Basic Information

Insect: Diabrotica virgifera
Gene Symbol: Zfhx4
Assembly: GCA_003013835.2
Location: ML015382.1:391201-419142[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.9 1e+03 3.2 0.3 1 23 48 71 48 71 0.88

2 15 0.11 28 8.1 0.4 2 23 85 107 84 107 0.93

3 15 0.11 28 8.1 2.1 2 22 191 211 191 214 0.90

4 15 1.4 3.7e+02 4.6 2.8 3 23 228 251 226 251 0.87

5 15 0.0067 1.7 11.9 1.6 1 23 269 291 269 291 0.97

6 15 0.0014 0.38 14.0 0.7 2 23 298 320 297 320 0.94

7 15 0.00038 0.099 15.8 3.1 1 23 428 452 428 452 0.92

8 15 0.011 2.9 11.2 0.6 1 22 472 493 472 496 0.89

9 15 0.0023 0.59 13.4 0.2 1 23 545 569 545 569 0.93

10 15 0.047 12 9.2 0.1 2 21 632 651 631 652 0.94

11 15 0.67 1.7e+02 5.6 2.5 2 19 785 802 784 807 0.90

12 15 0.00024 0.063 16.4 2.5 1 23 1374 1396 1374 1396 0.99

13 15 0.0017 0.43 13.8 0.3 1 23 1488 1510 1488 1510 0.98

14 15 0.013 3.4 11.0 0.4 2 23 1663 1685 1662 1685 0.96

15 15 0.093 24 8.3 3.0 3 23 1946 1968 1944 1968 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.9	1e+03	3.2	0.3	1	23	48	71	48	71	0.88
2	15	0.11	28	8.1	0.4	2	23	85	107	84	107	0.93
3	15	0.11	28	8.1	2.1	2	22	191	211	191	214	0.90
4	15	1.4	3.7e+02	4.6	2.8	3	23	228	251	226	251	0.87
5	15	0.0067	1.7	11.9	1.6	1	23	269	291	269	291	0.97
6	15	0.0014	0.38	14.0	0.7	2	23	298	320	297	320	0.94
7	15	0.00038	0.099	15.8	3.1	1	23	428	452	428	452	0.92
8	15	0.011	2.9	11.2	0.6	1	22	472	493	472	496	0.89
9	15	0.0023	0.59	13.4	0.2	1	23	545	569	545	569	0.93
10	15	0.047	12	9.2	0.1	2	21	632	651	631	652	0.94
11	15	0.67	1.7e+02	5.6	2.5	2	19	785	802	784	807	0.90
12	15	0.00024	0.063	16.4	2.5	1	23	1374	1396	1374	1396	0.99
13	15	0.0017	0.43	13.8	0.3	1	23	1488	1510	1488	1510	0.98
14	15	0.013	3.4	11.0	0.4	2	23	1663	1685	1662	1685	0.96
15	15	0.093	24	8.3	3.0	3	23	1946	1968	1944	1968	0.89

Sequence Information

Coding Sequence: ATGTTCTTTTATTCTCCAACAGAGCGAAGAGATAGTATCAATTTGGAACTAAGTCAGATTGAAGCGAGTCGAGAGCAAGTCAAATCCGAACCACGAGAAGAAAACGACGAAGCTAATAATAGCGAGAGTGGCAATTCTCAGCACATGTGCCCGTTCTGTGATTATAGTAGCGATTCTGAAATGCGCATTCAAGCACATATTCTCGCCCAACACGGTACAAATAACACTTCCATGCCTGAACAACCCCCGTTGCACTGCCCTCTTTGTCAGGATGTTTTTAAAGACCGATTATTGCTCGAACGTCACGTTATGCAGATACACTCTGTAAACAGCGAAGGTCTGCAGCGATTGCTTATGCTGGTCGATCAAAGTCATTGGTTGAATCAGACTTCTCGAACGCCAACTCCCAACAATTCGATTAATCAGTCGCAGACGACACCTAATCAAATCGTATCACCAAACTCAGTGTCTTCCAAAGAATCCAACAAGTTCGAGAAAACCGACATAAGCCAAATTGATGTCGATTTACTCTCGCCTAATAGTGACGATAATACCGAATCAGAGTCTGAACGATGTGGCACGTGTTTTAGGACGTTTCGGAATATAGACGAATTGTGTTATCATCAGAACGAAACCGGTCACTTAGAAATAAAACAGACGCCGAGTGGGCCGGGATATCTTTGCTGGAAAAAGGGCTGTAATCATTTTTTTCCTACTGCACATACGTTACAAATGCATTTTAAAGAAGTCCATGCCAAAAATTCAATAGCAAATATGTCTGTGTCCGAAAAACACGTGTATAAATATAGATGCAATCAGTGTTCTTTGGCTTTTAAAACGTTAGAAAAACTACAATTACATTCTCAATACCACATGATCAGAGATGCCACAAAATGTGTCTTGTGTGGACGAAGTTTTAGATCACTTGTAGCATTGCACAAACACGTTGAAAGTGTTCACTCCGAATTAACAGACGACGAATTAAATGCTTACAAACAAAGTCTAATGAACAATCCTTTATTACTGGCCGGACTACAAGGTCAAGTTTTAGACAGCTCAACAAACGACATCTTAAAAAAGGAATCTCTACGCACTGAAGATGATTCCGCGGAATGTGACGAGAGTAAAGAGTTAAACAGTAGTCAATCAGTTGACGATATTAATCAAAATGACGGCGAAAACTCAGATGACAGTATCATATATAAAGATCAACAATTCTTGGAAGATTACCTGAATAGTCAAGCTATTGCAGAAGACAGTTATAACGATCCAAATAGAAAATATAAATGCCACCGTTGTAAAGTCGCCTTTACAAGACAAAGTTATTTGACCGCTCACAATAAAACCCTTTTACACCGAAAGGGTGAGAAACTAAGTTACCCTATGGAAAAATATCTCGATCCTAACCGACCCTATAAATGTGATGTCTGTAAAGAGAGCTTTACTCAAAAAAATATCCTTCTTGTTCATTATAATTCTGTGAGTCATTTGCATAAATTAAAGAGAGCGATGCAAGaacaacaaaataataataataacccaCCTGTATCACCCGTTATGAGCGGTACACAACCACAAAATTTAACTTTAACCCCTAAAAGTACGTCGTCTGAAGAAGACGATAAAAAGAGATATCGGTGCAATATTTGTAAAGTAGCATATACACAAGGCAGTACGTTAGATATACATATGAGAAGTGTTTTACATCAAACGAGAGCGAGTAAATTGCAAGATTTGGCACTGTCCGGTCAGATCGACCTGTCGAAACCATTAATAGAACAACCCGAAGCCATGCAGTCTCCGAAACAAAGCTCTCCGGCGCCAGGTAGTGGGGACAAACAACCCTCTCCCACCCCACCATCACCTGGGCTCTCAGGTAGTCAGGGGATGATGAGTTGTTCTAAGTGCGGTGCACTATTCGGTTCGCAAGATCAGTTGAGTGCCCATCAGCAGCTGTACTGTATGTTTGCAACGCCTATGGCGATCTTTCAAGGGGCGCACGAACCAAGTCAAGCTAAAAGTCCACCTCCGAGCGATAATCCAGAAGGCGGTATAAAAGTTAATATTATACCGAAAAAATCAGGCTCGCATATGTATAAACATTTACTTGAAAGTTTCGGATTTGATCTAGTAATGCAATACAACGAAAGCCATCAACGGCGACAGCGACaacagcagcgagaagcggaagaAAATGCCGCCGCCGCCAATGTAGTGTTACAATCTTCACCGCCCCCAGTCCAGACAGTCCCGCAGGAGCCGCCCAGTGAGACGGTGCCAGTAGCCGCTGAGGGTGCCGAGACTAAGGCTGAGGAGGACATAGAAACCAACCTACCTGAAGTAAGTAAATCTACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTTCATAAAGATTTAGTGCCACTAGAATTCTTAGAAAAATATGCTCAACAGTTCAAAACCGAATACGAAAAGAAAACTGTGGTGGTGACAGCGGCGACTTCCTCGACCCTCAACACCGTGCCTACAGTTTCGACTCCTGGTCCAACTCCACCCAGTTCCTCGACGGCCGTGACGTCCAGCCCCACCGAAAATTCCACGCCGGAGAAGGCGGATGAATCGAAAGAAACTTTACATGCCAAACTTAACCTACAAACTCCACCAGAGCCTACCTCCACGGCCCCTTCGACCCCAACTTCGTCGACAACTCCTGCCAGCAGTACAGATTCAATACCAGCCAATATTCAAGCCATGATAGCTCAAAGTATGGCACAAAATCCAGTGGCTTTGGCCCAACAAATGTCAGAAATGCAGGCAGCCCTAAACGTCATGCAACTTCAACAACTTAATTTCAATCCTATGATGCAGATGATGGGTATGGGACTGCCGTTGGGATTAAACGCTTTGGCTGCGATGAACCTTCAGCCGCCTCTTGTGCCATTGATGATGCCGCCTCCGCCTTTCGATCCCATTTCGCAGTTCGGACCCCAGGATCAACAGAGTATGATGGCCAAACAACAAGCTATGATGCAACAACAAGCCGTTGTCAGCGCAGCGGCTAATCAGAAACGAGCCAGGACGCGAATTACCGATGATCAACTGAAAATTTTACGTGCTCACTTCGACATCAACAACTCTCCGTCGGAAGACCAAATTCACGAGATGGCATCACAAAGTGGCTTACCGCCGAAAGTTATAAAACACTGGTTTAGAAACACATTGTTCAAAGAACGACAACGTAATAAAGATAGTCCGTACAATTTTAACAATCCACCTTCAACTACATTAAATTTAGAAGAATACGAAAAAACTGGTGAAGCTAAAGTAATGCCCTTGAACAGCTCGGGGAGCAGCATTGAAGAGAATAAGTCAAAAGAATCACCAAAACTTTCGCAAGAAATTAAACACGAATTAAAAGAGGAACCTGTCGATGACTTTCCCAAACTAAACGAAGAGAAAATACAAGAACCTATAGACGAAAAACCTAACATATTTAACTTACCAGTAAACTTGCAACAAGCACAAAGTCCAGCGACGTCTATTGCCAGTTCAGATAACCAAAGTGTATCACAGCCAAGTACACCGAATAATCTCACCCTGACTTCAATCATTGCATCTCAGTTAGGTGATACCTTAACTACGAGTACACCTACTATGAATATGGCCAGCTTATCATCCCATCATGGTCTTACAAGTCCTATGTTGCCGCCTCCTAAACTTAACCAACAAAATTTTCCTAATCCAAACAACCTTCAAGGAATGCTACCCCTTACTCCCAACCGGTGCCTAAGCCCTAGCCGAGACTACAGCAATCCTGGGAGTCAGGGATCTGGAGGTTCAACTGGAAAAAGAGCAAACCGTACTAGATTTACCGATTatcaaataaaagtattacaagAATTCTTCGAAAATAACGCTTACCCAAAAGATGACGATCTCGAATATCTATCGAAACTACTGAATCTTAGTCCACGGGTTATAGTAGTTTGGTTTCAAAACGCTCGCCAAAAAGCACGAAAAGTATACGAAAACCAACCAGCAGTTGAGCCCGCACCTGGAATTGACGAAGCTGGAGCAAATAGATTTCAAAGAACTCCTGGACTAAATTACCAATGTAAAAAGTGTCTACTGGTATTCCAAAGATACTACGAACTAATTCGACATCAGAAAACGCACTGCTTTAAAGAAGAAGATGCAAAACGTTCAGCACAAGCTCAAGCAGCAGCAGCACAAATAGCCGCTGTATTGAGTTCAGAAGATTCAAATTCGAGTACAACTGTAGAACAATCTCAACAACATCAGATGCCTCCTCAAAGTGGATTACCGACTCTACCTCAACCCAACCTTACACAAAGTCCCAATCATCCTACTGCTCCAACAACTCCTACCCCAAGCCAAGGAAATTATCCCCCAACATCACCTTCTCCTTCTGAATCCAAAGAAAGTACCTTTCAGTGCGATAAATGCAATCTAGTTTTTCCTCGATTTGAACTTTGGCGAGAGCATCAACTTGTTCACTTAATGAATCCTAACCTTTTTCCATCATATCCCCCAGATTCTCCCTTTGGGATCCTTCAGCAGCATGCCCAACTACAACAACTAAACGCTAATTTGGGGGATATGAATAAACAACCGAACAATGTTGGGAACATACCGCAACAAAACCTTCAGCATCCTCTCATcaatatgttaaataatgttgctggacaaaaaagaaaagttgatgaATTTGATGCTGAAAGTGACACTTCTGATCAACCCAAAGATAAAAGACTTAGAACCACAATACTACCTGAGCAACTAGATTATCTTTATCAAAAATATCAGGTAGAAAGTAATCCATCCAGAAAAATGTTAGAAAATATTGCAAGAGAAGTGGGTTTAAAAAAGAGAGTGGTTCAAGTATGGTTTCAGAATACCAGAGCCAGAGAAAGAAAAGGGCAATTTAGAGCCCATGCTCAAGTAATTAATAAAAGATGTCCGTTTTGTCCGGCCCTATTTAAAGTTAAGTCTGCTCTAGAATCTCATTTAACCACCAAACACGCAGATCAGTGCGCTAGAGGTGAAATAAATATTGATGCGTTACCTGACGAAGAGATAAGCCTTGAATCAGCTCCAAGTTTGAGTTCAGGAGGCGAAAACAAAAATCAGCCTCCAAATTCAAACATGGTACCCCCTCTATTTCCATCACTTCATCCCGATATGGAGAACTCCATAAAAAAGTATTATGAAGAAAGTATGAAGCGGTATATTAGTGAATTACAAGCGCATGCTGCCGCATCAAATGGTgataaaagtgaaataaaatcGGAGAAACCTGAGGGTGTAGAAATCCCTTTAGATTTATCTAAGCCAGTAGATCTGTCTCGACCAATGAAAGTTTCTATGGATCACGAACGAAATGTTTGTGATCCAGGCCCATTAACTGATCTCAGCGAGCGTTCTTTATGTGATGAACGTAGCGACTCTATGTCTGAAACTACGGAATACTACGACGATGAAAGTAATCCAACCTCACCTGCCAGTAGTACTCAAAGCAACACCCAAAAGCAAATGAATAGTAGCGGTGGTTCACAGGGTGGCAATAAACGTTACCGAACTCAAATGTCTTCAGTCCAGGTGAAAGCTATGAAAATTTTGTTCAATGACTACAAAACACCGACAATGGCTGAATGTGAAAACCTAGGAAGAGAAATTGGTCTGCCCAAACGAGTTGTTCAAGTATGGTTTCAAAATGCACGAGCCAAAGAAAAGAAAGGCAAGTTAGCCTTACAAAAAGCTTTAGGCCAAAACGAAGGAGAAACCAATGCGATGCCTGATGACTGCAAGTACTGTAACTTCAAATATTCTCACAAGTACTCAGTTCAAGACCACATCTTTACCAAATCACACATAGCCAATGTGAAGATGCATCTAGAAAACCAACATAAAGATGTCGGTCCCGAGAACGAATTCACTGTGCCATCAATACCTGGGGCTTCGGGTGCCGTCTCAGCCGATTCCACCACCAACCCTCAGCAGAATGTTAACAACAACAGCCACTACCAGCTGCTCCAAATGTCTGGCGTTCAAATGGGGAACATGGCTAAAGGTGAACAGGAGGAGAATCAAGAGAACCTCTTCCAGCAATTCTACCAACTCGGCAACAATGCAAACTACGGTGTTCAAAACCAGTACGTTCATCATGCGATGTTTGGCGCTAATGGTGAgtaa
Protein Sequence: MFFYSPTERRDSINLELSQIEASREQVKSEPREENDEANNSESGNSQHMCPFCDYSSDSEMRIQAHILAQHGTNNTSMPEQPPLHCPLCQDVFKDRLLLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQTSRTPTPNNSINQSQTTPNQIVSPNSVSSKESNKFEKTDISQIDVDLLSPNSDDNTESESERCGTCFRTFRNIDELCYHQNETGHLEIKQTPSGPGYLCWKKGCNHFFPTAHTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDDELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLRTEDDSAECDESKELNSSQSVDDINQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPVSPVMSGTQPQNLTLTPKSTSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLALSGQIDLSKPLIEQPEAMQSPKQSSPAPGSGDKQPSPTPPSPGLSGSQGMMSCSKCGALFGSQDQLSAHQQLYCMFATPMAIFQGAHEPSQAKSPPPSDNPEGGIKVNIIPKKSGSHMYKHLLESFGFDLVMQYNESHQRRQRQQQREAEENAAAANVVLQSSPPPVQTVPQEPPSETVPVAAEGAETKAEEDIETNLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKTEYEKKTVVVTAATSSTLNTVPTVSTPGPTPPSSSTAVTSSPTENSTPEKADESKETLHAKLNLQTPPEPTSTAPSTPTSSTTPASSTDSIPANIQAMIAQSMAQNPVALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDPISQFGPQDQQSMMAKQQAMMQQQAVVSAAANQKRARTRITDDQLKILRAHFDINNSPSEDQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSIEENKSKESPKLSQEIKHELKEEPVDDFPKLNEEKIQEPIDEKPNIFNLPVNLQQAQSPATSIASSDNQSVSQPSTPNNLTLTSIIASQLGDTLTTSTPTMNMASLSSHHGLTSPMLPPPKLNQQNFPNPNNLQGMLPLTPNRCLSPSRDYSNPGSQGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAVEPAPGIDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQHQMPPQSGLPTLPQPNLTQSPNHPTAPTTPTPSQGNYPPTSPSPSESKESTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQLNANLGDMNKQPNNVGNIPQQNLQHPLINMLNNVAGQKRKVDEFDAESDTSDQPKDKRLRTTILPEQLDYLYQKYQVESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEISLESAPSLSSGGENKNQPPNSNMVPPLFPSLHPDMENSIKKYYEESMKRYISELQAHAAASNGDKSEIKSEKPEGVEIPLDLSKPVDLSRPMKVSMDHERNVCDPGPLTDLSERSLCDERSDSMSETTEYYDDESNPTSPASSTQSNTQKQMNSSGGSQGGNKRYRTQMSSVQVKAMKILFNDYKTPTMAECENLGREIGLPKRVVQVWFQNARAKEKKGKLALQKALGQNEGETNAMPDDCKYCNFKYSHKYSVQDHIFTKSHIANVKMHLENQHKDVGPENEFTVPSIPGASGAVSADSTTNPQQNVNNNSHYQLLQMSGVQMGNMAKGEQEENQENLFQQFYQLGNNANYGVQNQYVHHAMFGANGE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00886822;
90% Identity: iTF_00436299;
80% Identity: iTF_00436299;