Basic Information

Insect: Rosalia funebris
Gene Symbol: ZFHX3
Assembly: GCA_037954035.1
Location: JAZFAV010000015.1:29499790-29515438[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0093 1.1 11.6 1.5 1 23 120 143 120 143 0.95

2 14 0.053 6.3 9.2 2.2 2 22 229 249 229 252 0.90

3 14 0.16 19 7.7 1.6 1 23 264 289 264 289 0.91

4 14 0.0074 0.89 11.9 1.6 1 23 307 329 307 329 0.97

5 14 0.0016 0.19 14.0 0.7 2 23 336 358 335 358 0.94

6 14 0.00042 0.051 15.8 3.1 1 23 467 491 467 491 0.92

7 14 0.013 1.5 11.1 0.6 1 22 511 532 511 535 0.89

8 14 0.0025 0.3 13.3 0.2 1 23 583 607 583 607 0.93

9 14 0.0023 0.28 13.4 0.1 2 21 669 688 668 689 0.94

10 14 0.75 89 5.6 2.5 2 19 816 833 815 838 0.90

11 14 0.00027 0.032 16.4 2.5 1 23 1405 1427 1405 1427 0.99

12 14 0.0019 0.22 13.8 0.3 1 23 1521 1543 1521 1543 0.98

13 14 0.015 1.8 10.9 0.4 2 23 1693 1715 1692 1715 0.96

14 14 0.59 70 5.9 3.5 2 23 1974 1997 1973 1997 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0093	1.1	11.6	1.5	1	23	120	143	120	143	0.95
2	14	0.053	6.3	9.2	2.2	2	22	229	249	229	252	0.90
3	14	0.16	19	7.7	1.6	1	23	264	289	264	289	0.91
4	14	0.0074	0.89	11.9	1.6	1	23	307	329	307	329	0.97
5	14	0.0016	0.19	14.0	0.7	2	23	336	358	335	358	0.94
6	14	0.00042	0.051	15.8	3.1	1	23	467	491	467	491	0.92
7	14	0.013	1.5	11.1	0.6	1	22	511	532	511	535	0.89
8	14	0.0025	0.3	13.3	0.2	1	23	583	607	583	607	0.93
9	14	0.0023	0.28	13.4	0.1	2	21	669	688	668	689	0.94
10	14	0.75	89	5.6	2.5	2	19	816	833	815	838	0.90
11	14	0.00027	0.032	16.4	2.5	1	23	1405	1427	1405	1427	0.99
12	14	0.0019	0.22	13.8	0.3	1	23	1521	1543	1521	1543	0.98
13	14	0.015	1.8	10.9	0.4	2	23	1693	1715	1692	1715	0.96
14	14	0.59	70	5.9	3.5	2	23	1974	1997	1973	1997	0.89

Sequence Information

Coding Sequence: ATGGCGGCGACTAAACAATTGTTCTTATTGTCGCAGGGGCCCGGTGTTTTAAGCTCCACAAAGATACCGTTAATCCCTGTCATTATTGTAACAATACCCACCCGAATTTTACCTctaaaaatgttcttttattcTCTTGCAGAGCGTATCAACTCCGAGCTCGGCCAGATGGAAGCGAATAGAGATCAGGTCAAATCCGAGCCCCGAGAAGAAGGCGAGGACATCAACAACAGCGAGAGCGGTTCGCCGCAGCACATGTGCCCGTTTTGCGAGTACAGCAGCGATTCGGAGATGCGTATCCAGGCGCACGTGCTCGCGCAGCACGGCACCAACAACTCCTCCATGCCGGAAATTATTTTCCACTGTCCCTTATGTCAGGACGGTTTCAAAGATCGCGGCCACTTAGAGCGCCACGTGATGCAAATACACTCCGTGAACAACGAGGGATTGCAACGGCTGCTGATGCTGGTAGATCAGAGCCACTGGCTAAACCAAACGTCTAGAACACCGACACCTAACAACTCTCTAAATCAAACCCAAACGACTCCCAATCAAATCGTATCCCCAACTTCAGTGTCTTCCAAAGAATCAAATAAACATGACAAGGGCGACGTTAGTCACGCCGACACCGAACCAGATCTAATGTCGCCTGCCAGCGATGACAACACCGAATTTGAGTCGGAGCGGTGCGGGACTTGCTTTAAGACATTTCGTAACATCGACGAGCTGTGCTACCATCAGAACGAAACCGGACACCTGGAGATTAAACAAACCCCCAGCGGACCGGGCTACATGTGCTGGAAAAAGGGATGCAATCAGTTTTTTCCTACAGCGCATACGTTACAAATGCATTTTAAGGAAGTGCACGCCAAGAATTCTATAACGAACATGTCGGTGTCCGAAAAACACGTGTACAAGTACCGGTGTAACCAGTGCTCCCTAGCTTTTAAGACTCTAGAAAAACTCCAGCTTCACTCTCAATATCACATGATAAGAGACGCTACCAAATGTGTGTTGTGTGGACGCAGCTTTAGATCGCTCGTTGCTCTCCACAAACACGTCGAAAGTGTGCATTCAGAATTGACAGATGAGGAACTGATCGCGTACAAGCAAAGCTTGATGAACAATCCGTTGCTATTGGCGGGACTGCAAGGGCAAGTACTGGACAGTTCGACGAATGACATTTTAAAGAAGGAGTCCATGCGTAACGACGACAACGAATCCGGCGAATGCGATGACAGTAAAGAGCTGAACACCAGTCAATCGCTTGACGATAGCAATCAGAACGATGGCGAAAATTCAGACGACAGCATCATTTATAAGGACCAGCAATTCCTGGAGGACTACCTAAATAGCCAGGCCATCGCGGAAGATAGTTACAATGATCCTAATAGGAAATACAAATGTCACCGGTGTAAAGTAGCTTTTACGAGACAAAGCTATTTGACGGCTCACAACAAAACTCTTTTACACCGTAAGGGCGAGAAACTAAGTTACCCTATGGAGAAATACCTGGACCCGAATCGGCCGTACAAATGTGACGTCTGCAAGGAGAGTTTCACACAGAAAAACATATTACTAGTGCACTACAACTCGGTCAGTCATTTGCACAAATTGAAAAGAGCCATGCAGGAACAAcagaacaataataataacccCCCGGTATCGCCTATTACTGGCACACAGCCGCAAAATTTGTCGCTCACGCCGAAAAGTTCATCGTCCGAGGACGACGACAAGAAGCGGTACCGGTGTAACATTTGCAAAGTAGCCTATACGCAAGGTAGCACTCTCGACATACACATGCGGAGTGTTCTTCACCAGACTCGAGCTAGTAAATTGCAAGACCTAGCGATGGCCGGCCAGATTGACTTGTCCAAGCCACTAATAGAGCAGCCAGAAGCCATGCAGTCTCCCAAGCAAACTAGTCCGGCGCCTGGGAGTGGGGAAAAACAGTCCTCTCCCACCCCTCCGTCACCTGGACTCTCAGGTAGCCAAGGGATGAGTTGTCCCAAGTGCGGGGCGCTGTTTAGTTCGCAAGATCAGTTAAGTGCCCATCAGCAGCTGTATTGCCTGTTCGCCACGCCGATGGCTGTTTTTCAAACAGCCCCAGAGCCCGGCCCAACGAAAAGCCCTCCGCCAAATGATTCGCAAGATGGTATCGTGAGATTGAATATCCCTAAGAAGACCAGCTCGCATATGTACAAACACCTATTGGAAAGCTTTGGATTTGACCTAGTGATGCAATATAATGAGAGCCATCAACGAAGGCAGCGGCAACAGCGCGAAGCCGAGGAGAAGGCCGCTAGCGAAGCCCAGACGCCTCCACCTACGGGGGTGCCCAGGACAGAAGAGACCGTCAACGAGACGGCCGTCGCAACCGTCGATGGTGCGGAGTCCAAGGAGGAGGACATAGAGACCAACCTACCTGAAGTAAGTAAATCCACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTTCATAAAGATTTAGTGCCACTCGAATTCTTAGAAAAGTATGCTCAACAGTTCAAAGACGAATACGAAAAGAAAACGGTGGTCGTGACGGCGGCGACGTCCTCGACGCTTAGCAGCATGCCCCGAGTGTCGACGCCCGGCGGGACGACGCCCATCACCACGGCGGCCTGCACGTCCAGTCCCGTAGAGGCGACTGTTCCAGATAAAGACGAACCCAAGGATGCCCTGCACGCTAAATTGAACCTTCAAACGCCGCCGGAAGCGACCTCGACGGCACCCTCGACGCCGACGTCGTCCACGACGCCAGCCAGCAGTACCGACTCTCTGCCGGCCAACATCCAGGCGATGATCGCGCAGAGCATGGCCCAGAACCCCATGGCCTTGGCGCAGCAAATGTCCGAAATGCAAGCGGCTTTGAATGTTATGCAACTGCAACAATTGAATTTCAATCCGATGATGCAGATGATGGGCATGGGCCTGCCTCTGGGTTTGAATGCATTGGCAGCGATGAATCTACAGCCGCCTCTGGTTCCTCTTATGATGCCGCCCCCGCCTTATGATCCCATTTCGCAATTCGGGCCACAAGATCAGCAGGCCATGCTAGCCAAACAGCAGGCCATGATGCAACAACAAGCGGCCGTGAACGCAGCCGCCAACCAGAAACGTGCGCGGACGCGCATCACAGACGATCAACTGAAAATCTTGCGCGCGCATTTCGACATCAACAACTCGCCGTCAGAAGAGCAAATCCACGAGATGGCGTCGCAGAGCGGTTTACCACCCAAAGTCATAAAACACTGGTTtagaaatacattatttaaagaacGTCAACGGAATAAAGACAGTccttataattttaacaatccTCCATCTACAACGTTAAATTTAGAAGAATACGAAAAAACGGGCGAAGCAAAAGTTATGCAGCTAAATAGCTCGGGTAGCAGCATAGAAGATAACAAATGTAAAGAACCCTTAACGCCACAATGCGACATAAAAACCGAAATGAAAGAGGAACCCTCGGACGATCAACATAAATACCTGGAAGACAAAATTCAGGAAGTTATGGATGAGAAACCTAACATGTTCAATTTACCGCTAAATTTGCAGCCCCCACAGAGCCCTGCAACCTCAGTGGCCAGCTCCGACAATCAGAGCGTATCGCAGCCCACCACGCCGAATAACCTCACACTTACATCGATTATAGCATCACAATTGGGCGACACGCTAACCACCAGCACCCCAAGCATGAACATGTCCAGTATGAGCTCCCACCACGGCCTGGCGAGTCCCATGTTACCACCGCCCAAACTCAACCAACAAAACTTTCCGAACCATAACAATTTACAAGGTATATTACCCTTAACGCCCAATCGCTGCCTCAGCCCCAGCCGAGAGTACAGCAACCCCGGAAGTCAGGGCTCGGGAGGGTCAACCGGAAAGAGGGCTAACCGCACTAGATTTACCGACTATCAAATCAAAGTGTTGCAAGAGTTCTTCGAAAACAATGCCTATCCTAAGGACGACGATTTGGAATACCTATCAAAATTACTGAATTTAAGTCCTAGAGTTATCGTTGTATGGTTCCAAAATGCTCGTCAGAAAGCTCGAAAAGTATACGAAAATCAGCCAGCTGCCGAACCAGCTCCTGGCATTCCCGATGAGGCAGGTGCTAATCGATTTCAAAGAACTCCCGGACTAAATTACCAGTGCAAGAAATGTCTGCTTGTTTTCCAGAGGTACTACGAACTAATCAGGCATCAAAAGACCCATTGCTTTAAGGAGGAAGACGCTAAAAGGTCGGCGCAGGCGCAAGCCGCGGCAGCACAAATCGCTGCCGTCTTAAGCTCTGAAGATTCGAATTCGAGTACAACTGTAGAACAGTCACAACAACCTCAACATCAGATGCAACAGCAACCTGTTCTTCAGCAAAATACGCAATCAAACCCCGCTCATAGTCCAGGCCAACCGAATCCTCCCACAACTCCAACGCCTAGTCAAGGCAACTATCCTCCCTCATGTCCTTCACCCTCCGAATCTAAAGAAAGTACATTTCAGTGCGATAAATGTAATCTAGTTTTTCCCCGATTCGAACTTTGGAGAGAACATCAGCTCGTCCACTTGATGAATCCTAACCTTTTTCCATCGTACCCCCCAGATTCTCCTTTTGGGATCCTACAACAACACGCGCAACTTCAACAACTAAACGCTAATTTGGGGGATTTAACTAAACCACCAAATAATGCAACTCCCCAAAATATTCCACATCCACTGATAAATATGCTGAACAACGTGACTGGTCCGAAAAGAAAGATCGACGAATTTGATGTAGAAAGCGACACTTCCGACCAGCCCAAAGATAAAAGGTTACGGACAACAATTTTACCAGAACAGCTAGATTATCTTTACCAAAAATACCAGATCGAGAGCAATCCTTCCAGAAAAATGCTCGAAAATATTGCGAGAGAGGTGGGACTGAAGAAAAGAGTGGTACAAGTGTGGTTCCAGAACACCCGAGCCCGAGAAAGGAAAGGACAATTTCGCGCTCATGCCCAGGTAATCAACAAGAGGTGTCCCTTTTGTCCCGCGCTTTTCAAAGTAAAATCAGCTTTAGAATCTCATTTAACCACCAAACACGCCGACCAGTGCGCTAGGGGTGAAATTAACATAGACGCTTTACCCGACGAAGAAATTAGTTTAGAATCCGCTCCAAGTTTGGGTTCCGGTGGTGACACTAAATTCCAGCAGCAGAACCCAAACATGATGCCACCACTTTTTCCTTCTCTTCACCCTGAAATGGAAAGTTCCATCAAGAAATACTACGAGGAGAGCATGAAGAGATATATCAGCGAATTGCAAGCTCACGCTTCGTCGTCCAATGGCGATAAAAGCGAAATCAAATCCGAAAAAGGGGAAAGTGGTGAGATTCCATTAGATCTCTCCAAGCCAGTCGATTTATCTAGACCCATGAAGGTGTCCATGGACCACGAGCGCAATATGTGCGATCCTGGTCCGCTAACTGATCTCAGCGAACGATCTCTATGCGATGAAAGAAGCGATTCGATGTCAGAGACCACAGAATTTTACGACGACGAAAGTAATCCAACATCACCAGCAAGCAGTACCCAAAGCAACACGCAGAAGGGTCCTAACAGCGGCACTTCCGTCGGAGGTACGAAGCGATTTCGCACGCAAATGTCGTCAGTTCAAGTGAAAGTGATGAAGATACTGTTCCACGATTATAAAACTCCAACGATGGCCGAATGTGAGAGTTTAGGTAGGGAGATCGGTTTGCCGAAACGTGTCGTACAGGTGTGGTTTCAAAATGCCAGAGCGAAAGAGAAGAAAGGCAAGATGGCATTGCAAAAGGCGCTCGGTCAGCCGGAAACCGATAATCCACCTTTGCCGGACGAATGTAAATTTTGCAACTTCAAATACTCTCACAAATATTCAATCCAAGATCATATTTTCACTAAAACTCACATAGCCAACGTGAGAATGCACCTGGAAAGTCAGAATAAGGAGGGGTCTGAAGGTGAATTCACAGTGCCGCCCTTGCCAGGAGCGTCCAGCGGTGTCACCGCGGATTCCACAACGAATCCGCCTCAGAATCTCAACAATAACACGCACCTTCAGTTGCTGCAAATGGCCGGAATGCAAATGGGTGCTGCGTCCAAGGGTGATCAGGAAGAGAGTCCAGAGTCGCTGTTCCAGCAGCTGTATGCCCTAGGAAATAACGCCAATTTTGGAGTGCAGAACCAGTATGTCCATCATGCGATGTTTGGTGCTAACGGTGAGTGGAATTTATAG
Protein Sequence: MAATKQLFLLSQGPGVLSSTKIPLIPVIIVTIPTRILPLKMFFYSLAERINSELGQMEANRDQVKSEPREEGEDINNSESGSPQHMCPFCEYSSDSEMRIQAHVLAQHGTNNSSMPEIIFHCPLCQDGFKDRGHLERHVMQIHSVNNEGLQRLLMLVDQSHWLNQTSRTPTPNNSLNQTQTTPNQIVSPTSVSSKESNKHDKGDVSHADTEPDLMSPASDDNTEFESERCGTCFKTFRNIDELCYHQNETGHLEIKQTPSGPGYMCWKKGCNQFFPTAHTLQMHFKEVHAKNSITNMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELIAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESMRNDDNESGECDDSKELNTSQSLDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPVSPITGTQPQNLSLTPKSSSSEDDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPEAMQSPKQTSPAPGSGEKQSSPTPPSPGLSGSQGMSCPKCGALFSSQDQLSAHQQLYCLFATPMAVFQTAPEPGPTKSPPPNDSQDGIVRLNIPKKTSSHMYKHLLESFGFDLVMQYNESHQRRQRQQREAEEKAASEAQTPPPTGVPRTEETVNETAVATVDGAESKEEDIETNLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKDEYEKKTVVVTAATSSTLSSMPRVSTPGGTTPITTAACTSSPVEATVPDKDEPKDALHAKLNLQTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAMLAKQQAMMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMQLNSSGSSIEDNKCKEPLTPQCDIKTEMKEEPSDDQHKYLEDKIQEVMDEKPNMFNLPLNLQPPQSPATSVASSDNQSVSQPTTPNNLTLTSIIASQLGDTLTTSTPSMNMSSMSSHHGLASPMLPPPKLNQQNFPNHNNLQGILPLTPNRCLSPSREYSNPGSQGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIPDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQPQHQMQQQPVLQQNTQSNPAHSPGQPNPPTTPTPSQGNYPPSCPSPSESKESTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQLNANLGDLTKPPNNATPQNIPHPLINMLNNVTGPKRKIDEFDVESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEISLESAPSLGSGGDTKFQQQNPNMMPPLFPSLHPEMESSIKKYYEESMKRYISELQAHASSSNGDKSEIKSEKGESGEIPLDLSKPVDLSRPMKVSMDHERNMCDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNTQKGPNSGTSVGGTKRFRTQMSSVQVKVMKILFHDYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKGKMALQKALGQPETDNPPLPDECKFCNFKYSHKYSIQDHIFTKTHIANVRMHLESQNKEGSEGEFTVPPLPGASSGVTADSTTNPPQNLNNNTHLQLLQMAGMQMGAASKGDQEESPESLFQQLYALGNNANFGVQNQYVHHAMFGANGEWNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00886822;
90% Identity: iTF_00886822;
80% Identity: iTF_01310144;