Aanc027861.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apamea anceps
Gene Symbol
egg
Assembly
GCA_951799955.1
Location
OX637528.1:4328193-4380562[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.9 1.1e+04 -3.0 0.1 29 38 893 902 863 903 0.65
2 2 1.5e-13 8.2e-10 39.0 0.0 4 73 934 996 931 1000 0.88

Sequence Information

Coding Sequence
ATGTGTGACAGCACCTCCCAGGATAAGGCGGAGAAGATGGATGTGGAAGAGGAATATGGGACTgTGGAGCTACAGGCAGCAACATTAAATGAGATGAATGATGAAGCACAGGCGGCTGTTGACGCGTTGTTGAACGCTGATAATCCCGCCAGTGAACAAGTTCAGgatCAACAAGAAACCACAGAACCAATGGACATAGAGACGGTGAAGCTGTCAGATACGTCCGACAATGAGGTGGACGTTGAGCCTACGGAAGTTCAACAGGCTGTGGCTGAACCAAGCAAGGAGGCTGAAGAAAAACAAACGCGCTCACCATCTAAGTCACCGAGCAAGAGCAGCACATCGCCCAAGCAATCGCCAAGCAAGTCAAGCCAGTCGCCCTGTAAGCAATCCCCGAGCAAAATGAAGAATTTGGCCATCGCCACGCAAGCAGCTAGCTCGGTGGTCAATATTGTGGATTTGGAGGAGAGCAGCTCTTCTGAAGATGACATAGAAGAAGTAGAAAAGCCACCGGAACCAGAGACAACACAAGACGACAAACCTCCTTCTCCGGAAACAGATGTTACCAACGTTAACATACCAACGGGCATAGACATAATGTGTACTTCCGGCGGAAGTACGTCAGAGATAACGACTAAAGACAACCTCTCCCAGGTGGTTATCAGTGGAGTGCCTAAGCCGCCGCCGCATAAGCCTGCCAGATTGAATACGAGTGAAGTTACAATCAAAACTGTTAGTAATACAGAACCGTTGATTATACCTGAAACTAAGATTAATGAACAGACTCAAACACAGTCTAAACCTAAACTAAGTCTAGAAATATTCAGTCTAGattctgatgatgatgaaagcgcTGCTAAAGAAAAAGCATCACCATCATCCCCTCACAAAATGACAGCCTTGGAACTAGAAAAAGCTCGAGAAACATCCAGATGCATCAACTATTGTTGCACGAGCGACAACAAAGTGCCTTACAAACTGGCGGAGCCGTCAGTGGTCGCGTACTACGACGCGGGCAGGAAGAGACGCTCCATGGTGTGCCAGCCATGCGCCGATGTGGTCGCTGCTAGGAGTCAGAATCTAATCCAAGGCATAAAGGATCTAACTCCACTGATAGACCTGGACATGGGCAAGTTATCTCAAGACCTGGTGGAGATATCCGACTCGGAGTCTGAAGATGAGGTTACGAGTACTGAGGAACCTAAGGAGAGTATCGGAGAGAAGGGGGCTAAATTCATAGAAGACAATCTGGCTAAGTATTTGAACGACACGTGGAAGAAGTATGACATggacacgcgcctcaaagagacacAGATTATGCTAGATGATGAGATTGAGAAACTTGAACAGGACAGCAAAGAAATAGACGCAATGCTAAACGAGTGTCAGATAGCGACAGACAAGCTTCGCTGCGAGTTATACGCGACCTTCGAGTGTCGGCGAGAGAATCTACCCTCTTTAGCTATATACGACACGCCTGACTCTAAATATATTGGACTAGAAAACCCTCATTCTACAGCTTCCGAGACAATTGAAACTCGTCAAGCCAAGCGTCGTTTGTCGTCACAAAGTGAGACGACTCCAGCCAAACGTCCTGCTATACCCCTTGGATACGCTCCTTTAGATGGCGGCGACTCAAAGgaAAAAGCAGCAATCCCCGCGCCAGATAGCAAACTAGATGATGACAAAGATATATCAGTAGTGAAGCTGTCAGCTGAAGCCGCCCCCGCAGACCTGCCTCCGCCCGGCGAGATCTCGCGCCCGCCGCTACGCGTGGGTATGCCGGTGTACGCCATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAGAGTGTTGGAGATACAGCCCAAGAATACGTCTGggGGCAACCCATTCTCTGTGTGTCTTGTGAAATTCGACCATAAAGTGAAGACGAATGGAAAAGTGTTGCATGCAAGATGCATCGCGTATTCTGAGCCCGCTGATGTTAGAATGACTATTGGTACTCGCTTAATAGCCCTGTTCAAAGATTCGAACAAGCGCGAATCTTACTACTCTGGTGTTGTAGCAGAAATACCCAACCCAGTCAATAATTATAGATACCTAGTATTTTTCGACGACGGCTACGCTCAATACGTCCAACACCAGTTCACCCGTCTAGTCTGCGAAAGTTCTCCCTTAGTATGGGAGGAAGTACATCCATTCTCGCGGGAATTCGTCCGCAAGTATCTAATGGAGTATCCAGAGAGACCGATGGTCAGGCTGCATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGAGTGACGCGTGTAGACGCGTCGCTGGCGCAGGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGATCTATCGCGGATCCACGCGCCTCGCGCCGCTCTACCTCGAGCTGCGCGCCGCTGAACGACACCGACCCAGACCCATGCCTAGGAGCAAGGCGCAGCCTAGGTTCAATATGCCGTACGTAGAGTACACTCGGTCGGATGAGCAGGAGTCGAACAAGCAAGTGGATGCGCAGGCGCCGCAGCAACAgcaacagcagcagcagcagataCAAAATGAGGAGATACGTCGCCAACGCGCCGTAGCCAAGAAGTCTACCTCAGCACCTCCCCAAGTGCTCCCGCCATCACCACAGGTTATGCCCACCCAGTTGGATACGGTCACCAGCAGAGTTGTGTACTACACACCAAAGAACGCGGTGAAACCGTTGAAGATGGTGCCGCACAGGTGTGGCCCGAGATGCAAGCGAAGCGACGTACTCTCACTAAAGGAATTGAGAACTTATAATCCACTGGCTAAACCACTGCTCAGCGGATGGGAAAGACAAATTGTCCGCTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCCTGCGGCCGGCGCTTACGCAACATGCGCGAGTTACATCAGTACTTACGAGCTATAGACAGTGACTTGCCTGTAGACCTGTTTGATTTCCACTACTCTACGCATTGTCTGGCCGAGTTCGTGCTGAACAAGTgtttagttgggaaaaagGACCTCTCCCACGGCAAAGAGAACGTCCCAGTGCCATGCGTGAACTACTACGACGACTCCTTACCGGAATTCTGTTCGTACAACACCGAACGCACTCCCACCGCCGGTGTGCCACTCAACCTGGAGCCCGAGTTCCTGTGCGGTTGCGACTGTACTGATGACTGTCAGGATAAATCAAAATGCGCTTGTTGGAAAATGACGCTAGAGGGCGCTCGCACCATCGGGCTACGTGGACCTAACTTGGGCTATGTTTATAAGAGACTACCTGAACCGTTACCGTCTGGGATATACGAGTGCAATTCTAGGTGTAAATGCAAGCATACATGTTTAAATCGCGTGGCTCAGCATCCACTACAGTTAAAATTACAAGTTTTCAAAACTCCGAACCGCGGTTGGGGTATCCGAGCACTGAACGACGTGCCCAAAGGCTCCTTCCTATGTGTGTACGCTGGGAACCTGCTCACTGATGCTACTGCTAACTTGgacGGTTTGAACGAGGGTGACGAATATCTAGCAGAATTAGATTACATAGAAGTTGTAGAACAGATGAAGGAGGGTTATGAAGAGGACATTCCTGAGGCCGACAAGAAATTAGACAAGAAAGAAGGTAAGGAAGGTGACGACAGTGACGAGGATGAGCCGTCATCCTCCGAGGATGAGGAGACGGCGGATAAGACTGACAAGGAAGATGATGACTTCAGACCGGGATACATTGGACTTGGCGTTACGGAGTTCAGCAAACGCCTCCGTAAACGCGAAAAATCAAAGAAAGATAAAGAAAATGCAGCGGGTGATGAGAAAGAAAAGGACAAAGATACGACTAAAGAAACGACTAAAGAATCGAATGCTGAAGAGGATTGTATTACTATCAGTGATGATGAAGAAGTACGAGAACCTTCAAGATTCATGGCGCAAGCAAACATGGGAGCTAACGAATATATATCTAAATACaagtcTGTTCGCACGTTATTTGGTAAGGACGAGGCATGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATAtctcaatCACTCCTGCTGCCCGAATGTCTTTGTACAAAACGTGTTCGTGGACACCCACGACCCTCGCTTCCCCTGGGTGGCGTTCTTTGCACTCTCACACATAAAAGCGGGCACCGAGCTCACCTGGAACTACAACTATGACGTGGGTTCGGTTCCCGGGAAGATACTTTACTGTTATTGTGGAGCTGCTAACTGTAGGGGACGACTGTTGTAA
Protein Sequence
MCDSTSQDKAEKMDVEEEYGTVELQAATLNEMNDEAQAAVDALLNADNPASEQVQDQQETTEPMDIETVKLSDTSDNEVDVEPTEVQQAVAEPSKEAEEKQTRSPSKSPSKSSTSPKQSPSKSSQSPCKQSPSKMKNLAIATQAASSVVNIVDLEESSSSEDDIEEVEKPPEPETTQDDKPPSPETDVTNVNIPTGIDIMCTSGGSTSEITTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTVSNTEPLIIPETKINEQTQTQSKPKLSLEIFSLDSDDDESAAKEKASPSSPHKMTALELEKARETSRCINYCCTSDNKVPYKLAEPSVVAYYDAGRKRRSMVCQPCADVVAARSQNLIQGIKDLTPLIDLDMGKLSQDLVEISDSESEDEVTSTEEPKESIGEKGAKFIEDNLAKYLNDTWKKYDMDTRLKETQIMLDDEIEKLEQDSKEIDAMLNECQIATDKLRCELYATFECRRENLPSLAIYDTPDSKYIGLENPHSTASETIETRQAKRRLSSQSETTPAKRPAIPLGYAPLDGGDSKEKAAIPAPDSKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVLEIQPKNTSGGNPFSVCLVKFDHKVKTNGKVLHARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVRKYLMEYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEQESNKQVDAQAPQQQQQQQQQIQNEEIRRQRAVAKKSTSAPPQVLPPSPQVMPTQLDTVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHQYLRAIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNLGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKEGKEGDDSDEDEPSSSEDEETADKTDKEDDDFRPGYIGLGVTEFSKRLRKREKSKKDKENAAGDEKEKDKDTTKETTKESNAEEDCITISDDEEVREPSRFMAQANMGANEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAANCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01441120;
90% Identity
iTF_00237602;
80% Identity
-