGCGTGGACGCGTCGCTGGCGCAGGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGGTGTACCGCGGCTCCACGCGCCTGGCGCCGCTGTACCTGGAGCTGCGCGCCGCCGAGCGCcaccgcccgcgccccatgccGCGCAGCAAGGCGCAGCCACGGtTCAATATGCCGTACGTGGAGTACACTCGGTCGGATGAGCAGGAATCGAGCAAGCCAGTGGATGCGCAGGCGCAGCAACAACAACAgcaacagcagcagcagcagatACAAAATGAGGAGATACGTCGCCAACGCGCCGTGGCTAAGAAGTCTACCTCAGCACCTCCTCAAGTGCTCCCGCCATCGCAACAGATCGTGCCCCCCACACACACGGATCCCGTCACCAGCAGAGTTGTGTATTACACACCAAAGAACGCGGTgaaaccattgaagatggtgccACACAGATGCGGTCCAAGATGCAAGCGAAGCGACGTGCTCTCACTAAAAGAGTTGAGAACTTATAACCCATTGGCAAAACCACTGCTCAGCGGATGGGAAAGacAAATAGTCCGCTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCCTGCGGCCGTCGCTTACGAAACATGCGCGAGTTACATCACTACTTACGTTCAATAGACAGCGACTTGCCTGTAGATCTCTTTGACTTCCACTACTCTACGCATTGTCTGGCAGAATTCGTGCTCAACAAGTGTCTTGTGGGGAAAAAGGACCTCTCCCACGGCAAAGAGAACGTCCCAGTACCCTGTGTGAATTATTACGACGACTCCTTACCGGAGTTCTGTTCGTACAACACCGAGCGCACTCCCACCGCCGGCGTGCCGCTCAACCTGGAGCCCGAGTTCTTGTGCGGCTGCGACTGTACCGACGACTGCCAGGATAAATCAAAATGTGCTTGTTGGAAAATGACGCTAGAAGGCGCTCGCACCATCGGGCTACGTGGACCTAATGTGGGCTATGTCTATAGAAGACTGCCCGAACCGTTACCTTCTGGGATATACGAGTGTAATTCTAGGTGTAAATGCAAGCATACATGTCTTAACCGCGTGGCGCAACATCCATTACAATTGAAATTACAGGTTTTCAAAACCCCGAACCGTGGTTGGGGTATCAGAGCGCTGAACGACGTTCCCAAAGGCTCCTTCCTTTGTGTGTACGCTGGTAACTTGCTCACTGATGCTACGGCGAATTTGGATGGTTTGAACGAGGGTGATGAATATCTAGCAGAATTAGACTACATAGAAGTAGTCGAACAAATGAAAGAGGGATATGAAGAAGATATTCCTGAGGCTGATAAGAAATTAGACAAGAAAGAAGTTAAGGATGATGAAGACACTGACGAGGTTGAACCGTCATCCTCCGAAGATGAGGAGAAGGCTGATAAGAATGACAAAGAGGATGATGACTTCAGACCGGGATACATTGGACTAGGAGTTACGGAGTTCAACAAACGCCTCCGTAAACGCGAGAAATCAaagaaagataaagaaaaatCTGCGACTGATGAGAAAGAAAAGGAGAAAGATACGACTAAAGAAGCCAATGCTGAAGAAGATTGTATTACTATTAGTGATGATGAAGAAGTACGAGAACCATCGAGATTCATGGCTCAAACAAACATGGGAGCTAACGAGTATATTTCTAAATACAAATCTGTTCGCACGTTATTCGGTATGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCACTCCTGCTGCCCGAATGTCTTCGTGCAGAACGTGTTCGTGGACACCCACGACCCTCGTTTCCCTTGGGTGGCGTTCTTCGCGCTATCACACATCAAAGCAGGTACCGAGCTCACTTGGAACTACAACTATGACGTGGGTTCCGTTCCAGGAAAGATACTTTACTGTTACTGTGGAGCTCCTAACTGTAGGGGCAGActgttgtaa
Protein Sequence
MKNLAITTQEASSVVNIVDLEESSSSEDDIQEVQKQPEPETAEGDKSPSPESDVTNVKIPTGIDIMCTSGGNTSEITTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTVSNTEPLVIPETKINEQTPAQSKPKLSLEIFSLDSDDDESGAKEKSLAASLDKMTALELEKARETSKCINYFCTSDNKVSYKQAEASVVAYYDAGRKRRSMVCQPCADVVAARTKNLIQGIKDLTPLLELDMGKLSQDLVEISDSESEDEEMSPEEPKESIGEKGAKFIEDNLAKYLNDTWKKYDMDVRLKETQIMLDDEIEKLEQDSKEIDAMLNECQVATDKLRCELYATFECRRQQQPSLVICDTPDSKYIGLEEQPNPPAVAESIETRQAKRRLSSTSETPAKRPAIPLGYAPLDSSDSKKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVVEIQPKNTSGGNPFSLCLVKFDHKVKTNGKVLQARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLLAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWVYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEQESSKPVDAQAQQQQQQQQQQQIQNEEIRRQRAVAKKSTSAPPQVLPPSQQIVPPTHTDPVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNVGYVYRRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKEVKDDEDTDEVEPSSSEDEEKADKNDKEDDDFRPGYIGLGVTEFNKRLRKREKSKKDKEKSATDEKEKEKDTTKEANAEEDCITISDDEEVREPSRFMAQTNMGANEYISKYKSVRTLFGMDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01441120;
90% Identity
iTF_00622853;
80% Identity
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