Basic Information

Insect: Stenurella melanura
Gene Symbol: ZFHX3_2
Assembly: GCA_963583905.1
Location: OY757309.1:100315244-100344377[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0032 0.45 13.3 0.8 1 23 83 106 83 106 0.95

2 14 0.064 9.1 9.2 2.2 2 22 191 211 191 214 0.90

3 14 0.19 28 7.7 1.6 1 23 226 251 226 251 0.91

4 14 0.0089 1.3 11.9 1.6 1 23 269 291 269 291 0.97

5 14 0.0019 0.28 14.0 0.7 2 23 298 320 297 320 0.94

6 14 0.00051 0.072 15.8 3.1 1 23 429 453 429 453 0.92

7 14 0.015 2.2 11.2 0.6 1 22 473 494 473 497 0.89

8 14 0.003 0.43 13.4 0.2 1 23 546 570 546 570 0.93

9 14 0.0031 0.44 13.3 0.0 2 21 633 652 632 653 0.94

10 14 0.9 1.3e+02 5.6 2.5 2 19 783 800 782 805 0.90

11 14 0.00032 0.046 16.4 2.5 1 23 1375 1397 1375 1397 0.99

12 14 0.0022 0.32 13.8 0.3 1 23 1491 1513 1491 1513 0.98

13 14 0.018 2.5 10.9 0.4 2 23 1661 1683 1660 1683 0.96

14 14 3.9 5.5e+02 3.6 3.2 3 23 1942 1964 1940 1964 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0032	0.45	13.3	0.8	1	23	83	106	83	106	0.95
2	14	0.064	9.1	9.2	2.2	2	22	191	211	191	214	0.90
3	14	0.19	28	7.7	1.6	1	23	226	251	226	251	0.91
4	14	0.0089	1.3	11.9	1.6	1	23	269	291	269	291	0.97
5	14	0.0019	0.28	14.0	0.7	2	23	298	320	297	320	0.94
6	14	0.00051	0.072	15.8	3.1	1	23	429	453	429	453	0.92
7	14	0.015	2.2	11.2	0.6	1	22	473	494	473	497	0.89
8	14	0.003	0.43	13.4	0.2	1	23	546	570	546	570	0.93
9	14	0.0031	0.44	13.3	0.0	2	21	633	652	632	653	0.94
10	14	0.9	1.3e+02	5.6	2.5	2	19	783	800	782	805	0.90
11	14	0.00032	0.046	16.4	2.5	1	23	1375	1397	1375	1397	0.99
12	14	0.0022	0.32	13.8	0.3	1	23	1491	1513	1491	1513	0.98
13	14	0.018	2.5	10.9	0.4	2	23	1661	1683	1660	1683	0.96
14	14	3.9	5.5e+02	3.6	3.2	3	23	1942	1964	1940	1964	0.89

Sequence Information

Coding Sequence: atgtTCTTTTATTCTTCCACAGAACGCAGAGATAGCATCAACTCCGAGCTTAGCCAAATCGAAGCGAGCAGGGATCAGGTTAAATCGGAACCTCGAGAGGACGGCGAAGATGCCAACAACAGCGAAAGCGGATCTCCGCAACACATGTGCCCGTTCTGCGAGTACAGCAGCGACTCGGAGATGCGCATACAAGCTCACATCCTAGCACAGCATGGCACCAATAGCGCCTCCATGCCCGAAATCCTTTTTCACTGTCCCTTATGTCAGGACGCCTTCAAGGACCGCACCAACCTGGAGCGGCACGTTATGCAAATACACTCGGTGAACAGCGAAGGCTTGCAGCGATTATTAATGCTAGTGGATCAAAGCCATTGGCTCAACCAAGCCTCAAGAACGCCAACACCGAACAATTCTCTAAATCAAACTCAAACGACGCCCAATCAAATCGTATCACCGACTTCAGTGTCTTCCAAAGAATCAAACAAGCTCGAGAAAAGTGACCCCAGCCACGTCGACGAACCAGACTTGATGTCGCCCGTCAGCGACGACACCACCGAGTCCGAGTCGGAGCGCTGCGGCACGTGCTTCAAGACATTTCGGAACATCGACGAACTGTGCTACCACCAAAACGAAACCGGACACCTGGAAATCAAGCAGACCCCCAGTGGACCGGGCTACATGTGCTGGAAGAAGGGATGCAACCAGTTTTTTCCAACAGCGCATACTTTACAGATGCATTTCAAGGAAGTACACGCCAAAAATTCGATCGCGAACATGTCGGTGTCAGAGAAGCACGTATACAAGTACAGATGCAACCAGTGCTCATTAGCGTTCAAGACTCTAGAAAAACTGCAACTACATTCTCAATATCACATGATCAGAGACGCTACAAAATGTGTGTTGTGTGGACGTAGCTTTCGATCACTAGTCGCGCTGCACAAGCATGTGGAAAGCGTGCACTCGGAATTAACGGACGAAGAATTGAACGCTTACAAGCAGAGCCTAATGAACAACCCGCTTCTATTAGCGGGGCTACAAGGGCAAGTGCTAGACAGTTCCACGAATGACATTCTAAAGAAAGAATCGCTGCGGCACGACGACAACGAGTCTGGTGAATGCGACGACAGCAAAGAACTGAACACTAGTCAATCGCTGGACGATAGCAATCAAAACGATGGCGAGAATTCAGACGATAGCATCATTTATAAGGACCAGCAGTTTTTAGAAGACTACCTGAACAGCCAGGCCATCGCCGAAGACAGCTACAATGATCCGAATAGAAAATACAAATGCCACCGTTGTAAAGTGGCCTTCACAAGACAAAGCTATTTAACCGCTCACAATAAAACTCTCTTACACCGAAAGGGTGAGAAACTAAGCTACCCTATGGAAAAATACCTGGATCCCAACCGGCCATATAAATGCGACGTATGTAAAGAGAGTTTtacgcaaaaaaatatattactcgTTCATTACAACTCCGTCAGTCATTTGCACAAATTAAAGCGGGCTATGCAAGAAcaacagaataataataataatccaccTGTGTCACCTATCACGGGCGGTACGCAGCCTCAAAATTTAACGTTAACGCCGAAAAGCTCGTCATCGGAGGAAGACGATAAGAAAAGGTACCGCTGCAATATCTGCAAAGTAGCGTACACGCAAGGTAGCACCCTCGACATTCATATGCGGAGCGTACTGCATCAGACTAGGGCGAGTAAATTGCAAGATTTGGCGATGGCCGGCCAGATTGACCTATCCAAGCCGTTAATAGAACAACCAGAAGCCGGGCAGTCTCCGAAGCAAACTAGTCCGGCGCCAGGTGGTGGGGATAAACAAACCTCTCCCACCCCTCCATCACCTGGTCTCTCAGGTAGTCAAGGGATGAGCCCTTGCCCTAAGTGCGGCGCCCTTTTTAGTTCTCAAGATCAGTTGAGTGCTCATCAGCAGCTGTATTGCATGTTTGCAACGCCTATGGCGATTTTTCAAACGGCGTCGGAGCCCGGACACGCCAAGAGCCCTCCTCCCGGCGATACTCAGGACGGTGTCGCGAGATCAAATAATGTACCTAAAAAGACTGGCTCGCACATGTACAAACACCTATTGGAGAGTTTCGGATTCGATTTAGTGATGCAATACAATGAAAGCCACCAGAGGCGACAGAGACAACAACGCGAGGCCGAGGAGAAGGCCGCCAGCGAGGCCCAGACGCCGCCGCCACCGCCGACCGCGATGCCCGCCTTGGAAGAGCCCTCTAACGAAACGGCGCCCGCCGTGGATGGTGCAGAGCCGAAGGCCGAGGAGGACATAGAAATCAACCTACCTGAAGTAAGTAAATCTACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTTCATAAAGATTTAGTGCCACTCGAATTCTTAGAAAAATATGCTCAACAGTTCAAAAACGAATACGAAAAGAAAACGGTGGTCGTGACGGCGGCGACGTCCTCCACGCTAAACAGCATGCCAAGAGTGTCGACACCTAGTGGAACTACGCCCACCACCTCAGCCGCCCCCACCTCCAGTCCCGCGGAGGCAGCCACCCCCGAAAAAGAGGATGAGTCCAAGGAAGCCTTACACGCCAAGCTGAACCTTCAGACTCCGCCGGAGGCTACGTCGACGGCCCCCTCGACGCCGACGTCGTCCACCACCCCTGCGAGCAGCACCGACTCGTTGCCGGCCAACATCCAGGCGATGATAGCACAGAGCATGGCCCAAAATCCTATGGCTTTAGCGCAACAAATGTCCGAAATGCAAGCGGCATTAAACGTGATGCAATTGCAACAACTTAATTTCAATCCGATGATGCAAATGATGGGCATGGGCTTGCCATTAGGTCTGAATGCATTGGCGGCGATGAATTTACAACCGCCTTTGGTTCCCCTAATGATGCCGCCTCCGCCGTACGATCCTATTTCGCAATTCGGGCCGCAGGATCAACAGGCCATGCTCGCAAAACAACAACAAGCGATGATGCAGCAACAAGCGGCCGTAAACGCTGCTGCCAACCAGAAACGCGCCAGGACGCGAATTACCGATGATCAATTGAAAATTTTGCGTGCACACTTCGACATAAACAACTCACCATCAGAAGAACAAATACACGAGATGGCATCGCAGAGCGGTCTGCCACCCAAAGTCATAAAGCATTGGTTTAGAAATACTTTATTCAAGGAGAGGCAGCGCAACAAAGACAGTCCCTATAACTTTAATAATCCACCGTCGACCACGCTTAATTTAGAAGAGTACGAAAAAACGGGAGAAGCGAAAGTCATGCCTCTTAACAGCTCAGGTAGCAGTATAGAAGAGAACAAATCTAAAGACTCGCCGACGCCCATTCAGCAAGaaattaaaactgaattaaaagAGGAGCCGTCAGACGAGCCACCAAAATACATCGAGGATAAAATTCACGATCCTATGGACGAAAAACCTAGCATGTTTAACTTGCCACTCAATTTACAGCCTCCTCAGAGCCCCGCTACCTCAGTGGCGAGCTCCGACAATCAGAGCGTGTCACAGCCGAGTACGCCGAACAATCTAACCCTTACCTCAATTATCGCGTCACAACTGGGTGACACGCTAACCACCAGCACGCCAACCATGAACATGTCCAGTATGTCAACACACCACGGTTTAACAAGCCCGATGTTACCACCACCTAAACTTAATCAACAGAATTTTTCCAACCCAAACAATCTACAGGGTATGCTCCCATTAACACCGAATCGCTGTCTTAGCCCTAACAGAGAATACAGCAATCCGGGAAGTCAAGGATCCGGTGGGTCGACCGGCAAAAGAGCTAACCGAACCAGGTTCACCGATTATCAGATAAAAGTACTGCAAGAATTTTTCGAGAATAACGCTTATCCCAAAGACGATGACCTAGAATACTTATCAAAGTTGTTAAGCTTGAGTCCTAGAGTAATCGTGGTGTGGTTTCAGAACGCTCGACAGAAGGCGCGTAAAGTATACGAAAATCAACCGGCTGCCGAACCTGCGCCTGGCATTCCCGACGAAGCCGGAGCTAATAGATTTCAGCGGACGCCCGGTCTAAATTACCAGTGCAAAAAATGTCTCCTAGTTTTCCAAAGATATTACGAGTTAATCCGACATCAAAAGACTCATTGCTTTAAAGAGGAAGATGCGAAAAGATCGGCGCAGGCCCAAGCGGCCGCTGCCCAGATAGCTGCAGTCTTGAGCTCGGAAGATTCGAACTCCAGTACCACTGTCGAACAGTCACAACAACCCCAGCATCAAATGATGCAACAACAGACTTCCATGCAACAAAACCCGCAATCTAATCCTGCCCACAGTCCACAACCTAACCCTCCCACGACGCCAACACCAAGCCAATGCAATTATCCCCCTTCCTCCCCATCCCCGTCAGAATCTAAAGAAAGTACGTTTCAGTGCGACAAATGCAACCTAGTTTTTCCTCGATTTGAACTTTGGAGGGAGCACCAGCTAGTCCACCTAATGAATCCTAATCTTTTTCCATCTTATCCCCCAGATTCTCCATTCGGAATCCTACAACAACATGCCCAACTTCAATTAAACGCCAATTTGGGGGATTTAAAGCCACAAAACAATTCGGCACAACAAAATATTCAACATCCGTTGATAAATATGTTGAACAATGTGACTAGCCAGAAAAGGAAAATCGATGATTTCGACGCTGAAAGTGACACGTCCGACCAACCGAAAGATAAAAGATTGAGGACTACAATTTTACCAGAACAGCTAGATTACTTGTATCAAAAATACCAAATCGAGAGCAACCCTTCCAGAAAAATGTTGGAGAACATCGCCAGGGAGGTCGGCTTAAAGAAAAGGGTCGTGCAAGTTTGGTTTCAGAACACCCGAGCTAGGGAACGAAAAGGTCAATTCCGAGCCCACGCTCAAGTAATCAACAAGAGGTGTCCATTCTGTCCCGCTCTGTTCAAGGTCAAGTCGGCTTTAGAATCTCACTTAACAACGAAGCACGCCGACCAGTGTGCCAGAGGTGAAATCAACATAGACGCCTTGCCCGATGAAGAAATCAGCCTTGAATCTGCACCAAGTTTAAGTTCCGGGGGTGACAATAAATTCCAGCAACAGAACCCAAACATGATGCCACCACTTTTCCCTTCTCTTCATCCTGAAATGGAAAGTTCGATAAAGAAATACTACGAGGAGAGCATGAAGAGGTATATTAGCGAATTGCAGGCGCACGCTTCTTCGTCCAACGGCGACAAAAGCGAAATCAAATCCGAAAAGGGGGAAAGTGGTGAGATACCTTTAGATCTCTCCAAACCAGTAGACCTATCAAGGCCGATGAAAGTATCCATGGACCATGAACGCAACATTTGTGATCCTGGTCCGTTAACCGATCTCAGTGAACGATCTCTTTGCGACGAGAGGAGTGATTCCATGTCAGAAACGACCGAGTTCTATGATGACGAGAGCAATCCCACGTCCCCAGCCAGCAGCACCCAAAGCAACACGCAGAGAATGAACAGTGGTACCTCCGTGGGGGGTACGAAGCGATTTCGCACGCAGATGTCATCGGTCCAAGTGAAAGTGATGAAAATACTTTTTCACGACTACAAAACCCCCACTATGGCCGAATGCGAAAGCTTGGGGAAAGAAATTGGTTTGCCTAAGCGCGTGGTGCAAGTGTGGTTTCAAAACGCCAGAGCGAAAGAAAAGAAGGGCAAGATGGCGTTACAAAAAGTCCTGGGTCAGCCAGACTCTGACAATCCGCAGATGCCGGACGACTGCAGGTTCTGCAATTTCAAATACTCGCACAAGTACTCGATTCAGGATCACATCTTCACCAAAACACACATAGCTAACGTAAGAATGCACCTGGAGAGTCAACAAAGCAAAGAAGTTGGCCCGGAAGGAGAATTTACGGTACCACCTCTACCTGGAGCGTCGGGAGCTGTGACCGCAGATTCTACCACTAATCCGCCGATGAATTTGAACAACAACACCCATCTTCAGCTGTTGCAAATGGCCGGGATGCAAATGGGAGGTGCTTCCAAAGGTGAACAGGAGGAGAGTCCAGAGTCCCTGTTCCAGCAACTGTACGCCTTGGGAAACAACGCCAACTTCGGAGTGCAGAATCAATACGTACACCATGCGATGTTTGGCGCTAACGGCAACCTGAAAACTGTTACAATTCATTCTCCGGTGGATGGTAGGTTCGTATGGAGTTGA
Protein Sequence: MFFYSSTERRDSINSELSQIEASRDQVKSEPREDGEDANNSESGSPQHMCPFCEYSSDSEMRIQAHILAQHGTNSASMPEILFHCPLCQDAFKDRTNLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSLNQTQTTPNQIVSPTSVSSKESNKLEKSDPSHVDEPDLMSPVSDDTTESESERCGTCFKTFRNIDELCYHQNETGHLEIKQTPSGPGYMCWKKGCNQFFPTAHTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLRHDDNESGECDDSKELNTSQSLDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPVSPITGGTQPQNLTLTPKSSSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPEAGQSPKQTSPAPGGGDKQTSPTPPSPGLSGSQGMSPCPKCGALFSSQDQLSAHQQLYCMFATPMAIFQTASEPGHAKSPPPGDTQDGVARSNNVPKKTGSHMYKHLLESFGFDLVMQYNESHQRRQRQQREAEEKAASEAQTPPPPPTAMPALEEPSNETAPAVDGAEPKAEEDIEINLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNSMPRVSTPSGTTPTTSAAPTSSPAEAATPEKEDESKEALHAKLNLQTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAMLAKQQQAMMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSIEENKSKDSPTPIQQEIKTELKEEPSDEPPKYIEDKIHDPMDEKPSMFNLPLNLQPPQSPATSVASSDNQSVSQPSTPNNLTLTSIIASQLGDTLTTSTPTMNMSSMSTHHGLTSPMLPPPKLNQQNFSNPNNLQGMLPLTPNRCLSPNREYSNPGSQGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIPDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQPQHQMMQQQTSMQQNPQSNPAHSPQPNPPTTPTPSQCNYPPSSPSPSESKESTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQLNANLGDLKPQNNSAQQNIQHPLINMLNNVTSQKRKIDDFDAESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEISLESAPSLSSGGDNKFQQQNPNMMPPLFPSLHPEMESSIKKYYEESMKRYISELQAHASSSNGDKSEIKSEKGESGEIPLDLSKPVDLSRPMKVSMDHERNICDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNTQRMNSGTSVGGTKRFRTQMSSVQVKVMKILFHDYKTPTMAECESLGKEIGLPKRVVQVWFQNARAKEKKGKMALQKVLGQPDSDNPQMPDDCRFCNFKYSHKYSIQDHIFTKTHIANVRMHLESQQSKEVGPEGEFTVPPLPGASGAVTADSTTNPPMNLNNNTHLQLLQMAGMQMGGASKGEQEESPESLFQQLYALGNNANFGVQNQYVHHAMFGANGNLKTVTIHSPVDGRFVWS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00886822;
90% Identity: iTF_00886822;
80% Identity: iTF_01368841;