Lqua012025.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leptura quadrifasciata
Gene Symbol
ZFHX3
Assembly
GCA_963675555.1
Location
OY776673.1:219065384-219084924[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0022 0.41 13.3 0.8 1 23 83 106 83 106 0.95
2 14 0.044 8.2 9.2 2.2 2 22 192 212 192 215 0.90
3 14 0.14 25 7.7 1.6 1 23 227 252 227 252 0.91
4 14 0.0062 1.2 11.9 1.6 1 23 270 292 270 292 0.97
5 14 0.0013 0.25 14.0 0.7 2 23 299 321 298 321 0.94
6 14 0.00036 0.066 15.8 3.1 1 23 430 454 430 454 0.92
7 14 0.011 2 11.2 0.6 1 22 474 495 474 498 0.89
8 14 0.0021 0.39 13.4 0.2 1 23 547 571 547 571 0.93
9 14 0.0022 0.4 13.3 0.0 2 21 634 653 633 654 0.94
10 14 0.63 1.2e+02 5.6 2.5 2 19 767 784 766 789 0.90
11 14 0.00023 0.042 16.4 2.5 1 23 1359 1381 1359 1381 0.99
12 14 0.0016 0.29 13.8 0.3 1 23 1476 1498 1476 1498 0.98
13 14 0.012 2.3 11.0 0.4 2 23 1646 1668 1645 1668 0.96
14 14 2.7 5e+02 3.6 3.2 3 23 1927 1949 1925 1949 0.89

Sequence Information

Coding Sequence
ATGTTCTTTTATTCTTCTACAGAACGAAGAGATAGCATCAACTCCGAGCTCAGTCAAATTGAAGCGAGCAGGGATCAAGTTAAGTCGGAACCACGAGAGGAAGGCGATGATGCGAACAACAGCGAAAGCGGATCACCGCAGCACATGTGTCCGTTCTGCGAATACAGCAGCGATTCGGAGATGCGCATACAAGCCCATATCCTTGCCCAACATGGCACAAATAACGCGTCCATGCCGGAAATCCTCTTTCACTGCCCCTTATGTCAGGATGCCTTCAAAGATCGCACCAACTTGGAACGCCACGTTATGCAAATACATTCGGTGAACAGCGAGGGCTTGCAGCGCTTATTAATGTTAGTTGATCAAAGCCACTGGTTGAACCAAGCCTCTAGGACGCCAACACCGAATAATTCTCTAAATCAAACTCAAACGACGCCCAATCAAATTGTATCACCGACTTCAGTGTCTTCCAAAGAATCAAATAAGCTCGAAAAAAGTGACCCTAGTCACGCGGATGCCGAGCCAGACTTGATGTCGCCTGTCAGCGACGACACGACCGAGTCCGAATCGGAGCGCTGCGGGACGTGCTTCAAGACATTTCGGAACATCGACGAACTGTGCTACCACCAAAACGAAACCGGACACCTGGAGATCAAACAGACCCCCAGCGGGCCGGGATACATGTGCTGGAAGAAAGGATGCAACCAGTTTTTTCCAACAGCGCATACTTTACAAATGCATTTCAAGGAAGTACACGCCAAAAATTCGATCGCGAACATGTCGGTGTCGGAAAAGCACGTATACAAGTACCGGTGCAACCAGTGCTCTTTAGCATTTAAGACGTTAGAAAAATTACAACTACATTCTCAATATCACATGATCAGAGACGCTACAAAATGTGTGTTGTGTGGACGTAGCTTTCGATCACTCGTCGCGTTGCACAAGCATGTGGAAAGCGTACACTCAGAACTAACGGACGAAGAATTGAACGCCTACAAGCAGAGTTTAATGAACAACCCGTTACTGTTGGCGGGGTTGCAAGGTCAAGTGCTAGACAGCTCCACGAACGATATTCTAAAGAAAGAATCGCTACGACACGACGACAACGAGTCTGGCGAATGCGATGACAGCAAAGAACTAAACACTAGTCAATCGTTGGACGATAGCAATCAGAATGACGGCGAGAATTCGGACGATAGCATAATTTACAAGGATCAACAATTTTTAGAAGACTATCTGAACAGCCAGGCCATCGCGGAGGACAGTTATAACGATCccaatagaaaatataaatgccACCGCTGCAAAGTCGCCTTTACAAGACAGAGCTATTTAACCGCCCACAACAAAACACTCTTACATCGAAAGGGTGAAAAGCTGAGCTACCCTATGGAGAAATACCTGGACCCTAACAGGCCATACAAATGCGACGTATGTAAAGAGAGTTTTACGCAGAAAAATATATTACTCGTTCATTACAACTCGGTCAGCCACTTGCACAAATTAAAACGAGCAATGCAGGAACAACAGAACAATAACAACAATCCTCCCGTCTCGCCTATCACGGGGAGCACGCAACCTCAAAATTTAACTTTAACTCCGAAAAGCTCATCCTCGGAGGAAGACGATAAGAAAAGATATCGCTGTAATATCTGTAAGGTTGCGTACACGCAAGGCAGCACTCTCGACATTCACATGCGGAGCGTCCTCCACCAAACGAGGGCGAGTAAATTGCAAGATTTGGCGATGGCCGGCCAGATTGACCTGTCCAAGCCTTTAATAGAACAACCAGAAGCCGGGCAGTCTCCGAAACAAACGAGCCCAGCGCCAGGTGGTGGGGATAAACAAACCTCTCCCACCCCTCCGTCACCTGGTCTCTCAGGTAGTCAAGGGATGAGCCCTTGCCCTAAGTGCGGCGCCCTTTTTAGTTCTCAAGATCAGTTGAGCGCCCATCAGCAGCTGTATTGCATGTTCGCAACGCCTATGGCAATTTTTCAAACGGCTTCCGAGCCCGGTCACGCCAAGAGTCCTCCTCCTGGCGACCCGCAGGACGGTGTCGCCAGGTCGAATAATGTACCTAAGAAAACCGGCTCACACATGTACAAACATCTCTTGGAAAGTTTCGGATTCGACTTAGTGATGCAATATAATGAGAGCCATCAGAGGCGACAGAGACAACAGCGCGAAGCCGAGGAAAAGGCAGCCAGTGAGGCCCAGACGCCGCCGCCGACGGCCACGATGCCCGCCTTGGAAGAGCCCGCTAACGAAACGGCGCCGACCGGGGATGTAAGTAAATCTACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTTCATAAAGATTTAGTGCCACTCGAATTCTTAGAAAAATATGCTCAACAGTTCAAAAACGAATACGAAAAGAAAACGGTGGTCGTGACGGCGGCGACGTCCTCAACACTAAACACCTTGCCCAGAGTGTCAACGCCGAGTGGAACGACGCCCACAACCACCATGCCCTCCACGTCCAGCCCCGCGGAGACCGCCACGCCTGAAAAGGAAGACGAGTCCAAGGAGACCTTGCACGCCAAGTTGAACCTTCAGACCCCGCCGGAGGCAACCTCGACGGCTCCCTCGACGCCGACGTCCTCCACGACCCCCGCCAGCAGCACCGACTCATTGCCGGCCAATATCCAGGCGATGATAGCACAGAGCATGGCCCAAAATCCTATGGCTTTAGCGCAACAAATGTCTGAAATGCAGGCAGCATTAAATGTGATGCAattgcaacagttaaatttcaaTCCTATGATGCAAATGATGGGCATGGGCTTGCCATTGGGTTTGAACGCATTGGCGGCGATGAATTTACAACCGCCTCTGGTTCCCCTAATGATGCCGCCCCCGCCTTATGATCCTATTTCGCAATTCGGGCCGCAGGATCAACAGGCCATGCTCGCAAAACAGCAGCAAGCGATGATGCAGCAACAAGCGGCCGTAAACGCTGCTGCCAACCAGAAACGCGCCAGAACGCGAATTACCGATGATCAATTGAAAATTTTGCGTGCGCACTTCGACATAAATAACTCACCTTCCGAAGAACAAATACACGAGATGGCATCCCAGAGTGGTTTACCTCCCAAAGTCATAAAGCACTGGTTCCGAAATACGTTGTTCAAGGAGAGGCAGCGTAACAAGGACAGTCCATATAACTTTAATAACCCACCGTCGACGACGCTTAATTTAGAGGAATACGAAAAAACAGGCGAAGCTAAAGTTATACCCCTTAACAGTTCAAGTAGCAGTATAGACGAAAACAAATCAAAAGACTCACCAACACCTATTCAACAAGAGATTAAAACTGAATTAAAAGAAGAGCCGTCTGACGACCCGCCAAAATACATCGAGGATAAAGTTCACGATTCTATGGACGAAAAGCTTAACATGTTTAACTTACCTTTAAATGTACAGCCGCCTCAGAGCCCTGCTACCTCGGTGGCTAGCTCGGACAACCAGAGCGTGTCGCAGCCCAGCACGCCGAACAATCTTACCCTTACCTCAATTATAGCGTCACAATTGGGTGATACGCTAACCACCAGCACGCCAACCATGAACATGTCCAGCATGTCGACACACCACGGTTTAACCAGCCCGATGTTACCACCGCCTAAACTTAACCAACAGAACTTTCCCAACCCTAACAATCTACAGGGTATGCTACCATTGACACCGAATCGCTGCCTCAGTCCGAACAGAGAATATAGCAATCCCGGAAGTCAAGGTTCCGGCGGGTCGACTGGCAAAAGAGCTAACCGCACGAGATTTACCGATTATCAGATAAAAGTGTTGCAagaatttttcgaaaataacGCTTACCCCAAAGACGATGACCTAGAATATCTATCGAAGTTGTTAAGCTTGAGTCCTAGAGTGATTGTGGTGTGGTTTCAAAATGCCCGACAGAAAGCTCGTAAAGTATACGAAAACCAACCAGCCGCCGAACCTGCCCCTGGCATTCCCGATGAGGCCGGTGCCAACAGATTTCAAAGAACGCCCGGCCTAAATTATCAATGCAAAAAATGTCTCCTAGTTTTCCAAAGATATTACGAATTAATACGACATCAAAAGACTCATTGCTTTAAAGAAGAAGACGCAAAAAGATCGGCGCAAGCTCAAGCGGCCGCCGCACAGATAGCGGCCGTTTTGAGCTCAGAGGACTCGAATTCAAGTACCACCGTCGAACAGTCACAACAATCACAACATCAGATGGTACAGCAACAGACTTCCATGCAACAGAATCCTCAATCCAACCCTGCCCACAGTCCAAGCCAGCCGAATCCTCCCACGACGCCAACACCAAGCCAATGCAATTATCCTCCTTCTTCCCCTTCCCCTTCGGAATCTAAAGAAAGCACGTTTCAGTGCGACAAATGCAATCTAGTTTTTCCTCGATTTGAACTTTGGAGGGAGCAtcagctagtacatctaatgaaTCCTAACCTTTTTCCAACTTATCCCCCAGATTCTCCATTTGGAATCCTACAACAACACGCTCAACTTCAGATGAACGCGAATTTGGGGGACTTAAAACCACAAAACAATACGACGCACCAAAATATTCCACATCCATTGATAAATATGCTGAACAACGTGACTAGCCAGAAAAGGAAAATCGACGATTTCGACGCTGAAAGCGATACCTCCGACCAACCGAAGGATAAGAGATTAAGAACTACAATTTTACCTGAACAGCTAGATTACTTGTACCAAAAATATCAAATCGAGAGTAACCCATCCAGAAAAATGTTAGAGAATATTGCTAGGGAGGTCGGTTTAAAGAAAAGGGTCGTTCAAGTTTGGTTTCAGAACACACGAGCTAGAGAGCGAAAAGGCCAATTCCGAGCTCACGCCCAAGTAATCAACAAGAGATGTCCGTTCTGTCCTGCTCTGTTCAAAGTGAAGTCAGCTTTAGAATCTCATTTAACAACGAAGCACGCCGATCAGTGCGCCAGAGGTGAAATTAACATAGACGCTTTACCTGATGAGGAAATCAGTCTCGAATCTGCACCGAGCTTGAGTTCAGGGGGCGACAATAAATTTCAACAACAGAACCCAAACATGATGCCACCACTTTTTCCTTCTCTTCATCCTGAAATGGAAAGTTCGATAAAGAAATATTACGAGGAGAGTATGAAGAGGTATATTACCGAATTACAAGCTCACGCTTCTTCGTCCAACGGCGACAAAAGCGAAATCAAATCCGAAAAAGGGGAAAGTGGTGAGATACCTTTAGATCTCTCCAAACCAGTAGACTTGTCAAGGCCGATGAAAGTATCCATGGACCATGAGCGTAATATTTGTGATCCTGGTCCGTTAACCGATCTCAGTGAACGATCTCTCTGCGACGAAAGGagtgattcgatgtcagaaaCTACAGAGTTCTATGATGACGAGAGTAATCCCACGTCGCCAGCCAGCAGTACCCAAAGCAACACTCAGAGAATGAACAGTGGCACCTCCGTAGGCGGTACGAAGCGATATCGCACGCAAATGTCCTCAGTCCAAGTGAAAGTGATGAAAATACTTTTTCACGACTATAAAACTCCCACCATGGCCGAATGTGAAAGCTTAGGCAAAGAAATTGGTTTGCCTAAGCGTGTGGTGCAAGTGTGGTTCCAAAACGCCAGGGCGAAAGAAAAGAAGGGCAAAATGGCGTTGCAAAAAGTGCTTGGTCAGTCAGACTCTGAAAATCCTCCGATGCCCGATGATTGCAGGTTCTGTAATTTCAAATACTCGCACAAATACTCGATTCAGGATCACATCTTCACCAAGACACACATAGCGAACGTACGAATGCACCTCGAGAGCCAACAAAGCAAAGAGCCCCCGGAGGGAGAGTTTACTGTACCACCTTTACCTGGAGCCTCGGGAGCTGTGACGGCGGATTCTACCACTAACCCACCGatgaatttgaataataacaCACATCTTCAGCTGTTACAAATGGCTGGGATGCAAATGGGAGGTGCTTCCAAAGGCGAGCAGGAGGAGAGTCCAGAGTCCCTGTTCCAGCAACTGTACGCCTTGGGGAACAACGCCAACTTTGGAGTGCAGAATCAATACGTACATCATGCGATGTTTGGGGCTAACGGTGAGTTGAATTTTTTCATTGGTTTTGCTAGTTTTCTAGAGTTTTACTGTTTTGTGGATATAGGTATAGTTCTTCATGTTTAG
Protein Sequence
MFFYSSTERRDSINSELSQIEASRDQVKSEPREEGDDANNSESGSPQHMCPFCEYSSDSEMRIQAHILAQHGTNNASMPEILFHCPLCQDAFKDRTNLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSLNQTQTTPNQIVSPTSVSSKESNKLEKSDPSHADAEPDLMSPVSDDTTESESERCGTCFKTFRNIDELCYHQNETGHLEIKQTPSGPGYMCWKKGCNQFFPTAHTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLRHDDNESGECDDSKELNTSQSLDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPVSPITGSTQPQNLTLTPKSSSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPEAGQSPKQTSPAPGGGDKQTSPTPPSPGLSGSQGMSPCPKCGALFSSQDQLSAHQQLYCMFATPMAIFQTASEPGHAKSPPPGDPQDGVARSNNVPKKTGSHMYKHLLESFGFDLVMQYNESHQRRQRQQREAEEKAASEAQTPPPTATMPALEEPANETAPTGDVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNTLPRVSTPSGTTPTTTMPSTSSPAETATPEKEDESKETLHAKLNLQTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAMLAKQQQAMMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVIPLNSSSSSIDENKSKDSPTPIQQEIKTELKEEPSDDPPKYIEDKVHDSMDEKLNMFNLPLNVQPPQSPATSVASSDNQSVSQPSTPNNLTLTSIIASQLGDTLTTSTPTMNMSSMSTHHGLTSPMLPPPKLNQQNFPNPNNLQGMLPLTPNRCLSPNREYSNPGSQGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIPDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQSQHQMVQQQTSMQQNPQSNPAHSPSQPNPPTTPTPSQCNYPPSSPSPSESKESTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPTYPPDSPFGILQQHAQLQMNANLGDLKPQNNTTHQNIPHPLINMLNNVTSQKRKIDDFDAESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEISLESAPSLSSGGDNKFQQQNPNMMPPLFPSLHPEMESSIKKYYEESMKRYITELQAHASSSNGDKSEIKSEKGESGEIPLDLSKPVDLSRPMKVSMDHERNICDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNTQRMNSGTSVGGTKRYRTQMSSVQVKVMKILFHDYKTPTMAECESLGKEIGLPKRVVQVWFQNARAKEKKGKMALQKVLGQSDSENPPMPDDCRFCNFKYSHKYSIQDHIFTKTHIANVRMHLESQQSKEPPEGEFTVPPLPGASGAVTADSTTNPPMNLNNNTHLQLLQMAGMQMGGASKGEQEESPESLFQQLYALGNNANFGVQNQYVHHAMFGANGELNFFIGFASFLEFYCFVDIGIVLHV